{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:14:37Z","timestamp":1790792077230,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01 HL146373"],"award-info":[{"award-number":["P01 HL146373"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL148227"],"award-info":[{"award-number":["R01 HL148227"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R00HL148646-01"],"award-info":[{"award-number":["R00HL148646-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL135254"],"award-info":[{"award-number":["R01 HL135254"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["R35GM155242"],"award-info":[{"award-number":["R35GM155242"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CMMI-2332978"],"award-info":[{"award-number":["CMMI-2332978"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005200","name":"New Jersey Commission on Spinal Cord Research","doi-asserted-by":"publisher","award":["CSCR23IRG005"],"award-info":[{"award-number":["CSCR23IRG005"]}],"id":[{"id":"10.13039\/100005200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005200","name":"New Jersey Commission on Spinal Cord Research","doi-asserted-by":"publisher","award":["R01 HL148014"],"award-info":[{"award-number":["R01 HL148014"]}],"id":[{"id":"10.13039\/100005200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005200","name":"New Jersey Commission on Spinal Cord Research","doi-asserted-by":"publisher","award":["P01 HL40387"],"award-info":[{"award-number":["P01 HL40387"]}],"id":[{"id":"10.13039\/100005200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005200","name":"New Jersey Commission on Spinal Cord Research","doi-asserted-by":"publisher","award":["R01 HL159256"],"award-info":[{"award-number":["R01 HL159256"]}],"id":[{"id":"10.13039\/100005200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004008","name":"National Institute of Health","doi-asserted-by":"publisher","award":["P01 HL146373"],"award-info":[{"award-number":["P01 HL146373"]}],"id":[{"id":"10.13039\/501100004008","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004008","name":"National Institute of Health","doi-asserted-by":"publisher","award":["R01 HL135254"],"award-info":[{"award-number":["R01 HL135254"]}],"id":[{"id":"10.13039\/501100004008","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004008","name":"National Institute of Health","doi-asserted-by":"publisher","award":["R00HL148646-01"],"award-info":[{"award-number":["R00HL148646-01"]}],"id":[{"id":"10.13039\/501100004008","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.actbio.2024.10.004","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T09:27:29Z","timestamp":1728552449000},"page":"329-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Rupture mechanics of blood clots: Influence of fibrin network structure on the rupture resistance"],"prefix":"10.1016","volume":"190","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7512-2948","authenticated-orcid":false,"given":"Ranjini K.","family":"Ramanujam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3321-9899","authenticated-orcid":false,"given":"Farkhad","family":"Maksudov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca A.","family":"Risman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0643-1496","authenticated-orcid":false,"given":"Rustem I.","family":"Litvinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W.","family":"Weisel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John L.","family":"Bassani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeri","family":"Barsegov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1939-907X","authenticated-orcid":false,"given":"Prashant K.","family":"Purohit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1213-4447","authenticated-orcid":false,"given":"Valerie","family":"Tutwiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.actbio.2024.10.004_bib0001","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1161\/ATVBAHA.108.177402","article-title":"Tissue factor in coagulation: which? where? when?","volume":"29","author":"Butenas","year":"2009","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.actbio.2024.10.004_bib0002","first-page":"405","article-title":"Fibrin formation, structure and properties","author":"Weisel","year":"2017","journal-title":"Fibrous Prot.: Struct. Mech."},{"key":"10.1016\/j.actbio.2024.10.004_bib0003","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.matbio.2016.08.003","article-title":"Fibrin mechanical properties and their structural origins","volume":"60","author":"Litvinov","year":"2017","journal-title":"Matrix Biol."},{"issue":"8","key":"10.1016\/j.actbio.2024.10.004_bib0004","doi-asserted-by":"crossref","first-page":"e347","DOI":"10.1161\/CIR.0000000000001209","article-title":"2024 heart disease and stroke statistics: a report of US and global data from the American heart association","volume":"149","author":"Martin","year":"2024","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.actbio.2024.10.004_bib0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.mpsur.2024.02.011","article-title":"Diseases of the blood vessels and thrombosis","volume":"42","author":"Stocco","year":"2024","journal-title":"Surgery (Oxford)"},{"issue":"2","key":"10.1016\/j.actbio.2024.10.004_bib0006","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/2042098615572333","article-title":"Bleeding risk with systemic thrombolytic therapy for pulmonary embolism: scope of the problem","volume":"6","author":"Daley","year":"2015","journal-title":"Ther. Adv. Drug Saf."},{"issue":"9221","key":"10.1016\/j.actbio.2024.10.004_bib0007","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/S0140-6736(00)02382-5","article-title":"Oral contraceptives and fatal pulmonary embolism","volume":"355","author":"Parkin","year":"2000","journal-title":"The Lancet"},{"issue":"10","key":"10.1016\/j.actbio.2024.10.004_bib0008","doi-asserted-by":"crossref","first-page":"S294","DOI":"10.1097\/01.CCM.0000183157.15533.4C","article-title":"Pulmonary embolism during and after pregnancy","volume":"33","author":"Stone","year":"2005","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.actbio.2024.10.004_bib0009","series-title":"Textbook of Pulmonary Vascular Disease","first-page":"1253","article-title":"Risk factors for chronic thromboembolic pulmonary hypertension","author":"Bonderman","year":"2011"},{"issue":"30","key":"10.1016\/j.actbio.2024.10.004_bib0010","doi-asserted-by":"crossref","first-page":"4928","DOI":"10.1200\/JCO.2006.06.5870","article-title":"Unsuspected pulmonary emboli in cancer patients: clinical correlates and relevance","volume":"24","author":"O'Connell","year":"2006","journal-title":"J. Clin. Oncol."},{"issue":"07","key":"10.1016\/j.actbio.2024.10.004_bib0011","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1160\/TH14-01-0032","article-title":"Fibrin clot properties and their modulation in thrombotic disorders","volume":"112","author":"Undas","year":"2014","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.actbio.2024.10.004_bib0012","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8196256","article-title":"Prothrombotic fibrin clot phenotype in patients with deep vein thrombosis and pulmonary embolism: a new risk factor for recurrence","author":"Undas","year":"2017","journal-title":"Biomed. Res. Int."},{"issue":"1","key":"10.1016\/j.actbio.2024.10.004_bib0013","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0006-3495(96)79596-6","article-title":"Fibrinogen Dusart: electron microscopy of molecules, fibers and clots, and viscoelastic properties of clots","volume":"70","author":"Collet","year":"1996","journal-title":"Biophys. J."},{"issue":"11","key":"10.1016\/j.actbio.2024.10.004_bib0014","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1161\/01.ATV.0000241589.52950.4c","article-title":"Altered fibrin architecture is associated with hypofibrinolysis and premature coronary atherothrombosis","volume":"26","author":"Collet","year":"2006","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"11","key":"10.1016\/j.actbio.2024.10.004_bib0015","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1160\/th14-02-0184","article-title":"Clot properties and cardiovascular disease","volume":"112","author":"Bridge","year":"2014","journal-title":"Thromb. Haemost."},{"issue":"27","key":"10.1016\/j.actbio.2024.10.004_bib0016","article-title":"Biomechanics, energetics and structural basis of rupture of fibrin networks","volume":"12","author":"Ramanujam","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0017","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.actbio.2022.12.028","article-title":"Fracture toughness of fibrin gels as a function of protein volume fraction: mechanical origins","volume":"159","author":"Garyfallogiannis","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0018","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.actbio.2021.03.052","article-title":"Blood clot fracture properties are dependent on red blood cell and fibrin content","volume":"127","author":"Fereidoonnezhad","year":"2021","journal-title":"Acta Biomater."},{"issue":"11","key":"10.1016\/j.actbio.2024.10.004_bib0019","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1161\/01.CIR.95.11.2508","article-title":"Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction","volume":"95","author":"Berkowitz","year":"1997","journal-title":"Circulation"},{"issue":"35","key":"10.1016\/j.actbio.2024.10.004_bib0020","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc0496","article-title":"Rupture of blood clots: mechanics and pathophysiology","volume":"6","author":"Tutwiler","year":"2020","journal-title":"Sci. Adv."},{"issue":"21","key":"10.1016\/j.actbio.2024.10.004_bib0021","doi-asserted-by":"crossref","first-page":"4184","DOI":"10.1039\/D4SM00042K","article-title":"Mechanics and microstructure of blood plasma clots in shear driven rupture","volume":"20","author":"Ramanujam","year":"2024","journal-title":"Soft Matter"},{"issue":"7","key":"10.1016\/j.actbio.2024.10.004_bib0022","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1501778","article-title":"Microscale spatial heterogeneity of protein structural transitions in fibrin matrices","volume":"2","author":"Fleissner","year":"2016","journal-title":"Sci. Adv."},{"issue":"5","key":"10.1016\/j.actbio.2024.10.004_bib0023","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1111\/jth.14002","article-title":"An international study on the feasibility of a standardized combined plasma clot turbidity and lysis assay: communication from the SSC of the ISTH","volume":"16","author":"Pieters","year":"2018","journal-title":"J. Thromb. Haemostasis"},{"issue":"6","key":"10.1016\/j.actbio.2024.10.004_bib0024","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1016\/j.actbio.2011.02.026","article-title":"Protein unfolding accounts for the unusual mechanical behavior of fibrin networks","volume":"7","author":"Purohit","year":"2011","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0025","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.actbio.2021.06.046","article-title":"Strength and deformability of fibrin clots: biomechanics, thermodynamics, and mechanisms of rupture","volume":"131","author":"Tutwiler","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0026","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.actbio.2021.09.050","article-title":"Strength, deformability and toughness of uncrosslinked fibrin fibers from theoretical reconstruction of stress-strain curves","volume":"136","author":"Maksudov","year":"2021","journal-title":"Acta Biomater."},{"issue":"5","key":"10.1016\/j.actbio.2024.10.004_bib0027","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1111\/j.1538-7836.2010.03745.x","article-title":"The mechanical properties of single fibrin fibers","volume":"8","author":"Liu","year":"2010","journal-title":"J. Thromb. Haemostasis"},{"issue":"6","key":"10.1016\/j.actbio.2024.10.004_bib0028","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.bpj.2016.02.021","article-title":"Fibrin fiber stiffness is strongly affected by fiber diameter, but not by fibrinogen glycation","volume":"110","author":"Li","year":"2016","journal-title":"Biophys. J."},{"key":"10.1016\/j.actbio.2024.10.004_bib0029","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s12013-007-9001-4","article-title":"A comparison of the mechanical and structural properties of fibrin fibers with other protein fibers","volume":"49","author":"Guthold","year":"2007","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.actbio.2024.10.004_bib0030","series-title":"Statistics of Extremes","author":"Gumbel","year":"1958"},{"key":"10.1016\/j.actbio.2024.10.004_bib0031","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ijsolstr.2019.03.033","article-title":"Parameters controlling the strength of stochastic fibrous materials","volume":"168","author":"Deogekar","year":"2019","journal-title":"Int. J. Solids Struct."},{"key":"10.1016\/j.actbio.2024.10.004_bib0032","series-title":"Probabilistic Mechanics of Quasibrittle Structures: Strength, Lifetime, and Size Effect","author":"Bazant","year":"2017"},{"issue":"2","key":"10.1016\/j.actbio.2024.10.004_bib0033","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/1056789515576863","article-title":"Stochastic micromechanical damage modeling of progressive fiber breakage for longitudinal fiber-reinforced composites","volume":"25","author":"Ju","year":"2016","journal-title":"Int. J. Damage Mech."},{"issue":"7","key":"10.1016\/j.actbio.2024.10.004_bib0034","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1177\/1056789508092418","article-title":"Micromechanical elastoplastic damage mechanics for elliptical fiber-reinforced composites with progressive partial fiber debonding","volume":"18","author":"Ju","year":"2009","journal-title":"Int. J. Damage Mech."},{"issue":"1","key":"10.1016\/j.actbio.2024.10.004_bib0035","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.1038\/s41598-017-05601-9","article-title":"Activated monocytes enhance platelet-driven contraction of blood clots via tissue factor expression","volume":"7","author":"Peshkova","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2024.10.004_bib0036","series-title":"Cellular solids: Structure and Properties","first-page":"175","author":"Ashby","year":"1997"},{"issue":"7","key":"10.1016\/j.actbio.2024.10.004_bib0037","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/nmat1666","article-title":"Solvent control of crack dynamics in a reversible hydrogel","volume":"5","author":"Baumberger","year":"2006","journal-title":"Nat. Mater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0038","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.actbio.2021.06.046","article-title":"Strength and deformability of fibrin clots: biomechanics, thermodynamics, and mechanisms of rupture","volume":"131","author":"Tutwiler","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.10.004_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2022.105328","article-title":"Biomechanical origins of inherent tension in fibrin networks","volume":"133","author":"Spiewak","year":"2022","journal-title":"J. Mech. Behav. Biomed. Mater."},{"issue":"24","key":"10.1016\/j.actbio.2024.10.004_bib0040","doi-asserted-by":"crossref","first-page":"8991","DOI":"10.1073\/pnas.84.24.8991","article-title":"Twisting of fibrin fibers limits their radial growth","volume":"84","author":"Weisel","year":"1987","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.actbio.2024.10.004_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2019.05.006","article-title":"The central role of thrombin in bleeding disorders","volume":"38","author":"Negrier","year":"2019","journal-title":"Blood Rev."},{"issue":"4","key":"10.1016\/j.actbio.2024.10.004_bib0042","first-page":"487","article-title":"Thrombin and fibrinogen \u03b3\u2032 impact clot structure by marked effects on intrafibrillar structure and protofibril packing","volume":"127","author":"Domingues","year":"2016","journal-title":"Blood, J. Am. Soc. Hematol."},{"issue":"3","key":"10.1016\/j.actbio.2024.10.004_bib0043","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.blre.2006.11.001","article-title":"Thrombin generation and fibrin clot structure","volume":"21","author":"Wolberg","year":"2007","journal-title":"Blood Rev."},{"issue":"6","key":"10.1016\/j.actbio.2024.10.004_bib0044","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1161\/ATVBAHA.112.249789","article-title":"Thrombus growth and embolism on tissue factor-bearing collagen surfaces under flow: role of thrombin with and without fibrin","volume":"32","author":"Colace","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.actbio.2024.10.004_bib0045","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.transci.2007.12.005","article-title":"Thrombin generation, fibrin clot formation and hemostasis","volume":"38","author":"Wolberg","year":"2008","journal-title":"Transfus. Apheresis Sci."},{"issue":"1","key":"10.1016\/j.actbio.2024.10.004_bib0046","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0006-3495(92)81594-1","article-title":"Computer modeling of fibrin polymerization kinetics correlated with electron microscope and turbidity observations: clot structure and assembly are kinetically controlled","volume":"63","author":"Weisel","year":"1992","journal-title":"Biophys. J."},{"issue":"8","key":"10.1016\/j.actbio.2024.10.004_bib0047","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.bpj.2009.12.4312","article-title":"Stiffening of individual fibrin fibers equitably distributes strain and strengthens networks","volume":"98","author":"Hudson","year":"2010","journal-title":"Biophys. J."},{"issue":"5","key":"10.1016\/j.actbio.2024.10.004_bib0048","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s10237-021-01467-z","article-title":"Hyper-viscoelastic damage modeling of whole blood clot under large deformation","volume":"20","author":"Rausch","year":"2021","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.actbio.2024.10.004_bib0049","article-title":"Nonuniform internal structure of fibrin fibers: protein density and bond density strongly decrease with increasing diameter","volume":"2017","author":"Li","year":"2017","journal-title":"Biomed. Res. Int."},{"issue":"13","key":"10.1016\/j.actbio.2024.10.004_bib0050","doi-asserted-by":"crossref","first-page":"4015","DOI":"10.1182\/bloodadvances.2022006977","article-title":"Fibrin protofibril packing and clot stability are enhanced by extended knob-hole interactions and catch-slip bonds","volume":"6","author":"Asquith","year":"2022","journal-title":"Blood Adv."},{"key":"10.1016\/j.actbio.2024.10.004_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.eml.2021.101444","article-title":"Fracture mechanics of blood clots: measurements of toughness and critical length scales","volume":"48","author":"Liu","year":"2021","journal-title":"Extreme Mech. Lett."},{"issue":"5","key":"10.1016\/j.actbio.2024.10.004_bib0052","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1016\/S0006-3495(99)77113-4","article-title":"Structural origins of fibrin clot rheology","volume":"77","author":"Ryan","year":"1999","journal-title":"Biophys. J."},{"key":"10.1016\/j.actbio.2024.10.004_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.eml.2022.101757","article-title":"Rheology of fibrous gels under compression","volume":"54","author":"Sun","year":"2022","journal-title":"Extreme Mech. Lett."},{"issue":"4","key":"10.1016\/j.actbio.2024.10.004_bib0054","first-page":"644","article-title":"Rheological properties of fibrin clots. Effects of fibrinogen concentration, Factor XIII deficiency, and Factor XIII inhibition","volume":"86","author":"Glover","year":"1975","journal-title":"J. Lab. Clin. Med."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124005853?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124005853?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:26:00Z","timestamp":1778624760000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706124005853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":54,"alternative-id":["S1742706124005853"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2024.10.004","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rupture mechanics of blood clots: Influence of fibrin network structure on the rupture resistance","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2024.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd on behalf of Acta Materialia Inc.","name":"copyright","label":"Copyright"}]}}