{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T11:37:11Z","timestamp":1763552231069,"version":"build-2065373602"},"reference-count":39,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Cardiovascular Diseases"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.acvd.2022.08.004","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T10:14:03Z","timestamp":1666606443000},"page":"627-636","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clustering of patients with inconclusive non-invasive stress testing referred for vasodilator stress cardiovascular magnetic resonance"],"prefix":"10.1016","volume":"115","author":[{"given":"Th\u00e9o","family":"Pezel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Bonnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marine","family":"Kinnel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anouk","family":"Asselin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hovasse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Unterseeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Champagne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Sanguineti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solenn","family":"Toupin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Garot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Garot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.acvd.2022.08.004_bib0200","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics-2019 update: a report from the american heart association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0205","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1016\/j.jacc.2012.07.013","volume":"60","author":"Fihn","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0210","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.acvd.2022.08.004_bib0215","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.jacc.2013.11.052","article-title":"Yield of downstream tests after exercise treadmill testing: a prospective cohort study","volume":"63","author":"Christman","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0220","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.recesp.2017.02.020","article-title":"Inconclusive exercise stress echocardiography in patients with chest pain: prevalence and clinical determinants","volume":"71","author":"Flores-Blanco","year":"2018","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.acvd.2022.08.004_bib0225","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1161\/CIRCULATIONAHA.109.903351","article-title":"Selecting a noninvasive imaging study after an inconclusive exercise test","volume":"122","author":"Blankstein","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0230","doi-asserted-by":"crossref","first-page":"e009986","DOI":"10.1161\/CIRCIMAGING.119.009986","article-title":"Clinical and economic implications of inconclusive noninvasive test results in stable patients with suspected coronary artery disease: insights from the PROMISE trial","volume":"13","author":"Goyal","year":"2020","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0235","doi-asserted-by":"crossref","first-page":"760120","DOI":"10.3389\/fcvm.2021.760120","article-title":"Phenotypic clustering of patients with newly diagnosed coronary artery disease using cardiovascular magnetic resonance and coronary computed tomography angiography","volume":"8","author":"Pezel","year":"2021","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.acvd.2022.08.004_bib0240","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/CIRCULATIONAHA.114.010637","article-title":"Phenomapping for novel classification of heart failure with preserved ejection fraction","volume":"131","author":"Shah","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0245","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1161\/01.CIR.0000047041.66447.29","volume":"107","author":"Gibbons","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0250","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jacc.2014.12.018","volume":"66","author":"Hicks","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0255","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1161\/CIR.0000000000000617","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"138","author":"Thygesen","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0260","doi-asserted-by":"crossref","first-page":"e010599","DOI":"10.1161\/CIRCIMAGING.120.010599","article-title":"Safety and prognostic value of vasodilator stress cardiovascular magnetic resonance in patients with heart failure and reduced ejection fraction","volume":"13","author":"Pezel","year":"2020","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0265","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.jcmg.2020.07.041","article-title":"Feasibility and prognostic value of vasodilator stress perfusion CMR in patients with atrial fibrillation","volume":"14","author":"Pezel","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0270","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1161\/hc0402.102975","article-title":"Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association","volume":"105","author":"Cerqueira","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0275","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1001\/jamacardio.2019.0035","article-title":"Prognostic value of vasodilator stress cardiac magnetic resonance imaging: a multicenter study with 48000 patient-years of follow-up","volume":"4","author":"Heitner","year":"2019","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0280","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.jacc.2019.07.074","article-title":"Cardiac magnetic resonance stress perfusion imaging for evaluation of patients with chest pain","volume":"74","author":"Kwong","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0285","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/eurheartj\/ehi258","article-title":"Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies","volume":"26","author":"Mahrholdt","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.acvd.2022.08.004_bib0290","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1056\/NEJM200011163432003","article-title":"The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction","volume":"343","author":"Kim","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acvd.2022.08.004_bib0295","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/10976640600572889","article-title":"Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance","volume":"8","author":"Maceira","year":"2006","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1016\/j.acvd.2022.08.004_bib0300","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1093\/eurheartj\/ehl336","article-title":"Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance","volume":"27","author":"Maceira","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.acvd.2022.08.004_bib0305","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1161\/CIRCULATIONAHA.107.726711","article-title":"Effects of left bundle-branch block on cardiac structure, function, perfusion, and perfusion reserve: implications for myocardial contrast echocardiography versus radionuclide perfusion imaging for the detection of coronary artery disease","volume":"117","author":"Hayat","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.acvd.2022.08.004_bib0310","first-page":"920","article-title":"Diagnostic accuracy of electrocardiographic ST-segment depression in patients with rapid atrial fibrillation for the prediction of coronary artery disease","volume":"30","author":"Tsigkas","year":"2014","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0315","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0002-8703(92)90695-R","article-title":"Influence of exercise intensity on the presence, distribution, and size of thallium-201 defects","volume":"123","author":"Heller","year":"1992","journal-title":"Am Heart J"},{"key":"10.1016\/j.acvd.2022.08.004_bib0320","doi-asserted-by":"crossref","first-page":"P76","DOI":"10.1186\/1532-429X-18-S1-P76","article-title":"Prognostic value of cardiovascular magnetic resonance stress perfusion imaging in patients with atrial fibrillation","volume":"18","author":"Bigvava","year":"2016","journal-title":"Journal of Cardiovascular Magnetic Resonance"},{"key":"10.1016\/j.acvd.2022.08.004_bib0325","first-page":"802","article-title":"Functional testing after coronary artery bypass graft surgery: a meta-analysis","volume":"19","author":"Chin","year":"2003","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0330","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1056\/NEJMoa1709118","article-title":"Rivaroxaban with or without aspirin in stable cardiovascular disease","volume":"377","author":"Eikelboom","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acvd.2022.08.004_bib0335","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory therapy with canakinumab for atherosclerotic disease","volume":"377","author":"Ridker","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acvd.2022.08.004_bib0340","first-page":"991","article-title":"Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: a meta-analysis","volume":"38","author":"Danad","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.acvd.2022.08.004_bib0345","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jacc.2013.03.080","article-title":"Prognostic value of stress cardiac magnetic resonance imaging in patients with known or suspected coronary artery disease: a systematic review and meta-analysis","volume":"62","author":"Lipinski","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0350","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.jacc.2007.06.030","article-title":"Diagnostic performance of stress cardiac magnetic resonance imaging in the detection of coronary artery disease: a meta-analysis","volume":"50","author":"Nandalur","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0355","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/ehjci\/jeaa316","article-title":"Prognostic value of vasodilator stress perfusion CMR in patients with previous coronary artery bypass graft","volume":"22","author":"Kinnel","year":"2021","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0360","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1016\/j.jcmg.2021.04.021","article-title":"Prognostic value of vasodilator stress perfusion cardiovascular magnetic resonance in patients with prior myocardial infarction","volume":"14","author":"Pezel","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0365","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jcmg.2019.03.002","article-title":"Prognostic implications of blunted feature-tracking global longitudinal strain during vasodilator cardiovascular magnetic resonance stress imaging","volume":"13","author":"Romano","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0370","doi-asserted-by":"crossref","first-page":"765961","DOI":"10.3389\/fcvm.2021.765961","article-title":"Fast-strain encoded cardiac magnetic resonance during vasodilator perfusion stress testing","volume":"8","author":"Steen","year":"2021","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.acvd.2022.08.004_bib0375","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.jcmg.2017.02.006","article-title":"Stress perfusion CMR in patients with known and suspected CAD: prognostic value and optimal ischemic threshold for revascularization","volume":"10","author":"Vincenti","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0380","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.jcmg.2011.04.015","article-title":"Stress myocardial perfusion imaging by CMR provides strong prognostic value to cardiac events regardless of patient's sex","volume":"4","author":"Coelho-Filho","year":"2011","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.acvd.2022.08.004_bib0385","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/j.jacc.2012.05.041","article-title":"Cardiac outcomes with submaximal normal stress echocardiography: a meta-analysis","volume":"60","author":"Makani","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.acvd.2022.08.004_bib0390","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1915922","article-title":"Initial invasive or conservative strategy for stable coronary disease","volume":"382","author":"Maron","year":"2020","journal-title":"N Engl J Med"}],"container-title":["Archives of Cardiovascular Diseases"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875213622001954?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875213622001954?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:48:08Z","timestamp":1761745688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875213622001954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S1875213622001954"],"URL":"https:\/\/doi.org\/10.1016\/j.acvd.2022.08.004","relation":{},"ISSN":["1875-2136"],"issn-type":[{"type":"print","value":"1875-2136"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clustering of patients with inconclusive non-invasive stress testing referred for vasodilator stress cardiovascular magnetic resonance","name":"articletitle","label":"Article Title"},{"value":"Archives of Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acvd.2022.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}