{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T14:24:19Z","timestamp":1781706259518,"version":"3.54.5"},"reference-count":10,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.ad.2018.04.010","type":"journal-article","created":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T17:33:22Z","timestamp":1558719202000},"page":"700-701","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hiperpigmentaci\u00f3n inducida por levofloxacino"],"prefix":"10.1016","volume":"110","author":[{"given":"M.","family":"Castellanos-Gonz\u00e1lez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.L.","family":"Gonz\u00e1lez Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Gonz\u00e1lez-Granda Villalobos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ad.2018.04.010_bib0055","doi-asserted-by":"crossref","first-page":"666","DOI":"10.12659\/AJCR.899823","article-title":"Levofloxacin induced toxic epidermal necrolysis: successful therapy with omalizumab (Anti-IgE) and pulse prednisolone","volume":"17","author":"Uzun","year":"2016","journal-title":"Am J Case Rep."},{"key":"10.1016\/j.ad.2018.04.010_bib0060","doi-asserted-by":"crossref","first-page":"547","DOI":"10.2515\/therapie\/2015046","article-title":"DRESS syndrome following levofloxacin exposure with positive patch-test","volume":"70","author":"Charfi","year":"2015","journal-title":"Therapie."},{"key":"10.1016\/j.ad.2018.04.010_bib0065","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1177\/0091270011405501","article-title":"Fixed drug eruption: levofloxacin, another culprit drug","volume":"52","author":"Ben Fredj","year":"2012","journal-title":"J Clin Pharmacol."},{"key":"10.1016\/j.ad.2018.04.010_bib0070","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.4081\/idr.2012.e11","article-title":"Cutaneous leukocytoclastic vasculitis associated with levofloxacin therapy","volume":"4","author":"Blyth","year":"2012","journal-title":"Infect Dis Rep."},{"key":"10.1016\/j.ad.2018.04.010_bib0075","doi-asserted-by":"crossref","first-page":"ofv107","DOI":"10.1093\/ofid\/ofv107","article-title":"Minocycline-induced cutaneous hyperpigmentation in an orthopedic patient population","volume":"3","author":"Hanada Y1","year":"2016","journal-title":"Open Forum Infect Dis."},{"key":"10.1016\/j.ad.2018.04.010_bib0080","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0140-6736(14)61800-6","article-title":"Blue-black eyes and legs","volume":"385","author":"Gauer","year":"2015","journal-title":"Lancet."},{"key":"10.1016\/j.ad.2018.04.010_bib0085","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.annder.2017.05.017","article-title":"Skin pigmentation induced by meropenem and levofloxacin","volume":"144","author":"Garval","year":"2017","journal-title":"Ann Dermatol Venereol."},{"key":"10.1016\/j.ad.2018.04.010_bib0090","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1001\/archderm.143.11.1441-b","article-title":"Blue-black pigmentation of legs and arms in a 68-year-old woman","volume":"143","author":"L\u00f3pez-Pesta\u00f1a","year":"2007","journal-title":"Arch Dermatol."},{"key":"10.1016\/j.ad.2018.04.010_bib0095","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/archderm.1995.01690190112032","article-title":"Blue-black pigmentation of the legs associated with pefloxacin therapy","volume":"131","author":"Le Cleach","year":"1995","journal-title":"Arch Dermatol."},{"key":"10.1016\/j.ad.2018.04.010_bib0100","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1097\/DAD.0000000000000920","article-title":"Mucocutaneous hyperpigmentation in a patient with a history of both minocycline and silver ingestion","volume":"39","author":"Fernandez-Flores","year":"2017","journal-title":"Am J Dermatopathol."}],"container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731019300596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731019300596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T01:09:09Z","timestamp":1757552949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001731019300596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S0001731019300596"],"URL":"https:\/\/doi.org\/10.1016\/j.ad.2018.04.010","relation":{},"ISSN":["0001-7310"],"issn-type":[{"value":"0001-7310","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hiperpigmentaci\u00f3n inducida por levofloxacino","name":"articletitle","label":"Article Title"},{"value":"Actas Dermo-Sifiliogr\u00e1ficas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ad.2018.04.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 AEDV. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}