{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T10:40:54Z","timestamp":1774003254051,"version":"3.50.1"},"reference-count":95,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,2,23]],"date-time":"2027-02-23T00:00:00Z","timestamp":1803340800000},"content-version":"am","delay-in-days":359,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["144\\u2013532905-AAK6656-4"],"award-info":[{"award-number":["144\\u2013532905-AAK6656-4"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007923","name":"University of Wisconsin-Madison Carbone Cancer Center","doi-asserted-by":"publisher","award":["P30 CA014520"],"award-info":[{"award-number":["P30 CA014520"]}],"id":[{"id":"10.13039\/100007923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["S10 OD023526"],"award-info":[{"award-number":["S10 OD023526"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005902","name":"University of Wisconsin-Madison Institute for Clinical and Translational Research","doi-asserted-by":"publisher","award":["144\\u2013532905-AAK6656-4"],"award-info":[{"award-number":["144\\u2013532905-AAK6656-4"]}],"id":[{"id":"10.13039\/100005902","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.actbio.2026.01.030","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T16:24:28Z","timestamp":1768494268000},"page":"481-495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Structural and mechanical analysis of treated and untreated aortic coarctation in a growing porcine model"],"prefix":"10.1016","volume":"212","author":[{"given":"Matthew A.","family":"Culver","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0682-6714","authenticated-orcid":false,"given":"Michael A.","family":"Stellon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0590-8856","authenticated-orcid":false,"given":"Leah M.","family":"Gober","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3481-7483","authenticated-orcid":false,"given":"Sudhindra","family":"Chavadam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2769-8835","authenticated-orcid":false,"given":"Dana","family":"Irrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Lamers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4149-4038","authenticated-orcid":false,"given":"Alejandro","family":"Rold\u00e1n-Alzate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9117-4422","authenticated-orcid":false,"given":"Colleen M.","family":"Witzenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2026.01.030_bib0001","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/bdr2.1589","article-title":"National population-based estimates for major birth defects, 2010\u20132014","volume":"111","author":"Mai","year":"2019","journal-title":"Birth Defects Res."},{"key":"10.1016\/j.actbio.2026.01.030_bib0002","doi-asserted-by":"crossref","DOI":"10.1007\/s11936-014-0341-2","article-title":"Coarctation of the aorta: management, indications for intervention, and advances in care","volume":"16","author":"Usman","year":"2014","journal-title":"Curr. Treat. Options. Cardiovasc. Med."},{"key":"10.1016\/j.actbio.2026.01.030_bib0003","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1136\/heartjnl-2017-311173","article-title":"Diagnosis, imaging and clinical management of aortic coarctation","volume":"103","author":"Dijkema","year":"2017","journal-title":"Heart."},{"key":"10.1016\/j.actbio.2026.01.030_bib0004","doi-asserted-by":"crossref","first-page":"H1117","DOI":"10.1152\/ajpheart.00087.2024","article-title":"Surgically induced aortic coarctation in a neonatal porcine model allows for longitudinal assessment of cardiovascular changes","volume":"326","author":"Stellon","year":"2024","journal-title":"Am. J. Physiol. Heart. Circ. Physiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0005","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1136\/hrt.32.5.633","article-title":"Natural history of coarctation of the aorta","volume":"32","author":"Campbell","year":"1970","journal-title":"Heart."},{"key":"10.1016\/j.actbio.2026.01.030_bib0006","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA Guideline for the Diagnosis and Management of aortic disease: a report of the American Heart Association\/American College of Cardiology Joint Committee on Clinical Practice Guidelines","volume":"146","author":"Isselbacher","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2026.01.030_bib0007","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000137697","article-title":"Mortality and restenosis rate of surgical coarctation repair in infancy: a study of 191 patients","volume":"112","author":"Hager","year":"2009","journal-title":"Cardiology"},{"key":"10.1016\/j.actbio.2026.01.030_bib0008","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1136\/hrt.2004.058685","article-title":"Outcome after extended arch repair for aortic coarctation","volume":"92","author":"Thomson","year":"2006","journal-title":"Heart."},{"key":"10.1016\/j.actbio.2026.01.030_bib0009","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1583\/08-2436.1","article-title":"TEVAR in patients with late complications of aortic coarctation repair","volume":"15","author":"Midulla","year":"2008","journal-title":"J. Endovasc. Ther."},{"key":"10.1016\/j.actbio.2026.01.030_bib0010","first-page":"117","article-title":"Preliminary testing and evaluation of the renata minima stent, an infant stent capable of achieving adult dimensions","volume":"98","author":"Zahn","year":"2021","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"10.1016\/j.actbio.2026.01.030_bib0011","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.122.012697","article-title":"Evolving utilization of covered stents for treatment of aortic coarctation: report from the IMPACT Registry","volume":"16","author":"Morray","year":"2023","journal-title":"Circ. Cardiovasc. Interv."},{"key":"10.1016\/j.actbio.2026.01.030_bib0012","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s00246-023-03402-8","article-title":"Medium-term outcomes of stent therapy for aortic coarctation in children under 30 kg with new generation low-profile stents: a follow-up study of a single centre experience","volume":"45","author":"Gibb","year":"2024","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0013","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.121.010576","article-title":"Large diameter Advanta V12 covered stent trial for coarctation of the aorta: COARC study","volume":"14","author":"Bruckheimer","year":"2021","journal-title":"Circ. Cardiovasc. Interv."},{"key":"10.1016\/j.actbio.2026.01.030_bib0014","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/hr.2011.22","article-title":"Hypertension and coarctation of the aorta: an inevitable consequence of developmental pathophysiology","volume":"34","author":"Kenny","year":"2011","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.actbio.2026.01.030_bib0015","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.atherosclerosis.2005.01.030","article-title":"Evidence of vascular dysfunction in young patients with successfully repaired coarctation of aorta","volume":"182","author":"Brili","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.actbio.2026.01.030_bib0016","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ijcard.2004.02.001","article-title":"Vascular dysfunction after coarctation repair is related to the age at surgery","volume":"99","author":"Heger","year":"2005","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0017","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/s41371-021-00585-6","article-title":"Multi-centre cross-sectional study on vascular remodelling in children following successful coarctation correction","volume":"36","author":"Sendzikaite","year":"2022","journal-title":"J. Hum. Hypertens."},{"key":"10.1016\/j.actbio.2026.01.030_bib0018","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijcard.2017.05.075","article-title":"Elevated sympathetic activity, endothelial dysfunction, and late hypertension after repair of coarctation of the aorta","volume":"243","author":"Lee","year":"2017","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0019","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1016\/j.ijcard.2012.09.084","article-title":"Hypertension after repair of aortic coarctation - a systematic review","volume":"167","author":"Canniffe","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0020","doi-asserted-by":"crossref","unstructured":"O.H. Toro-Salazar, J. Steinberger, W. Thomas, A.P. Rocchini, B. Carpenter, J.H. Moller, Long-term follow-up of patients after coarctation of the aorta repair, 2002.","DOI":"10.1016\/S0002-9149(01)02293-7"},{"key":"10.1016\/j.actbio.2026.01.030_bib0021","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/0002-9149(83)90661-6","article-title":"Results after repair of coarctation of the aorta beyond infancy: a 10 to 28 year follow-up with particular reference to late systemic hypertension","volume":"51","author":"Clarkson","year":"1983","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0022","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1161\/01.CIR.80.4.840","article-title":"Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction","volume":"80","author":"Cohen","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2026.01.030_bib0023","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0021-9290(01)00043-4","article-title":"Limitations of Doppler echocardiography for the post-operative evaluation of aortic coarctation","volume":"34","author":"De Mey","year":"2001","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0024","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1136\/hrt.18.4.475","article-title":"The course and prognosis of coarctation of the aorta","volume":"18","author":"Campbell","year":"1956","journal-title":"Heart."},{"key":"10.1016\/j.actbio.2026.01.030_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmpb.2020.105522","article-title":"Analysis of the formation mechanism and occurrence possibility of post-stenotic dilatation of the aorta by CFD approach","volume":"194","author":"Zhang","year":"2020","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/j.actbio.2026.01.030_bib0026","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1161\/01.CIR.65.6.1060","article-title":"Different reactivity and structure of the prestenotic and poststenotic aorta in human coarctation. Implications for baroreceptor function","volume":"65","author":"Sehested","year":"1982","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2026.01.030_bib0027","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/path.1700780122","article-title":"Histology of the aorta in coarctation","volume":"78","author":"Dunnill","year":"1959","journal-title":"J. Pathol. Bacteriol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0028","first-page":"835","article-title":"Pathogenesis and significance of post-stenotic dilatation in great vessels","volume":"147","author":"Robicsek","year":"1958","journal-title":"Ann. Surg."},{"key":"10.1016\/j.actbio.2026.01.030_bib0029","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000166341","article-title":"On the origin of poststenotic dilatations","volume":"33","author":"de Vries","year":"1958","journal-title":"Cardiology"},{"key":"10.1016\/j.actbio.2026.01.030_bib0030","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ahj.2018.04.004","article-title":"Arterioventricular interaction after coarctation repair","volume":"201","author":"Dijkema","year":"2018","journal-title":"Am. Heart. J."},{"key":"10.1016\/j.actbio.2026.01.030_bib0031","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1378\/chest.102.4.1193","article-title":"Does radial artery pressure accurately reflect aortic pressure?","volume":"102","author":"Pauca","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.actbio.2026.01.030_bib0032","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jss.2017.05.053","article-title":"Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation","volume":"218","author":"Wendell","year":"2017","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.actbio.2026.01.030_bib0033","article-title":"Characterizing the mechanical properties of the aortic wall","volume":"3","author":"Pejcic","year":"2019","journal-title":"Vessel. Plus."},{"key":"10.1016\/j.actbio.2026.01.030_bib0034","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1748-1716.2006.01661.x","article-title":"Passive mechanical properties and structure of the aorta: segmental analysis","volume":"190","author":"Sokolis","year":"2007","journal-title":"Acta Physiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0035","article-title":"The mechanical characterization of blood vessels and their substitutes in the continuous quest for physiological-relevant performances. A critical review","volume":"10","author":"Camas\u00e3o","year":"2021","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.actbio.2026.01.030_bib0036","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1098\/rsif.2006.0138","article-title":"Biomechanics of the cardiovascular system: the aorta as an illustratory example","volume":"3","author":"Kassab","year":"2006","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.actbio.2026.01.030_bib0037","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.athoracsur.2015.07.028","article-title":"Is there a role for biomechanical engineering in helping to elucidate the risk profile of the thoracic aorta?","volume":"101","author":"Martufi","year":"2016","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.actbio.2026.01.030_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.pmatsci.2024.101363","article-title":"Mechanisms of aortic dissection: from pathological changes to experimental and in silico models","volume":"150","author":"Rolf-Pissarczyk","year":"2025","journal-title":"Prog. Mater. Sci."},{"key":"10.1016\/j.actbio.2026.01.030_bib0039","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jmbbm.2015.05.024","article-title":"Layer-specific residual deformations and uniaxial and biaxial mechanical properties of thoracic porcine aorta","volume":"50","author":"Pe\u00f1a","year":"2015","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2026.01.030_bib0040","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1115\/1.4026443","article-title":"Prefailure and failure mechanics of the porcine ascending thoracic aorta: experiments and a multiscale model","volume":"136","author":"Shah","year":"2014","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0041","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1115\/1.4035264","article-title":"Failure of the Porcine ascending Aorta: multidirectional experiments and a unifying model","volume":"139","author":"Witzenburg","year":"2017","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0042","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics13132189","article-title":"Coarctation of the aorta: diagnosis and management","volume":"13","author":"Raza","year":"2023","journal-title":"Diagnostics"},{"key":"10.1016\/j.actbio.2026.01.030_bib0043","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0021-9290(87)90268-5","article-title":"Factors in the propagation of aortic dissections in canine thoracic aortas","volume":"20","author":"van Baardwijk","year":"1987","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0044","doi-asserted-by":"crossref","DOI":"10.1115\/1.2898733","article-title":"Dissection properties of the human aortic media: an experimental study","volume":"130","author":"Sommer","year":"2008","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0045","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1007\/s10439-011-0264-y","article-title":"Dissection properties and mechanical strength of tissue components in human carotid bifurcations","volume":"39","author":"Tong","year":"2011","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0046","doi-asserted-by":"crossref","first-page":"3820","DOI":"10.1016\/j.jbiomech.2014.10.024","article-title":"Effect of aneurysm on biomechanical properties of \u201cradially-oriented\u201d collagen fibers in human ascending thoracic aortic media","volume":"47","author":"Tsamis","year":"2014","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0047","doi-asserted-by":"crossref","first-page":"229","DOI":"10.15632\/jtam-pl.54.1.229","article-title":"Delamination properties of the human thoracic arterial wall with early stage of atherosclerosis lesions","volume":"54","author":"Kozu\u0144","year":"2016","journal-title":"J. Theor. Appl. Mech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0048","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jbiomech.2010.08.031","article-title":"Novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc","volume":"44","author":"Gregory","year":"2011","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0049","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10237-009-0184-z","article-title":"A 3-D constrained mixture model for mechanically mediated vascular growth and remodeling","volume":"9","author":"Wan","year":"2010","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0050","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1016\/j.cma.2008.09.013","article-title":"A computational framework for fluid-solid-growth modeling in cardiovascular simulations","volume":"198","author":"Alberto Figueroa","year":"2009","journal-title":"Comput. Methods Appl. Mech. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0051","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1152\/ajpheart.00444.2004","article-title":"Adaptation to mechanical load determines shape and properties of heart and circulation: the CircAdapt model","volume":"288","author":"Arts","year":"2005","journal-title":"Am. J. Physiol. Heart. Circ. Physiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0052","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1136\/heartjnl-2014-305739","article-title":"Endothelial function in contemporary patients with repaired coarctation of aorta","volume":"100","author":"Radke","year":"2014","journal-title":"Heart."},{"key":"10.1016\/j.actbio.2026.01.030_bib0053","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1161\/HYPERTENSIONAHA.115.06262","article-title":"Excessive adventitial remodeling leads to early aortic maladaptation in angiotensin-induced hypertension","volume":"67","author":"Bersi","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.actbio.2026.01.030_bib0054","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jmbbm.2014.04.015","article-title":"The impact of long term freezing on the mechanical properties of porcine aortic tissue","volume":"37","author":"O\u2019Leary","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2026.01.030_bib0055","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jss.2006.09.001","article-title":"Mechanics of fresh, refrigerated, and frozen arterial tissue","volume":"139","author":"Stemper","year":"2007","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.actbio.2026.01.030_bib0056","doi-asserted-by":"crossref","first-page":"645","DOI":"10.4236\/jbise.2010.37088","article-title":"Effect of freezing on the passive mechanical properties of arterial samples","volume":"03","author":"Virues Delgadillo","year":"2010","journal-title":"J. Biomed. Sci. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0057","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1007\/s10439-011-0506-z","article-title":"Characterization of changes to the mechanical properties of arteries due to cold storage using nanoindentation tests","volume":"40","author":"Hemmasizadeh","year":"2012","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0058","doi-asserted-by":"crossref","DOI":"10.1002\/cpz1.493","article-title":"Combining unique planar biaxial testing with full-field thickness and displacement measurement for spatial characterization of soft tissues","volume":"2","author":"Pearce","year":"2022","journal-title":"Curr. Protoc."},{"key":"10.1016\/j.actbio.2026.01.030_bib0059","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.actbio.2017.04.011","article-title":"Investigating mechanisms of tendon damage by measuring multi-scale recovery following tensile loading","volume":"57","author":"Lee","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2026.01.030_bib0060","unstructured":"R. Rahupathy, V. Barocas, Robust Image Correlation Based Strain Calculator for Tissue Systems (20130022, Dr. Victor Barocas), https:\/\/license.umn.edu\/product\/robust-image-correlation-based-strain-calculator-for-tissue-systems (2013)."},{"key":"10.1016\/j.actbio.2026.01.030_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2012.08.104","article-title":"Coarctation-induced degenerative abdominal aortic aneurysm in a porcine model","volume":"57","author":"Lin","year":"2013","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.actbio.2026.01.030_bib0062","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.vascn.2011.10.003","article-title":"A coupled experimental and computational approach to quantify deleterious hemodynamics, vascular alterations, and mechanisms of long-term morbidity in response to aortic coarctation","volume":"65","author":"Menon","year":"2012","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.actbio.2026.01.030_bib0063","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1152\/ajpheart.00420.2012","article-title":"Altered hemodynamics, endothelial function, and protein expression occur with aortic coarctation and persist after repair","volume":"303","author":"Menon","year":"2012","journal-title":"Am. J. Physiol. Heart. Circ. Physiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0064","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-34400-8","article-title":"Temporal evolution of mechanical stimuli from vascular remodeling in response to the severity and duration of aortic coarctation in a preclinical model","volume":"13","author":"Azarnoosh","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2026.01.030_bib0065","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1369\/jhc.7A7324.2007","article-title":"Time courses of growth and remodeling of porcine aortic media during hypertension: a quantitative immunohistochemical examination","volume":"56","author":"Hu","year":"2008","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.actbio.2026.01.030_bib0066","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000025728","article-title":"Differential transmural distribution of gene expression for collagen types I and III proximal to aortic coarctation in the rabbit","volume":"37","author":"Xu","year":"2000","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.actbio.2026.01.030_bib0067","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1006\/exmp.2002.2423","article-title":"Gene expression of tropoelastin is enhanced in the aorta proximal to the coarctation in rabbits","volume":"72","author":"Xu","year":"2002","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0068","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1109\/TBME.2022.3207060","article-title":"High-frequency fluctuation intensity as a predictor of post-stenotic dilatation in swine","volume":"70","author":"Lin","year":"2023","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0069","doi-asserted-by":"crossref","unstructured":"C.E. Korenczuk, K.K. Liao, V.H. Barocas, Ex vivo mechanical tests and multiscale computational modeling highlight the importance of intramural shear stress in ascending thoracic aortic aneurysms, 141 (2019) 1\u201311. https:\/\/doi.org\/10.1115\/1.4045270.","DOI":"10.1115\/1.4045270"},{"key":"10.1016\/j.actbio.2026.01.030_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-92659-1","article-title":"Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components","volume":"11","author":"Yousef","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2026.01.030_bib0071","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.matbio.2007.10.008","article-title":"The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging","volume":"27","author":"O\u2019Connell","year":"2008","journal-title":"Matrix Biol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0072","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0741-5214(99)70317-4","article-title":"The role of radial elastic properties in the development of aortic dissections","volume":"29","author":"MacLean","year":"1999","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.actbio.2026.01.030_bib0073","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2025.112500","article-title":"What about the mechanical behaviour and modelling of arteries in radial direction?","volume":"182","author":"R\u00edos-Ru\u00edz","year":"2025","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0074","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s13239-021-00554-7","article-title":"Failure properties of healthy and diabetic rabbit thoracic aortas and their potential correlation with mass fractions of collagen","volume":"13","author":"Tong","year":"2022","journal-title":"Cardiovasc. Eng. Technol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0075","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1109\/RBME.2019.2950140","article-title":"Review of current advances in the mechanical description and quantification of aortic dissection mechanisms","volume":"14","author":"Brunet","year":"2021","journal-title":"IEEe Rev. Biomed. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0076","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11340-020-00641-1","article-title":"In vitro measurement of strain localization preceding dissection of the aortic wall subjected to radial tension","volume":"61","author":"Di Giuseppe","year":"2021","journal-title":"Exp. Mech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0077","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actbio.2019.08.017","article-title":"Biomechanics of aortic wall failure with a focus on dissection and aneurysm: a review","volume":"99","author":"Sherifova","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2026.01.030_bib0078","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10237-020-01370-z","article-title":"Mechanical and structural contributions of elastin and collagen fibers to interlamellar bonding in the arterial wall","volume":"20","author":"Wang","year":"2021","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0079","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1016\/j.jbiomech.2006.10.025","article-title":"Mechanical properties of elastin along the thoracic aorta in the pig","volume":"40","author":"Lillie","year":"2007","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2026.01.030_bib0080","first-page":"1551","article-title":"Constitutive modelling of arteries, proceedings of the royal society A: mathematical","volume":"466","author":"Holzapfel","year":"2010","journal-title":"Phys. Eng. Sci."},{"key":"10.1016\/j.actbio.2026.01.030_bib0081","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1098\/rsif.2005.0073","article-title":"Hyperelastic modelling of arterial layers with distributed collagen fibre orientations","volume":"3","author":"Gasser","year":"2006","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.actbio.2026.01.030_bib0082","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s10558-006-9021-5","article-title":"Elastic and rupture properties of porcine aortic tissue measured using inflation testing","volume":"6","author":"Marra","year":"2006","journal-title":"Cardiovasc. Eng."},{"key":"10.1016\/j.actbio.2026.01.030_bib0083","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11071817","article-title":"Aortic remodeling kinetics in response to coarctation-induced mechanical perturbations","volume":"11","author":"Ghorbannia","year":"2023","journal-title":"Biomedicines."},{"key":"10.1016\/j.actbio.2026.01.030_bib0084","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.matbio.2019.08.005","article-title":"Rise and fall of elastic fibers from development to aging. Consequences on arterial structure-function and therapeutical perspectives","volume":"84","author":"Fhayli","year":"2019","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0085","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.lfs.2015.10.025","article-title":"Men and mice: relating their ages","volume":"152","author":"Dutta","year":"2016","journal-title":"Life Sci."},{"key":"10.1016\/j.actbio.2026.01.030_bib0086","doi-asserted-by":"crossref","unstructured":"E.C. Davis, Histochemistry stability of elastin in the developing mouse a quantitative radioautographic study, 1993.","DOI":"10.1007\/BF00268874"},{"key":"10.1016\/j.actbio.2026.01.030_bib0087","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1152\/physrev.00041.2008","article-title":"Vascular extracellular matrix and arterial mechanics","volume":"89","author":"Wagenseil","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.actbio.2026.01.030_bib0088","doi-asserted-by":"crossref","unstructured":"L.C.Y. Wong, B.L. Langille, Developmental remodeling of the internal elastic lamina of rabbit arteries effect of blood flow, 1996. http:\/\/ahajournals.org.","DOI":"10.1161\/01.RES.78.5.799"},{"key":"10.1016\/j.actbio.2026.01.030_bib0089","article-title":"Morphologic features of the normal aortic arch in neonates","author":"Machii","year":"1997","journal-title":"Infants, Child. Pertin. Growth"},{"key":"10.1016\/j.actbio.2026.01.030_bib0090","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/jocs.12367","article-title":"Aortic coarctation repair in the adult","volume":"29","author":"Cardoso","year":"2014","journal-title":"J. Card. Surg."},{"key":"10.1016\/j.actbio.2026.01.030_bib0091","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.817866","article-title":"Isolated coarctation of the aorta: current concepts and perspectives","volume":"9","author":"Bhatt","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.actbio.2026.01.030_bib0092","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/S0735-1097(02)02598-6","article-title":"Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment","volume":"40","author":"Chung","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.actbio.2026.01.030_bib0093","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1164\/ajrccm.159.3.9804027","article-title":"Chronic lung injury in preterm lambs","volume":"159","author":"Albertine","year":"1999","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.actbio.2026.01.030_bib0094","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/cyt.13174","article-title":"Parametric or nonparametric statistical tests: considerations when choosing the most appropriate option for your data","volume":"33","author":"Vrbin","year":"2022","journal-title":"Cytopathology"},{"key":"10.1016\/j.actbio.2026.01.030_bib0095","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1161\/CIRCULATIONAHA.118.036344","article-title":"Endothelial C-type natriuretic peptide is a critical regulator of angiogenesis and vascular remodeling","volume":"139","author":"Bubb","year":"2019","journal-title":"Circulation"}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126000383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126000383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T08:18:42Z","timestamp":1773994722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706126000383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":95,"alternative-id":["S1742706126000383"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2026.01.030","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural and mechanical analysis of treated and untreated aortic coarctation in a growing porcine model","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2026.01.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Acta Materialia Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}