{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:53:49Z","timestamp":1791021229612,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004024","name":"Jinan University","doi-asserted-by":"publisher","award":["SKLBMDA-2025104"],"award-info":[{"award-number":["SKLBMDA-2025104"]}],"id":[{"id":"10.13039\/501100004024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373811"],"award-info":[{"award-number":["82373811"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2025A1515010587"],"award-info":[{"award-number":["2025A1515010587"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.actbio.2026.08.046","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:36:45Z","timestamp":1787787405000},"page":"153-167","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A strong wet-adhesive hydrogel with reactive oxygen species-scavenging and sustained estradiol release for intrauterine adhesion prevention"],"prefix":"10.1016","volume":"223","author":[{"given":"Wanzhen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zijun","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengsheng","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danni","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conghan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0574-7483","authenticated-orcid":false,"given":"Chunshun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2026.08.046_bib0001","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2147\/IJWH.S165474","article-title":"Asherman\u2019s syndrome: current perspectives on diagnosis and management","volume":"11","author":"Dreisler","year":"2019","journal-title":"Int. J. Womens Health"},{"issue":"7","key":"10.1016\/j.actbio.2026.08.046_bib0002","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1007\/s43032-020-00343-y","article-title":"Recent Advances in Understandings Towards Pathogenesis and Treatment for Intrauterine Adhesion and Disruptive Insights from Single-Cell Analysis","volume":"28","author":"Leung","year":"2021","journal-title":"Reprod. Sci."},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0003","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s11427-019-1572-7","article-title":"Recent advances in mammalian reproductive biology","volume":"63","author":"Wen","year":"2020","journal-title":"Sci. China Life Sci."},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0004","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s13287-025-04298-2","article-title":"Human embryonic stem cell-derived immunity-and-matrix-regulatory cells promote endometrial repair and fertility restoration in IUA rats","volume":"16","author":"Cao","year":"2025","journal-title":"Stem Cell Res Ther"},{"issue":"3","key":"10.1016\/j.actbio.2026.08.046_bib0005","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.contraception.2004.09.005","article-title":"Twenty micrograms vs. >20 \u03bcg estrogen oral contraceptives for contraception: systematic review of randomized controlled trials","volume":"71","author":"Gallo","year":"2005","journal-title":"Contraception"},{"key":"10.1016\/j.actbio.2026.08.046_bib0006","doi-asserted-by":"crossref","unstructured":"J. Bosteels, S. Weyers, T. M. D\u2019Hooghe, H. Torrance, F. J. Broekmans, S. J. Chua, B. W. J. Mol, Anti-adhesion therapy following operative hysteroscopy for treatment of female subfertility - Bosteels, J - 2017 | Cochrane Library, (n.d.).","DOI":"10.1002\/14651858.CD011110.pub3"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0007","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s12978-017-0334-1","article-title":"Trends in use of and complications from intrauterine contraceptive devices and tubal ligation or occlusion","volume":"14","author":"Howard","year":"2017","journal-title":"Reprod Health"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0008","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20220006","article-title":"Developing biomedical engineering technologies for reproductive medicine","volume":"1","author":"Zhu","year":"2022","journal-title":"Smart Medicine"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0009","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/s12951-025-03989-5","article-title":"Hydrogels strategies for organ adhesions: from mechanism to application","volume":"24","author":"Liang","year":"2026","journal-title":"J Nanobiotechnol"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2023.12.039","article-title":"Effects and safety of hyaluronic acid gel on intrauterine adhesion and fertility after intrauterine surgery: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials","volume":"231","author":"Luo","year":"2024","journal-title":"American Journal of Obstetrics & Gynecology"},{"issue":"2","key":"10.1016\/j.actbio.2026.08.046_bib0011","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jmig.2020.06.030","article-title":"Auto\u2013Cross-Linked Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions after Hysteroscopic Adhesiolysis: A Randomized Controlled Trial","volume":"28","author":"Zhou","year":"2021","journal-title":"Journal of Minimally Invasive Gynecology"},{"issue":"7","key":"10.1016\/j.actbio.2026.08.046_bib0012","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.fertnstert.2018.07.021","article-title":"Reproductive performance after the application of hyaluronic acid gel after dilation and curettage in women who have experienced at least one previous curettage: long-term results of a multicenter prospective randomized trial","volume":"110","author":"Hooker","year":"2018","journal-title":"Fertility and Sterility"},{"issue":"35","key":"10.1016\/j.actbio.2026.08.046_bib0013","doi-asserted-by":"crossref","first-page":"29580","DOI":"10.1021\/acsami.7b10211","article-title":"Dual Regulations of Thermosensitive Heparin\u2013Poloxamer Hydrogel Using \u03b5-Polylysine: Bioadhesivity and Controlled KGF Release for Enhancing Wound Healing of Endometrial Injury","volume":"9","author":"Xu","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"6","key":"10.1016\/j.actbio.2026.08.046_bib0014","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1109\/TUFFC.2022.3165688","article-title":"Characterization of Uterine Peristaltic Waves by Ultrasound Strain Analysis","volume":"69","author":"Huang","year":"2022","journal-title":"IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control"},{"key":"10.1016\/j.actbio.2026.08.046_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122615","article-title":"Locationally activated PRP via an injectable dual-network hydrogel for endometrial regeneration","volume":"309","author":"Qi","year":"2024","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.actbio.2026.08.046_bib0016","doi-asserted-by":"crossref","first-page":"931","DOI":"10.3390\/jcm11040931","article-title":"Chemically Modified Hyaluronic Acid for Prevention of Post-Surgical Adhesions: New Aspects of Gel Barriers Physical Profiles","volume":"11","author":"Torres-de La Roche","year":"2022","journal-title":"JCM"},{"key":"10.1016\/j.actbio.2026.08.046_bib0017","article-title":"Application of Bioactive Hydrogels for Functional Treatment of Intrauterine Adhesion","volume":"9","author":"Wang","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"12","key":"10.1016\/j.actbio.2026.08.046_bib0018","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146159","article-title":"The Overexpression of TGF-\u03b2 and CCN2 in Intrauterine Adhesions Involves the NF-\u03baB Signaling Pathway","volume":"10","author":"Xue","year":"2015","journal-title":"PLoS ONE"},{"issue":"7","key":"10.1016\/j.actbio.2026.08.046_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107201","article-title":"Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH","volume":"26","author":"Yao","year":"2023","journal-title":"iScience"},{"issue":"4","key":"10.1016\/j.actbio.2026.08.046_bib0020","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.ajpath.2012.02.004","article-title":"Recent Developments in Myofibroblast Biology","volume":"180","author":"Hinz","year":"2012","journal-title":"The American Journal of Pathology"},{"key":"10.1016\/j.actbio.2026.08.046_bib0021","doi-asserted-by":"crossref","first-page":"9667","DOI":"10.2147\/IJN.S527637","article-title":"Unveiling the Pathological Landscape of Intrauterine Adhesion: Mechanistic Insights and Exosome-Biomaterial Therapeutic Innovations","volume":"20","author":"Qin","year":"2025","journal-title":"IJN Volume"},{"issue":"12","key":"10.1016\/j.actbio.2026.08.046_bib0023","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.3390\/ijms21124349","article-title":"Estrogen Receptors and Estrogen-Induced Uterine Vasodilation in Pregnancy","volume":"21","author":"Bai","year":"2020","journal-title":"International Journal of Molecular Sciences"},{"issue":"6","key":"10.1016\/j.actbio.2026.08.046_bib0024","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1007\/s43032-022-01108-5","article-title":"Repairing and Regenerating Injured Endometrium Methods","volume":"30","author":"Liu","year":"2023","journal-title":"Reprod. Sci."},{"issue":"3","key":"10.1016\/j.actbio.2026.08.046_bib0025","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.3390\/jcm14031021","article-title":"Cine-MRI for Quantifying Uterine Peristalsis: A Systematic Review and Meta-Analysis","volume":"14","author":"Vidal","year":"2025","journal-title":"JCM"},{"key":"10.1016\/j.actbio.2026.08.046_bib0026","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.actbio.2025.01.033","article-title":"Equilibrium mechanical properties of the human uterus in tension and compression","volume":"194","author":"Fang","year":"2025","journal-title":"Acta Biomaterialia"},{"key":"10.1016\/j.actbio.2026.08.046_bib0027","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.addr.2019.03.006","article-title":"Drug therapies and delivery mechanisms to treat perturbed skin wound healing","volume":"149\u2013150","author":"Chin","year":"2019","journal-title":"Advanced Drug Delivery Reviews"},{"key":"10.1016\/j.actbio.2026.08.046_bib0028","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.freeradbiomed.2013.01.034","article-title":"17\u03b2-Estradiol and steady-state concentrations of H2O2: antiapoptotic effect in endometrial cells from patients with endometriosis","volume":"60","author":"Andrade","year":"2013","journal-title":"Free Radical Biology and Medicine"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0029","doi-asserted-by":"crossref","first-page":"8765","DOI":"10.1038\/s41598-022-12803-3","article-title":"Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent","volume":"12","author":"Shojaee","year":"2022","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.actbio.2026.08.046_bib0030","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1152\/physrev.00031.2019","article-title":"Physiology of the Endometrium and Regulation of Menstruation","volume":"100","author":"Critchley","year":"2020","journal-title":"Physiological Reviews"},{"issue":"6","key":"10.1016\/j.actbio.2026.08.046_bib0031","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1093\/humupd\/dmv038","article-title":"Menstrual physiology: implications for endometrial pathology and beyond","volume":"21","author":"Maybin","year":"2015","journal-title":"Hum. Reprod. Update"},{"issue":"1","key":"10.1016\/j.actbio.2026.08.046_bib0032","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev-cellbio-011723-021442","article-title":"Mechanisms of Regeneration and Fibrosis in the Endometrium","volume":"39","author":"Ang","year":"2023","journal-title":"Annu. Rev. Cell Dev. Biol."},{"issue":"7","key":"10.1016\/j.actbio.2026.08.046_bib0033","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nm.2807","article-title":"Mechanisms of fibrosis: therapeutic translation for fibrotic disease","volume":"18","author":"Wynn","year":"2012","journal-title":"Nat Med"},{"issue":"10","key":"10.1016\/j.actbio.2026.08.046_bib0034","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/s41591-020-1040-z","article-title":"Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle","volume":"26","author":"Wang","year":"2020","journal-title":"Nat Med"}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126005799?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706126005799?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:03:16Z","timestamp":1791018196000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706126005799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":33,"alternative-id":["S1742706126005799"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2026.08.046","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A strong wet-adhesive hydrogel with reactive oxygen species-scavenging and sustained estradiol release for intrauterine adhesion prevention","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2026.08.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Acta Materialia Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}