{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T22:22:08Z","timestamp":1787782928337,"version":"build-2784847793"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007053","name":"Korea Institute of Energy Technology Evaluation and Planning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korea Ministry of Science and ICT","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.actbio.2024.09.019","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T09:15:55Z","timestamp":1726650955000},"page":"212-222","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Latent stem cell-stimulating radially aligned electrospun nanofibrous patches for chronic tympanic membrane perforation therapy"],"prefix":"10.1016","volume":"188","author":[{"given":"Juo","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0559-4840","authenticated-orcid":false,"given":"Sangbae","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beomyong","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon Ju","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungmin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungsil","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung-Je","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oak-Sung","family":"Choo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jangho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1827-9359","authenticated-orcid":false,"given":"Hoon","family":"Seonwoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0711-5655","authenticated-orcid":false,"given":"Jong Hoon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Hoon","family":"Choung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0001","first-page":"10","article-title":"Repair of chronic tympanic membrane perforations using epidermal growth factor: progress toward clinical application","volume":"15","author":"Lee","year":"1994","journal-title":"Otol. Neurotol."},{"issue":"5","key":"10.1016\/j.actbio.2024.09.019_bib0002","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1097\/MLG.0b013e318038168a","article-title":"Bilateral myringoplasty in chronic otitis media","volume":"117","author":"Caye-Thomasen","year":"2007","journal-title":"Laryngoscope"},{"key":"10.1016\/j.actbio.2024.09.019_bib0003","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ijbiomac.2013.08.049","article-title":"Regeneration of chronic tympanic membrane perforation using 3D collagen with topical umbilical cord serum","volume":"62","author":"Jang","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0004","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijporl.2012.09.022","article-title":"Repair of tympanic membrane perforation using novel adjuvant therapies: a contemporary review of experimental and tissue engineering studies","volume":"77","author":"Hong","year":"2013","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"issue":"6","key":"10.1016\/j.actbio.2024.09.019_bib0005","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/coa.12017","article-title":"Impact of basic fibroblast growth factor on healing of tympanic membrane perforations due to direct penetrating trauma: a prospective non-blinded\/controlled study","volume":"37","author":"Zhang","year":"2012","journal-title":"Clin. Otolaryngol."},{"key":"10.1016\/j.actbio.2024.09.019_bib0006","series-title":"Wound healing: a Paradigm For Regeneration","first-page":"1022","author":"Wong","year":"2013"},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0007","first-page":"141","article-title":"Efficient treatment of chronic tympanic membrane perforations in animal models by chitosan patch scaffolds","volume":"8","author":"Choi","year":"2011","journal-title":"Tissue Eng. Regen. Med."},{"issue":"3","key":"10.1016\/j.actbio.2024.09.019_bib0008","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0196-0709(00)85017-6","article-title":"Effects of platelet-derived growth factor-AA on the healing process of tympanic membrane perforation","volume":"21","author":"Yeo","year":"2000","journal-title":"Am. J. Otolaryngol."},{"issue":"9","key":"10.1016\/j.actbio.2024.09.019_bib0009","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1288\/00005537-199409000-00002","article-title":"Evaluation of basic fibroblast growth factor in tympanic membrane repair","volume":"104","author":"Vrabec","year":"1994","journal-title":"Laryngoscope"},{"issue":"8","key":"10.1016\/j.actbio.2024.09.019_bib0010","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/j.ijporl.2015.05.020","article-title":"Searching for a rat model of chronic tympanic membrane perforation: healing delayed by mitomycin C\/dexamethasone but not paper implantation or iterative myringotomy","volume":"79","author":"Wang","year":"2015","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"issue":"5","key":"10.1016\/j.actbio.2024.09.019_bib0011","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1097\/01.mlg.0000208549.44462.fa","article-title":"Tissue-engineered calcium alginate patches in the repair of chronic chinchilla tympanic membrane perforations","volume":"116","author":"Weber","year":"2006","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0012","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201801160","article-title":"Epidermal growth factor\u2013releasing radially aligned electrospun nanofibrous patches for the regeneration of chronic tympanic membrane perforations","volume":"8","author":"Seonwoo","year":"2019","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2024.09.019_bib0013","doi-asserted-by":"crossref","unstructured":"H.A. Ramsay, E.J. Heikkonen, P.K. Laurila, Effect of epidermal growth factor on tympanic membranes with chronic perforations: a clinical trial, Otolaryngol.\u2014Head Neck Surg. 113(4) (1995) 375\u2013379.","DOI":"10.1016\/S0194-59989570071-4"},{"issue":"5","key":"10.1016\/j.actbio.2024.09.019_bib0014","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1097\/01.mao.0000226316.04940.f9","article-title":"Healing of subacute tympanic membrane perforations in chinchillas treated with epidermal growth factor and pentoxifylline","volume":"27","author":"Ramalho","year":"2006","journal-title":"Otol. Neurotol."},{"issue":"7","key":"10.1016\/j.actbio.2024.09.019_bib0015","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1097\/MAO.0000000000000795","article-title":"Heparin binding epidermal growth factor-like growth factor heals chronic tympanic membrane perforations with advantage over fibroblast growth factor 2 and epidermal growth factor in an animal model","volume":"36","author":"Santa Maria","year":"2015","journal-title":"Otol. Neurotol."},{"issue":"6","key":"10.1016\/j.actbio.2024.09.019_bib0016","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.tem.2016.03.019","article-title":"Role of IGF binding proteins in regulating metabolism","volume":"27","author":"Clemmons","year":"2016","journal-title":"Trends Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0017","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/ten.tea.2009.0476","article-title":"Tympanic membrane regeneration using a water-soluble chitosan patch","volume":"16","author":"Kim","year":"2010","journal-title":"Tissue Eng. Part A"},{"issue":"5\u20136","key":"10.1016\/j.actbio.2024.09.019_bib0018","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1089\/ten.tea.2017.0246","article-title":"Repair of tympanic membrane perforations with customized bioprinted ear grafts using chinchilla models","volume":"24","author":"Kuo","year":"2018","journal-title":"Tissue Eng. Part A"},{"issue":"8","key":"10.1016\/j.actbio.2024.09.019_bib0019","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1002\/lary.23940","article-title":"Tympanic membrane repair using silk fibroin and acellular collagen scaffolds","volume":"123","author":"Shen","year":"2013","journal-title":"Laryngoscope"},{"issue":"S2","key":"10.1016\/j.actbio.2024.09.019_bib0020","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1017\/S0022215114002333","article-title":"Clinical study of transcanal closure of tympanic membrane perforations using a collagen sponge","volume":"129","author":"Tamae","year":"2015","journal-title":"J. Laryngol. Otol."},{"key":"10.1016\/j.actbio.2024.09.019_bib0021","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.669863","article-title":"Cellulose-based fibrous materials from bacteria to repair tympanic membrane perforations","volume":"9","author":"Azimi","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0022","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/0885328219845082","article-title":"Latent stem cell-stimulating therapy for regeneration of chronic tympanic membrane perforations using IGFBP2-releasing chitosan patch scaffolds","volume":"34","author":"Seonwoo","year":"2019","journal-title":"J. Biomater. Appl."},{"issue":"17\u201318","key":"10.1016\/j.actbio.2024.09.019_bib0023","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1089\/ten.tea.2012.0617","article-title":"Regeneration of chronic tympanic membrane perforation using an EGF-releasing chitosan patch","volume":"19","author":"Seonwoo","year":"2013","journal-title":"Tissue Eng. Part A"},{"issue":"6","key":"10.1016\/j.actbio.2024.09.019_bib0024","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1039\/c0nr00192a","article-title":"Aligned-to-random\u201d nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site","volume":"2","author":"Xie","year":"2010","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0025","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1038\/srep03552","article-title":"Designing nanotopographical density of extracellular matrix for controlled morphology and function of human mesenchymal stem cells","volume":"3","author":"Kim","year":"2013","journal-title":"Sci. Rep."},{"issue":"7\u20138","key":"10.1016\/j.actbio.2024.09.019_bib0026","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1089\/ten.tea.2023.0242","article-title":"Bacterial cellulose electrospun fiber mesh coated with chitin nanofibrils for eardrum repair","volume":"30","author":"Azimi","year":"2024","journal-title":"Tissue Eng. Part A"},{"issue":"9","key":"10.1016\/j.actbio.2024.09.019_bib0027","doi-asserted-by":"crossref","first-page":"5027","DOI":"10.1021\/nn101554u","article-title":"Radially aligned, electrospun nanofibers as dural substitutes for wound closure and tissue regeneration applications","volume":"4","author":"Xie","year":"2010","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0028","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000381877","article-title":"Stem cells in wound healing: the future of regenerative medicine? A mini-review","volume":"62","author":"Duscher","year":"2016","journal-title":"Gerontology"},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0029","article-title":"Stem cell niches for skin regeneration","volume":"2012","author":"Wong","year":"2012","journal-title":"Int. J. Biomater."},{"key":"10.1016\/j.actbio.2024.09.019_bib0030","doi-asserted-by":"crossref","unstructured":"S. Goncalves, E. Bas, B.J. Goldstein, S. Angeli, Effects of cell-based therapy for treating tympanic membrane perforations in mice, Otolaryngol.\u2013Head Neck Surg. 154(6) (2016) 1106\u20131114.","DOI":"10.1177\/0194599816636845"},{"key":"10.1016\/j.actbio.2024.09.019_bib0031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-016-0394-0","article-title":"Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies","volume":"7","author":"Hofer","year":"2016","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.actbio.2024.09.019_bib0032","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.msec.2016.11.094","article-title":"Mesenchymal stem cell-laden hybrid scaffold for regenerating subacute tympanic membrane perforation","volume":"72","author":"Jang","year":"2017","journal-title":"Mater. Sci. Eng.: C"},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0033","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.biomaterials.2011.09.041","article-title":"Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold","volume":"33","author":"Rustad","year":"2012","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0034","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.stem.2007.11.014","article-title":"Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide","volume":"2","author":"Ren","year":"2008","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0035","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1073\/pnas.1413445112","article-title":"Transdermal deferoxamine prevents pressure-induced diabetic ulcers","volume":"112","author":"Duscher","year":"2015","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"11","key":"10.1016\/j.actbio.2024.09.019_bib0036","doi-asserted-by":"crossref","first-page":"3648","DOI":"10.1158\/1078-0432.CCR-08-2276","article-title":"Antimyeloangiogenic\u201d therapy for cancer by inhibiting PlGF","volume":"15","author":"Loges","year":"2009","journal-title":"Clin. Cancer Res."},{"issue":"12","key":"10.1016\/j.actbio.2024.09.019_bib0037","doi-asserted-by":"crossref","first-page":"e51945","DOI":"10.1371\/journal.pone.0051945","article-title":"Role of EC-SOD overexpression in preserving pulmonary angiogenesis inhibited by oxidative stress","volume":"7","author":"Perveen","year":"2012","journal-title":"PLoS One"},{"issue":"24","key":"10.1016\/j.actbio.2024.09.019_bib0038","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1161\/CIRCULATIONAHA.107.715847","article-title":"Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1\u03b1 stabilization during ischemia","volume":"116","author":"Chang","year":"2007","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.actbio.2024.09.019_bib0039","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1524-475X.2007.00251.x","article-title":"Chronic tympanic membrane perforation: a better animal model is needed","volume":"15","author":"Santa Maria","year":"2007","journal-title":"Wound Repair Regener."},{"issue":"3","key":"10.1016\/j.actbio.2024.09.019_bib0040","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cytogfr.2014.12.001","article-title":"IGFBP-2: the dark horse in metabolism and cancer","volume":"26","author":"Russo","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0041","doi-asserted-by":"crossref","first-page":"11542","DOI":"10.1038\/srep11542","article-title":"Latent progenitor cells as potential regulators for tympanic membrane regeneration","volume":"5","author":"Kim","year":"2015","journal-title":"Sci. Rep."},{"issue":"1\u20132","key":"10.1016\/j.actbio.2024.09.019_bib0042","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0378-5173(88)90032-4","article-title":"Methods for evaluating the puncture and shear properties of pharmaceutical polymeric films","volume":"45","author":"Radebaugh","year":"1988","journal-title":"Int. J. Pharm."},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0043","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/jbm.b.31862","article-title":"Guided orientation of cardiomyocytes on electrospun aligned nanofibers for cardiac tissue engineering","volume":"98","author":"Kai","year":"2011","journal-title":"J. Biomed. Mater. Res. Part B: Appl. Biomater."},{"issue":"9","key":"10.1016\/j.actbio.2024.09.019_bib0044","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1039\/b705112c","article-title":"Anisotropic wetting on tunable micro-wrinkled surfaces","volume":"3","author":"Chung","year":"2007","journal-title":"Soft. Matter."},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0045","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s40478-023-01557-2","article-title":"IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma","volume":"11","author":"Kunhiraman","year":"2023","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.actbio.2024.09.019_bib0046","series-title":"Growth Factors, Differentiation Factors, and Cytokines","first-page":"18","article-title":"Epidermal growth factor: biology and properties of its gene and protein precursor","author":"Mroczkowski","year":"1990"},{"issue":"25","key":"10.1016\/j.actbio.2024.09.019_bib0047","doi-asserted-by":"crossref","first-page":"29293","DOI":"10.1021\/acsami.1c04022","article-title":"Macro) Molecular imprinting of proteins on PCL electrospun scaffolds","volume":"13","author":"Perez-Puyana","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"6","key":"10.1016\/j.actbio.2024.09.019_bib0048","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1021\/bm400263d","article-title":"Carbohydrate-decorated PCL fibers for specific protein adhesion","volume":"14","author":"Lancu\u0161ki","year":"2013","journal-title":"Biomacromolecules"},{"issue":"7","key":"10.1016\/j.actbio.2024.09.019_bib0049","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jbiomech.2010.12.023","article-title":"Biomechanics of the tympanic membrane","volume":"44","author":"Volandri","year":"2011","journal-title":"J. Biomech."},{"issue":"1","key":"10.1016\/j.actbio.2024.09.019_bib0050","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1017\/S0022215111002817","article-title":"Functional results of temporalis fascia versus cartilage tympanoplasty in patients with bilateral chronic otitis media","volume":"126","author":"Onal","year":"2012","journal-title":"J. Laryngol. Otol."},{"issue":"12","key":"10.1016\/j.actbio.2024.09.019_bib0051","doi-asserted-by":"crossref","first-page":"5639","DOI":"10.1007\/s00405-022-07427-2","article-title":"Transtympanic soft tissue tympanoplasty can replace conventional techniques elevating tympanic membranes","volume":"279","author":"Ha","year":"2022","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"10.1016\/j.actbio.2024.09.019_bib0052","doi-asserted-by":"crossref","unstructured":"X. Yao, B.M. Teh, H. Li, Y. Hu, J. Huang, C. Lv, S. Bu, M. Zheng, Y. Shen, Acellular collagen scaffold with basic fibroblast growth factor for repair of traumatic tympanic membrane perforation in a rat model, Otolaryngol.\u2013Head Neck Surg. 164(2) (2021) 381\u2013390.","DOI":"10.1177\/0194599820938345"},{"key":"10.1016\/j.actbio.2024.09.019_bib0053","unstructured":"L. Benington, Development and characterisation of an optimised basic fibroblast growth factor (FGF-2) formulation for the repair of chronic tympanic membrane perforations, (2020)."},{"issue":"4","key":"10.1016\/j.actbio.2024.09.019_bib0054","doi-asserted-by":"crossref","first-page":"e497","DOI":"10.1097\/MAO.0000000000003468","article-title":"Mesenchymal stem cells for treatment of delayed-healing tympanic membrane perforations using hyaluronate-based laminas as a delivery system: an animal model with histopathologic study","volume":"43","author":"Shahal","year":"2022","journal-title":"Otol. Neurotol."},{"issue":"11","key":"10.1016\/j.actbio.2024.09.019_bib0055","doi-asserted-by":"crossref","first-page":"3605","DOI":"10.1089\/ten.tea.2008.0689","article-title":"Electrical stimulation of nerve cells using conductive nanofibrous scaffolds for nerve tissue engineering","volume":"15","author":"Ghasemi-Mobarakeh","year":"2009","journal-title":"Tissue Eng. Part A"},{"issue":"28","key":"10.1016\/j.actbio.2024.09.019_bib0056","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1016\/j.biomaterials.2009.05.057","article-title":"Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering","volume":"30","author":"Prabhakaran","year":"2009","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.actbio.2024.09.019_bib0057","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.actbio.2009.07.024","article-title":"Electrospun collagen\u2013chitosan nanofiber: a biomimetic extracellular matrix for endothelial cell and smooth muscle cell","volume":"6","author":"Chen","year":"2010","journal-title":"Acta Biomater."},{"issue":"7\u20138","key":"10.1016\/j.actbio.2024.09.019_bib0058","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1089\/ten.2005.11.1149","article-title":"Grafting of gelatin on electrospun poly (caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell orientation","volume":"11","author":"Ma","year":"2005","journal-title":"Tissue Eng."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124005373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124005373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T13:00:04Z","timestamp":1729342804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706124005373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":58,"alternative-id":["S1742706124005373"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2024.09.019","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Latent stem cell-stimulating radially aligned electrospun nanofibrous patches for chronic tympanic membrane perforation therapy","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2024.09.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd on behalf of Acta Materialia Inc.","name":"copyright","label":"Copyright"}]}}