{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:36:50Z","timestamp":1776134210958,"version":"3.50.1"},"reference-count":75,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.ad.2011.10.008","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T19:26:55Z","timestamp":1330457215000},"page":"679-693","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["S\u00edfilis cong\u00e9nita en el siglo xxi"],"prefix":"10.1016","volume":"103","author":[{"given":"C.","family":"Rodr\u00edguez-Cerdeira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.G.","family":"Silami-Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ad.2011.10.008_bib0005","first-page":"133","article-title":"A clinical look at the morbus gallicus","volume":"2","author":"Morton","year":"1985","journal-title":"Eur J Sex Trans Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0010","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1136\/sti.77.5.322","article-title":"The syphilis enigma: the riddle resolved","volume":"77","author":"Morton","year":"2001","journal-title":"Sex Trans Infec"},{"key":"10.1016\/j.ad.2011.10.008_bib0015","series-title":"Historia de la Dermatolog\u00eda. 1a ed","author":"Sierra","year":"1994"},{"key":"10.1016\/j.ad.2011.10.008_bib0020","series-title":"Venereolog\u00eda: aspectos epidemiol\u00f3gicos y cl\u00ednicos de las infecciones transmitidas por v\u00eda sexual","first-page":"63","article-title":"S\u00edfilis cong\u00e9nita","author":"Moreno","year":"2005"},{"key":"10.1016\/j.ad.2011.10.008_bib0025","first-page":"402","article-title":"Economic and programmatic aspects of congenital syphilis prevention","volume":"82","author":"Schmid","year":"2004","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ad.2011.10.008_bib0030","series-title":"Campos de Oliveira E et al. Eliminaci\u00f3n mundial de la s\u00edfilis cong\u00e9nita: fundamentos y estrategia para la acci\u00f3n","author":"Ballard","year":"2008"},{"key":"10.1016\/j.ad.2011.10.008_bib0035","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1590\/S1020-49892004000900012","article-title":"S\u00edfilis materna y s\u00edfilis cong\u00e9nita en Am\u00e9rica Latina: un problema grave de soluci\u00f3n sencilla","volume":"16","author":"Valderrama","year":"2004","journal-title":"Rev Panam Salud Publica\/Pan Am J Public Health"},{"key":"10.1016\/j.ad.2011.10.008_bib0040","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2807\/ese.14.09.19134-en","article-title":"Antenatal screening and prevalence of infection: surveillance in London, 2000-2007","volume":"14","author":"Giraudon","year":"2009","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ad.2011.10.008_bib0045","first-page":"E050519.3","article-title":"Sexually transmitted infections situation is a cause for concern in Poland","volume":"10","author":"Rudnicka","year":"2005","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ad.2011.10.008_bib0050","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2807\/esm.09.12.00496-en","article-title":"Syphilis and gonorrhoea in the Czech Republic","volume":"9","author":"Z\u00e1kouck\u00e1","year":"2004","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ad.2011.10.008_bib0055","first-page":"1","article-title":"Congenital syphilis in Italy: a multicentre study","volume":"24","author":"Tridapalli","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal"},{"key":"10.1016\/j.ad.2011.10.008_bib0060","series-title":"Eliminaci\u00f3n de s\u00edfilis cong\u00e9nita en Am\u00e9rica Latina y el Caribe: marco de referencia para su implementaci\u00f3n","year":"2005"},{"key":"10.1016\/j.ad.2011.10.008_bib0065","series-title":"Hoja informativa sobre s\u00edfilis cong\u00e9nita.","year":"2004"},{"key":"10.1016\/j.ad.2011.10.008_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/sti.2005.019349","article-title":"Congenital syphilis in the United Kingdom. Are we prepared?","volume":"82","author":"Simms","year":"2006","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ad.2011.10.008_bib0075","first-page":"248","article-title":"Actualizaci\u00f3n en s\u00edfilis cong\u00e9nita","volume":"6","author":"Rodr\u00edguez-Cerdeira","year":"2003","journal-title":"Rev Int Dermatol Dermocosmet Clin"},{"key":"10.1016\/j.ad.2011.10.008_bib0080","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1525-1470.2010.01147.x","article-title":"Congenital syphilis, case report and epidemiologic features in Spain","volume":"27","author":"Sendagorta","year":"2010","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.ad.2011.10.008_bib0085","first-page":"36","article-title":"Sexually transmitted disease treatment guidelines","volume":"59","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.ad.2011.10.008_bib0090","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2807\/esm.09.12.00491-en","article-title":"A multilevel approach to understanding the resurgence and evolution of infectious syphilis in Western Europe","volume":"9","author":"Fenton","year":"2004","journal-title":"Euro Suveill"},{"key":"10.1016\/j.ad.2011.10.008_bib0095","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/01.olq.0000204916.91780.d9","article-title":"Syphilis management in St. Petersburg, Russia: 1995- 2001","volume":"33","author":"Yakubovsky","year":"2006","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0100","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/sti.79.2.106","article-title":"Congenital Syphilis Investigation Team. Congenital syphilis in the Russian Federation: magnitude, determinants, and consequences","volume":"79","author":"Tikhonova","year":"2003","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ad.2011.10.008_bib0105","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/01.OLQ.0000109516.47951.B8","article-title":"Congenital Syphilis Investigation Team. Congenital syphilis in Russia: the value of counting epidemiologic cases and clinical cases","volume":"31","author":"Salakhov","year":"2004","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0110","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1258\/0956462011924065","article-title":"European guideline for the management of syphilis","volume":"12","author":"Goh","year":"2001","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.ad.2011.10.008_bib0115","series-title":"UgandaHIV\/AIDS Sero-behavioural Survey 2004-2005","year":"2006"},{"key":"10.1016\/j.ad.2011.10.008_bib0120","series-title":"Enqu\u00eate D\u00e9mographique et de Sant\u00e9, Madagascar 2003-2004: Rapport de synth\u00e8se","year":"2005"},{"key":"10.1016\/j.ad.2011.10.008_bib0125","series-title":"Zambia demographic and health survey 2001-2002","year":"2003"},{"key":"10.1016\/j.ad.2011.10.008_bib0130","first-page":"65","article-title":"Serological screening for sexually transmitted infections in pregnancy: is there any value in re-screening for HIV and syphilis at the time of delivery","volume":"71","author":"Qolohle","year":"1995","journal-title":"Genitourinary Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0135","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/01.olq.0000261456.09797.1b","article-title":"The need and plan for global elimination of congenital syphilis","volume":"34","author":"Schmid","year":"2007","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0140","series-title":"Venereolog\u00eda: aspectos epidemiol\u00f3gicos y cl\u00ednicos de las infecciones transmitidas por v\u00eda sexual","first-page":"51","article-title":"S\u00edfilis adquirida","author":"Rodr\u00edguez-Cerdeira","year":"2005"},{"key":"10.1016\/j.ad.2011.10.008_bib0145","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/1471-2180-8-76","article-title":"Complete genome sequence of Treponema pallidum ssp. pallidum strain SS14 determined with oligonucleotide arrays","volume":"8","author":"Matejkov\u00e1","year":"2008","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.ad.2011.10.008_bib0150","doi-asserted-by":"crossref","first-page":"3608","DOI":"10.1073\/pnas.85.10.3608","article-title":"Treponema pallidum invades intercellular junction of endothelial cell monolayers","volume":"85","author":"Thomas","year":"1988","journal-title":"Proc Natl Acad Sci (USA)"},{"key":"10.1016\/j.ad.2011.10.008_bib0155","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/infdis\/165.3.484","article-title":"Virulent Treponema pallidum activates human vascular endothelial cells","volume":"165","author":"Riley","year":"1992","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0160","first-page":"890","article-title":"Identification of Treponema pallidum in amniotoc fluid and fetal blood from pregnancies complicated by congenital syphilis","volume":"78","author":"Wendel","year":"1991","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ad.2011.10.008_bib0165","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/(SICI)1097-0223(199702)17:2<119::AID-PD39>3.0.CO;2-T","article-title":"In utero infection with Treponema pallidum in early pregnancy","volume":"17","author":"Nathan","year":"1997","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ad.2011.10.008_bib0170","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1258\/0956462991914690","article-title":"Update on the treatment of sexually transmitted infections in pregnancy-1","volume":"10","author":"Brocklehurst","year":"1999","journal-title":"Int J STD & AIDS"},{"key":"10.1016\/j.ad.2011.10.008_bib0175","first-page":"967","article-title":"Examination of amniotic fluid in diagnosing congenital syphilis with fetal death","volume":"6","author":"Wendel","year":"1989","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ad.2011.10.008_bib0180","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/sti.76.2.73","article-title":"Syphilis in pregnancy","volume":"76","author":"Gen\u00e7","year":"2000","journal-title":"Sex Transm Inf"},{"key":"10.1016\/j.ad.2011.10.008_bib0185","first-page":"329","article-title":"Statistics on syphilis cases observed for the first time in the dermatologic clinic of the University of Barcelona in 1963-1964","volume":"56","author":"Vilanova","year":"1965","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2011.10.008_bib0190","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000052954","article-title":"Clinical and epidemiological features in pregnant women: the course and outcome of pregnancy","volume":"52","author":"Mavrov","year":"2001","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ad.2011.10.008_bib0195","first-page":"101","article-title":"Multiple osteochondritis due to prenatal syphilis","volume":"58","author":"Mercadal-Peyri","year":"1967","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2011.10.008_bib0200","first-page":"271","article-title":"Current clinical aspects of syphilis. Apropos of the frequency of atypical clinical forms","volume":"72","author":"Capdevila","year":"1981","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2011.10.008_bib0205","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1086\/321904","article-title":"Pathogenesis of maternal-fetal syphilis revisited","volume":"33","author":"Wicher","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0210","first-page":"150","article-title":"Syphilis maternelle et congenitale","volume":"27","author":"Narducci","year":"1998","journal-title":"J Gyneol Obstet Biol Reprod"},{"key":"10.1016\/j.ad.2011.10.008_bib0215","series-title":"Sexually Transmitted Diseases","first-page":"1165","article-title":"Congenital syphilis","author":"Radolf","year":"1999"},{"key":"10.1016\/j.ad.2011.10.008_bib0220","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.siny.2007.01.019","article-title":"Congenital syphilis: A continuing but neglected problem","volume":"12","author":"Walker","year":"2007","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0225","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/BF02026670","article-title":"Pulmonary changes in congenital syphilis","volume":"21","author":"Austin","year":"1991","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.ad.2011.10.008_bib0230","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/S0001-7310(08)74770-7","article-title":"P\u00e9nfigo sifil\u00edtico: \u00bfpasado, presente o futuro","volume":"99","author":"P\u00e9rez-Pelegay","year":"2008","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2011.10.008_bib0235","doi-asserted-by":"crossref","first-page":"635","DOI":"10.3928\/00904481-20100922-01","article-title":"Blisters and pustules in the newborn","volume":"39","author":"Antaya","year":"2010","journal-title":"Pediatr Ann"},{"key":"10.1016\/j.ad.2011.10.008_bib0240","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jgyn.2007.08.006","article-title":"El Guindi W, Helou G, Alassas N et al. Syphilis and pregnancy","volume":"37","author":"Carles","year":"2008","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.ad.2011.10.008_bib0245","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1034\/j.1600-0412.2000.079005371.x","article-title":"Epidemiology of fetal death in Latin America","volume":"79","author":"Conde-Agudelo","year":"2000","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ad.2011.10.008_bib0250","first-page":"203","article-title":"Lineal cicatrix of the face as a clinical stigma in a case of syphilis congenital tarda","volume":"56","author":"Vilanova","year":"1965","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2011.10.008_bib0255","first-page":"1507","article-title":"Osteoarticular manifestations of late congenital syphilis","volume":"37","author":"Abdelmoula","year":"2008","journal-title":"Presse Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0260","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1542\/pir.20.5.160","article-title":"Syphilis","volume":"20","author":"Darville","year":"1999","journal-title":"Pediatr Rev"},{"key":"10.1016\/j.ad.2011.10.008_bib0265","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1111\/j.1468-3083.2006.01739.x","article-title":"Late congenital syphilis presenting as deletion of uvula and cardiovascular disease","volume":"20","author":"Liu","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.ad.2011.10.008_bib0270","first-page":"947","article-title":"Fetal syphilis: clinical and laboratory characteristics","volume":"97","author":"Hollier","year":"2001","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ad.2011.10.008_bib0275","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1055\/s-2007-993933","article-title":"Nonimmune hydrops fetalis due to congenital syphilis associated with negative intrapartum maternal serology screening","volume":"15","author":"Levine","year":"1998","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ad.2011.10.008_bib0280","doi-asserted-by":"crossref","first-page":"49","DOI":"10.7863\/jum.1992.11.1.49","article-title":"Congenital syphilis associated with dilation of fetal small bowel. A case report","volume":"11","author":"Satin","year":"1992","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0285","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s12519-010-0028-z","article-title":"Congenital syphilis: still a serious, under-diagnosed threat for children in resource-poor countries","volume":"6","author":"Kr\u00fcger","year":"2010","journal-title":"World J Pediatr"},{"key":"10.1016\/j.ad.2011.10.008_bib0290","doi-asserted-by":"crossref","first-page":"S200","DOI":"10.1086\/342108","article-title":"Treatment of syphilis in pregnancy and prevention of congenital syphilis","volume":"35 Suppl 2","author":"Wendel","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0295","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1001\/archpedi.155.2.140","article-title":"Congenital syphilis surveillance and newborn evaluation in a low -incidence state","volume":"155","author":"Martin","year":"2001","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0300","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1258\/ijsa.2008.008510","article-title":"IUSTI: 2008 European Guidelines on the Management of Syphilis","volume":"20","author":"French","year":"2009","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.ad.2011.10.008_bib0305","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1097\/00006454-199410000-00001","article-title":"Congenital syphilis: evaluation and management of neonates born to mothers with reactive serologic tests for syphilis","volume":"13","author":"Stoll","year":"1994","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.ad.2011.10.008_bib0310","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10096-010-0900-8","article-title":"A review of diagnostic tests for congenital syphilis in newborns","volume":"29","author":"Herremans","year":"2010","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0315","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/01.OLQ.0000109941.60065.65","article-title":"Evaluation of a Treponema pallidum-specific IgM enzyme immunoassay and Treponema pallidum western blot antibody detection in the diagnosis of maternal and congenital syphilis","volume":"31","author":"Rawstron","year":"2004","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0320","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1749-6632.1975.tb29159.x","article-title":"The specificity of fetal IgM: antibody or anti-antibody","volume":"254","author":"Reimer","year":"1975","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.ad.2011.10.008_bib0325","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0046-8177(96)90110-0","article-title":"Diagnosis of congenital syphilis from placental examination: comparison of histopathology, Steiner stain, and polymerase chain reaction for Treponema pallidum DNA","volume":"27","author":"Genest","year":"1996","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ad.2011.10.008_bib0330","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1056\/NEJMoa012684","article-title":"Central nervous system infection in congenital syphilis","volume":"346","author":"Michelow","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0335","series-title":"Special Programme for Research and Training in Tropical Diseases Laboratory-based evaluation of rapid syphilis diagnostics: results from 8 SDI sites, TDR\/SDI\/DE\/03. 1","year":"2003"},{"key":"10.1016\/j.ad.2011.10.008_bib0340","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2471\/BLT.04.018663","article-title":"Comparison of the diagnostic accuracy of a rapid immunochromatographic test and the rapid plasma reagin test for antenatal syphilis screening in Mozambique","volume":"84","author":"Montoya","year":"2006","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ad.2011.10.008_bib0345","doi-asserted-by":"crossref","first-page":"6811","DOI":"10.1128\/IAI.70.12.6811-6816.2002","article-title":"Immunization with the N-terminal portion of Treponema pallidum repeat protein K attenuates syphilitic lesion development in the rabbit model","volume":"70","author":"Morgan","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.ad.2011.10.008_bib0350","series-title":"IUSTI\/WHO Conference on STI","article-title":"Treatment of Syphilis in Europe. 2004","author":"Parkes","year":"2004"},{"key":"10.1016\/j.ad.2011.10.008_bib0355","first-page":"1405","article-title":"Detecting high risk pregnancy","volume":"59","author":"Doret","year":"2009","journal-title":"Rev Prat"},{"key":"10.1016\/j.ad.2011.10.008_bib0360","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.olq.0000148297.48590.d8","article-title":"Effectiveness of syphilis treatment using azithromycin and\/or benzathine penicillin in Rakai, Uganda","volume":"32","author":"Kiddugavu","year":"2005","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2011.10.008_bib0365","first-page":"204","article-title":"Azithromycin versus penicillin for early syphilis","volume":"354","author":"Riedner","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ad.2011.10.008_bib0370","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1586\/14760584.5.1.67","article-title":"Progress towards an effective syphilis vaccine: the past, present and future","volume":"5","author":"Cullen","year":"2006","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.ad.2011.10.008_bib0375","series-title":"Global strategy for the prevention and control of sexually transmitted infections 2006-2015","year":"2006"}],"container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731011005278?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731011005278?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:59:37Z","timestamp":1757552377000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001731011005278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":75,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0001731011005278"],"URL":"https:\/\/doi.org\/10.1016\/j.ad.2011.10.008","relation":{},"ISSN":["0001-7310"],"issn-type":[{"value":"0001-7310","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"S\u00edfilis cong\u00e9nita en el siglo xxi","name":"articletitle","label":"Article Title"},{"value":"Actas Dermo-Sifiliogr\u00e1ficas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ad.2011.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Espa\u00f1a, S.L. y AEDV. All rights reserved.","name":"copyright","label":"Copyright"}]}}