{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:30:12Z","timestamp":1790436612511,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["21623410"],"award-info":[{"award-number":["21623410"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102113"],"award-info":[{"award-number":["82102113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.actbio.2024.05.026","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T11:49:56Z","timestamp":1715773796000},"page":"171-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["High molecular weight hyaluronic acid-liposome delivery system for efficient transdermal treatment of acute and chronic skin photodamage"],"prefix":"10.1016","volume":"182","author":[{"given":"Hui","family":"Xing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangjun","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4962-2754","authenticated-orcid":false,"given":"Yihan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanqi","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guowei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1814-7348","authenticated-orcid":false,"given":"Dong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2024.05.026_bib0001","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3389\/fphar.2019.00759","article-title":"Environmental stressors on skin aging. Mechanistic insights","volume":"10","author":"Parrado","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"10","key":"10.1016\/j.actbio.2024.05.026_bib0002","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1111\/jdv.17432","article-title":"Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors","volume":"35","author":"Passeron","year":"2021","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"5","key":"10.1016\/j.actbio.2024.05.026_bib0003","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1586\/17469872.2013.836845","article-title":"Minimally invasive facial rejuvenation: current concepts and future expectations","volume":"8","author":"El-Domyati","year":"2013","journal-title":"Expert Rev. Dermatol."},{"issue":"6","key":"10.1016\/j.actbio.2024.05.026_bib0004","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.3390\/pharmaceutics14061152","article-title":"Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems","volume":"14","author":"Alkilani","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.actbio.2024.05.026_bib0005","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.colsurfb.2018.08.061","article-title":"Hyaluronic acid-containing ethosomes as a potential carrier for transdermal drug delivery","volume":"172","author":"Xie","year":"2018","journal-title":"Colloids Surf. B"},{"key":"10.1016\/j.actbio.2024.05.026_bib0006","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.actbio.2016.06.005","article-title":"Rapidly separating microneedles for transdermal drug delivery","volume":"41","author":"Zhu","year":"2016","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.actbio.2024.05.026_bib0007","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40824-021-00226-6","article-title":"Recent advances in transdermal drug delivery systems: a review","volume":"25","author":"Jeong","year":"2021","journal-title":"Biomater. Res."},{"key":"10.1016\/j.actbio.2024.05.026_bib0008","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/B978-0-12-800269-8.00009-9","article-title":"Beneficial effects of hyaluronic acid","volume":"72","author":"Sudha","year":"2014","journal-title":"Adv. Food Nutr. Res."},{"issue":"6","key":"10.1016\/j.actbio.2024.05.026_bib0009","doi-asserted-by":"crossref","first-page":"743","DOI":"10.2217\/nnm.14.47","article-title":"Enhancing the transdermal penetration of nanoconstructs: could hyaluronic acid be the key?","volume":"9","author":"Jung","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.actbio.2024.05.026_bib0010","series-title":"Functional Polysaccharides for Biomedical Applications","first-page":"213","article-title":"Hyaluronic acid as potential carrier in biomedical and drug delivery applications","author":"Prajapati","year":"2019"},{"issue":"15","key":"10.1016\/j.actbio.2024.05.026_bib0011","doi-asserted-by":"crossref","first-page":"4429","DOI":"10.3390\/molecules26154429","article-title":"Advantages of hyaluronic acid and its combination with other bioactive ingredients in cosmeceuticals","volume":"26","author":"Juncan","year":"2021","journal-title":"Molecules"},{"issue":"11","key":"10.1016\/j.actbio.2024.05.026_bib0012","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.3390\/molecules25112649","article-title":"Hyaluronic acid and controlled release: a review","volume":"25","author":"Bayer","year":"2020","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.actbio.2024.05.026_bib0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-020-03577-8","article-title":"Efficacy of single high-molecular-weight versus triple low-molecular-weight hyaluronic acid intra-articular injection among knee osteoarthritis patients","volume":"21","author":"Bahrami","year":"2020","journal-title":"BMC Musculoskelet Disord."},{"key":"10.1016\/j.actbio.2024.05.026_bib0014","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s40005-016-0260-1","article-title":"Liposomal drug delivery system","volume":"46","author":"Kim","year":"2016","journal-title":"J. Pharm. Investig."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0015","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4155\/tde-2020-0122","article-title":"Liposomes and transferosomes: a breakthrough in topical and transdermal delivery","volume":"12","author":"Sapkota","year":"2021","journal-title":"Ther. Deliv."},{"issue":"10","key":"10.1016\/j.actbio.2024.05.026_bib0016","doi-asserted-by":"crossref","DOI":"10.1002\/admt.202101615","article-title":"A comprehensive review of one decade of microfluidic platforms applications in synthesis of enhanced carriers utilized in controlled drug delivery","volume":"7","author":"Siavashy","year":"2022","journal-title":"Adv. Mater. Technol."},{"issue":"3","key":"10.1016\/j.actbio.2024.05.026_bib0017","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3390\/pharmaceutics14030543","article-title":"Methods of liposomes preparation: formation and control factors of versatile nanocarriers for biomedical and nanomedicine application","volume":"14","author":"Lombardo","year":"2022","journal-title":"Pharmaceutics"},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0018","first-page":"229","article-title":"Controllable synthesis of polymeric micelles by microfluidic platforms for biomedical applications: a systematic review","volume":"20","author":"Ahmadi","year":"2021","journal-title":"Iran. J. Pharm. Res."},{"key":"10.1016\/j.actbio.2024.05.026_bib0019","article-title":"Transdermal sustained release properties and anti-photoaging efficacy of liposome-thermosensitive hydrogel system","author":"Wu","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2024.05.026_bib0020","first-page":"190","article-title":"Nitric oxide synergizes minoxidil delivered by transdermal hyaluronic acid liposomes for multimodal androgenetic-alopecia therapy","volume":"32","author":"Xing","year":"2024","journal-title":"Bioact. Mater."},{"issue":"5","key":"10.1016\/j.actbio.2024.05.026_bib0021","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1021\/am300375m","article-title":"Functional polysaccharide conjugates for the preparation of microarrays","volume":"4","author":"Mohan","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2024.05.026_bib0022","first-page":"1","article-title":"Franz diffusion cell and its implication in skin permeation studies","author":"Kumar","year":"2023","journal-title":"J. Dispers. Sci. Technol."},{"issue":"11","key":"10.1016\/j.actbio.2024.05.026_bib0023","first-page":"398","article-title":"Visualization and quantification of penetration\/mass transfer of acrylic resin retanning agent in leather using florescent tracing technique","volume":"111","author":"Zeng","year":"2016","journal-title":"J. Am. Leather Chem. Assoc."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0024","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.foodres.2007.11.001","article-title":"Encapsulation in alginate-coated gelatin microspheres improves survival of the probiotic Bifidobacterium adolescentis 15703T during exposure to simulated gastro-intestinal conditions","volume":"41","author":"Annan","year":"2008","journal-title":"Food Res. Int."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0025","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/jfb5020043","article-title":"HaCaT keratinocytes response on antimicrobial atelocollagen substrates: extent of cytotoxicity, cell viability and proliferation","volume":"5","author":"L\u00f3pez-Garc\u00eda","year":"2014","journal-title":"J. Funct. Biomater."},{"key":"10.1016\/j.actbio.2024.05.026_bib0026","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.actbio.2022.11.006","article-title":"Dynamic nitric oxide\/drug codelivery system based on polyrotaxane architecture for effective treatment of Candida albicans infection","volume":"155","author":"Li","year":"2023","journal-title":"Acta Biomater."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0027","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nprot.2007.30","article-title":"In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro","volume":"2","author":"Liang","year":"2007","journal-title":"Nat. Protoc."},{"issue":"46","key":"10.1016\/j.actbio.2024.05.026_bib0028","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202303580","article-title":"A transdermal drug delivery system based on nucleic acid nanomaterials for skin photodamage treatment","volume":"33","author":"Xie","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.actbio.2024.05.026_bib0029","series-title":"Enzyme linked Immunosorbent Assay","author":"Alhajj","year":"2023"},{"key":"10.1016\/j.actbio.2024.05.026_bib0030","series-title":"Molecular Mechanism of PUVA-induced Apoptosis in Mouse Epidermal Cells","author":"Santamaria","year":"2001"},{"key":"10.1016\/j.actbio.2024.05.026_bib0031","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3389\/fphar.2016.00301","article-title":"Protective effect of cyanidin-3-O-glucoside against ultraviolet B radiation-induced cell damage in human HaCaT keratinocytes","volume":"7","author":"Hu","year":"2016","journal-title":"Front. Pharmacol."},{"issue":"10","key":"10.1016\/j.actbio.2024.05.026_bib0032","doi-asserted-by":"crossref","first-page":"11273","DOI":"10.1021\/acsnano.9b04384","article-title":"Needle-free injection of exosomes derived from human dermal fibroblast spheroids ameliorates skin photoaging","volume":"13","author":"Hu","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2024.05.026_bib0033","first-page":"368","article-title":"Anti-inflammatory activity of curcumin-loaded tetrahedral framework nucleic acids on acute gouty arthritis","volume":"8","author":"Zhang","year":"2022","journal-title":"Bioact. Mater."},{"issue":"1\u20132","key":"10.1016\/j.actbio.2024.05.026_bib0034","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0378-5173(03)00183-2","article-title":"Particle size of liposomes influences dermal delivery of substances into skin","volume":"258","author":"Verma","year":"2003","journal-title":"Int. J. Pharm."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0035","doi-asserted-by":"crossref","first-page":"150","DOI":"10.34172\/apb.2020.021","article-title":"Nanostructured lipid carriers: a groundbreaking approach for transdermal drug delivery","volume":"10","author":"Chauhan","year":"2020","journal-title":"Adv. Pharm. Bull."},{"issue":"2","key":"10.1016\/j.actbio.2024.05.026_bib0036","first-page":"255","article-title":"Effect of zeta potential on the properties of nano-drug delivery systems-a review (Part 1)","volume":"12","author":"Honary","year":"2013","journal-title":"Trop. J. Pharm. Res."},{"issue":"8","key":"10.1016\/j.actbio.2024.05.026_bib0037","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.3390\/polym12081800","article-title":"Hyaluronic acid: the influence of molecular weight on structural, physical, physico-chemical, and degradable properties of biopolymer","volume":"12","author":"Snetkov","year":"2020","journal-title":"Polymers"},{"key":"10.1016\/j.actbio.2024.05.026_bib0038","first-page":"117","article-title":"Particle size distribution and zeta potential based on dynamic light scattering: techniques to characterize stability and surface charge distribution of charged colloids","volume":"28","author":"Karmakar","year":"2019","journal-title":"Recent Trends Mater. Phys. Chem"},{"key":"10.1016\/j.actbio.2024.05.026_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.113851","article-title":"Liposome composition in drug delivery design, synthesis, characterization, and clinical application","volume":"176","author":"Large","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"11","key":"10.1016\/j.actbio.2024.05.026_bib0040","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/nbt.1504","article-title":"Transdermal drug delivery","volume":"26","author":"Prausnitz","year":"2008","journal-title":"Nat. Biotechnol."},{"issue":"1","key":"10.1016\/j.actbio.2024.05.026_bib0041","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jtcme.2017.06.012","article-title":"In vitro anti-inflammatory and skin protective properties of Virgin coconut oil","volume":"9","author":"Varma","year":"2019","journal-title":"J. Tradit. Complement. Med."},{"issue":"4","key":"10.1016\/j.actbio.2024.05.026_bib0042","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3390\/ph14040301","article-title":"Wound healing promotion by hyaluronic acid: effect of molecular weight on gene expression and in vivo wound closure","volume":"14","author":"Kawano","year":"2021","journal-title":"Pharmaceuticals"},{"issue":"8","key":"10.1016\/j.actbio.2024.05.026_bib0043","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3390\/nu8080464","article-title":"Protective effect of garlic on cellular senescence in UVB-exposed HaCaT human keratinocytes","volume":"8","author":"Kim","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.actbio.2024.05.026_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.123717","article-title":"Succinoglycan riclin relieves UVB-induced skin injury with anti-oxidant and anti-inflammatory properties","volume":"235","author":"Lu","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"issue":"22","key":"10.1016\/j.actbio.2024.05.026_bib0045","doi-asserted-by":"crossref","first-page":"8790","DOI":"10.3390\/ijms21228790","article-title":"The immune functions of keratinocytes in skin wound healing","volume":"21","author":"Piipponen","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.actbio.2024.05.026_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.545008","article-title":"Effects of IL-1\u03b2 and TNF-\u03b1 on the expression of P311 in vascular endothelial cells and wound healing in mice","volume":"11","author":"Zhou","year":"2020","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.actbio.2024.05.026_bib0047","article-title":"Role of collagen in wound healing","volume":"13","author":"Harsha","year":"2020","journal-title":"Drug Invent. Today"},{"key":"10.1016\/j.actbio.2024.05.026_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.126530","article-title":"Sodium alginate\/poly (vinyl alcohol)\/taxifolin nanofiber mat promoting diabetic wound healing by modulating the inflammatory response, angiogenesis, and skin flora","volume":"252","author":"Wang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2024.05.026_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111247","article-title":"Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia","volume":"137","author":"Fu","year":"2021","journal-title":"Biomed. Pharmacother."}],"updated-by":[{"DOI":"10.1016\/j.actbio.2025.10.065","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000}},{"DOI":"10.1016\/j.actbio.2025.10.065","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000}}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124002654?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124002654?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T08:09:27Z","timestamp":1774080567000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706124002654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":49,"alternative-id":["S1742706124002654"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2024.05.026","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High molecular weight hyaluronic acid-liposome delivery system for efficient transdermal treatment of acute and chronic skin photodamage","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2024.05.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Acta Materialia Inc. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}