{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:12:53Z","timestamp":1791861173957,"version":"4.3.4"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2023SCUH0012"],"award-info":[{"award-number":["2023SCUH0012"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2402801"],"award-info":[{"award-number":["2022YFC2402801"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2025ZNSFSC1711"],"award-info":[{"award-number":["2025ZNSFSC1711"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2025ZNSFSC0247"],"award-info":[{"award-number":["2025ZNSFSC0247"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52373150"],"award-info":[{"award-number":["52373150"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52303195"],"award-info":[{"award-number":["52303195"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82403838"],"award-info":[{"award-number":["82403838"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32361133548"],"award-info":[{"award-number":["32361133548"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.actbio.2025.05.054","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T19:08:28Z","timestamp":1748027308000},"page":"198-211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Bovine amniotic membrane with antioxidant and anti-inflammatory properties for the repair of alkali-burned corneas"],"prefix":"10.1016","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9965-9635","authenticated-orcid":false,"given":"Mengna","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3812-9208","authenticated-orcid":false,"given":"Hongsong","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2025.05.054_bib0001","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/bs.pmbts.2015.04.001","article-title":"Overview of the cornea: structure, function, and development, Prog","volume":"134","author":"Eghrari","year":"2015","journal-title":"Mol. Biol. Transl. Sci."},{"key":"10.1016\/j.actbio.2025.05.054_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.07.001","article-title":"Corneal structure and transparency","volume":"49","author":"Meek","year":"2015","journal-title":"Prog. Retin. Eye Res."},{"issue":"2","key":"10.1016\/j.actbio.2025.05.054_bib0003","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","article-title":"Global survey of corneal transplantation and eye banking","volume":"134","author":"Gain","year":"2016","journal-title":"JAMa Ophthalmol."},{"issue":"4","key":"10.1016\/j.actbio.2025.05.054_bib0004","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/s41433-023-02777-5","article-title":"Amniotic membrane transplantation: structural and biological properties, tissue preparation, application and clinical indications","volume":"38","author":"Sanders","year":"2024","journal-title":"Eye"},{"issue":"9","key":"10.1016\/j.actbio.2025.05.054_bib0005","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.3390\/pharmaceutics15092249","article-title":"Human acellular amniotic membrane as skin substitute and biological scaffold: a review of its preparation, preclinical research, and clinical application","volume":"15","author":"Li","year":"2023","journal-title":"Pharmaceutics."},{"issue":"12","key":"10.1016\/j.actbio.2025.05.054_bib0006","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1136\/bjo.85.12.1455","article-title":"Single and multilayer amniotic membrane transplantation for persistent corneal epithelial defect with and without stromal thinning and perforation","volume":"85","author":"Prabhasawat","year":"2001","journal-title":"Br. J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.actbio.2025.05.054_bib0007","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.biomaterials.2009.09.034","article-title":"Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction","volume":"31","author":"Riau","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2025.05.054_bib0008","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2020.599800","article-title":"Heparin-modified amniotic membrane combined with growth factors for promoting corneal wound healing after alkali burn","volume":"8","author":"Zhao","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"7","key":"10.1016\/j.actbio.2025.05.054_bib0009","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1021\/acsbiomaterials.8b00015","article-title":"Human amniotic membrane: a versatile scaffold for tissue engineering","volume":"4","author":"Arrizabalaga","year":"2018","journal-title":"ACS. Biomater. Sci. Eng."},{"key":"10.1016\/j.actbio.2025.05.054_bib0010","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.actbio.2019.08.027","article-title":"Nanofiber-reinforced decellularized amniotic membrane improves limbal stem cell transplantation in a rabbit model of corneal epithelial defect","volume":"97","author":"Zhou","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.05.054_bib0011","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.2147\/IJN.S52731","article-title":"Glutaraldehyde cross-linking of amniotic membranes affects their nanofibrous structures and limbal epithelial cell culture characteristics","volume":"8","author":"Lai","year":"2013","journal-title":"Int. J. Nanomed."},{"issue":"2","key":"10.1016\/j.actbio.2025.05.054_bib0012","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jtos.2013.01.002","article-title":"Corneal crosslinking with riboflavin and ultraviolet A. I. Principles","volume":"11","author":"Raiskup","year":"2013","journal-title":"Ocul. Surf."},{"issue":"2","key":"10.1016\/j.actbio.2025.05.054_bib0013","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3390\/jfb6020277","article-title":"Nanomedicine approaches for corneal diseases","volume":"6","author":"Chaurasia","year":"2015","journal-title":"J. Funct. Biomater."},{"issue":"2","key":"10.1016\/j.actbio.2025.05.054_bib0014","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.survophthal.2017.09.005","article-title":"Treatment of acute ocular chemical burns","volume":"63","author":"Sharma","year":"2018","journal-title":"Surv. Ophthalmol."},{"issue":"5","key":"10.1016\/j.actbio.2025.05.054_bib0015","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.burns.2019.11.007","article-title":"Ocular chemical burns in the workplace: epidemiological characteristics","volume":"46","author":"Quesada","year":"2020","journal-title":"Burns"},{"issue":"8","key":"10.1016\/j.actbio.2025.05.054_bib0016","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0305-4179(00)00044-9","article-title":"Eye burns: an emergency and continuing problem","volume":"26","author":"Schrage","year":"2000","journal-title":"Burns"},{"issue":"11","key":"10.1016\/j.actbio.2025.05.054_bib0017","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1038\/s41433-020-1026-6","article-title":"Chemical eye injury: pathophysiology, assessment and management","volume":"34","author":"Dua","year":"2020","journal-title":"Eye (Lond. U. K.)"},{"key":"10.1016\/j.actbio.2025.05.054_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108539","article-title":"PLGA nanoparticles containing Lingzhi extracts rescue corneal epithelial cells from oxidative damage","volume":"206","author":"Tsai","year":"2021","journal-title":"Exp. Eye. Res."},{"issue":"1","key":"10.1016\/j.actbio.2025.05.054_bib0019","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jtos.2016.09.002","article-title":"Current and upcoming therapies for ocular surface chemical injurie","volume":"15","author":"Baradaran-Rafii","year":"2017","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.actbio.2025.05.054_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101269","article-title":"Nanozymes: a clear definition with fuzzy edges","volume":"40","author":"Wei","year":"2021","journal-title":"Nano. Today"},{"issue":"14","key":"10.1016\/j.actbio.2025.05.054_bib0021","doi-asserted-by":"crossref","first-page":"6060","DOI":"10.1039\/c3cs35486e","article-title":"Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes","volume":"42","author":"Wei","year":"2013","journal-title":"Chem. Soc. Rev."},{"issue":"10","key":"10.1016\/j.actbio.2025.05.054_bib0022","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202211151","article-title":"Reaction mechanisms and kinetics of nanozymes: insights from theory and computation","volume":"36","author":"Shen","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.actbio.2025.05.054_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.142338","article-title":"Carbon dots as potential antioxidants for the scavenging of multi-reactive oxygen and nitrogen species","volume":"462","author":"Gao","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.actbio.2025.05.054_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113483","article-title":"Catalase application in cancer therapy: Simultaneous focusing on hypoxia attenuation and macrophage reprogramming","volume":"153","author":"Najafi","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"35","key":"10.1016\/j.actbio.2025.05.054_bib0025","doi-asserted-by":"crossref","first-page":"6939","DOI":"10.1039\/D1TB00720C","article-title":"Superoxide dismutase nanozymes: an emerging star for anti-oxidation","volume":"9","author":"Zhao","year":"2021","journal-title":"J. Mater. Chem. B"},{"issue":"4","key":"10.1016\/j.actbio.2025.05.054_bib0026","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1021\/acsmaterialslett.4c00109","article-title":"EDTA-functionalized carbon dots\u2013metal nanozymes based on coordination chemistry: species of metal ions determines enzyme-mimicking catalyzed activities","volume":"6","author":"Dong","year":"2024","journal-title":"ACS Mater. Lett."},{"key":"10.1016\/j.actbio.2025.05.054_bib0027","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.nanoen.2018.03.063","article-title":"Graphene quantum dot engineered nickel-cobalt phosphide as highly efficient bifunctional catalyst for overall water splitting","volume":"48","author":"Tian","year":"2018","journal-title":"Nano. Energy"},{"key":"10.1016\/j.actbio.2025.05.054_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.133101","article-title":"Metal ions-doped carbon dots: synthesis, properties, and applications","volume":"430","author":"Li","year":"2022","journal-title":"Chem, Eng. J."},{"issue":"1","key":"10.1016\/j.actbio.2025.05.054_bib0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.33549\/physiolres.930398","article-title":"UV Rays, the prooxidant\/antioxidant imbalance in the cornea and oxidative eye damage","volume":"53","author":"Cejkov\u00e1","year":"2004","journal-title":"Physiol. Res."},{"key":"10.1016\/j.actbio.2025.05.054_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108539","article-title":"PLGA nanoparticles containing Lingzhi extracts rescue corneal epithelial cells from oxidative damage","volume":"206","author":"Tsai","year":"2021","journal-title":"Exp. Eye Res."},{"issue":"15","key":"10.1016\/j.actbio.2025.05.054_bib0031","doi-asserted-by":"crossref","first-page":"17022","DOI":"10.1021\/acsami.1c23412","article-title":"Reactive oxygen species-responsive lipid nanoparticles for effective RNAi and corneal neovascularization therapy","volume":"14","author":"Liu","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"5","key":"10.1016\/j.actbio.2025.05.054_bib0032","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202407606","article-title":"Glycerol modulated collagen fibril evolution and lamellar organization for biomimetic corneal substitutes construction","volume":"21","author":"Wu","year":"2024","journal-title":"Small."},{"key":"10.1016\/j.actbio.2025.05.054_bib0033","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.ijbiomac.2018.12.125","article-title":"Preparation and in vitro characterization of cross-linked collagen-gelatin hydrogel using EDC\/NHS for corneal tissue engineering applications","volume":"126","author":"Goodarzi","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2025.05.054_bib0034","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.msec.2015.05.030","article-title":"Collagen based film with well epithelial and stromal regeneration as corneal repair materials: improving mechanical property by crosslinking with citric acid","volume":"55","author":"Zhao","year":"2015","journal-title":"Mater. Sci. Eng. C"},{"issue":"8","key":"10.1016\/j.actbio.2025.05.054_bib0035","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202414895","article-title":"Elucidating manganese single-atom doping: strategies for fluorescence enhancement in water-soluble red-emitting carbon dots and applications for FL\/MR dual mode imaging","volume":"12","author":"Gao","year":"2025","journal-title":"Adv. Sci."},{"issue":"19","key":"10.1016\/j.actbio.2025.05.054_bib0036","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202313248","article-title":"Catalytic nanodots-driven pyroptosis suppression in nucleus pulposus for antioxidant intervention of intervertebral disc degeneration","volume":"36","author":"Sun","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.actbio.2025.05.054_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122449","article-title":"Mitochondrial-targeting and NIR-responsive Mn3O4@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis","volume":"305","author":"Li","year":"2024","journal-title":"Biomaterials"},{"issue":"23","key":"10.1016\/j.actbio.2025.05.054_bib0038","article-title":"Facet-dependent biodegradable Mn3O4 nanoparticles for ameliorating Parkinson's disease","volume":"10","author":"Xu","year":"2021","journal-title":"Adv. Heal. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2025.05.054_bib0039","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1167\/iovs.10-6167","article-title":"Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model","volume":"52","author":"Kubota","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.actbio.2025.05.054_bib0040","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.jcis.2021.12.107","article-title":"Carbon dots as nanocatalytic medicine for anti-inflammation therapy","volume":"611","author":"Kong","year":"2022","journal-title":"Colloid Interface Sci."},{"issue":"39","key":"10.1016\/j.actbio.2025.05.054_bib0041","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202100176","article-title":"Rational design of i mMunomodulatory hydrogels for chronic wound healing","volume":"33","author":"Kharaziha","year":"2021","journal-title":"Adv. Mater."},{"issue":"12","key":"10.1016\/j.actbio.2025.05.054_bib0042","doi-asserted-by":"crossref","first-page":"8549","DOI":"10.1167\/iovs.11-7956","article-title":"Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing","volume":"52","author":"Ebihara","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"8","key":"10.1016\/j.actbio.2025.05.054_bib0043","first-page":"1047","article-title":"Oxidative stress in diseases of the human cornea, Free Radic","volume":"45","author":"Shoham","year":"2008","journal-title":"Biol. Med."},{"issue":"13","key":"10.1016\/j.actbio.2025.05.054_bib0044","doi-asserted-by":"crossref","first-page":"7989","DOI":"10.1167\/iovs.12-10658","article-title":"Inhibition of choroidal and corneal pathologic neovascularization by Plgf1-de gene transfer","volume":"53","author":"Tarallo","year":"2012","journal-title":"Invest. Ophthalmol. Vis Sci."},{"issue":"5","key":"10.1016\/j.actbio.2025.05.054_bib0045","first-page":"341","article-title":"Sutureless amniotic membrane ProKera for ocular surface disorders: short-term results","volume":"39","author":"Suri","year":"2013","journal-title":"Contact Lens Assoc. Ophthalmol. J."},{"issue":"13","key":"10.1016\/j.actbio.2025.05.054_bib0046","first-page":"4707","article-title":"Sutureless amniotic membrane transplantation for ocular surface disorders: a comparison of Prokera to AmbioDisc","volume":"55","author":"Giannikas","year":"2014","journal-title":"Invest, Ophthalmol. Vis. Sci."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706125003794?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706125003794?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:25:54Z","timestamp":1778624754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706125003794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":46,"alternative-id":["S1742706125003794"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2025.05.054","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bovine amniotic membrane with antioxidant and anti-inflammatory properties for the repair of alkali-burned corneas","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2025.05.054","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Acta Materialia Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}