{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:16:21Z","timestamp":1792707381811,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.ad.2019.03.014","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T08:17:18Z","timestamp":1570090638000},"page":"841-849","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Las caracter\u00edsticas epidemiol\u00f3gicas y cl\u00ednicas de la epidemia de s\u00edfilis en Barcelona"],"prefix":"10.1016","volume":"110","author":[{"given":"M.","family":"Arando","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Caballero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Curran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Armengol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Barber\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vall-Mayans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ad.2019.03.014_bib0155","unstructured":"European Centre for Disease Prevention and Control. Sexually transmitted infections in Europe 2013. Stockholm: ECDC; 2015 [consultado 27 Feb 2017]. Disponible en: http:\/\/ecdc.europa.eu\/en\/publications\/Publications\/sexual-transmitted-infections-europe-surveillance-report-2013.pdf"},{"key":"10.1016\/j.ad.2019.03.014_bib0160","unstructured":"Centre d\u2019Estudi Epidemiol\u00f2gics sobre Infeccions de Transmissi\u00f3 Sexual i Sida de Catalunya (CEEISCAT). CEEISCAT Epidemiological Report 2015. Integrated Surveillance System For STI and HIV in Catalonia (SIVES) Technical document N.\u00b0 22. Barcelona: CEEISCAT; 2015 consultado 27 Feb 2017]. Disponible en: http:\/\/www.ceeiscat.cat\/documents\/sives2015_ENG.pdf"},{"key":"10.1016\/j.ad.2019.03.014_bib0165","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1157\/13083877","article-title":"Reemergence of infectious syphilis among homosexual men and HIV coinfection in Barcelona, 2002-2003","volume":"126","author":"Vall-Mayans","year":"2006","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.ad.2019.03.014_bib0170","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1128\/jcm.34.1.49-54.1996","article-title":"Simultaneous PCR detection of Haemophilus ducreyi Treponema pallidum, and herpes simplex virus types 1 and 2 from genital ulcers","volume":"34","author":"Orle","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ad.2019.03.014_bib0175","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1111\/jdv.12734","article-title":"2014 European guideline on the management of syphilis","volume":"28","author":"Janier","year":"2014","journal-title":"J Eur Acad Dermatology Venereol"},{"issue":"Suppl 1","key":"10.1016\/j.ad.2019.03.014_bib0180","doi-asserted-by":"crossref","first-page":"i14","DOI":"10.1136\/sti.78.suppl_1.i14","article-title":"The geographical and temporal evolution of sexually transmitted disease epidemics","volume":"78","author":"Garnett","year":"2002","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ad.2019.03.014_bib0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0159309","article-title":"Syphilis trends among men who have sex with men in the United States and Western Europe: A systematic review of trend studies published between 2004 and 2015","volume":"11","author":"Abara","year":"2016","journal-title":"PLOS ONE"},{"key":"10.1016\/j.ad.2019.03.014_bib0190","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/01.olq.0000140009.28121.0f","article-title":"A case-control study of syphilis among men who have sex with men in New York City. Association with HIV infection","volume":"31","author":"Paz-Bailey","year":"2004","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0195","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.2105\/AJPH.2014.302346","article-title":"Drug use sexual risk, and syndemic production among men who have sex with men who engage in group sexual encounters","volume":"105","author":"Hirshfield","year":"2015","journal-title":"Am J Public Health"},{"key":"10.1016\/j.ad.2019.03.014_bib0200","doi-asserted-by":"crossref","first-page":"388","DOI":"10.2105\/AJPH.92.3.388","article-title":"Impact of highly active antiretroviral treatment on HIV seroincidence among men who have sex with men: San Francisco","volume":"92","author":"Katz","year":"2002","journal-title":"Am J Public Health"},{"key":"10.1016\/j.ad.2019.03.014_bib0205","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/OLQ.0b013e3181f2ebe1","article-title":"Changing patterns of sexual risk behavior among London gay men: 1998-2008","volume":"38","author":"Lattimore","year":"2011","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0210","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1186\/s12889-015-2344-7","article-title":"Epidemiology of infections by HIV syphilis, gonorrhea and lymphogranuloma venereum in Barcelona city: A population-based incidence study","volume":"15","author":"Mart\u00ed-Pastor","year":"2015","journal-title":"BMC Public Health"},{"key":"10.1016\/j.ad.2019.03.014_bib0215","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3201\/eid2201.151331","article-title":"Increase in sexually transmitted infections among men who have sex with men England, 2014","volume":"22","author":"Mohammed","year":"2016","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0220","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/QAI.0b013e3181e583bf","article-title":"Frequent screening for syphilis as part of HIV monitoring increases the detection of early asymptomatic syphilis among HIV-positive homosexual men","volume":"55","author":"Bissessor","year":"2010","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.ad.2019.03.014_bib0225","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/sti.75.1.3","article-title":"From epidemiological synergy to public health policy and practice: The contribution of other sexually transmitted diseases to sexual transmission of HIV infection","volume":"75","author":"Fleming","year":"1999","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ad.2019.03.014_bib0230","unstructured":"Centers for Disease Control and Prevention. Primary and secondary syphilis \u2014United States, 2005-2013. MM WR 2014;63(18):402-406."},{"key":"10.1016\/j.ad.2019.03.014_bib0235","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/cid\/civ289","article-title":"The high risk of an HIV diagnosis following a diagnosis of syphilis: A population-level analysis of New York City men","volume":"61","author":"Pathela","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0240","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/01.olq.0000187224.10428.31","article-title":"Understanding recent increases in the incidence of sexually transmitted infections in men having sex with men: Changes in risk behavior from risk avoidance to risk reduction","volume":"33","author":"Marcus","year":"2006","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0245","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11904-013-0194-4","article-title":"Social networks, sexual networks and HIV risk in men who have sex with men","volume":"11","author":"Amirkhanian","year":"2014","journal-title":"Curr VIH\/AIDS Rep"},{"key":"10.1016\/j.ad.2019.03.014_bib0250","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJM199707313370504","article-title":"A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection","volume":"337","author":"Rolfs","year":"1997","journal-title":"New Engl J Med"},{"key":"10.1016\/j.ad.2019.03.014_bib0255","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/sti.2006.021402","article-title":"Serological response to syphilis treatment in HIV-positive and HIV-negative patients attending sexually transmitted diseases clinics","volume":"83","author":"Ghanem","year":"2007","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ad.2019.03.014_bib0260","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1093\/cid\/cit146","article-title":"Syphilis treatment response among HIV-discordant couples in Zambia and Rwanda","volume":"56","author":"Dionne-Odom","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0265","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1093\/cid\/cis757","article-title":"Serological response to treatment of syphilis according to disease stage and HIV status","volume":"55","author":"Knaute","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0270","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/OLQ.0b013e3181e9afc7","article-title":"Reinfections during the Florida syphilis epidemic, 2000-2008","volume":"38","author":"Brewer","year":"2011","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ad.2019.03.014_bib0275","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1159\/000369617","article-title":"Clinical aspects of syphilis reinfection in HIV-infected patients","volume":"230","author":"Courjon","year":"2015","journal-title":"Dermatology"},{"key":"10.1016\/j.ad.2019.03.014_bib0280","doi-asserted-by":"crossref","first-page":"20948","DOI":"10.2807\/1560-7917.ES2014.19.45.20958","article-title":"Syphilis reinfections pose problems for syphilis diagnosis in Antwerp Belgium \u20141992 to 2012","volume":"19","author":"Kenyon","year":"2014","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ad.2019.03.014_bib0285","doi-asserted-by":"crossref","first-page":"5605","DOI":"10.1128\/IAI.71.10.5605-5612.2003","article-title":"Protection against syphilis correlates with specificity of antibodies to the variable regions of Treponema pallidum repeat protein K","volume":"71","author":"Morgan","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.ad.2019.03.014_bib0290","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00005792-195602000-00002","article-title":"Inoculation syphilis in human volunteers","volume":"35","author":"Magnuson","year":"1956","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ad.2019.03.014_bib0295","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.7326\/0003-4819-114-12-1005","article-title":"Serologic response of treatment of infectius syphilis","volume":"114","author":"Romanowski","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ad.2019.03.014_bib0300","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/S0140-6736(16)32411-4","article-title":"Syphilis","volume":"389","author":"Hook","year":"2017","journal-title":"The Lancet"}],"container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000173101930225X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000173101930225X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T09:31:21Z","timestamp":1762075881000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000173101930225X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["S000173101930225X"],"URL":"https:\/\/doi.org\/10.1016\/j.ad.2019.03.014","relation":{},"ISSN":["0001-7310"],"issn-type":[{"value":"0001-7310","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Las caracter\u00edsticas epidemiol\u00f3gicas y cl\u00ednicas de la epidemia de s\u00edfilis en Barcelona","name":"articletitle","label":"Article Title"},{"value":"Actas Dermo-Sifiliogr\u00e1ficas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ad.2019.03.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 AEDV. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}