{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:48:30Z","timestamp":1791319710220,"version":"4.3.1"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271058"],"award-info":[{"award-number":["82271058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015508","name":"Shandong Academy of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015508","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014103","name":"Key Technology Research and Development Program of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.actbio.2024.12.005","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T02:47:51Z","timestamp":1733280471000},"page":"189-205","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["3D printing of stiff, tough, and ROS-scavenging nanocomposite hydrogel scaffold for in situ corneal repair"],"prefix":"10.1016","volume":"192","author":[{"given":"Tan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingjun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuli","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyun","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2024.12.005_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2021.121320","article-title":"Exosomes-loaded thermosensitive hydrogels for corneal epithelium and stroma regeneration","volume":"280","author":"Tang","year":"2022","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.actbio.2024.12.005_bib0002","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","article-title":"Global survey of corneal transplantation and eye banking","volume":"134","author":"Gain","year":"2016","journal-title":"JAMA Ophthalmol."},{"issue":"30","key":"10.1016\/j.actbio.2024.12.005_bib0003","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202006335","article-title":"Hydrogels as emerging materials for cornea wound healing","volume":"17","author":"Khosravimelal","year":"2021","journal-title":"Small"},{"issue":"21","key":"10.1016\/j.actbio.2024.12.005_bib0004","article-title":"ECM-like adhesive hydrogel for the regeneration of large corneal stromal defects","volume":"12","author":"Wang","year":"2023","journal-title":"Adv. Healthc. Mater."},{"issue":"21","key":"10.1016\/j.actbio.2024.12.005_bib0005","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202201576","article-title":"Natural dual-crosslinking bioadhesive hydrogel for corneal regeneration in large-size defects","volume":"11","author":"Zhao","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0006","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.actbio.2017.05.060","article-title":"Preparation of acellular scaffold for corneal tissue engineering by supercritical carbon dioxide extraction technology","volume":"58","author":"Huang","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0007","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.exer.2018.05.010","article-title":"3D bioprinting of a corneal stroma equivalent","volume":"173","author":"Isaacson","year":"2018","journal-title":"Exp. Eye Res."},{"issue":"10","key":"10.1016\/j.actbio.2024.12.005_bib0008","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1002\/jbm.a.35453","article-title":"Biocompatibility of poly(ethylene glycol) and poly(acrylic acid) interpenetrating network hydrogel by intrastromal implantation in rabbit cornea","volume":"103","author":"Zheng","year":"2015","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"24","key":"10.1016\/j.actbio.2024.12.005_bib0009","doi-asserted-by":"crossref","first-page":"3311","DOI":"10.1016\/S0142-9612(01)00168-5","article-title":"An overview of the development of artificial corneas with porous skirts and the use of PHEMA for such an application","volume":"22","author":"Chirila","year":"2001","journal-title":"Biomaterials"},{"issue":"38","key":"10.1016\/j.actbio.2024.12.005_bib0010","article-title":"Anisotropic hybrid hydrogels with superior mechanical properties reminiscent of tendons or ligaments","volume":"29","author":"Choi","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"4","key":"10.1016\/j.actbio.2024.12.005_bib0011","doi-asserted-by":"crossref","first-page":"e372","DOI":"10.1038\/am.2017.33","article-title":"Tough, self-healable and tissue-adhesive hydrogel with tunable multifunctionality","volume":"9","author":"Han","year":"2017","journal-title":"NPG Asia Mater."},{"issue":"9","key":"10.1016\/j.actbio.2024.12.005_bib0012","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1039\/D1TB02199K","article-title":"Fe(3+)-Coordination mediated synergistic dual-network conductive hydrogel as a sensitive and highly-stretchable strain sensor with adjustable mechanical properties","volume":"10","author":"Sun","year":"2022","journal-title":"J. Mater. Chem. B"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0013","doi-asserted-by":"crossref","first-page":"4032","DOI":"10.1038\/s41467-020-17877-z","article-title":"Stretchable hydrogels with low hysteresis and anti-fatigue fracture based on polyprotein cross-linkers","volume":"11","author":"Lei","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.actbio.2024.12.005_bib0014","first-page":"214","article-title":"Molecular design of an ultra-strong tissue adhesive hydrogel with tunable multifunctionality","volume":"29","author":"Zheng","year":"2023","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0015","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1146\/annurev-chembioeng-101220-080338","article-title":"Tough double network hydrogel and its biomedical applications","volume":"12","author":"Nonoyama","year":"2021","journal-title":"Annu. Rev. Chem. Biomol. Eng."},{"issue":"27","key":"10.1016\/j.actbio.2024.12.005_bib0016","doi-asserted-by":"crossref","first-page":"32945","DOI":"10.1021\/acsami.3c05785","article-title":"Injectable, tough, and thermoplastic supramolecular hydrogel coatings with controllable adhesion for touch sensing","volume":"15","author":"Wang","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"42","key":"10.1016\/j.actbio.2024.12.005_bib0017","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202310832","article-title":"Strong and ultra-tough ionic hydrogel based on hyperbranched macro-cross-linker: influence of topological structure on properties","volume":"62","author":"Jiang","year":"2023","journal-title":"Angew. Chem. Int. Ed."},{"issue":"14","key":"10.1016\/j.actbio.2024.12.005_bib0018","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.1039\/D0SM00271B","article-title":"Host-guest interaction-mediated fabrication of a hybrid microsphere-structured supramolecular hydrogel showing high mechanical strength","volume":"16","author":"Zhang","year":"2020","journal-title":"Soft Matter"},{"issue":"40","key":"10.1016\/j.actbio.2024.12.005_bib0019","doi-asserted-by":"crossref","first-page":"15470","DOI":"10.1039\/C7NR04722C","article-title":"A self-healable and tough nanocomposite hydrogel crosslinked by novel ultrasmall aluminum hydroxide nanoparticles","volume":"9","author":"Jiang","year":"2017","journal-title":"Nanoscale"},{"issue":"9","key":"10.1016\/j.actbio.2024.12.005_bib0020","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1039\/C6TB00135A","article-title":"Multi-responsive nanocomposite hydrogels with high strength and toughness","volume":"4","author":"Yang","year":"2016","journal-title":"J. Mater. Chem. B"},{"issue":"27","key":"10.1016\/j.actbio.2024.12.005_bib0021","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201901406","article-title":"Highly conductive, stretchable, and cell-adhesive hydrogel by nanoclay doping","volume":"15","author":"Tondera","year":"2019","journal-title":"Small"},{"issue":"3","key":"10.1016\/j.actbio.2024.12.005_bib0022","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1021\/acsnano.6b05318","article-title":"Mussel-Inspired adhesive and tough hydrogel based on nanoclay confined dopamine polymerization","volume":"11","author":"Han","year":"2017","journal-title":"ACS Nano"},{"issue":"9","key":"10.1016\/j.actbio.2024.12.005_bib0023","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202209497","article-title":"Highly stretchable and biocompatible wrinkled nanoclay-composite hydrogel with enhanced sensing capability for precise detection of myocardial infarction","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv. Mater."},{"issue":"23","key":"10.1016\/j.actbio.2024.12.005_bib0024","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201900332","article-title":"2D nanoclay for biomedical applications: regenerative medicine, therapeutic delivery, and additive manufacturing","volume":"31","author":"Gaharwar","year":"2019","journal-title":"Adv. Mater."},{"issue":"30","key":"10.1016\/j.actbio.2024.12.005_bib0025","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1002\/adma.201301034","article-title":"Clay: new opportunities for tissue regeneration and biomaterial design","volume":"25","author":"Dawson","year":"2013","journal-title":"Adv. Mater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carbpol.2016.09.057","article-title":"Laponite as a rheology modifier of alginate solutions: physical gelation and aging evolution","volume":"157","author":"D\u00e1vila","year":"2017","journal-title":"Carbohydr. Polym."},{"issue":"11","key":"10.1016\/j.actbio.2024.12.005_bib0027","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202100036","article-title":"3D printing unique nanoclay-incorporated double-network hydrogels for construction of complex tissue engineering scaffolds","volume":"10","author":"Guo","year":"2021","journal-title":"Adv. Healthc. Mater."},{"issue":"3","key":"10.1016\/j.actbio.2024.12.005_bib0028","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/ab0cf6","article-title":"3D printing of complex GelMA-based scaffolds with nanoclay","volume":"11","author":"Gao","year":"2019","journal-title":"Biofabrication"},{"issue":"16","key":"10.1016\/j.actbio.2024.12.005_bib0029","doi-asserted-by":"crossref","first-page":"7948","DOI":"10.7150\/thno.61621","article-title":"3D bioprinting in cardiac tissue engineering","volume":"11","author":"Wang","year":"2021","journal-title":"Theranostics"},{"issue":"24","key":"10.1016\/j.actbio.2024.12.005_bib0030","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201805530","article-title":"3D bioprinting in skeletal muscle tissue engineering","volume":"15","author":"Ostrovidov","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.actbio.2024.12.005_bib0031","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.actbio.2022.08.004","article-title":"Biomaterial-based 3D bioprinting strategy for orthopedic tissue engineering","volume":"156","author":"Chae","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119536","article-title":"Progress in 3D bioprinting technology for tissue\/organ regenerative engineering","volume":"226","author":"Matai","year":"2020","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.actbio.2024.12.005_bib0033","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202103691","article-title":"3D Bioprinting of cell-laden hydrogels for improved biological functionality","volume":"34","author":"Hull","year":"2022","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0034","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1039\/C9BM01236B","article-title":"Cell loaded 3D bioprinted GelMA hydrogels for corneal stroma engineering","volume":"8","author":"Bektas","year":"2019","journal-title":"Biomater. Sci."},{"issue":"7","key":"10.1016\/j.actbio.2024.12.005_bib0035","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1002\/jbm.b.34628","article-title":"High-throughput 3D bioprinting of corneal stromal equivalents","volume":"108","author":"Kutlehria","year":"2020","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0036","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.biomaterials.2018.04.034","article-title":"Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks","volume":"171","author":"Sorkio","year":"2018","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.actbio.2024.12.005_bib0037","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/ad35ea","article-title":"Development of a novel bioartificial cornea using 3D bioprinting based on electrospun micro-nanofibrous decellularized extracellular matrix","volume":"16","author":"Zhang","year":"2024","journal-title":"Biofabrication"},{"issue":"3","key":"10.1016\/j.actbio.2024.12.005_bib0038","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/ad35eb","article-title":"3D bioprinting of stromal cells-laden artificial cornea based on visible light-crosslinkable bioinks forming multilength networks","volume":"16","author":"Lee","year":"2024","journal-title":"Biofabrication"},{"key":"10.1016\/j.actbio.2024.12.005_bib0039","first-page":"234","article-title":"3D printed biomimetic epithelium\/stroma bilayer hydrogel implant for corneal regeneration","volume":"17","author":"He","year":"2022","journal-title":"Bioact. Mater."},{"issue":"11","key":"10.1016\/j.actbio.2024.12.005_bib0040","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202205878","article-title":"Biomimetic convex implant for corneal regeneration through 3D printing","volume":"10","author":"Xu","year":"2023","journal-title":"Adv. Sci."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0041","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1186\/s12951-024-02499-0","article-title":"Dual-ROS-scavenging and dual-lingering nanozyme-based eye drops alleviate dry eye disease","volume":"22","author":"Zhang","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"2","key":"10.1016\/j.actbio.2024.12.005_bib0042","doi-asserted-by":"crossref","first-page":"809","DOI":"10.7150\/ijbs.63219","article-title":"The advanced glycation end-products (AGEs)\/ROS\/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration","volume":"18","author":"Wan","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"9","key":"10.1016\/j.actbio.2024.12.005_bib0043","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.3390\/biom13091385","article-title":"ROS-Mediated fragmentation alters the effects of hyaluronan on corneal epithelial wound healing","volume":"13","author":"Lin","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.actbio.2024.12.005_bib0044","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.actbio.2023.01.016","article-title":"An electrospun scaffold functionalized with a ROS-scavenging hydrogel stimulates ocular wound healing","volume":"158","author":"Shi","year":"2023","journal-title":"Acta Biomater."},{"issue":"9","key":"10.1016\/j.actbio.2024.12.005_bib0045","doi-asserted-by":"crossref","first-page":"5503","DOI":"10.1167\/iovs.14-16247","article-title":"Protective effects of L-carnitine against oxidative injury by hyperosmolarity in human corneal epithelial cells","volume":"56","author":"Hua","year":"2015","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.actbio.2024.12.005_bib0046","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110452","article-title":"Oxidative stress and inflammation in osteoarthritis pathogenesis: role of polyphenols","volume":"129","author":"Ansari","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"19","key":"10.1016\/j.actbio.2024.12.005_bib0047","doi-asserted-by":"crossref","first-page":"18732","DOI":"10.1021\/acsnano.3c01940","article-title":"Microenvironment-Responsive metal-phenolic nanozyme release platform with antibacterial, ROS scavenging, and osteogenesis for periodontitis","volume":"17","author":"Xu","year":"2023","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0048","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1038\/s41467-020-16544-7","article-title":"Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases","volume":"11","author":"Liu","year":"2020","journal-title":"Nat. Commun."},{"issue":"17","key":"10.1016\/j.actbio.2024.12.005_bib0049","doi-asserted-by":"crossref","first-page":"16573","DOI":"10.1021\/acsnano.3c02407","article-title":"Polydopamine-Mediated immunomodulatory patch for diabetic periodontal tissue regeneration assisted by metformin-ZIF system","volume":"17","author":"Gong","year":"2023","journal-title":"ACS Nano"},{"issue":"29","key":"10.1016\/j.actbio.2024.12.005_bib0050","doi-asserted-by":"crossref","first-page":"32901","DOI":"10.1021\/acsami.2c06981","article-title":"Polydopamine-Based nanocomposite as a biomimetic antioxidant with a variety of enzymatic activities for Parkinson\u2019s disease","volume":"14","author":"Wang","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0051","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12951-021-00973-7","article-title":"More natural more better: triple natural anti-oxidant puerarin\/ferulic acid\/polydopamine incorporated hydrogel for wound healing","volume":"19","author":"Ou","year":"2021","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.actbio.2024.12.005_bib0052","article-title":"Development and in vitro evaluation of photocurable GelMA\/PEGDA hybrid hydrogel for corneal stromal cells delivery","volume":"27","author":"Mahdavi","year":"2021","journal-title":"Mater. Today Commun."},{"key":"10.1016\/j.actbio.2024.12.005_bib0053","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ijbiomac.2022.08.171","article-title":"Recent advances on gelatin methacrylate hydrogels with controlled microstructures for tissue engineering","volume":"221","author":"Zhang","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"issue":"49","key":"10.1016\/j.actbio.2024.12.005_bib0054","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202300707","article-title":"Dopamine-Based high-transparent hydrogel as bioadhesive for sutureless ocular tissue repair","volume":"33","author":"Qian","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.actbio.2024.12.005_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2023.213539","article-title":"Visible light-induced 3D bioprinted injectable scaffold for minimally invasive tissue regeneration","volume":"153","author":"Tilton","year":"2023","journal-title":"Biomater. Adv."},{"issue":"2","key":"10.1016\/j.actbio.2024.12.005_bib0056","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/jcb.21309","article-title":"Constitutive collagenase-1 synthesis through MAPK pathways is mediated, in part, by endogenous IL-1alpha during fibrotic repair in corneal stroma","volume":"102","author":"Jung","year":"2007","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.actbio.2024.12.005_bib0057","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.mechmat.2015.09.010","article-title":"Indentation analysis of biphasic viscoelastic hydrogels","volume":"92","author":"Toohey","year":"2016","journal-title":"Mech. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0058","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s11095-020-02983-w","article-title":"Fouling behavior during sterile filtration of different glycoconjugate serotypes used in conjugate vaccines","volume":"38","author":"Emami","year":"2021","journal-title":"Pharm. Res."},{"key":"10.1016\/j.actbio.2024.12.005_bib0059","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121597","article-title":"Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties","volume":"286","author":"Tu","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2024.12.005_bib0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108670","article-title":"Effective elastic modulus of an intact cornea related to indentation behavior: a comparison between the Hertz model and Johnson-Kendall-Roberts model","volume":"209","author":"Ren","year":"2021","journal-title":"Exp. Eye Res."},{"issue":"5","key":"10.1016\/j.actbio.2024.12.005_bib0061","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3390\/jfb14050256","article-title":"Xeno-Free biomimetic ECM model for investigation of matrix composition and stiffness on astrocyte cell response","volume":"14","author":"Saleh","year":"2023","journal-title":"J. Func. Biomater."},{"issue":"3","key":"10.1016\/j.actbio.2024.12.005_bib0062","doi-asserted-by":"crossref","first-page":"e12338","DOI":"10.1111\/cpr.12338","article-title":"Effect of matrix stiffness on osteoblast functionalization","volume":"50","author":"Zhang","year":"2017","journal-title":"Cell Prolif."},{"issue":"5","key":"10.1016\/j.actbio.2024.12.005_bib0063","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/jbm.a.36337","article-title":"Instrumented indentation for determination of mechanical properties of human cornea after ultraviolet-A crosslinking","volume":"106","author":"Nohava","year":"2018","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"Pt 8","key":"10.1016\/j.actbio.2024.12.005_bib0064","article-title":"Structure, rheological properties, and biocompatibility of Laponite\u00ae cross-linked starch\/polyvinyl alcohol hydrogels","volume":"253","author":"Yu","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2024.12.005_bib0065","doi-asserted-by":"crossref","unstructured":"I. Erezuma, T. Eufrasio-da-Silva, N. Golafshan, K. Deo, Y.K. Mishra, M. Castilho, A.K. Gaharwar, S. Leeuwenburgh, A. Dolatshahi-Pirouz, G. Orive. Nanoclay Reinforced Biomaterials for Mending Musculoskeletal Tissue Disorders, Adv. Healthc. Mater. 10 (16) (2021) e2100217.","DOI":"10.1002\/adhm.202100217"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0066","doi-asserted-by":"crossref","DOI":"10.1063\/5.0166206","article-title":"Addition of Laponite to gelatin methacryloyl bioinks improves the rheological properties and printability to create mechanically tailorable cell culture matrices","volume":"8","author":"Davern","year":"2024","journal-title":"APL Bioeng."},{"issue":"7279","key":"10.1016\/j.actbio.2024.12.005_bib0067","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nature08693","article-title":"High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder","volume":"463","author":"Wang","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.actbio.2024.12.005_bib0068","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.126177","article-title":"Nanocomposite hydrogel based on chitosan\/laponite for sealing and repairing tracheoesophageal fistula","volume":"250","author":"Ni","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2024.12.005_bib0069","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ijbiomac.2021.07.199","article-title":"Facile extrusion 3D printing of gelatine methacrylate\/Laponite nanocomposite hydrogel with high concentration nanoclay for bone tissue regeneration","volume":"188","author":"Dong","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2024.12.005_bib0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2023.213414","article-title":"High resolution and fidelity 3D printing of Laponite and alginate ink hydrogels for tunable biomedical applications","volume":"149","author":"Munoz-Perez","year":"2023","journal-title":"Biomater. Adv."},{"issue":"13","key":"10.1016\/j.actbio.2024.12.005_bib0071","article-title":"Bioprinting a synthetic smectic clay for orthopedic applications","volume":"8","author":"Afewerki","year":"2019","journal-title":"Adv. Healthc. Mater."},{"issue":"34","key":"10.1016\/j.actbio.2024.12.005_bib0072","doi-asserted-by":"crossref","first-page":"40290","DOI":"10.1021\/acsami.1c10048","article-title":"Stretchable and bioadhesive gelatin methacryloyl-based hydrogels enabled by in situ dopamine polymerization","volume":"13","author":"Montazerian","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"39","key":"10.1016\/j.actbio.2024.12.005_bib0073","doi-asserted-by":"crossref","first-page":"33523","DOI":"10.1021\/acsami.8b10064","article-title":"Ultratough, self-healing, and tissue-adhesive hydrogel for wound dressing","volume":"10","author":"Chen","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2024.12.005_bib0074","first-page":"333","article-title":"A \"T.E.S.T.\" hydrogel bioadhesive assisted by corneal cross-linking for in situ sutureless corneal repair","volume":"25","author":"Li","year":"2023","journal-title":"Bioact. Mater."},{"issue":"10","key":"10.1016\/j.actbio.2024.12.005_bib0075","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1002\/jbm.a.36124","article-title":"Recent advancements in electrospinning design for tissue engineering applications: a review","volume":"105","author":"Kishan","year":"2017","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"12","key":"10.1016\/j.actbio.2024.12.005_bib0076","doi-asserted-by":"crossref","first-page":"5716","DOI":"10.1021\/acsabm.2c00751","article-title":"Electrospun-Reinforced suturable biodegradable artificial cornea","volume":"5","author":"Sharifi","year":"2022","journal-title":"ACS Appl. Bio Mater."},{"issue":"2\u20133","key":"10.1016\/j.actbio.2024.12.005_bib0077","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/phpp.12089","article-title":"Towards standardization of UV eye protection: what can be learned from photodermatology?","volume":"30","author":"Krutmann","year":"2014","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"issue":"12","key":"10.1016\/j.actbio.2024.12.005_bib0078","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202210224","article-title":"Compliant and Robust tissue-like hydrogels via ferric ion-induced of hierarchical structure","volume":"33","author":"Wang","year":"2023","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0079","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1038\/s41467-022-29038-5","article-title":"Measuring mechanical anisotropy of the cornea with Brillouin microscopy","volume":"13","author":"Eltony","year":"2022","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.005_bib0080","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12938-021-00948-7","article-title":"Time-varying regularity of changes in biomechanical properties of the corneas after removal of anterior corneal tissue","volume":"20","author":"Zhang","year":"2021","journal-title":"Biomed. Eng. Online"}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124007128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124007128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T23:00:12Z","timestamp":1762556412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706124007128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":80,"alternative-id":["S1742706124007128"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2024.12.005","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"3D printing of stiff, tough, and ROS-scavenging nanocomposite hydrogel scaffold for in situ corneal repair","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2024.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Acta Materialia Inc. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}