{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T12:19:29Z","timestamp":1764937169637,"version":"3.44.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.ad.2019.09.003","type":"journal-article","created":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T00:55:03Z","timestamp":1586393703000},"page":"306-312","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Enfermedad de Paget extramamaria"],"prefix":"10.1016","volume":"111","author":[{"given":"J.","family":"Marcoval","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.M.","family":"Pen\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Bermejo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ad.2019.09.003_bib0170","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1136\/jcp.53.10.742","article-title":"Mammary and extramammary Paget's disease","volume":"53","author":"Lloyd","year":"2000","journal-title":"J Clin Pathol."},{"key":"10.1016\/j.ad.2019.09.003_bib0175","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/14737140.2018.1457955","article-title":"The diagnosis and management of extramammary Paget's disease","volume":"18","author":"Ito","year":"2018","journal-title":"Expert Rev Anticancer Ther."},{"key":"10.1016\/j.ad.2019.09.003_bib0180","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.ejso.2006.11.028","article-title":"Epidemiology and treatment of extramammary Paget disease in the Netherlands","volume":"33","author":"Siesling","year":"2007","journal-title":"Eur J Surg Oncol."},{"key":"10.1016\/j.ad.2019.09.003_bib0185","unstructured":"Kang Z, Zhang Q, Zhang Q, Li X, Hu T, Xu X, et al. Clinical and pathological characteristics of extramammary Paget's disease: report of 246 Chinese male patients. Int J Clin Exp Pathol. 2015; 8:13233-40."},{"key":"10.1016\/j.ad.2019.09.003_bib0190","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1245\/s10434-014-4139-y","article-title":"Extramammary Paget's disease in males: survival outcomes in 495 patients","volume":"22","author":"Herrel","year":"2015","journal-title":"Ann Surg Oncol."},{"key":"10.1016\/j.ad.2019.09.003_bib0195","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jdermsci.2016.06.004","article-title":"A proposal for a TNM staging system for extramammary Paget disease: Retrospective analysis of 301 patients with invasive primary tumors","volume":"83","author":"Ohara","year":"2016","journal-title":"J Dermatol Sci."},{"key":"10.1016\/j.ad.2019.09.003_bib0200","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.mayocp.2018.02.024","article-title":"Evidence-based screening recommendations for occult cancers in the setting of newly diagnosed extramammary Paget disease","volume":"93","author":"Schmitt","year":"2018","journal-title":"Mayo Clin Proc."},{"key":"10.1016\/j.ad.2019.09.003_bib0205","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ejso.2011.12.008","article-title":"Invasive extramammary Paget's disease and the risk for secondary tumours in Europe","volume":"38","author":"van der Zwan","year":"2012","journal-title":"Eur J Surg Oncol."},{"key":"10.1016\/j.ad.2019.09.003_bib0210","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/01.dad.0000158291.20440.13","article-title":"Vulva clear cells of Toker: precursors of extramammary Paget's disease","volume":"27","author":"Willman","year":"2005","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.ad.2019.09.003_bib0215","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0190-9622(85)70254-X","article-title":"Extramammary Paget's disease: prognosis and relationship to internal malignancy","volume":"13","author":"Chanda","year":"1985","journal-title":"J Am Acad Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0220","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1111\/j.1464-410X.2007.07188.x","article-title":"Frozen section-guided wide local excision in the treatment of penoscrotal extramammary Paget's disease","volume":"100","author":"Zhu","year":"2007","journal-title":"BJU Int."},{"key":"10.1016\/j.ad.2019.09.003_bib0225","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/1097-0142(196303)16:3<387::AID-CNCR2820160314>3.0.CO;2-0","article-title":"Anogenital (extramammary) Paget's disease. A clinicopathological study","volume":"16","author":"Helvig","year":"1963","journal-title":"Cancer."},{"key":"10.1016\/j.ad.2019.09.003_bib0230","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/BF02587378","article-title":"Extramammary perianal Paget's disease: report of a case","volume":"20","author":"Grow","year":"1977","journal-title":"Dis Colon Rectum."},{"key":"10.1016\/j.ad.2019.09.003_bib0235","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0463.2008.00816.x","article-title":"Prostate-specific antigen-positive extramammary Paget's disease-association with prostate cancer","volume":"116","author":"Hammer","year":"2008","journal-title":"APMIS."},{"key":"10.1016\/j.ad.2019.09.003_bib0240","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1746-1596-7-106","article-title":"Prostate carcinoma metastatic to the skin as an extramammary Paget's disease","volume":"7","author":"Petcu","year":"2012","journal-title":"Diagn Pathol."},{"key":"10.1016\/j.ad.2019.09.003_bib0245","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/bjd.12851","article-title":"Significant male predisposition in extramammary Paget disease: a nationwide population-based study in Taiwan","volume":"171","author":"Cheng","year":"2014","journal-title":"Br J Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0250","unstructured":"Calonge E. Tumours of Skin Appendages. En: Rook's Textbook of Dermatology. Ninth edition. Griffiths C, Barker J, Bleiker T, Chalmers R, CreamerD, eds. 2016. London. Wiley. Chapter 138."},{"key":"10.1016\/j.ad.2019.09.003_bib0255","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ejogrb.2009.11.003","article-title":"Paget disease of the vulva: a study of 56 cases","volume":"149","author":"Shaco-Levy","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol."},{"key":"10.1016\/j.ad.2019.09.003_bib0260","first-page":"313","article-title":"Extramammary Paget's disease: treatment, prognostic factors and outcome in 76 patients","volume":"158","author":"Hatta","year":"2008","journal-title":"Br J Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0265","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ad.2014.05.008","article-title":"Extramammary Paget disease: a report of 10 cases","volume":"106","author":"Blasco-Morente","year":"2015","journal-title":"Actas Dermosifiliogr."},{"key":"10.1016\/j.ad.2019.09.003_bib0270","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s11864-018-0567-4","article-title":"Prognostic Factors of Extramammary Paget's Disease","volume":"19","author":"Hatta","year":"2018","journal-title":"Curr Treat Options Oncol."},{"key":"10.1016\/j.ad.2019.09.003_bib0275","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.jaad.2017.12.040","article-title":"Evaluation of mapping biopsies for extramammary Paget disease: A retrospective study","volume":"78","author":"Kaku-Ito","year":"2018","journal-title":"J Am Acad Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0280","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1097\/00042728-200307000-00009","article-title":"Comparison of Mohs micrographic surgery and wide excision for extramammary Paget's disease","volume":"29","author":"O\u2019Connor","year":"2003","journal-title":"Dermatol Surg."},{"key":"10.1016\/j.ad.2019.09.003_bib0285","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jaad.2004.07.004","article-title":"Extramammary Paget's disease: surgical treatment with Mohs micrographic surgery","volume":"51","author":"Hendi","year":"2004","journal-title":"J Am Acad Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0290","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/DSS.0000000000001355","article-title":"Intraoperative Immunostaining for Cytokeratin-7 During Mohs Micrographic Surgery Demonstrates Low Local Recurrence Rates in Extramammary Paget's Disease","volume":"44","author":"Damavandy","year":"2018","journal-title":"Dermatol Surg."},{"key":"10.1016\/j.ad.2019.09.003_bib0295","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ygyno.2006.09.017","article-title":"The outcomes of patients with positive margins after excision for intraepithelial Paget's disease of the vulva","volume":"104","author":"Black","year":"2007","journal-title":"Gynecol Oncol."},{"key":"10.1016\/j.ad.2019.09.003_bib0300","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1097\/IGC.0000000000001237","article-title":"The Role of Radiotherapy in Extramammary Paget Disease: A Systematic Review","volume":"28","author":"Tagliaferri","year":"2018","journal-title":"Int J Gynecol Cancer."},{"key":"10.1016\/j.ad.2019.09.003_bib0305","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1684\/ejd.2018.3289","article-title":"Efficacy and tolerance of photodynamic therapy for vulvar Paget's disease: a multicentric retrospective study","volume":"28","author":"Rioli","year":"2018","journal-title":"Eur J Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0310","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1684\/ejd.2015.2534","article-title":"Usefulness of sentinel lymph node biopsy for the detection of metastasis in the early stage of extramammary Paget's disease","volume":"25","author":"Kusatake","year":"2015","journal-title":"Eur J Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0315","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jdermsci.2015.03.014","article-title":"The role of sentinel lymph node biopsy in the management of invasive extramammary Paget's disease: Multi-center, retrospective study of 151 patients","volume":"79","author":"Fujisawa","year":"2015","journal-title":"J Dermatol Sci."},{"key":"10.1016\/j.ad.2019.09.003_bib0320","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1684\/ejd.2016.2744","article-title":"Usefulness of sentinel lymph node biopsy for prognostic prediction in extramammary Paget's disease","volume":"26","author":"Ogata","year":"2016","journal-title":"Eur J Dermatol."},{"key":"10.1016\/j.ad.2019.09.003_bib0325","doi-asserted-by":"crossref","first-page":"6804","DOI":"10.4081\/rt.2016.6804","article-title":"May Clinic Cancer Center Experience of Metastatic Extramammary Paget Disease 1998-2012","volume":"8","author":"Padrnos","year":"2016","journal-title":"Rare Tumors."},{"key":"10.1016\/j.ad.2019.09.003_bib0330","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.juro.2011.02.2685","article-title":"Penoscrotal extramammary Paget's disease: the University of Texas M D. Anderson Cancer Center contemporary experience","volume":"186","author":"Hegarty","year":"2011","journal-title":"J Urol."}],"container-title":["Actas Dermo-Sifiliogr\u00e1ficas"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731020300053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001731020300053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T01:10:06Z","timestamp":1757553006000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001731020300053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0001731020300053"],"URL":"https:\/\/doi.org\/10.1016\/j.ad.2019.09.003","relation":{},"ISSN":["0001-7310"],"issn-type":[{"type":"print","value":"0001-7310"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enfermedad de Paget extramamaria","name":"articletitle","label":"Article Title"},{"value":"Actas Dermo-Sifiliogr\u00e1ficas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ad.2019.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Espa\u00f1a, S.L.U. on behalf of AEDV.","name":"copyright","label":"Copyright"}]}}