{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:15:21Z","timestamp":1785521721116,"version":"3.56.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100004368","name":"Colgate-Palmolive Company","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004368","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.jp","jada.ada.org","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of the American Dental Association"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.adaj.2019.01.006","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T13:18:29Z","timestamp":1550668709000},"page":"S47-S59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"S","title":["Effect of a stannous fluoride toothpaste on dentinal hypersensitivity"],"prefix":"10.1016","volume":"150","author":[{"given":"Deon","family":"Hines","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyou","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Stranick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Lavender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shira","family":"Pilch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Po","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Montesani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Montesani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis R.","family":"Mateo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.adaj.2019.01.006_bib1","first-page":"366","article-title":"Dentin sensitivity and aspiration of odontoblasts","volume":"66","author":"Brannstrom","year":"1963","journal-title":"JADA"},{"key":"10.1016\/j.adaj.2019.01.006_bib2","series-title":"Hypersensitive Dentine: Origin and Management","first-page":"1","article-title":"Mechanism of pain induction in hypersensitive teeth","author":"Trowbridge","year":"1985"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib3","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.archoralbio.2006.09.009","article-title":"Sensory transduction mechanisms responsible for pain caused by cold stimulation of dentine in man","volume":"52","author":"Chidchuangchai","year":"2007","journal-title":"Arch Oral Biol"},{"issue":"11","key":"10.1016\/j.adaj.2019.01.006_bib4","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/j.1600-051X.1997.tb01194.x","article-title":"Guidelines for the design and the conduct of clinical trials on dentine hypersensitivity","volume":"24","author":"Holland","year":"1997","journal-title":"J\u00a0Clin Periodontol"},{"key":"10.1016\/j.adaj.2019.01.006_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1601-1546.2006.00209.x","article-title":"Advances in the treatment of root dentin sensitivity: mechanisms and treatment principles","volume":"13","author":"Gillam","year":"2006","journal-title":"Endod Topics"},{"issue":"special number 2","key":"10.1016\/j.adaj.2019.01.006_bib6","first-page":"10","article-title":"Innovations for combating dentin hypersensitivity: current state of the art","volume":"33","author":"Li","year":"2012","journal-title":"Compend Contin Educ Dent"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib7","first-page":"146","article-title":"Comparative efficacy of two treatment regimens combining in-office and at-home programs for dentin hypersensitivity relief: a 24-week clinical study","volume":"25","author":"Hamlin","year":"2012","journal-title":"Am J Dent"},{"issue":"1","key":"10.1016\/j.adaj.2019.01.006_bib8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/j.1365-2842.2012.02342.x","article-title":"A\u00a0cross-sectional study: non-carious cervical lesions, cervical dentine hypersensitivity and related risk factors","volume":"40","author":"Que","year":"2013","journal-title":"J\u00a0Oral Rehabil"},{"issue":"11","key":"10.1016\/j.adaj.2019.01.006_bib9","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1034\/j.1600-051x.2000.027011860.x","article-title":"The prevalence of dentine hypersensitivity in general dental practice in the UK","volume":"27","author":"Rees","year":"2000","journal-title":"J\u00a0Clin Periodontol"},{"issue":"11","key":"10.1016\/j.adaj.2019.01.006_bib10","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1034\/j.1600-051X.2002.291104.x","article-title":"A\u00a0cross-sectional study of dentine hypersensitivity","volume":"29","author":"Rees","year":"2002","journal-title":"J\u00a0Clin Periodontol"},{"issue":"10","key":"10.1016\/j.adaj.2019.01.006_bib11","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.jdent.2013.07.017","article-title":"Prevalence of dentine hypersensitivity and study of associated factors: a European population-based cross-sectional study","volume":"41","author":"West","year":"2013","journal-title":"J\u00a0Dent"},{"key":"10.1016\/j.adaj.2019.01.006_bib12","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/j.1875-595X.2002.tb00936.x","article-title":"Dentine hypersensitivity: new perspectives on an old problem","volume":"52","author":"Addy","year":"2002","journal-title":"Int Dent J"},{"key":"10.1016\/j.adaj.2019.01.006_bib13","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000350477","article-title":"The role of toothpaste in the aetiology and treatment of dentine hypersensitivity","volume":"23","author":"Addy","year":"2013","journal-title":"Monogr Oral Sci"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/0972-0707.181940","article-title":"Evaluation of dentinal tubule occlusion and depth of penetration of nano-hydroxyapatite derived from chicken eggshell powder with and without addition of sodium fluoride: an in\u00a0vitro study","volume":"19","author":"Kunam","year":"2016","journal-title":"J\u00a0Conserv Dent"},{"issue":"6","key":"10.1016\/j.adaj.2019.01.006_bib15","doi-asserted-by":"crossref","first-page":"269","DOI":"10.5051\/jpis.2013.43.6.269","article-title":"Comparative evaluation of NovaMin desensitizer and Gluma desensitizer on dentinal tubule occlusion: a scanning electron microscopic study","volume":"43","author":"Joshi","year":"2013","journal-title":"J\u00a0Periodontal Implant Sci"},{"issue":"1","key":"10.1016\/j.adaj.2019.01.006_bib16","first-page":"1","article-title":"Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment","volume":"2","author":"Jacobsen","year":"2001","journal-title":"J\u00a0Contemp Dent Pract"},{"issue":"4","key":"10.1016\/j.adaj.2019.01.006_bib17","first-page":"100","article-title":"Advances in the clinical management of dentin hypersensitivity: a review of recent evidence for the efficacy of dentifrices in providing instant and lasting relief","volume":"22","author":"Cummins","year":"2011","journal-title":"J\u00a0Clin Dent"},{"issue":"7","key":"10.1016\/j.adaj.2019.01.006_bib18","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/0003-9969(93)90122-3","article-title":"The effects of outward forced convective flow on inward diffusion in human dentine in\u00a0vitro","volume":"38","author":"Pashley","year":"1993","journal-title":"Arch Oral Biol"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib19","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1177\/10454411960070020101","article-title":"Dynamics of the pulpo-dentinal complex","volume":"7","author":"Pashley","year":"1996","journal-title":"Crit Rev Oral Biol Med"},{"issue":"1","key":"10.1016\/j.adaj.2019.01.006_bib20","first-page":"7","article-title":"Prevalence of dentine hypersensitivity in a general dental population","volume":"43","author":"Irwin","year":"1997","journal-title":"J\u00a0Ir Dent Assoc"},{"issue":"suppl 1","key":"10.1016\/j.adaj.2019.01.006_bib21","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jdent.2012.09.007","article-title":"A\u00a0new treatment alternative for sensitive teeth: a desensitizing oral rinse","volume":"41","author":"Markowitz","year":"2013","journal-title":"J\u00a0Dent"},{"issue":"suppl 1","key":"10.1016\/j.adaj.2019.01.006_bib22","first-page":"39","article-title":"The role of selected cations in the desensitization of intradental nerves","volume":"88","author":"Markowitz","year":"1992","journal-title":"Proc Finn Dent Soc"},{"issue":"7","key":"10.1016\/j.adaj.2019.01.006_bib23","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.archoralbio.2006.12.015","article-title":"Effects of potassium ions on dentine sensitivity in man","volume":"52","author":"Ajcharanukul","year":"2007","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10.1016\/j.adaj.2019.01.006_bib24","first-page":"9","article-title":"The efficacy of potassium salts as agents for treating dentin hypersensitivity","volume":"14","author":"Orchardson","year":"2000","journal-title":"J\u00a0Orofac Pain"},{"key":"10.1016\/j.adaj.2019.01.006_bib25","first-page":"CD001476","article-title":"Potassium containing toothpastes for dentine hypersensitivity","volume":"3","author":"Poulsen","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"special issue A","key":"10.1016\/j.adaj.2019.01.006_bib26","first-page":"3A","article-title":"Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate","volume":"22","author":"Panagakos","year":"2009","journal-title":"Am J Dent"},{"issue":"special issue A","key":"10.1016\/j.adaj.2019.01.006_bib27","first-page":"14A","article-title":"Mode of action studies of a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride","volume":"23","author":"Lavender","year":"2010","journal-title":"Am J Dent"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib28","first-page":"49","volume":"21","author":"Hughes","year":"2010","journal-title":"J\u00a0Clin Dent"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib29","first-page":"66","article-title":"NovaMin and dentin hypersensitivity: in\u00a0vitro evidence of efficacy","volume":"21","author":"Burwell","year":"2010","journal-title":"J\u00a0Clin Dent"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib30","first-page":"71","article-title":"A\u00a0clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity: proof of principle","volume":"21","author":"Litkowski","year":"2010","journal-title":"J\u00a0Clin Dent"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib31","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jdent.2012.11.007","article-title":"A\u00a03-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity","volume":"41","author":"West","year":"2013","journal-title":"J\u00a0Dent"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib32","first-page":"42","volume":"21","author":"Mason","year":"2010","journal-title":"J\u00a0Clin Dent"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib33","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/0022034510388516","article-title":"The short-term effects of diammine silver fluoride on tooth sensitivity: a randomized controlled trial","volume":"90","author":"Castillo","year":"2011","journal-title":"J\u00a0Dent Res"},{"issue":"1 suppl","key":"10.1016\/j.adaj.2019.01.006_bib34","first-page":"27","article-title":"Treating hypersensitivity with fluoride varnishes","volume":"20","author":"Gaffar","year":"1999","journal-title":"Compend Contin Educ Dent"},{"issue":"4","key":"10.1016\/j.adaj.2019.01.006_bib35","first-page":"330","article-title":"Effectiveness of potassium oxalate treatment on dentin hypersensitivity","volume":"37","author":"Cooley","year":"1989","journal-title":"Gen Dent"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib36","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.0305-182X.2003.01230.x","article-title":"Clinical evaluation of ferric oxalate in relieving dentine hypersensitivity","volume":"31","author":"Gillam","year":"2004","journal-title":"J\u00a0Oral Rehabil"},{"issue":"special issue A","key":"10.1016\/j.adaj.2019.01.006_bib37","first-page":"6A","article-title":"Anti-hypersensitivity mechanism of action for a dentifrice containing 0.3% triclosan, 2.0% PVM\/MA copolymer, 0.243% NaF and specially-designed silica","volume":"24","author":"Zaidel","year":"2011","journal-title":"Am J Dent"},{"issue":"Special Issue A","key":"10.1016\/j.adaj.2019.01.006_bib38","first-page":"14","volume":"24","author":"Chaknis","year":"2011","journal-title":"Am J Dent"},{"key":"10.1016\/j.adaj.2019.01.006_bib39","series-title":"Tooth Wear and Sensitivity: Clinical Advances in Restorative Dentistry","first-page":"329","article-title":"Studies with the next generation of home care products for dentine hypersensitivity","author":"Williams","year":"2000"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib40","first-page":"195","article-title":"Clinical effectiveness of dentin sealer in treating dental root sensitivity following periodontal surgery","volume":"42","author":"Vaitkeviciene","year":"2006","journal-title":"Medicina (Kaunas)"},{"issue":"4","key":"10.1016\/j.adaj.2019.01.006_bib41","doi-asserted-by":"crossref","first-page":"218","DOI":"10.4103\/0972-0707.73385","article-title":"Dentin hypersensitivity: recent trends in management","volume":"13","author":"Miglani","year":"2010","journal-title":"J\u00a0Conserv Dent"},{"issue":"2","key":"10.1016\/j.adaj.2019.01.006_bib42","first-page":"55","article-title":"Stannous fluoride\/sodium hexametaphosphate dentifrice increases dentin resistance to tubule exposure in\u00a0vitro","volume":"18","author":"White","year":"2007","journal-title":"J\u00a0Clin Dent"},{"issue":"9 suppl 1","key":"10.1016\/j.adaj.2019.01.006_bib43","first-page":"4","article-title":"A\u00a0novel dentifrice technology for advanced oral health protection: a review of technical and clinical data","volume":"26","author":"Baig","year":"2005","journal-title":"Compend Contin Educ Dent"},{"issue":"7","key":"10.1016\/j.adaj.2019.01.006_bib44","first-page":"990","article-title":"Managing dentin hypersensitivity","volume":"137","author":"Orchardson","year":"2006","journal-title":"JADA"},{"issue":"4S","key":"10.1016\/j.adaj.2019.01.006_bib45","first-page":"S25","article-title":"Effect of stannous fluoride and zinc phosphate dentifrice on dental plaque and gingivitis: a randomized clinical trial with 6-month follow-up","volume":"150","author":"Seriwatanachai","year":"2019","journal-title":"JADA"},{"issue":"4S","key":"10.1016\/j.adaj.2019.01.006_bib46","first-page":"S32","article-title":"Evaluation of a stabilized stannous fluoride dentifrice on dental plaque and gingivitis in a randomized controlled trial with 6-month follow-up","volume":"150","author":"Hu","year":"2019","journal-title":"JADA"},{"issue":"4S","key":"10.1016\/j.adaj.2019.01.006_bib47","first-page":"S38","article-title":"Solving the problem with stannous fluoride: extrinsic stain","volume":"150","author":"Li","year":"2019","journal-title":"JADA"},{"key":"10.1016\/j.adaj.2019.01.006_bib48","author":"Sullivan"},{"issue":"9 suppl","key":"10.1016\/j.adaj.2019.01.006_bib49","first-page":"34","article-title":"Clinical effectiveness of a triclosan\/copolymer\/sodium fluoride dentifrice in controlling oral malodor: a three-week clinical trial","volume":"24","author":"Hu","year":"2003","journal-title":"Compend Contin Educ Dent"},{"issue":"special issue 1","key":"10.1016\/j.adaj.2019.01.006_bib50","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1601-0825.2005.01091.x","article-title":"Clinical effectiveness of a triclosan\/copolymer\/sodium fluoride dentifrice in controlling oral malodor: a 3-week clinical trial","volume":"11","author":"Hu","year":"2005","journal-title":"Oral Dis"},{"issue":"special issue","key":"10.1016\/j.adaj.2019.01.006_bib51","first-page":"106","article-title":"A\u00a0clinical investigation of the efficacy of two dentifrices for controlling oral malodor and plaque microflora overnight","volume":"19","author":"Hu","year":"2008","journal-title":"J\u00a0Clin Dent"},{"issue":"3","key":"10.1016\/j.adaj.2019.01.006_bib52","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0011-8532(22)01133-8","article-title":"Designing hypersensitivity studies","volume":"34","author":"Clark","year":"1990","journal-title":"Dent Clin North Am"},{"issue":"11","key":"10.1016\/j.adaj.2019.01.006_bib53","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.1600-051X.1996.tb00526.x","article-title":"Efficacy of a potassium nitrate mouthwash in alleviating cervical dentine","volume":"23","author":"Gillam","year":"1996","journal-title":"J\u00a0Clin Periodontol"},{"issue":"special number","key":"10.1016\/j.adaj.2019.01.006_bib54","first-page":"87","article-title":"Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM\/MA copolymer, and sodium fluoride on dentinal hypersensitivity: a twelve-week clinical study","volume":"5","author":"Schiff","year":"1994","journal-title":"J\u00a0Clin Dent"}],"container-title":["The Journal of the American Dental Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000281771930008X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000281771930008X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T04:53:42Z","timestamp":1662958422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000281771930008X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":54,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S000281771930008X"],"URL":"https:\/\/doi.org\/10.1016\/j.adaj.2019.01.006","relation":{},"ISSN":["0002-8177"],"issn-type":[{"value":"0002-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of a stannous fluoride toothpaste on dentinal hypersensitivity","name":"articletitle","label":"Article Title"},{"value":"The Journal of the American Dental Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adaj.2019.01.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Dental Association. All rights reserved.","name":"copyright","label":"Copyright"}]}}