{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:25:48Z","timestamp":1772223948854,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.ad.2013.12.010","type":"journal-article","created":{"date-parts":[[2014,3,12]],"date-time":"2014-03-12T07:49:53Z","timestamp":1394610593000},"page":"840-846","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Actualizaci\u00f3n en la dermatitis de contacto al\u00e9rgica por metilcloroisotiazolinona\/metilisotiazolinona y metilisotiazolinona"],"prefix":"10.1016","volume":"105","author":[{"given":"M.","family":"Leiva-Salinas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Franc\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"Silvestre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ad.2013.12.010_bib0005","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1111\/j.1365-2133.2011.10253.x","article-title":"Contact allergy to preservatives. Analysis of IVDK data 1996-2009","volume":"164","author":"Schnuch","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.ad.2013.12.010_bib0010","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1600-0536.2010.01754.x","article-title":"Methylisothiazolinone, an emerging allergen in cosmetics?","volume":"63","author":"Garcia-Gavin","year":"2010","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0015","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1600-0536.2012.02157.x","article-title":"Recent increase in allergic reactions to methylchloroisothiazolinone\/methylisothiazolinone: Is methylisothiazolinone the culprit?","volume":"67","author":"Geier","year":"2012","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/cod.12149","article-title":"Methylisothiazolinone contact allergy-a growing epidemic","volume":"69","author":"Lundov","year":"2013","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0025","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/cod.12150","article-title":"Recommendation to include methylisothiazolinone in the European baseline patch test series-on behalf of the European Society of Contact Dermatitis and the European Environmental and Contact Dermatitis Research Group","volume":"69","author":"Bruze","year":"2013","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0030","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1600-0536.2010.01700.x","article-title":"Delayed hypersensitivity to methylchloroisothiazolinone\/methylisothiazolinone not detected by the baseline series of the Spanish group","volume":"62","author":"Cuesta","year":"2010","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0035","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.1600-0536.2009.01509.x","article-title":"Identifying the optimal patch test concentration for methylchloroisothiazolinone and methylisothiazolinone","volume":"60","author":"Davies","year":"2009","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0040","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.tiv.2009.01.014","article-title":"Mechanistic assessment of peptide reactivity assay to predict skin allergens with Kathon CG isothiazolinones","volume":"23","author":"Mutschler","year":"2009","journal-title":"Toxicol In Vitro"},{"key":"10.1016\/j.ad.2013.12.010_bib0045","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1111\/j.1365-2133.2011.10523.x","article-title":"Methylisothiazolinone contact allergy: A review","volume":"165","author":"Lundov","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.ad.2013.12.010_bib0050","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/cod.12167","article-title":"Methylisothiazolinone is categorised as a strong sensitiser in the murine local lymph node assay","volume":"69","author":"Roberts","year":"2013","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0055","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-0536.2012.02075.x","article-title":"Methylchloroisothiazolinone\/methylisothiazolinone contact sensitization: Diverging trends in subgroups of IVDK patients in a period of 19 years","volume":"67","author":"Uter","year":"2012","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0060","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1600-0536.2011.01939.x","article-title":"Risk of sensitization to preservatives estimated on the basis of patch test data and exposure, according to a sample of 3,541 leave-on products","volume":"65","author":"Schnuch","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0065","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1600-0536.2011.01968.x","article-title":"Non-fragrance allergens in specific cosmetic products","volume":"65","author":"Travassos","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0070","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1600-0536.2009.01647.x","article-title":"Contact allergens and irritants in household washing and cleaning products","volume":"61","author":"Magnano","year":"2009","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0075","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1600-0536.2012.02074.x","article-title":"Occupational contact dermatitis in painters: An analysis of patch test data from the Danish Contact Dermatitis Group","volume":"67","author":"Mose","year":"2012","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0080","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.0105-1873.2005.00629.x","article-title":"Preservatives in registered chemical products","volume":"53","author":"Flyvholm","year":"2005","journal-title":"Contact Dermatitis"},{"issue":"Suppl 1","key":"10.1016\/j.ad.2013.12.010_bib0085","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1600-0536.2011.02004_4.x","article-title":"The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals. Part III","volume":"66","author":"Thyssen","year":"2012","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0090","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0536.2010.01811.x","article-title":"Contact sensitization to methylisothiazolinone in Finland--a multicentre study","volume":"64","author":"Ackermann","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0095","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0001-7310(04)79199-1","article-title":"Estudio epidemiol\u00f3gico de la dermatitis al\u00e9rgica de contacto en Espa\u00f1a (2001)","volume":"95","author":"Garc\u00eda-Bravo","year":"2004","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2013.12.010_bib0100","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1600-0536.2011.01924.x","article-title":"Two cases of airborne allergic contact dermatitis caused by methylisothiazolinone in paint","volume":"65","author":"Lundov","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0105","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ad.2010.06.029","article-title":"Sensibilizaci\u00f3n a metil-cloro-isotiazolinona\/metilisotiazolinona tras quemadura por exposici\u00f3n profesional masiva accidental","volume":"102","author":"Monsalvez","year":"2011","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.ad.2013.12.010_bib0110","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1600-0536.2011.01901.x","article-title":"Methylisothiazolinone contact allergy and dose-response relationships","volume":"64","author":"Lundov","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.ad.2013.12.010_bib0115","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1001\/archdermatol.2010.114","article-title":"The hazards of moist toilet paper: Allergy to the preservative methylchloroisothiazolinone\/methylisothiazolinone","volume":"146","author":"Gardner","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.ad.2013.12.010_bib0120","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ad.2011.01.004","article-title":"Utilidad de las pruebas epicut\u00e1neas en el eczema de manos en ni\u00f1os: estudio comparativo con el eczema en la edad pedi\u00e1trica y con el eczema de manos en adultos","volume":"102","author":"Toledo","year":"2011","journal-title":"Actas Dermosifiliogr"}],"container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731014000209?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731014000209?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T01:03:12Z","timestamp":1757552592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001731014000209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":24,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0001731014000209"],"URL":"https:\/\/doi.org\/10.1016\/j.ad.2013.12.010","relation":{},"ISSN":["0001-7310"],"issn-type":[{"value":"0001-7310","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Actualizaci\u00f3n en la dermatitis de contacto al\u00e9rgica por metilcloroisotiazolinona\/metilisotiazolinona y metilisotiazolinona","name":"articletitle","label":"Article Title"},{"value":"Actas Dermo-Sifiliogr\u00e1ficas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ad.2013.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Espa\u00f1a, S.L.U. y AEDV. All rights reserved.","name":"copyright","label":"Copyright"}]}}