{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:29:57Z","timestamp":1792175397702,"version":"4.4.0"},"reference-count":117,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11822201"],"award-info":[{"award-number":["11822201"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11827803"],"award-info":[{"award-number":["11827803"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12172034"],"award-info":[{"award-number":["12172034"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U20A20390"],"award-info":[{"award-number":["U20A20390"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["7212205"],"award-info":[{"award-number":["7212205"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["B13003"],"award-info":[{"award-number":["B13003"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.actbio.2023.08.040","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T20:51:13Z","timestamp":1692996673000},"page":"185-201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"special_numbering":"C","title":["In vitro fatigue behavior and in vivo osseointegration of the auxetic porous bone screw"],"prefix":"10.1016","volume":"170","author":[{"given":"Lizhen","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiwen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7408-4460","authenticated-orcid":false,"given":"Jeong Hun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7934-1400","authenticated-orcid":false,"given":"Jinglong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuezheng","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott J","family":"Hollister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0001","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3928\/01477447-20121217-02","article-title":"History of the orthopedic screw","volume":"36","author":"Roberts","year":"2013","journal-title":"Orthopedics"},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0002","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1243\/PIME_PROC_1992_206_261_02","article-title":"Revision of cemented fixation and cement-bone interface strength","volume":"206","author":"Rosenstein","year":"1992","journal-title":"Proc. Inst. Mech. Eng. Part H"},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0003","doi-asserted-by":"crossref","first-page":"79","DOI":"10.14245\/kjs.2012.9.2.79","article-title":"Clinical efficacy of bone cement augmented screw fixation for the severe osteoporotic spine","volume":"9","author":"Seo","year":"2012","journal-title":"Korean J. Spine"},{"issue":"5","key":"10.1016\/j.actbio.2023.08.040_bib0004","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.spinee.2004.02.006","article-title":"Pedicle screw fixation strength: pullout versus insertional torque","volume":"4","author":"Inceoglu","year":"2004","journal-title":"Spine J."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.spinee.2010.09.024","article-title":"Instrumentation of the osteoporotic spine: biomechanical and clinical considerations","volume":"11","author":"Ponnusamy","year":"2011","journal-title":"Spine J."},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0006","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.spinee.2012.01.014","article-title":"Assessment of pedicle screw pullout strength based on various screw designs and bone densities-an ex vivo biomechanical study","volume":"12","author":"Kim","year":"2012","journal-title":"Spine J."},{"issue":"5","key":"10.1016\/j.actbio.2023.08.040_bib0007","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1002\/jor.23771","article-title":"Additive manufactured push-fit implant fixation with screw-strength pull out","volume":"36","author":"van Arkel","year":"2018","journal-title":"J. Orthop. Res."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0008","doi-asserted-by":"crossref","first-page":"10441","DOI":"10.1038\/s41598-020-67489-2","article-title":"Use of longer sized screws is a salvage method for broken pedicles in osteoporotic vertebrae","volume":"10","author":"Hsieh","year":"2020","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.actbio.2023.08.040_bib0009","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21103628","article-title":"Three-dimensional printed porous titanium screw with bioactive surface modification for bone-tendon healing: a rabbit animal model","volume":"21","author":"Huang","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0010","first-page":"2371","article-title":"Prevention and treatment of bone cement-related complications in patients receiving percutaneous kyphoplasty","volume":"8","author":"Zhang","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0011","first-page":"537","article-title":"Four cases with rare complications of intramedullary screw fixation for jones fracture","volume":"74","author":"Morimoto","year":"2020","journal-title":"Acta Med. Okayama"},{"issue":"4","key":"10.1016\/j.actbio.2023.08.040_bib0012","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.medengphy.2016.01.006","article-title":"Screw insertion in trabecular bone causes peri-implant bone damage","volume":"38","author":"Steiner","year":"2016","journal-title":"Med. Eng. Phys."},{"issue":"7","key":"10.1016\/j.actbio.2023.08.040_bib0013","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1002\/jor.24286","article-title":"Bone resorption triggered by high radial stress: the mechanism of screw loosening in plate fixation of long bone fractures","volume":"37","author":"Feng","year":"2019","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.actbio.2023.08.040_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2020.108994","article-title":"Fatigue behavior and osseointegration of porous Ti-6Al-4V scaffolds with dense core for dental application","volume":"195","author":"Xiong","year":"2020","journal-title":"Mater. Des."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0015","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/prd.12179","article-title":"Osseointegration of titanium, titanium alloy and zirconia dental implants: current knowledge and open questions","volume":"73","author":"Bosshardt","year":"2017","journal-title":"Periodontology 2000"},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0016","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/prd.12254","article-title":"Research on implants and osseointegration","volume":"79","author":"Guglielmotti","year":"2019","journal-title":"Periodontol 2000"},{"issue":"3","key":"10.1016\/j.actbio.2023.08.040_bib0017","first-page":"458","article-title":"Additive manufacturing of biodegradable porous orthopaedic screw","volume":"5","author":"Dhandapani","year":"2020","journal-title":"Bioact. Mater."},{"issue":"14","key":"10.1016\/j.actbio.2023.08.040_bib0018","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.3390\/ma13143061","article-title":"Enhancement of bone ingrowth into a porous titanium structure to improve osseointegration of dental implants: a pilot study in the canine model","volume":"13","author":"Hong","year":"2020","journal-title":"Materials"},{"issue":"10","key":"10.1016\/j.actbio.2023.08.040_bib0019","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1002\/jor.24037","article-title":"Improvement of bone-tendon fixation by porous titanium interference screw: a rabbit animal model","volume":"36","author":"Tsai","year":"2018","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.actbio.2023.08.040_bib0020","doi-asserted-by":"crossref","first-page":"45360","DOI":"10.1038\/srep45360","article-title":"Laser beam melting 3D printing of Ti6Al4V based porous structured dental implants: fabrication, biocompatibility analysis and photoelastic study","volume":"7","author":"Yang","year":"2017","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.actbio.2023.08.040_bib0021","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/ID.0b013e31829b17b5","article-title":"Bone ingrowth and initial stability of titanium and porous tantalum dental implants: a pilot canine study","volume":"22","author":"Kim","year":"2013","journal-title":"Implant Dent."},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0022","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/clr.12792","article-title":"Influence of the implant diameter and bone quality on the primary stability of porous tantalum trabecular metaldental implants: an in vitro biomechanical study","volume":"29","author":"Romanos","year":"2018","journal-title":"Clin. Oral. Implants Res."},{"key":"10.1016\/j.actbio.2023.08.040_bib0023","article-title":"Laser beam melting 3D printing of Ti6Al4V based porous structured dental implants: fabrication, biocompatibility analysis and photoelastic study","volume":"7","author":"Yang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2023.08.040_bib0024","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.clinbiomech.2017.08.001","article-title":"Immediate mechanical stability of threaded and porous implant systems","volume":"48","author":"Kim","year":"2017","journal-title":"Clin. Biomech."},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0025","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1177\/0954411918816114","article-title":"Studies on the performance of selective laser melting porous dental implant by finite element model simulation, fatigue testing and in vivo experiments","volume":"233","author":"Wang","year":"2019","journal-title":"Proc. Inst. Mech. Eng. Part H J. Eng. Med."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0026","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jfma.2019.07.023","article-title":"3D laser-printed porous Ti6Al4V dental implants for compromised bone support","volume":"119","author":"Tu","year":"2020","journal-title":"J. Formos. Med. Assoc."},{"issue":"10","key":"10.1016\/j.actbio.2023.08.040_bib0027","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1177\/0885328220957902","article-title":"Mechanical properties and osteoblast proliferation of complex porous dental implants filled with magnesium alloy based on 3D printing","volume":"35","author":"Zhang","year":"2021","journal-title":"J. Biomater. Appl."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0028","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s13018-020-01764-w","article-title":"Design a novel integrated screw for minimally invasive atlantoaxial anterior transarticular screw fixation: a finite element analysis","volume":"15","author":"Zhang","year":"2020","journal-title":"J. Orthop. Surg. Res."},{"issue":"9","key":"10.1016\/j.actbio.2023.08.040_bib0029","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1108\/RPJ-01-2022-0006","article-title":"Mechanical and biological behaviour of additive manufactured biomimetic biodegradable orthopaedic cortical screws","volume":"28","author":"Agarwal","year":"2022","journal-title":"Rapid Prototyp. J."},{"issue":"11","key":"10.1016\/j.actbio.2023.08.040_bib0030","doi-asserted-by":"crossref","DOI":"10.3390\/ma15113903","article-title":"Approach to the fatigue and cellular behavior of superficially modified porous titanium dental implants","volume":"15","author":"Trueba","year":"2022","journal-title":"Materials"},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0031","article-title":"The hydroxyapatite modified 3D printed poly L-lactic acid porous screw in reconstruction of anterior cruciate ligament of rabbit knee joint: a histological and biomechanical study","volume":"24","author":"Wang","year":"2023","journal-title":"BMC Musculoskelet. Disord."},{"key":"10.1016\/j.actbio.2023.08.040_bib0032","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.msec.2015.11.025","article-title":"Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique","volume":"59","author":"Hara","year":"2016","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.actbio.2023.08.040_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2019.108424","article-title":"A novel auxetic structure based bone screw design: tensile mechanical characterization and pullout fixation strength evaluation","volume":"188","author":"Yao","year":"2020","journal-title":"Mater. Des."},{"key":"10.1016\/j.actbio.2023.08.040_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2021.104386","article-title":"Biomechanical design and analysis of auxetic pedicle screw to resist loosening","volume":"133","author":"Yao","year":"2021","journal-title":"Comput. Biol. Med."},{"issue":"3","key":"10.1016\/j.actbio.2023.08.040_bib0035","article-title":"Metallic meta-biomaterials: a critical review of fatigue behaviors","volume":"8","author":"Huang","year":"2023","journal-title":"J. Sci. Adv. Mater. Devices"},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0036","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1054\/arth.2002.32699","article-title":"Average patient walking activity approaches 2 million cycles per year - pedometers under-record walking activity","volume":"17","author":"Silva","year":"2002","journal-title":"J. Arthroplast."},{"key":"10.1016\/j.actbio.2023.08.040_bib0037","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jmbbm.2016.10.003","article-title":"How does tissue regeneration influence the mechanical behavior of additively manufactured porous biomaterials?","volume":"65","author":"Hedayati","year":"2017","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0038","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s10439-019-02369-z","article-title":"Partial bone formation in additive manufactured porous implants reduces predicted stress and danger of fatigue failure","volume":"48","author":"San Cheong","year":"2020","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.actbio.2023.08.040_bib0039","series-title":"Proceedings of the Conference on Health Monitoring of Structural and Biological Systems IX","article-title":"Bone remodeling in additive manufactured porous implants changes the stress distribution","author":"Cheong","year":"2020"},{"key":"10.1016\/j.actbio.2023.08.040_bib0040","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.actbio.2018.12.038","article-title":"Mechanical performance of additively manufactured meta-biomaterials","volume":"85","author":"Zadpoor","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0041","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jmbbm.2014.12.015","article-title":"Relationship between unit cell type and porosity and the fatigue behavior of selective laser melted meta-biomaterials","volume":"43","author":"Yavari","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0042","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijfatigue.2015.11.017","article-title":"Computational prediction of the fatigue behavior of additively manufactured porous metallic biomaterials","volume":"84","author":"Hedayati","year":"2016","journal-title":"Int. J. Fatigue"},{"key":"10.1016\/j.actbio.2023.08.040_bib0043","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.actbio.2021.11.002","article-title":"Mechanisms of fatigue crack initiation and propagation in auxetic meta-biomaterials","volume":"138","author":"Kolken","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0044","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/j.msec.2017.02.094","article-title":"Metallic powder-bed based 3D printing of cellular scaffolds for orthopaedic implants: a state-of-the-art review on manufacturing, topological design, mechanical properties and biocompatibility","volume":"76","author":"Tan","year":"2017","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.actbio.2023.08.040_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2022.112651","article-title":"The contribution of pore size and porosity of 3D printed porous titanium scaffolds to osteogenesis","volume":"133","author":"Zhang","year":"2022","journal-title":"Biomater. Adv."},{"issue":"7","key":"10.1016\/j.actbio.2023.08.040_bib0046","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1016\/j.actbio.2012.04.001","article-title":"The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser-melted Ti6Al4V bone scaffolds","volume":"8","author":"Van Bael","year":"2012","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0047","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1038\/s41467-023-36436-w","article-title":"Emergent collective organization of bone cells in complex curvature fields","volume":"14","author":"Callens","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.actbio.2023.08.040_bib0048","article-title":"Effect of mechanical loading on osseointegration combined with degradation behavior of magnesium bone screw in vivo","volume":"32","author":"Gao","year":"2023","journal-title":"Appl. Mater. Today"},{"key":"10.1016\/j.actbio.2023.08.040_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2019.110406","article-title":"Effects of immediately static loading on osteointegration and osteogenesis around 3D-printed porous implant: a histological and biomechanical study","volume":"108","author":"Yu","year":"2020","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.actbio.2023.08.040_bib0050","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/853289","article-title":"The effect of negative Poisson's ratio polyurethane scaffolds for articular cartilage tissue engineering applications","volume":"2013","author":"Park","year":"2013","journal-title":"Adv. Mater. Sci. Eng."},{"key":"10.1016\/j.actbio.2023.08.040_bib0051","first-page":"302","article-title":"MG-63 cells proliferation following various types of mechanical stimulation on cells by auxetic hybrid scaffolds","volume":"20","author":"Choi","year":"2016","journal-title":"Biomater. Res."},{"key":"10.1016\/j.actbio.2023.08.040_bib0052","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1286109","article-title":"MG-63 cell proliferation with static or dynamic compressive stimulation on an auxetic PLGA scaffold","volume":"2017","author":"Kim","year":"2017","journal-title":"Int. J. Polym. Sci."},{"key":"10.1016\/j.actbio.2023.08.040_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2020.108982","article-title":"Cyclic tensile stimulation enrichment of Schwann cell-laden auxetic hydrogel scaffolds towards peripheral nerve tissue engineering","volume":"195","author":"Chen","year":"2020","journal-title":"Mater. Des."},{"key":"10.1016\/j.actbio.2023.08.040_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.euromechsol.2022.104905","article-title":"Auxetic metamaterials for bone-implanted medical devices: recent advances and new perspectives","volume":"98","author":"Shirzad","year":"2023","journal-title":"Eur. J. Mech. A Solids"},{"key":"10.1016\/j.actbio.2023.08.040_bib0055","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.actbio.2018.11.019","article-title":"Effect of stress on corrosion of high-purity magnesium in vitro and in vivo","volume":"83","author":"Gao","year":"2019","journal-title":"Acta Biomater."},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0056","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s10409-021-01116-9","article-title":"Biomechanical study on implantable and interventional medical devices","volume":"37","author":"Wang","year":"2021","journal-title":"Acta Mech. Sin."},{"key":"10.1016\/j.actbio.2023.08.040_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2022.105409","article-title":"Mechanical performance of additively manufactured cobalt-chromium-molybdenum auxetic meta-biomaterial bone scaffolds","volume":"134","author":"Wanniarachchi","year":"2022","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"3","key":"10.1016\/j.actbio.2023.08.040_bib0058","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s10616-015-9895-4","article-title":"Scaffolds and cells for tissue regeneration: different scaffold pore sizes-different cell effects","volume":"68","author":"Bruzauskaite","year":"2016","journal-title":"Cytotechnology"},{"key":"10.1016\/j.actbio.2023.08.040_bib0059","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.msec.2015.10.069","article-title":"Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: an in vivo experiment","volume":"59","author":"Taniguchi","year":"2016","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.actbio.2023.08.040_bib0060","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jallcom.2017.05.079","article-title":"Analysis of factors influencing bone ingrowth into three-dimensional printed porous metal scaffolds: a review","volume":"717","author":"Wang","year":"2017","journal-title":"J. Alloy. Compd."},{"key":"10.1016\/j.actbio.2023.08.040_bib0061","doi-asserted-by":"crossref","first-page":"19468","DOI":"10.1038\/srep19468","article-title":"Design and fabrication of 3D printed scaffolds with a mechanical strength comparable to cortical bone to repair large bone defects","volume":"6","author":"Roohani-Esfahani","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2023.08.040_bib0062","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jmbbm.2016.02.036","article-title":"Influence of the overall stiffness of a load-bearing porous titanium implant on bone ingrowth in critical-size mandibular bone defects in sheep","volume":"59","author":"Schouman","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0063","series-title":"Standard Specification and Test Methods for Metallic Medical Bone Screws","first-page":"1","year":"2017"},{"key":"10.1016\/j.actbio.2023.08.040_bib0064","first-page":"1","volume":"1099","year":"2017"},{"key":"10.1016\/j.actbio.2023.08.040_bib0065","series-title":"Metallic materials\u2013Tensile testing\u2013Part 1: Method of Test at Room Temperature","first-page":"1","year":"2019"},{"issue":"3","key":"10.1016\/j.actbio.2023.08.040_bib0066","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.actamat.2011.10.051","article-title":"Compression fatigue behavior of Ti6Al4V mesh arrays fabricated by electron beam melting","volume":"60","author":"Li","year":"2012","journal-title":"Acta Mater."},{"issue":"5","key":"10.1016\/j.actbio.2023.08.040_bib0067","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/jor.22293","article-title":"Selective laser melting-produced porous titanium scaffolds regenerate bone in critical size cortical bone defects","volume":"31","author":"Van der Stok","year":"2013","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.actbio.2023.08.040_bib0068","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.actbio.2017.02.024","article-title":"Additively manufactured metallic porous biomaterials based on minimal surfaces: A unique combination of topological, mechanical, and mass transport properties","volume":"53","author":"Bobbert","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0069","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.msec.2017.03.091","article-title":"Fatigue crack propagation in additively manufactured porous biomaterials","volume":"76","author":"Hedayati","year":"2017","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.actbio.2023.08.040_bib0070","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.actbio.2016.10.005","article-title":"Improving the fatigue performance of porous metallic biomaterials produced by selective laser melting","volume":"47","author":"van Hooreweder","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0071","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actamat.2018.02.060","article-title":"Compressive and fatigue behavior of functionally graded Ti-6Al-4V meshes fabricated by electron beam melting","volume":"150","author":"Zhao","year":"2018","journal-title":"Acta Mater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0072","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.actamat.2019.09.042","article-title":"Compression\u2013compression fatigue behaviour of gyroid-type triply periodic minimal surface porous structures fabricated by selective laser melting","volume":"181","author":"Yang","year":"2019","journal-title":"Acta Mater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0073","series-title":"Proceedings of the 10th International Conference on Key Engineering Materials (ICKEM)","first-page":"1979","article-title":"Low-cycle fatigue behavior of 3D-printed metallic auxetic structure","author":"Lvov","year":"2020"},{"key":"10.1016\/j.actbio.2023.08.040_bib0074","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.actbio.2021.03.015","article-title":"Fatigue performance of auxetic meta-biomaterials","volume":"126","author":"Kolken","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0075","article-title":"Fatigue properties of Ti-6Al-4V Gyroid graded lattice structures fabricated by laser powder bed fusion with lateral loading","volume":"46","author":"Yang","year":"2021","journal-title":"Addit. Manuf."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0076","doi-asserted-by":"crossref","first-page":"4957","DOI":"10.1038\/s41598-018-23414-2","article-title":"Fatigue life of additively manufactured Ti6Al4V scaffolds under tension-tension, tension-compression and compression-compression fatigue load","volume":"8","author":"Lietaert","year":"2018","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0077","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.injury.2008.10.035","article-title":"The influence of osteoporosis in femoral fracture healing time","volume":"40","author":"Nikolaou","year":"2009","journal-title":"Injury"},{"issue":"18","key":"10.1016\/j.actbio.2023.08.040_bib0078","doi-asserted-by":"crossref","first-page":"7060","DOI":"10.1016\/j.actamat.2011.07.061","article-title":"Enhanced fatigue properties of nanostructured austenitic SUS 316L stainless steel","volume":"59","author":"Ueno","year":"2011","journal-title":"Acta Mater."},{"key":"10.1016\/j.actbio.2023.08.040_bib0079","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/j.clinbiomech.2007.12.011","article-title":"Comparative evaluation on three-dimensional finite element models of the temporomandibular joint","volume":"23","author":"Liu","year":"2008","journal-title":"Clin. Biomech."},{"issue":"9","key":"10.1016\/j.actbio.2023.08.040_bib0080","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1111\/j.1365-2842.2001.00763.x","article-title":"Influences of occlusal and skeletal discrepancies on biomechanical environment in the TMJ during maximum clenching: an analytic approach with the finite element method","volume":"28","author":"Tanaka","year":"2001","journal-title":"J. Oral Rehabil."},{"key":"10.1016\/j.actbio.2023.08.040_bib0081","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.msea.2017.01.056","article-title":"Plastic analyses of thin-walled steel honeycombs with re-entrant deformation style","volume":"688","author":"Zhou","year":"2017","journal-title":"Mater. Sci. Eng. A"},{"key":"10.1016\/j.actbio.2023.08.040_bib0082","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.matdes.2017.11.037","article-title":"Additively-manufactured lightweight Metamaterials for energy absorption","volume":"139","author":"Mohsenizadeh","year":"2018","journal-title":"Mater. Des."},{"issue":"5","key":"10.1016\/j.actbio.2023.08.040_bib0083","doi-asserted-by":"crossref","DOI":"10.1088\/1361-665X\/ac6291","article-title":"Reversible energy absorption of elasto-plastic auxetic, hexagonal, and AuxHex structures fabricated by FDM 4D printing","volume":"31","author":"Namvar","year":"2022","journal-title":"Smart Mater. Struct."},{"key":"10.1016\/j.actbio.2023.08.040_bib0084","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jmps.2017.02.002","article-title":"Tensile response of elastoplastic lattices at finite strain","volume":"109","author":"Tankasala","year":"2017","journal-title":"J. Mech. Phys. Solids"},{"key":"10.1016\/j.actbio.2023.08.040_bib0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.compositesb.2020.108340","article-title":"Large deformation and energy absorption of additively manufactured auxetic materials and structures: a review","volume":"201","author":"Zhang","year":"2020","journal-title":"Compos. Part B Eng."},{"key":"10.1016\/j.actbio.2023.08.040_bib0086","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1016\/j.matpr.2020.06.130","article-title":"Low-cycle fatigue behavior of 3D-printed metallic auxetic structure","volume":"33","author":"Lvov","year":"2020","journal-title":"Mater. Today Proc."},{"key":"10.1016\/j.actbio.2023.08.040_bib0087","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmecsci.2021.106432","article-title":"Enhanced fatigue performance of auxetic honeycomb\/substrate structures under thermal cycling","volume":"199","author":"Hu","year":"2021","journal-title":"Int. J. Mech. Sci."},{"key":"10.1016\/j.actbio.2023.08.040_bib0088","series-title":"Proceedings of the 23rd Annual International Solid Freeform Fabrication Symposium - An Additive Manufacturing Conference, SFF","article-title":"Effect of defects on fatigue tests of as-built TI-6AL-4V parts fabricated by selective laser melting","author":"Gong","year":"2012"},{"key":"10.1016\/j.actbio.2023.08.040_bib0089","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijfatigue.2019.01.013","article-title":"Effect of post-treatments on the fatigue behaviour of 316L stainless steel manufactured by laser powder bed fusion","volume":"123","author":"Elangeswaran","year":"2019","journal-title":"Int. J. Fatigue"},{"key":"10.1016\/j.actbio.2023.08.040_bib0090","series-title":"Fracture Mechanics","first-page":"7","article-title":"Linear elastic stress analysis of 2D cracks","author":"Zehnder","year":"2012"},{"key":"10.1016\/j.actbio.2023.08.040_bib0091","article-title":"Mixed-mode fracture behaviors of AISI 1045 and AISI 5140 steels in compressor crankshafts - Part I: mode I-III","volume":"110","author":"Nie","year":"2020","journal-title":"Eng. Fail. Anal."},{"key":"10.1016\/j.actbio.2023.08.040_bib0092","article-title":"Mixed-mode fracture behaviors of AISI 1045 and AISI 5140 steels in compressor crankshafts - Part II: mode II-III","volume":"110","author":"Nie","year":"2020","journal-title":"Eng. Fail. Anal."},{"issue":"3","key":"10.1016\/j.actbio.2023.08.040_bib0093","doi-asserted-by":"crossref","first-page":"603","DOI":"10.3390\/nano11030603","article-title":"Nanocellulose\/PEGDA aerogels with tunable Poisson's ratio fabricated by stereolithography for mouse bone marrow mesenchymal stem cell culture","volume":"11","author":"Tang","year":"2021","journal-title":"Nanomaterials"},{"issue":"4","key":"10.1016\/j.actbio.2023.08.040_bib0094","first-page":"294","article-title":"MG-63 osteoblast-like cell proliferation on auxetic PLGA scaffold with mechanical stimulation for bone tissue regeneration","volume":"20","author":"Choi","year":"2016","journal-title":"Biomater. Res."},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0095","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3390\/bioengineering10020204","article-title":"A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges","volume":"10","author":"Abdelaziz","year":"2023","journal-title":"Bioengineering"},{"key":"10.1016\/j.actbio.2023.08.040_bib0096","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1016\/j.jmrt.2023.01.155","article-title":"Research progress on the design and performance of porous titanium alloy bone implants","volume":"23","author":"Song","year":"2023","journal-title":"J. Mater. Res. Technol."},{"issue":"45","key":"10.1016\/j.actbio.2023.08.040_bib0097","doi-asserted-by":"crossref","first-page":"39235","DOI":"10.1021\/acsami.7b13960","article-title":"Influence of porosity and pore-size distribution in Ti6Al4 V foam on physicomechanical properties, osteogenesis, and quantitative validation of bone ingrowth by micro-computed tomography","volume":"9","author":"Kapat","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2023.08.040_bib0098","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jmbbm.2015.06.024","article-title":"Ti-6Al-4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting","volume":"51","author":"Yan","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"6","key":"10.1016\/j.actbio.2023.08.040_bib0099","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.bone.2005.11.026","article-title":"Cancellous bone adaptation to in vivo loading in a rabbit model","volume":"38","author":"van der Meulen","year":"2006","journal-title":"Bone"},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0100","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/jor.23758","article-title":"Bone remodeling and mechanobiology around implants: insights from small animal imaging","volume":"36","author":"Li","year":"2018","journal-title":"J. Orthop. Res."},{"issue":"10","key":"10.1016\/j.actbio.2023.08.040_bib0101","first-page":"3097","article-title":"Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration","volume":"6","author":"Zhang","year":"2021","journal-title":"Bioact. Mater."},{"issue":"13","key":"10.1016\/j.actbio.2023.08.040_bib0102","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.3390\/cells11132069","article-title":"The synergistic effect of cyclic tensile force and periodontal ligament cell-laden calcium silicate\/gelatin methacrylate auxetic hydrogel scaffolds for bone regeneration","volume":"11","author":"Lee","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.actbio.2023.08.040_bib0103","series-title":"Proceedings of the IEEE 22nd International Conference on Bioinformatics and Bioengineering (BIBE)","first-page":"117","article-title":"The effect of tensile force and periodontal ligament cell-laden calcium silicate\/bioinks auxetic scaffolds for tissue engineering","author":"Lin","year":"2022"},{"key":"10.1016\/j.actbio.2023.08.040_bib0104","doi-asserted-by":"crossref","DOI":"10.3389\/fsurg.2020.601244","article-title":"Bone and cartilage interfaces with orthopedic implants: a literature review","volume":"7","author":"Grzeskowiak","year":"2020","journal-title":"Front. Surg."},{"issue":"11","key":"10.1016\/j.actbio.2023.08.040_bib0105","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1111\/clr.12756","article-title":"Validation of value of actual micromotion as a direct measure of implant micromobility after healing (secondary implant stability). an in vivo histologic and biomechanical study","volume":"27","author":"Trisi","year":"2016","journal-title":"Clin. Oral Implants Res."},{"issue":"7","key":"10.1016\/j.actbio.2023.08.040_bib0106","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1002\/jbm.a.34510","article-title":"Immediate post-implantation skin immobilization decreases skin regression around percutaneous osseointegrated prosthetic implant systems","volume":"101","author":"Holt","year":"2013","journal-title":"J. Biomed. Mater. Res. Part A"},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0107","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00167-006-0118-6","article-title":"Comparison of direct and indirect interference screw fixation for tendon graft in rabbits","volume":"15","author":"Tomihara","year":"2007","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"issue":"8","key":"10.1016\/j.actbio.2023.08.040_bib0108","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.arthro.2009.12.022","article-title":"The effect of interference screw diameter on fixation of soft-tissue grafts in anterior cruciate ligament reconstruction","volume":"26","author":"Micucci","year":"2010","journal-title":"Arthrosc. J. Arthrosc. Relat. Surg."},{"key":"10.1016\/j.actbio.2023.08.040_bib0109","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jmbbm.2013.01.017","article-title":"Micromotion and friction evaluation of a novel surface architecture for improved primary fixation of cementless orthopaedic implants","volume":"21","author":"Harrison","year":"2013","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0110","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/jbm.b.31198","article-title":"Porous tantalum in hip and knee reconstructive surgery","volume":"89B","author":"Patil","year":"2009","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"issue":"12","key":"10.1016\/j.actbio.2023.08.040_bib0111","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.2106\/00004623-199312000-00009","article-title":"Tendon-healing in a bone tunnel. A biomechanical and histological study in the dog","volume":"75","author":"Rodeo","year":"1993","journal-title":"J. Bone Jt. Surg. Am."},{"key":"10.1016\/j.actbio.2023.08.040_bib0112","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00003086-198301000-00016","article-title":"Vascularized patellar tendon graft with rigid internal fixation for anterior cruciate ligament insufficiency","volume":"172","author":"Lambert","year":"1983","journal-title":"Clin. Orthop. Relat. Res."},{"issue":"2","key":"10.1016\/j.actbio.2023.08.040_bib0113","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1177\/0363546503261703","article-title":"Interference screw fixation of soft tissue grafts in anterior cruciate ligament reconstruction: part 2: effect of preconditioning on graft tension during and after screw insertion","volume":"32","author":"Nurmi","year":"2004","journal-title":"Am. J. Sports Med."},{"issue":"14","key":"10.1016\/j.actbio.2023.08.040_bib0114","doi-asserted-by":"crossref","first-page":"3825","DOI":"10.1177\/03635465211047861","article-title":"A higher initial tensioning force of an ACL graft results in a higher graft force after screw fixation irrespective of the screw diameter: a biomechanical study","volume":"49","author":"Kayaalp","year":"2021","journal-title":"Am. J. Sports Med."},{"issue":"5","key":"10.1016\/j.actbio.2023.08.040_bib0115","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1249\/MSS.0000000000002860","article-title":"Linking gait biomechanics and daily steps after ACL reconstruction","volume":"54","author":"Lisee","year":"2022","journal-title":"Med. Sci. Sports Exerc."},{"issue":"1","key":"10.1016\/j.actbio.2023.08.040_bib0116","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12893-022-01685-x","article-title":"A prospective comparison of 3 hamstring ACL fixation devices\u2014rigidfix, bioscrew, and intrafix\u2014randomized into 4 groups with a minimum follow-up of 5 years","volume":"22","author":"Metso","year":"2022","journal-title":"BMC Surg."},{"issue":"11","key":"10.1016\/j.actbio.2023.08.040_bib0117","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.1007\/s00586-017-5062-2","article-title":"Osseointegration improves bone-implant interface of pedicle screws in the growing spine: a biomechanical and histological study using an in vivo immature porcine model","volume":"26","author":"Shiba","year":"2017","journal-title":"Eur. Spine J."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706123005044?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706123005044?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:10:07Z","timestamp":1761675007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706123005044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":117,"alternative-id":["S1742706123005044"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2023.08.040","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vitro fatigue behavior and in vivo osseointegration of the auxetic porous bone screw","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2023.08.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}