{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:06:59Z","timestamp":1791270419015,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82572420"],"award-info":[{"award-number":["82572420"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302388"],"award-info":[{"award-number":["82302388"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024YQ068"],"award-info":[{"award-number":["ZR2024YQ068"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024QH150"],"award-info":[{"award-number":["ZR2024QH150"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["K2025LC3101"],"award-info":[{"award-number":["K2025LC3101"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["K2025LC7305"],"award-info":[{"award-number":["K2025LC7305"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFFO715101"],"award-info":[{"award-number":["2023YFFO715101"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.actbio.2026.05.011","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T09:29:35Z","timestamp":1778578175000},"page":"243-257","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Bioinspired aligned electroconductive hydrogel nanofiber patch enhances peripheral nerve repair through mechanosensitive calcium influx and focal adhesion kinase\/protein kinase B pathway activation"],"prefix":"10.1016","volume":"217","author":[{"given":"Bingcheng","family":"Yi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihui","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2474-4197","authenticated-orcid":false,"given":"Qihui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.actbio.2026.05.011_bib0001","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1002\/mus.28185","article-title":"Assessment, management, and rehabilitation of traumatic peripheral nerve injuries for non-surgeons","volume":"71","author":"Bateman","year":"2025","journal-title":"Muscle Nerve"},{"issue":"11","key":"10.1016\/j.actbio.2026.05.011_bib0002","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.tins.2024.09.009","article-title":"The injured axon: intrinsic mechanisms driving axonal regeneration","volume":"47","author":"Tom\u00e9","year":"2024","journal-title":"Trends Neurosci."},{"issue":"10","key":"10.1016\/j.actbio.2026.05.011_bib0003","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/s41593-020-0689-4","article-title":"A glycolytic shift in Schwann cells supports injured axons","volume":"23","author":"Babetto","year":"2020","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.actbio.2026.05.011_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102667","article-title":"Oxidative stress and mitochondrial impairment: key drivers in neurodegenerative disorders","volume":"104","author":"Wen","year":"2025","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.actbio.2026.05.011_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2024.102438","article-title":"The phenotypic changes of Schwann cells promote the functional repair of nerve injury","volume":"106","author":"Liao","year":"2024","journal-title":"Neuropeptides"},{"key":"10.1016\/j.actbio.2026.05.011_bib0006","article-title":"The combination of aligned PDA-Fe@ PLCL conduit with aligned GelMA hydrogel promotes peripheral nerve regeneration","volume":"14","author":"Wang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"3","key":"10.1016\/j.actbio.2026.05.011_bib0007","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202101663","article-title":"Biomimetic scaffolds for spinal cord applications exhibit stiffness-dependent immunomodulatory and neurotrophic characteristics","volume":"11","author":"Woods","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0008","first-page":"521","article-title":"Functional biomaterials for modulating the dysfunctional pathological microenvironment of spinal cord injury","volume":"39","author":"Ma","year":"2024","journal-title":"Bioact. Mater."},{"issue":"9","key":"10.1016\/j.actbio.2026.05.011_bib0009","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/s41578-020-0209-x","article-title":"Engineered biomaterials for in situ tissue regeneration","volume":"5","author":"Gaharwar","year":"2020","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmt.2024.100068","article-title":"Embracing the future: the application of regenerative biomaterials in the spinal disorders","volume":"9","author":"Xu","year":"2025","journal-title":"Biomed. Technol."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0011","first-page":"960","article-title":"Overview of injectable hydrogels for the treatment of myocardial infarction","volume":"9","author":"Yi","year":"2024","journal-title":"Cardiovasc. Innov. Appl."},{"issue":"28","key":"10.1016\/j.actbio.2026.05.011_bib0012","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202302519","article-title":"A bioinspired self-healing conductive hydrogel promoting peripheral nerve regeneration","volume":"10","author":"Xuan","year":"2023","journal-title":"Adv. Sci."},{"issue":"28","key":"10.1016\/j.actbio.2026.05.011_bib0013","article-title":"Ultrasound-responsive aligned piezoelectric nanofibers derived hydrogel conduits for peripheral nerve regeneration","volume":"36","author":"Xu","year":"2024","journal-title":"Adv. Mater.s"},{"issue":"41","key":"10.1016\/j.actbio.2026.05.011_bib0014","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202203829","article-title":"Natural polymer-derived bioscaffolds for peripheral nerve regeneration","volume":"32","author":"Zhang","year":"2022","journal-title":"Adv. Funct. Mater."},{"issue":"11","key":"10.1016\/j.actbio.2026.05.011_bib0015","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1038\/s41592-023-02020-9","article-title":"Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion","volume":"20","author":"Liu","year":"2023","journal-title":"Nat. Methods"},{"key":"10.1016\/j.actbio.2026.05.011_bib0016","first-page":"529","article-title":"Aligned fibrin\/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery","volume":"8","author":"Yang","year":"2022","journal-title":"Bioact. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0017","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41427-022-00368-6","article-title":"NSC-derived extracellular matrix-modified GelMA hydrogel fibrous scaffolds for spinal cord injury repair","volume":"14","author":"Chen","year":"2022","journal-title":"NPG Asia Mater."},{"issue":"2","key":"10.1016\/j.actbio.2026.05.011_bib0018","doi-asserted-by":"crossref","DOI":"10.1002\/jbm.a.37880","article-title":"Liquid metal-based conductive nerve guidance conduit combined with electrical stimulation boosts peripheral nerve repair","volume":"113","author":"Zhu","year":"2025","journal-title":"J. Biomed. Mater. Res. Part A"},{"key":"10.1016\/j.actbio.2026.05.011_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.nanoen.2022.108145","article-title":"Engineering a wirelessly self-powered and electroconductive scaffold to promote peripheral nerve regeneration","volume":"107","author":"Yang","year":"2023","journal-title":"Nano Energy"},{"key":"10.1016\/j.actbio.2026.05.011_bib0020","first-page":"287","article-title":"Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport","volume":"39","author":"Bai","year":"2024","journal-title":"Bioact. Mater."},{"issue":"7","key":"10.1016\/j.actbio.2026.05.011_bib0021","doi-asserted-by":"crossref","DOI":"10.1002\/smsc.202300008","article-title":"Recent progress on poly (3, 4-ethylenedioxythiophene): poly (styrenesulfonate) bioelectrodes","volume":"3","author":"Du","year":"2023","journal-title":"Small Sci."},{"key":"10.1016\/j.actbio.2026.05.011_bib0022","doi-asserted-by":"crossref","DOI":"10.1002\/admt.202401996","article-title":"Microfluidic spinning of PEDOT: PSS microfibers for nerve guidance conduits","volume":"10","author":"Geiger","year":"2025","journal-title":"Adv. Mater. Technol."},{"issue":"6","key":"10.1016\/j.actbio.2026.05.011_bib0023","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/s41423-019-0223-3","article-title":"The benefits of neuroinflammation for the repair of the injured central nervous system","volume":"16","author":"Yong","year":"2019","journal-title":"Cell. Mol. Immunol."},{"issue":"10","key":"10.1016\/j.actbio.2026.05.011_bib0024","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1039\/D3MA00736G","article-title":"Biomaterial strategies for regulating the neuroinflammatory response","volume":"5","author":"Galindo","year":"2024","journal-title":"Mater. Adv."},{"issue":"7","key":"10.1016\/j.actbio.2026.05.011_bib0025","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/s41578-022-00426-z","article-title":"Design of therapeutic biomaterials to control inflammation","volume":"7","author":"Tu","year":"2022","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0026","article-title":"Poly (Tannic Acid) based nanocomposite as a promising potential in biomedical applications","volume":"95","author":"Pourmadadi","year":"2024","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"6","key":"10.1016\/j.actbio.2026.05.011_bib0027","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1007\/s11064-022-03547-7","article-title":"Tannic acid attenuates peripheral and brain changes in a preclinical rat model of glioblastoma by modulating oxidative stress and purinergic signaling","volume":"47","author":"Bona","year":"2022","journal-title":"Neurochem. Res."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0028","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41427-025-00610-x","article-title":"Polydopamine-modified hydrogel nanofibers for sustained SFRP2 release: synergistic promotion of angiogenesis and nerve regeneration","volume":"17","author":"Zhang","year":"2025","journal-title":"NPG Asia Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0029","article-title":"Motion-driven piezoelectric response in self-powered hydrogel nanofibers enhances wound healing via intermediate filament remodeling and modulation of energy metabolism","volume":"18","author":"Xu","year":"2025","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.actbio.2026.05.011_bib0030","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jneumeth.2013.11.012","article-title":"The functional and morphological characteristics of sciatic nerve degeneration and regeneration after crush injury in rats","volume":"222","author":"Sta","year":"2014","journal-title":"J. Neurosci. Methods"},{"issue":"6","key":"10.1016\/j.actbio.2026.05.011_bib0031","doi-asserted-by":"crossref","first-page":"531","DOI":"10.55730\/1300-0144.5135","article-title":"Peripheral nerve regeneration at two and three weeks after crush injury of sciatic nerves in rat a light microscopic study","volume":"26","author":"Canpolat","year":"1996","journal-title":"Turk. J. Med. Sci."},{"key":"10.1016\/j.actbio.2026.05.011_bib0032","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202403722","article-title":"Adhesive and conductive fibrous hydrogel bandages for effective peripheral nerve regeneration","volume":"14","author":"Jin","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"4","key":"10.1016\/j.actbio.2026.05.011_bib0033","article-title":"Bioinspired hydrogel electrospun fibers for spinal cord regeneration","volume":"29","author":"Chen","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0034","doi-asserted-by":"crossref","first-page":"7993","DOI":"10.1038\/s41467-024-52418-y","article-title":"Highly-stable, injectable, conductive hydrogel for chronic neuromodulation","volume":"15","author":"Yang","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.actbio.2026.05.011_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.129536","article-title":"Acoustic transmitted electrospun fibrous membranes for tympanic membrane regeneration","volume":"419","author":"Wang","year":"2021","journal-title":"Chem. Eng. J."},{"issue":"5","key":"10.1016\/j.actbio.2026.05.011_bib0036","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1039\/C6QM00202A","article-title":"A novel radiation chemistry-based methodology for the synthesis of PEDOT\/Ag nanocomposites","volume":"1","author":"Cui","year":"2017","journal-title":"Mater. Chem. Front."},{"issue":"38","key":"10.1016\/j.actbio.2026.05.011_bib0037","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202402698","article-title":"Constructing nerve guidance conduit using dECM-doped conductive hydrogel to promote peripheral nerve regeneration","volume":"34","author":"Yan","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0038","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.apsusc.2018.04.168","article-title":"The effect of tannic acids on the electrical conductivity of PEDOT:PSS Films","volume":"448","author":"Yi","year":"2018","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.actbio.2026.05.011_bib0039","article-title":"Lysine-doped polydopamine coating enhances antithrombogenicity and endothelialization of an electrospun aligned fibrous vascular graft","volume":"25","author":"Yi","year":"2021","journal-title":"Appl. Mater. Today"},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0040","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41427-025-00610-x","article-title":"Polydopamine-modified hydrogel nanofibers for sustained SFRP2 release: synergistic promotion of angiogenesis and nerve regeneration","volume":"17","author":"Zhang","year":"2025","journal-title":"Npg Asia Mater."},{"issue":"4","key":"10.1016\/j.actbio.2026.05.011_bib0041","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202403370","article-title":"The combination of aligned PDA-Fe@PLCL conduit with aligned GelMA hydrogel promotes peripheral nerve regeneration","volume":"14","author":"Wang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"7","key":"10.1016\/j.actbio.2026.05.011_bib0042","doi-asserted-by":"crossref","first-page":"6867","DOI":"10.1021\/acsami.9b00293","article-title":"Stiffness of aligned fibers regulates the phenotypic expression of vascular smooth muscle cells","volume":"11","author":"Yi","year":"2019","journal-title":"ACS Appl. Mater. Interfaces."},{"key":"10.1016\/j.actbio.2026.05.011_bib0043","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.actbio.2020.03.022","article-title":"Stiffness of the aligned fibers affects structural and functional integrity of the oriented endothelial cells","volume":"108","author":"Yi","year":"2020","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0044","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.apsb.2024.10.004","article-title":"Oxidative stress and inflammation in the pathogenesis of neurological disorders: mechanisms and implications","volume":"15","author":"Dash","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.actbio.2026.05.011_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.134146","article-title":"Advances in tannic acid-incorporated biomaterials: infection treatment, regenerative medicine, cancer therapy, and biosensing","volume":"432","author":"Bigham","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.actbio.2026.05.011_bib0046","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1007\/s13197-018-3292-x","article-title":"Antioxidant and \u03b1-amylase inhibitory activities of tannic acid","volume":"55","author":"Lou","year":"2018","journal-title":"J. Food Sci. Technol."},{"key":"10.1016\/j.actbio.2026.05.011_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.126552","article-title":"Poly (3, 4-ethylenedioxythiophene)(PEDOT) as promising thermoelectric materials and devices","volume":"404","author":"Xu","year":"2021","journal-title":"Chem. Eng. J."},{"issue":"11","key":"10.1016\/j.actbio.2026.05.011_bib0048","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2012.171","article-title":"JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry","volume":"3","author":"Perelman","year":"2012","journal-title":"Cell Death. Dis."},{"issue":"22","key":"10.1016\/j.actbio.2026.05.011_bib0049","doi-asserted-by":"crossref","first-page":"10956","DOI":"10.1039\/D4FO03549F","article-title":"Regulation of redox enzymes by nutraceuticals: a review of the roles of antioxidant polyphenols and peptides","volume":"15","author":"Obeme-Nmom","year":"2024","journal-title":"Food Funct."},{"issue":"3","key":"10.1016\/j.actbio.2026.05.011_bib0050","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s11010-023-04757-5","article-title":"Superoxide dismutase: a key target for the neuroprotective effects of curcumin","volume":"479","author":"Khayatan","year":"2024","journal-title":"Mol. Cell. Biochem."},{"issue":"6","key":"10.1016\/j.actbio.2026.05.011_bib0051","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1021\/acsapm.3c00445","article-title":"Mussel-inspired PEDOT-incorporated gelatin-based conductive hydrogel with flexibility and electroactivity to accelerate wound healing in vitro","volume":"5","author":"Li","year":"2023","journal-title":"ACS Appl. Polym. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0052","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2121-14-32","article-title":"Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis","volume":"14","author":"Brentnall","year":"2013","journal-title":"BMC Cell Biol."},{"key":"10.1016\/j.actbio.2026.05.011_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2019.112963","article-title":"Electrical stimulation affects neural stem cell fate and function in vitro","volume":"319","author":"Zhu","year":"2019","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.actbio.2026.05.011_bib0054","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1016\/j.mod.2017.04.569","article-title":"Integrins act as mechanosensors to regulate cell survival and tissue homeostasis during morphogenesis","volume":"145","author":"Martin Bermudo","year":"2017","journal-title":"Mech. Dev."},{"key":"10.1016\/j.actbio.2026.05.011_bib0055","first-page":"82","article-title":"An overview of substrate stiffness guided cellular response and its applications in tissue regeneration","volume":"15","author":"Yi","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.actbio.2026.05.011_bib0056","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.biomaterials.2018.04.023","article-title":"Hydrogen bonds autonomously powered gelatin methacrylate hydrogels with super-elasticity, self-heal and underwater self-adhesion for sutureless skin and stomach surgery and E-skin","volume":"171","author":"Liu","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2026.05.011_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.160899","article-title":"Spiral-structured electrospun conductive conduits filled with aligned nanofibers for peripheral nerve regeneration","volume":"508","author":"Song","year":"2025","journal-title":"Chem. Eng. J."},{"issue":"2","key":"10.1016\/j.actbio.2026.05.011_bib0058","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/s41580-024-00777-1","article-title":"The role and regulation of integrins in cell migration and invasion","volume":"26","author":"Chastney","year":"2025","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.actbio.2026.05.011_bib0059","first-page":"657","article-title":"Step-wise CAG@ PLys@ PDA-Cu2+ modification on micropatterned nanofibers for programmed endothelial healing","volume":"25","author":"Yi","year":"2023","journal-title":"Bioact. Mater."},{"issue":"7","key":"10.1016\/j.actbio.2026.05.011_bib0060","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1038\/s41563-025-02214-w","article-title":"Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury","volume":"24","author":"Wang","year":"2025","journal-title":"Nat. Mater."},{"issue":"11","key":"10.1016\/j.actbio.2026.05.011_bib0061","doi-asserted-by":"crossref","first-page":"392","DOI":"10.31083\/j.fbl2911392","article-title":"Signal transduction mechanisms of focal adhesions: src and FAK-mediated cell response","volume":"29","author":"Katoh","year":"2024","journal-title":"Fronti. Biosci."},{"issue":"47","key":"10.1016\/j.actbio.2026.05.011_bib0062","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202405705","article-title":"Piezo1 Regulates stiffness-dependent DRG axon regeneration via modifying cytoskeletal dynamics","volume":"11","author":"Lei","year":"2024","journal-title":"Adv. Sci."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0063","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/s13578-023-01128-x","article-title":"PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis","volume":"13","author":"Wang","year":"2023","journal-title":"Cell Biosci."},{"issue":"22","key":"10.1016\/j.actbio.2026.05.011_bib0064","article-title":"Ion electron-coupled functionality in materials and devices based on conjugated polymers","volume":"31","author":"Berggren","year":"2019","journal-title":"Adv. Mater."},{"issue":"2","key":"10.1016\/j.actbio.2026.05.011_bib0065","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1039\/D5TC03054D","article-title":"PEDOT:PSS conducting eutectogel for enhanced electrical recording and stimulation in implantable neural interfaces","volume":"14","author":"Kasavetov","year":"2026","journal-title":"J. Mater. Chem. C"},{"issue":"11","key":"10.1016\/j.actbio.2026.05.011_bib0066","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/s41580-024-00773-5","article-title":"Mechanisms of mechanotransduction and physiological roles of PIEZO channels","volume":"25","author":"Xiao","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0067","doi-asserted-by":"crossref","DOI":"10.1111\/nan.70000","article-title":"A homozygous ATP2A2 variant alters sarcoendoplasmic reticulum Ca2+-ATPase 2 function in skeletal muscle and causes a novel vacuolar myopathy","volume":"51","author":"Llans\u00f3","year":"2025","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.actbio.2026.05.011_bib0068","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13578-020-00522-z","article-title":"Structure, kinetic properties and biological function of mechanosensitive Piezo channels","volume":"11","author":"Fang","year":"2021","journal-title":"Cell Biosci."},{"key":"10.1016\/j.actbio.2026.05.011_bib0069","article-title":"The mechanisms of interaction between biomaterials and cells\/cellular microenvironment and the applications in neural injuries","author":"Chi","year":"2024","journal-title":"Chinese Chem.l Lett."},{"issue":"2","key":"10.1016\/j.actbio.2026.05.011_bib0070","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1089\/ten.teb.2024.0100","article-title":"The role of macrophages in nerve regeneration: polarization and combination with tissue engineering","volume":"31","author":"Li","year":"2025","journal-title":"Tissue Eng. Part B"},{"key":"10.1016\/j.actbio.2026.05.011_bib0071","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123103","article-title":"Conductive hydrogel luminal filler for peripheral nerve regeneration","volume":"317","author":"Park","year":"2025","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.actbio.2026.05.011_bib0072","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/s41577-022-00792-3","article-title":"Death by TNF: a road to inflammation","volume":"23","author":"van Loo","year":"2023","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0073","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nn.3599","article-title":"Identification of a unique TGF-\u03b2-dependent molecular and functional signature in microglia","volume":"17","author":"Butovsky","year":"2014","journal-title":"Nat. Neurosci."},{"issue":"6","key":"10.1016\/j.actbio.2026.05.011_bib0074","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nrneph.2016.48","article-title":"TGF-\u03b2: the master regulator of fibrosis","volume":"12","author":"Meng","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"issue":"1","key":"10.1016\/j.actbio.2026.05.011_bib0075","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3390\/biom12010025","article-title":"Stimulation of neurite outgrowth using autologous NGF bound at the surface of a fibrous substrate","volume":"12","author":"Casanova","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.actbio.2026.05.011_bib0076","doi-asserted-by":"crossref","DOI":"10.1016\/j.bas.2026.105951","article-title":"Advances in peripheral nerve reconstruction: current clinical conduits, comparative outcomes, limitations, and future technological perspectives","author":"Rochkind","year":"2026","journal-title":"Brain Spine"}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126002953?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126002953?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T14:44:29Z","timestamp":1783176269000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706126002953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":76,"alternative-id":["S1742706126002953"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2026.05.011","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioinspired aligned electroconductive hydrogel nanofiber patch enhances peripheral nerve repair through mechanosensitive calcium influx and focal adhesion kinase\/protein kinase B pathway activation","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2026.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Acta Materialia Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}