{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:47:32Z","timestamp":1782895652196,"version":"3.54.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Urol\u00f3gicas Espa\u00f1olas (English Edition)"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.acuroe.2026.501995","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:04:59Z","timestamp":1779689099000},"page":"501995","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Urinary pH and oncologic outcomes after bacillus calmette\u2013gu\u00e9rin in non-muscle invasive bladder cancer: a retrospective cohort study"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0731-9877","authenticated-orcid":false,"given":"K.","family":"Kayar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Kayar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.B.","family":"Ozdemir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Karabay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Tosun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.I.","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.E.","family":"Yucebas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.acuroe.2026.501995_bib0005","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.eururo.2023.03.029","article-title":"Epidemiology of bladder cancer in 2023: a systematic review of risk factors","volume":"84","author":"Jubber","year":"2023","journal-title":"Eur Urol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0010","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijsu.2018.02.045","article-title":"Maintenance versus non-maintenance intravesical Bacillus Calmette-Guerin instillation for non-muscle invasive bladder cancer: a systematic review and meta-analysis of randomized clinical trials","volume":"52","author":"Chen","year":"2018","journal-title":"Int J Surg"},{"key":"10.1016\/j.acuroe.2026.501995_bib0015","article-title":"The management of Bacillus Calmette-Guerin (BCG) failure in high-risk non-muscle invasive bladder cancer: a review article","volume":"15","author":"Kodera","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.acuroe.2026.501995_bib0020","article-title":"New treatment options for non-muscle-invasive bladder cancer","volume":"45","author":"Filon","year":"2025","journal-title":"Am Soc Clin Oncol Educ Book"},{"key":"10.1016\/j.acuroe.2026.501995_bib0025","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.imlet.2015.07.003","article-title":"Effects of extracellular pH and hypoxia on the function and development of antigen-specific cytotoxic T lymphocytes","volume":"167","author":"Nakagawa","year":"2015","journal-title":"Immunol Lett"},{"key":"10.1016\/j.acuroe.2026.501995_bib0030","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/s42255-022-00730-6","article-title":"Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness","volume":"5","author":"Cheng","year":"2023","journal-title":"Nat Metab"},{"key":"10.1016\/j.acuroe.2026.501995_bib0035","doi-asserted-by":"crossref","first-page":"4922","DOI":"10.1038\/s44318-024-00235-w","article-title":"Acidity suppresses CD8+ T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling","volume":"43","author":"Vuillefroy de Silly","year":"2024","journal-title":"EMBO J"},{"key":"10.1016\/j.acuroe.2026.501995_bib0040","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1158\/1055-9965.EPI-22-0801","article-title":"Urine pH and risk of bladder cancer in Northern New England","volume":"32","author":"Fischer","year":"2023","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.acuroe.2026.501995_bib0045","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00345-025-05648-8","article-title":"Acidic urine as a prognostic factor after intravesical Bacillus Calmette-Guerin induction therapy for nonmuscle-invasive bladder cancer","volume":"43","author":"Ryu","year":"2025","journal-title":"World J Urol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0050","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00345-025-05700-7","article-title":"Relationship between urinary pH and efficacy of Bacillus Calmette-Guerin treatment in patients with carcinoma in situ of the bladder","volume":"43","author":"Yamashita","year":"2025","journal-title":"World J Urol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0055","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1200\/JCO.2015.64.4070","article-title":"Definitions, end points, and clinical trial designs for Non-muscle-invasive bladder cancer: recommendations from the International Bladder Cancer Group","volume":"34","author":"Kamat","year":"2016","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0060","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.eururo.2021.08.010","article-title":"European association of urology guidelines on non-muscle-invasive bladder cancer (Ta, T1, and carcinoma in situ)","volume":"81","author":"Babjuk","year":"2022","journal-title":"Eur Urol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0065","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.eururo.2005.04.013","article-title":"Initial high-grade T1 urothelial cell carcinoma: feasibility and prognostic significance of lamina propria invasion microstaging (T1a\/b\/c) in BCG-treated and BCG-non-treated patients","volume":"48","author":"Orsola","year":"2005","journal-title":"Eur Urol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0070","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1111\/j.1464-410X.2012.10939.x","article-title":"Upstaging of urothelial cancer at the time of radical cystectomy: factors associated with upstaging and its effect on outcome","volume":"110","author":"Turker","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.acuroe.2026.501995_bib0075","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1200\/JCO.2014.57.6967","article-title":"Improving selection criteria for early cystectomy in high-grade t1 bladder cancer: a meta-analysis of 15,215 patients","volume":"33","author":"Martin-Doyle","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acuroe.2026.501995_bib0080","doi-asserted-by":"crossref","first-page":"96117","DOI":"10.18632\/oncotarget.21755","article-title":"Recommended oral sodium bicarbonate administration for urine alkalinization did not affect the concentration of mitomycin-C in non-muscle invasive bladder cancer patients","volume":"8","author":"Seo","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.acuroe.2026.501995_bib0085","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1093\/rheumatology\/keaa668","article-title":"The efficacy and safety of citrate mixture vs sodium bicarbonate on urine alkalization in Chinese primary gout patients with benzbromarone: a prospective, randomized controlled study","volume":"60","author":"Xue","year":"2021","journal-title":"Rheumatology (Oxford)"}],"container-title":["Actas Urol\u00f3gicas Espa\u00f1olas (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173578626001083?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173578626001083?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:14:25Z","timestamp":1782893665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2173578626001083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2173578626001083"],"URL":"https:\/\/doi.org\/10.1016\/j.acuroe.2026.501995","relation":{},"ISSN":["2173-5786"],"issn-type":[{"value":"2173-5786","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary pH and oncologic outcomes after bacillus calmette\u2013gu\u00e9rin in non-muscle invasive bladder cancer: a retrospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Actas Urol\u00f3gicas Espa\u00f1olas (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acuroe.2026.501995","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.acuro.2026.501995","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 AEU. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"501995"}}