{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T04:17:18Z","timestamp":1792124238892,"version":"4.4.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing Municipality","doi-asserted-by":"publisher","award":["2024NSCQ-MSX3823"],"award-info":[{"award-number":["2024NSCQ-MSX3823"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010265","name":"Guizhou Medical University","doi-asserted-by":"publisher","award":["YJ2020-YB02"],"award-info":[{"award-number":["YJ2020-YB02"]}],"id":[{"id":"10.13039\/501100010265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260827"],"award-info":[{"award-number":["82260827"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52263014"],"award-info":[{"award-number":["52263014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.actbio.2024.12.026","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T19:23:55Z","timestamp":1734031435000},"page":"394-408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Lysozyme-targeted liposomes for enhanced tubular targeting in the treatment of acute kidney injury"],"prefix":"10.1016","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8373-3530","authenticated-orcid":false,"given":"Qianqian","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kedui","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangmin","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunyuan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangchun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0001","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/ki.2013.153","article-title":"Raising awareness of acute kidney injury: a global perspective of a silent killer","volume":"84","author":"Lewington","year":"2013","journal-title":"Kidney Int."},{"issue":"7","key":"10.1016\/j.actbio.2024.12.026_bib0002","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/ki.2009.259","article-title":"Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury","volume":"76","author":"Gandolfo","year":"2009","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0003","doi-asserted-by":"crossref","first-page":"F145","DOI":"10.1152\/ajprenal.00164.2016","article-title":"The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction","volume":"311","author":"Chevalier","year":"2016","journal-title":"Am. J. Physiol. Renal Physiol."},{"issue":"5","key":"10.1016\/j.actbio.2024.12.026_bib0004","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41581-020-00369-0","article-title":"Mitochondrial quality control in kidney injury and repair","volume":"17","author":"Tang","year":"2021","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.actbio.2024.12.026_bib0005","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.bbi.2023.02.020","article-title":"Chronic ethanol induces a pro-inflammatory switch in interleukin-1\u03b2 regulation of GABAergic signaling in the medial prefrontal cortex of male mice","volume":"110","author":"Varodayan","year":"2023","journal-title":"Brain Behav. Immun."},{"issue":"11","key":"10.1016\/j.actbio.2024.12.026_bib0006","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1016\/j.matt.2021.08.015","article-title":"Biomimetic immunomodulation by crosstalk with nanoparticulate regulatory T cells","volume":"4","author":"Li","year":"2021","journal-title":"Matter"},{"issue":"12","key":"10.1016\/j.actbio.2024.12.026_bib0007","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/nrneph.2016.156","article-title":"Nanomedicines for renal disease: current status and future applications","volume":"12","author":"Kamaly","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"issue":"7","key":"10.1016\/j.actbio.2024.12.026_bib0008","doi-asserted-by":"crossref","first-page":"6165","DOI":"10.1021\/acsnano.2c12140","article-title":"Spotlight on genetic kidney diseases: a call for drug delivery and nanomedicine solutions","volume":"17","author":"Trac","year":"2023","journal-title":"ACS Nano"},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0009","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.kint.2016.03.041","article-title":"Nanomedicines for kidney diseases","volume":"90","author":"Williams","year":"2016","journal-title":"Kidney Int."},{"issue":"13","key":"10.1016\/j.actbio.2024.12.026_bib0010","doi-asserted-by":"crossref","first-page":"4112","DOI":"10.1002\/anie.201807847","article-title":"Renal clearable luminescent gold nanoparticles: from the bench to the clinic","volume":"58","author":"Yu","year":"2019","journal-title":"Angew. Chem. Int. Ed."},{"issue":"12","key":"10.1016\/j.actbio.2024.12.026_bib0011","doi-asserted-by":"crossref","first-page":"5312","DOI":"10.1039\/C9BM01290G","article-title":"Kidney-targeted triptolide-encapsulated mesoscale nanoparticles for high-efficiency treatment of kidney injury","volume":"7","author":"Deng","year":"2019","journal-title":"Biomater. Sci."},{"issue":"6","key":"10.1016\/j.actbio.2024.12.026_bib0012","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/s41581-024-00819-z","article-title":"Physiological principles underlying the kidney targeting of renal nanomedicines","volume":"20","author":"Huang","year":"2024","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.actbio.2024.12.026_bib0013","article-title":"Theranostic lipid nanoparticles for renal cell carcinoma","volume":"13","author":"Mao","year":"2023","journal-title":"Adv. Mater."},{"issue":"31","key":"10.1016\/j.actbio.2024.12.026_bib0014","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202302314","article-title":"Regulating size and charge of liposomes in microneedles to enhance intracellular drug delivery efficiency in skin for psoriasis therapy","volume":"12","author":"Qu","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2024.12.026_bib0015","article-title":"Advances in nanotechnology versus stem cell therapy for the theranostics of Huntington's disease","volume":"87","author":"Mustafa","year":"2023","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"13","key":"10.1016\/j.actbio.2024.12.026_bib0016","doi-asserted-by":"crossref","first-page":"14816","DOI":"10.1021\/acsami.0c22381","article-title":"State-of-the-art of nanodiagnostics and nanotherapeutics against SARS-CoV-2","volume":"13","author":"Derakhshan","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"696","key":"10.1016\/j.actbio.2024.12.026_bib0017","doi-asserted-by":"crossref","first-page":"eabm1262","DOI":"10.1126\/scitranslmed.abm1262","article-title":"Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia","volume":"15","author":"Moles","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.actbio.2024.12.026_bib0018","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.actbio.2019.05.054","article-title":"Macrophage-derived exosome-mimetic hybrid vesicles for tumor targeted drug delivery","volume":"94","author":"Rayamajhi","year":"2019","journal-title":"Acta Biomater."},{"issue":"6","key":"10.1016\/j.actbio.2024.12.026_bib0019","first-page":"258","article-title":"Renal handling of endogenous lysozyme in the rat","volume":"6","author":"Cojocel","year":"1983","journal-title":"Ren. Physiol."},{"issue":"6","key":"10.1016\/j.actbio.2024.12.026_bib0020","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.3390\/ijms21061922","article-title":"Design, synthesis, and renal targeting of methylprednisolone-lysozyme","volume":"21","author":"Pan","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.actbio.2024.12.026_bib0021","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/j.biomaterials.2008.11.035","article-title":"The targeting of 14-succinate triptolide-lysozyme conjugate to proximal renal tubular epithelial cells","volume":"30","author":"Zhang","year":"2009","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0022","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jconrel.2011.08.041","article-title":"Imatinib-ULS-lysozyme: a proximal tubular cell-targeted conjugate of imatinib for the treatment of renal diseases","volume":"157","author":"Dolman","year":"2012","journal-title":"J. Control. Rel.: Off. J. Control. Rel. Soc."},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0023","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nrm778","article-title":"Megalin and cubilin: multifunctional endocytic receptors","volume":"3","author":"Christensen","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0024","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/S0002-9440(10)65238-8","article-title":"Megalin knockout mice as an animal model of low molecular weight proteinuria","volume":"155","author":"Leheste","year":"1999","journal-title":"Am. J. Pathol."},{"issue":"5","key":"10.1016\/j.actbio.2024.12.026_bib0025","doi-asserted-by":"crossref","first-page":"12","DOI":"10.53388\/TMR20190831133","article-title":"Natural products as a crucial source of anti-inflammatory drugs: recent trends and advancements","volume":"4","author":"Wang","year":"2019","journal-title":"Tradit. Med. Res."},{"issue":"10","key":"10.1016\/j.actbio.2024.12.026_bib0026","doi-asserted-by":"crossref","first-page":"7728","DOI":"10.1021\/acs.nanolett.0c03279","article-title":"Inflammation-targeted celastrol nanodrug attenuates collagen-induced arthritis through NF-\u03baB and Notch1 pathways","volume":"20","author":"An","year":"2020","journal-title":"Nano Lett."},{"issue":"11","key":"10.1016\/j.actbio.2024.12.026_bib0027","doi-asserted-by":"crossref","first-page":"16982","DOI":"10.1021\/acsnano.1c04996","article-title":"Lipid nanoparticles\u2013from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement","volume":"15","author":"Tenchov","year":"2021","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0028","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s13020-021-00525-z","article-title":"Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity","volume":"16","author":"Cheng","year":"2021","journal-title":"Chin. Med."},{"key":"10.1016\/j.actbio.2024.12.026_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2021.116466","article-title":"Antitumor and toxicity study of mitochondria-targeted triptolide derivatives using triphenylphosphine (TPP(+)) as a carrier","volume":"50","author":"Song","year":"2021","journal-title":"Bioorg. Med. Chem."},{"issue":"1\u20132","key":"10.1016\/j.actbio.2024.12.026_bib0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0378-5173(02)00129-1","article-title":"Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating","volume":"240","author":"Levchenko","year":"2002","journal-title":"Int. J. Pharmacy"},{"issue":"13","key":"10.1016\/j.actbio.2024.12.026_bib0031","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1016\/j.biomaterials.2010.01.065","article-title":"Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles","volume":"31","author":"He","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2024.12.026_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-bioeng-071811-150124","article-title":"The effect of nanoparticle size, shape, and surface chemistry on biological systems","volume":"14","author":"Albanese","year":"2012","journal-title":"Annu. Rev. Biomed. Eng."},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0033","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1111\/j.1523-1755.2004.00920.x","article-title":"Cationic charge-preferential IgG reabsorption in the renal proximal tubules","volume":"66","author":"Takahashi","year":"2004","journal-title":"Kidney Int."},{"issue":"13","key":"10.1016\/j.actbio.2024.12.026_bib0034","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1016\/j.biomaterials.2011.01.021","article-title":"The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles","volume":"32","author":"Xiao","year":"2011","journal-title":"Biomaterials"},{"issue":"26","key":"10.1016\/j.actbio.2024.12.026_bib0035","doi-asserted-by":"crossref","first-page":"eabb8133","DOI":"10.1126\/sciadv.abb8133","article-title":"Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines","volume":"6","author":"Dirisala","year":"2020","journal-title":"Sci. Adv."},{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0036","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/gt.2017.5","article-title":"Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems","volume":"24","author":"Guan","year":"2017","journal-title":"Gene Ther."},{"issue":"1\u20132","key":"10.1016\/j.actbio.2024.12.026_bib0037","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0005-2736(00)00343-6","article-title":"Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures","volume":"1510","author":"Semple","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0038","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s00281-021-00842-3","article-title":"Thymus and autoimmunity","volume":"43","author":"Marx","year":"2021","journal-title":"Semin. Immunopathol."},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0039","doi-asserted-by":"crossref","first-page":"3556","DOI":"10.1007\/s12274-021-3894-x","article-title":"Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment","volume":"15","author":"Wu","year":"2022","journal-title":"Nano Res."},{"issue":"13","key":"10.1016\/j.actbio.2024.12.026_bib0040","doi-asserted-by":"crossref","first-page":"5330","DOI":"10.1021\/acs.nanolett.2c01316","article-title":"Defined positive charge patterns created on DNA nanostructures determine cellular uptake efficiency","volume":"22","author":"Shi","year":"2022","journal-title":"Nano Lett."},{"key":"10.1016\/j.actbio.2024.12.026_bib0041","article-title":"Development of sulfonamide-functionalized charge-reversal AIE photosensitizers for precise photodynamic therapy in the acidic tumor microenvironment","volume":"33","author":"Yang","year":"2023","journal-title":"Adv. Funct. Mater."},{"issue":"10","key":"10.1016\/j.actbio.2024.12.026_bib0042","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.3390\/pharmaceutics13101686","article-title":"Chitosan nanoparticles at the biological interface: implications for drug delivery","volume":"13","author":"Aibani","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.actbio.2024.12.026_bib0043","first-page":"0148","article-title":"Advanced strategies for overcoming endosomal\/lysosomal barrier in nanodrug delivery","volume":"6","author":"Qiu","year":"2023","journal-title":"Research (Washington, D.C.)"},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0044","doi-asserted-by":"crossref","first-page":"6645","DOI":"10.1038\/s41467-023-42280-9","article-title":"Nanomechanical action opens endo-lysosomal compartments","volume":"14","author":"Zhao","year":"2023","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.actbio.2024.12.026_bib0045","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.bbrc.2012.03.121","article-title":"Hydrogen sulfide decreases the levels of ROS by inhibiting mitochondrial complex IV and increasing SOD activities in cardiomyocytes under ischemia\/reperfusion","volume":"421","author":"Sun","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0046","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.3390\/ijms25031755","article-title":"From acute to chronic: unraveling the pathophysiological mechanisms of the progression from acute kidney injury to acute kidney disease to chronic kidney disease","volume":"25","author":"Yeh","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"41","key":"10.1016\/j.actbio.2024.12.026_bib0047","doi-asserted-by":"crossref","first-page":"eabb7422","DOI":"10.1126\/sciadv.abb7422","article-title":"ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule","volume":"6","author":"Liu","year":"2020","journal-title":"Sci. Adv."},{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0048","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1124\/jpet.121.000667","article-title":"Kidney-targeted delivery of prolyl hydroxylase domain protein 2 small interfering RNA with nanoparticles alleviated renal ischemia\/reperfusion injury","volume":"378","author":"Xie","year":"2021","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.actbio.2024.12.026_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119643","article-title":"Renal clearance of polymeric nanoparticles by mimicry of glycan surface of viruses","volume":"230","author":"Wyss","year":"2020","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.actbio.2024.12.026_bib0050","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1021\/nl504610d","article-title":"Mesoscale nanoparticles selectively target the renal proximal tubule epithelium","volume":"15","author":"Williams","year":"2015","journal-title":"Nano Lett."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0051","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/HYPERTENSIONAHA.117.09843","article-title":"Selective nanoparticle targeting of the renal tubules","volume":"71","author":"Williams","year":"2018","journal-title":"Hypertension (Dallas, Tex.: 1979)"},{"issue":"6","key":"10.1016\/j.actbio.2024.12.026_bib0052","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.2215\/CJN.02070606","article-title":"Defining acute renal failure: RIFLE and beyond","volume":"1","author":"Van Biesen","year":"2006","journal-title":"Clin. J. Am. Soc. Nephrol.: CJASN"},{"issue":"3","key":"10.1016\/j.actbio.2024.12.026_bib0053","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00134-006-0478-x","article-title":"Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria","volume":"33","author":"Bellomo","year":"2007","journal-title":"Intensive Care Med."},{"issue":"5","key":"10.1016\/j.actbio.2024.12.026_bib0054","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.phymed.2012.12.001","article-title":"Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage","volume":"20","author":"Sahu","year":"2013","journal-title":"Phytomed.: Int. J. Phytother. Phytopharmacol."},{"key":"10.1016\/j.actbio.2024.12.026_bib0055","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.3389\/fimmu.2018.02246","article-title":"ADGRE1 (EMR1, F4\/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages","volume":"9","author":"Waddell","year":"2018","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.actbio.2024.12.026_bib0056","doi-asserted-by":"crossref","first-page":"e22630","DOI":"10.1002\/jbt.22630","article-title":"Curcumin alleviates acute kidney injury in a dry-heat environment by reducing oxidative stress and inflammation in a rat model","volume":"35","author":"Zhao","year":"2021","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"2","key":"10.1016\/j.actbio.2024.12.026_bib0057","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","article-title":"Ferroptosis: past, present and future","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.actbio.2024.12.026_bib0058","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1038\/srep02233","article-title":"H2O2-responsive molecularly engineered polymer nanoparticles as ischemia\/reperfusion-targeted nanotherapeutic agents","volume":"3","author":"Lee","year":"2013","journal-title":"Sci. Rep."},{"issue":"48","key":"10.1016\/j.actbio.2024.12.026_bib0059","doi-asserted-by":"crossref","first-page":"1904833","DOI":"10.1002\/adfm.201904833","article-title":"A melanin-based natural antioxidant defense nanosystem for theranostic application in acute kidney injury","volume":"29","author":"Sun","year":"2019","journal-title":"Adv. Funct. Mater."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124007359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706124007359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T22:59:46Z","timestamp":1762556386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706124007359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":59,"alternative-id":["S1742706124007359"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2024.12.026","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lysozyme-targeted liposomes for enhanced tubular targeting in the treatment of acute kidney injury","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2024.12.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Acta Materialia Inc. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}