{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:41:43Z","timestamp":1770885703840,"version":"3.50.1"},"reference-count":64,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Histochemica"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.acthis.2017.06.003","type":"journal-article","created":{"date-parts":[[2017,6,12]],"date-time":"2017-06-12T22:01:31Z","timestamp":1497304891000},"page":"592-601","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Neuroprotective potential of Aloe arborescens against copper induced neurobehavioral features of Parkinson\u2019s disease in rat"],"prefix":"10.1016","volume":"119","author":[{"given":"Abdellatif","family":"Abbaoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar El","family":"Hiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halima","family":"Gamrani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.acthis.2017.06.003_bib0005","first-page":"10","article-title":"The neuronal basis of copper induced modulation of anxiety state in rat","volume":"119","author":"Abbaoui","year":"2016","journal-title":"Acta Histochem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0010","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0165-0173(97)00045-3","article-title":"Neurodegenerative disorders in humans: the role ofglutathione in oxidative stress-mediated neuronal death","volume":"25","author":"Bains","year":"1997","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.acthis.2017.06.003_bib0015","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1081\/CLT-100102421","article-title":"Copper","volume":"37","author":"Barceloux","year":"1999","journal-title":"J. Toxicol. Clin. Toxicol."},{"issue":"2","key":"10.1016\/j.acthis.2017.06.003_bib0020","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/eesa.1995.1098","article-title":"Elevated copper levels during larval development cause altered locomotor behavior in the adult carabid beetle Pterostichus cupreus L. (Coleoptera: Carbidae)","volume":"32","author":"Bayley","year":"1995","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.acthis.2017.06.003_bib0025","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.acthis.2014.03.002","article-title":"A blunted anxiolytic likeeffect of curcumin against acute lead induced anxiety in rat: involvement ofserotonin","volume":"116","author":"Benammi","year":"2014","journal-title":"Acta Histochem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0030","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0378-8741(03)00268-X","article-title":"Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats","volume":"89","author":"Beppu","year":"2003","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0035","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jep.2005.10.034","article-title":"Antidiabetic effects of dietary administration of Aloe arborescens Miller component on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components","volume":"103","author":"Beppu","year":"2006","journal-title":"J. Ethnopharmacol."},{"issue":"2\u20133","key":"10.1016\/j.acthis.2017.06.003_bib0040","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ejphar.2008.03.008","article-title":"Health effects of quercetin: from antioxidant to nutraceutical","volume":"585","author":"Boots","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0045","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1006\/abbi.2001.2509","article-title":"A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols and cer- uloplasmin","volume":"394","author":"Burkitt","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.acthis.2017.06.003_bib0050","doi-asserted-by":"crossref","first-page":"S1754","DOI":"10.1016\/S2221-1691(12)60490-0","article-title":"Protective effects of the aqueous leaf extract of Aloe barbadensis on gentamicin and cisplatin-induced nephrotoxic rats","volume":"2","author":"Chatterjee","year":"2012","journal-title":"Asia. Pac. J. Trop. Biomed."},{"key":"10.1016\/j.acthis.2017.06.003_bib0055","first-page":"283","article-title":"Inhibition of N-ethyl-N\u2032-nitro-N-nitrosoguanidine-induced duodenal tumorigenesis in mice by whole-leaf Aloe arborescens","volume":"1","author":"Chihara","year":"2000","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"11","key":"10.1016\/j.acthis.2017.06.003_bib0060","first-page":"1993","article-title":"Aloe arborescens extract protects IMR-32Cells against Alzheimer amyloid beta peptide via inhibition of radical peroxide production","volume":"10","author":"Clementi","year":"2015","journal-title":"Nat. Prod. Commun."},{"key":"10.1016\/j.acthis.2017.06.003_bib0065","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1750-3639.1999.tb00217.x","article-title":"Oxidative stress and motor neurone disease","volume":"9","author":"Cookson","year":"1999","journal-title":"Brain Pathol."},{"issue":"9","key":"10.1016\/j.acthis.2017.06.003_bib0070","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/ncpneuro0291","article-title":"Wilson\u2019s disease: an update","volume":"2","author":"Das","year":"2006","journal-title":"Nat. Clin. Pract. Neurol."},{"issue":"3","key":"10.1016\/j.acthis.2017.06.003_bib0075","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0166-445X(95)00022-V","article-title":"Brain monoamine levels and energy status in common carp (Cyprinus carpio) after exposure to sublethal levels of copper","volume":"33","author":"De Boecka","year":"1995","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0080","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.acthis.2013.01.006","article-title":"Loss of tyrosine hydroxylase expression within the nigro-striato-cortical pathways in the cirrhotic rat: the possible restorative effect of the neurosteroid dehydroepiandrosterone sulfate","volume":"115","author":"El Hiba","year":"2013","journal-title":"Acta Histochem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0085","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.crvi.2012.05.006","article-title":"Alteration of dopaminergic innervation and voluntary movements after long period of thirst in a semi-desert rodent, Meriones shawi: behavioral and immunohistochemical studies","volume":"335","author":"Elgot","year":"2012","journal-title":"C. R. Biol."},{"issue":"6","key":"10.1016\/j.acthis.2017.06.003_bib0090","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/mnfr.200500014","article-title":"Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29","volume":"49","author":"Ferguson","year":"2005","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0095","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0300-483X(03)00159-8","article-title":"Copper toxicity, oxidative stress, and antioxidant nutrients","volume":"189","author":"Gaetke","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.acthis.2017.06.003_bib0100","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0308-8146(02)00145-0","article-title":"Antioxidant and pro-oxidant properties of ascorbic acid and gallic acid","volume":"79","author":"Gow-Chin","year":"2002","journal-title":"Food Chem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0105","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1055\/s-0031-1298453","article-title":"Anticancer potential of aloes: antioxidant, antiproliferative, and immunostimulatory attributes","volume":"78","author":"Harlev","year":"2012","journal-title":"Planta Med."},{"issue":"4","key":"10.1016\/j.acthis.2017.06.003_bib0110","first-page":"183","article-title":"Isolation and hypoglycemic activity of arborans A and B, glycans of Aloe arborescens var. Natalensis Leaves","volume":"24","author":"Hikino","year":"1986","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0115","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.foodchem.2005.09.084","article-title":"Investigation of the antioxidant properties of Ferula orientalis L.using a suitable extraction procedure","volume":"100","author":"Kartal","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0120","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.saa.2013.06.110","article-title":"Spectroscopic studies on the antioxidant activity of p-coumaric acid","volume":"115","author":"Kilic","year":"2013","journal-title":"Spectrochim. Acta. A. Mol. Biomol. Spectrosc."},{"issue":"3","key":"10.1016\/j.acthis.2017.06.003_bib0125","first-page":"181","article-title":"Biopharmacutical assessment of eye drops containing Aloe vera","volume":"59","author":"Kodym","year":"2002","journal-title":"Acta Pol. Pharm. Drug Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0130","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.cellbi.2006.11.023","article-title":"Apoptosis affects integration frequency: adult stem cells injected in blastocysts show high caspase-3 activity","volume":"31","author":"Koestenbauer","year":"2007","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.acthis.2017.06.003_bib0135","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.cbi.2004.12.004","article-title":"Possible mechanisms underlying copper-induced damage in biological membranes leading to cellular toxicity","volume":"151","author":"Letelier","year":"2005","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.acthis.2017.06.003_bib0140","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.foodchem.2014.08.034","article-title":"Phytochemical constituents and in vitro radical scavenging activity of different aloe species","volume":"170","author":"Lucini","year":"2015","journal-title":"Food Chem."},{"issue":"20","key":"10.1016\/j.acthis.2017.06.003_bib0145","first-page":"4242","article-title":"Aloe arborescens aqueous gel extract alters the activities of key hepatic enzymes and blood concentration of triglyceride, glucose and insulin in alloxan-induced diabetic rats","volume":"10","author":"Mogale","year":"2011","journal-title":"Afr. J. Biotechnol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0150","doi-asserted-by":"crossref","first-page":"364","DOI":"10.5344\/ajev.1991.42.4.364","article-title":"Use of a modified dimethylaminocinnamaldehyde reagent for analysis of flavanols","volume":"42","author":"Nigel","year":"1991","journal-title":"Am. J. Enol. Vitic."},{"issue":"1","key":"10.1016\/j.acthis.2017.06.003_bib0155","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.aquatox.2004.04.006","article-title":"Copper-induced changes in locomotor behaviors and neuronal physiology of the freshwater oligochaete, Lumbriculus variegatus","volume":"69","author":"O\u2019Gara","year":"2004","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0160","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/ptr.2650070711","article-title":"Mechanism of antiinflammatory and antithermal burn action of CPase from Aloe arborescens Miller var natalensis Berger in rats and mice","volume":"7","author":"Obata","year":"1993","journal-title":"Phytother. Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0165","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5264\/eiyogakuzashi.44.307","article-title":"Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine","volume":"44","author":"Oyaizu","year":"1986","journal-title":"Jpn. J. Nutr."},{"key":"10.1016\/j.acthis.2017.06.003_bib0170","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1046\/j.1471-4159.2001.00243.x","article-title":"Copper neurotoxicity is dependent on dopamine-mediated copper uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line","volume":"77","author":"Paris","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0175","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2006"},{"key":"10.1016\/j.acthis.2017.06.003_bib0180","first-page":"1975","article-title":"Antimicrobial activity of different Aloe barbadensis Mill: and Aloe arborescens Mill. leaf fractions","volume":"6","author":"Pellizzoni","year":"2012","journal-title":"J. Med. Plant Res."},{"issue":"7","key":"10.1016\/j.acthis.2017.06.003_bib0185","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1093\/jn\/129.7.1251","article-title":"A delicate balance: homeostatic control of copper uptake and distribution","volume":"129","author":"Pena","year":"1999","journal-title":"J. Nutr."},{"issue":"6","key":"10.1016\/j.acthis.2017.06.003_bib0190","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s10534-011-9463-0","article-title":"Acute and chronic metal exposure impairs locomotion activity in Drosophila melanogaster: a model to study Parkinsonism","volume":"24","author":"Ramirez","year":"2011","journal-title":"BioMetals"},{"key":"10.1016\/j.acthis.2017.06.003_bib0195","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/15216540051081074","article-title":"Copper dependent oxidative stress and neurodegeneration","volume":"50","author":"Rotilio","year":"2000","journal-title":"IUBMB Life"},{"issue":"12","key":"10.1016\/j.acthis.2017.06.003_bib0200","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1002\/mds.21136","article-title":"Timmermann, L., Schnitzler, A. Wilson\u2019s disease tremor is associated with magnetic resonance imaging lesions in basal ganglia structures","volume":"21","author":"S\u00fcdmeyer","year":"2006","journal-title":"Mov. Disord."},{"key":"10.1016\/j.acthis.2017.06.003_bib0205","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/ptr.2650070707","article-title":"Purification of active substances of Aloe arborescens Miller and their biological and pharmacological activity","volume":"7","author":"Saito","year":"1993","journal-title":"Phytother. Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0210","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.acthis.2011.02.003","article-title":"Effects of chronicleadintoxication on rat serotoninergic system and anxiety behavior","volume":"114","author":"Sansar","year":"2012","journal-title":"Acta Histochem."},{"key":"10.1016\/j.acthis.2017.06.003_bib0215","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1046\/j.1471-4159.2000.0740270.x","article-title":"In situ oxidative catalysis by neurofibrillary tangles and senile in Alzheimer\u2019s disease: a central role for bound transition metals","volume":"74","author":"Sayre","year":"2000","journal-title":"J. Neurochem."},{"issue":"5\u20136","key":"10.1016\/j.acthis.2017.06.003_bib0220","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0166-445X(82)90020-0","article-title":"Locomotor behavior of four marine teleosts in response to sublethal copper exposure","volume":"2","author":"Scarfe","year":"1982","journal-title":"Aquat. Toxicol."},{"issue":"2","key":"10.1016\/j.acthis.2017.06.003_bib0225","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/ana.10276","article-title":"Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo","volume":"52","author":"Sheline","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0230","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1002\/ptr.826","article-title":"Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger","volume":"15","author":"Shimpo","year":"2001","journal-title":"Phytother Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0235","first-page":"585","article-title":"Effects of Aloe arborescens ingestion on azoxymethane-induced intestinal carcinogenesis and hematological and biochemical parameters of male F344 rats","volume":"7","author":"Shimpo","year":"2006","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"10.1016\/j.acthis.2017.06.003_bib0240","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5344\/ajev.1965.16.3.144","article-title":"Colorimetry of total phenolics with phosphomolibdic-phosphotungstic acid reagents","volume":"16","author":"Singleton","year":"1965","journal-title":"Am. J. Enol. Vitic."},{"key":"10.1016\/j.acthis.2017.06.003_bib0245","doi-asserted-by":"crossref","first-page":"480","DOI":"10.5114\/ceji.2013.39765","article-title":"Aloe arborescens and American cranberry (Vaccinium macrocarpon) extracts inhibit tumor-induced cutaneous angiogenesis in mice","volume":"38","author":"Skopi\u2019nski","year":"2013","journal-title":"Cent. Eur. J. Immunol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0250","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0361-9230(01)00454-3","article-title":"Copper in disorders with neurological symptoms: Alzheimer\u2019s, Menkes and Wilson diseases","volume":"55","author":"Strausak","year":"2001","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.acthis.2017.06.003_bib0255","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0014-5793(98)00630-9","article-title":"Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis","volume":"429","author":"Stridh","year":"1998","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.acthis.2017.06.003_bib0260","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00128-012-0636-5","article-title":"The acute and behavioral effects of a copper-nickel mixture on roach Rutilus rutilus","volume":"89","author":"Svecevi\u010dius","year":"2012","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0265","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/ptr.2650070714","article-title":"Inhibitory effect of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe) on induction of preneoplastic focal lesions in the rat liver","volume":"7","author":"Tsuda","year":"1993","journal-title":"Phytother. Res."},{"key":"10.1016\/j.acthis.2017.06.003_bib0270","series-title":"Modern Nutrition in Health and Disease","first-page":"241","article-title":"Copper","author":"Turnlund","year":"1999"},{"key":"10.1016\/j.acthis.2017.06.003_bib0275","doi-asserted-by":"crossref","first-page":"952S","DOI":"10.1093\/ajcn\/67.5.952S","article-title":"Essentiality of copper in humans","volume":"67","author":"Uauy","year":"1998","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.acthis.2017.06.003_bib0280","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0165-0270(99)00016-3","article-title":"A method to quantify glial fibrillary acidic protein immunoreactivity on the suprachiasmatic nucleus","volume":"88","author":"Vilaplana","year":"1999","journal-title":"J. Neurosci. Meth."},{"issue":"6","key":"10.1016\/j.acthis.2017.06.003_bib0285","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.neuro.2009.09.005","article-title":"Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles","volume":"30","author":"Wang","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.acthis.2017.06.003_bib0290","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1021\/es305133k","article-title":"Organic extract contaminants from drinking water activate Nrf2-mediatedantioxidant response in a human cell line","volume":"47","author":"Wang","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0295","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/B978-0-12-364931-7.50007-0","article-title":"Host defenses against copper toxicity","volume":"31","author":"Winge","year":"1990","journal-title":"Int. Rev. Exp. Pathol."},{"key":"10.1016\/j.acthis.2017.06.003_bib0300","doi-asserted-by":"crossref","first-page":"S159","DOI":"10.1111\/j.1750-3841.2006.00260.x","article-title":"A comparative study on phenolic profiles and antioxidant activities of legumes as affected by extraction solvents","volume":"72","author":"Xu","year":"2007","journal-title":"J. Food Sci."},{"key":"10.1016\/j.acthis.2017.06.003_bib0305","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1055\/s-2007-969126","article-title":"Structure determination of polysaccharides in Aloe arborescens var natalensis","volume":"50","author":"Yagi","year":"1986","journal-title":"Planta Med."},{"issue":"6","key":"10.1016\/j.acthis.2017.06.003_bib0310","first-page":"1627","article-title":"Anti-inflammatory active constituents of Aloe arborescens Miller","volume":"55","author":"Yamamoto","year":"1991","journal-title":"Agric. Biol. Chem."},{"issue":"2","key":"10.1016\/j.acthis.2017.06.003_bib0315","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s12264-008-0073-y","article-title":"Copper (Cu2+) induces degeneration of dopamnergic neurons in the nigrostriatal system of rats","volume":"24","author":"Yu","year":"2008","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.acthis.2017.06.003_bib0320","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0308-8146(98)00102-2","article-title":"The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals","volume":"64","author":"Zhishen","year":"1999","journal-title":"Food Chem."}],"container-title":["Acta Histochemica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065128117301113?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065128117301113?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:43:25Z","timestamp":1692837805000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0065128117301113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":64,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0065128117301113"],"URL":"https:\/\/doi.org\/10.1016\/j.acthis.2017.06.003","relation":{},"ISSN":["0065-1281"],"issn-type":[{"value":"0065-1281","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroprotective potential of Aloe arborescens against copper induced neurobehavioral features of Parkinson\u2019s disease in rat","name":"articletitle","label":"Article Title"},{"value":"Acta Histochemica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acthis.2017.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}]}}