{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T23:13:48Z","timestamp":1783811628980,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jada.ada.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of the American Dental Association"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.adaj.2024.12.010","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T14:35:11Z","timestamp":1738334111000},"page":"234-238","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of periodontal disease and the prevalence of acute periapical abscesses"],"prefix":"10.1016","volume":"156","author":[{"given":"Ilan","family":"Rotstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0741-8149","authenticated-orcid":false,"given":"Joseph","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib1","first-page":"6","article-title":"Hospital emergency department visits attributed to pulpal and periapical disease in the United States in 2006","volume":"37","author":"Nalliah","year":"2011","journal-title":"J\u00a0Endod"},{"issue":"9","key":"10.1016\/j.adaj.2024.12.010_bib2","first-page":"1104","article-title":"Outcomes of hospitalizations attributed to periapical abscess from 2000 to 2008: a longitudinal trend analysis","volume":"39","author":"Shah","year":"2013","journal-title":"J\u00a0Endod"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/prd.12188","article-title":"Interaction between endodontics and periodontics","volume":"74","author":"Rotstein","year":"2000","journal-title":"Periodontol"},{"key":"10.1016\/j.adaj.2024.12.010_bib4","series-title":"Ingle\u2019s Endodontics","first-page":"1111","article-title":"Endodontic-periodontal interrelationships","author":"Rotstein","year":"2019"},{"issue":"4","key":"10.1016\/j.adaj.2024.12.010_bib5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1177\/2050168420963305","article-title":"Perio-endo lesions: a guide to diagnosis and clinical management","volume":"9","author":"Sonde","year":"2020","journal-title":"Prim Dent J"},{"issue":"8","key":"10.1016\/j.adaj.2024.12.010_bib6","first-page":"493","article-title":"Ultrastructural observations on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth","volume":"59","author":"Adriaens","year":"1988","journal-title":"J\u00a0Periodontol"},{"issue":"4","key":"10.1016\/j.adaj.2024.12.010_bib7","first-page":"222","article-title":"Bacterial invasion in root cementum and radicular dentin of periodontally diseased teeth in humans: a reservoir of periodontopathic bacteria","volume":"59","author":"Adriaens","year":"1988","journal-title":"J\u00a0Periodontol"},{"issue":"2","key":"10.1016\/j.adaj.2024.12.010_bib8","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0030-4220(74)90421-6","article-title":"Periodontal disease, bacteria, and pulpal histopathology","volume":"37","author":"Langeland","year":"1974","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"8","key":"10.1016\/j.adaj.2024.12.010_bib9","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1034\/j.1600-051X.2002.290801.x","article-title":"Pathologic interactions in pulpal and periodontal tissues","volume":"29","author":"Zehnder","year":"2002","journal-title":"J\u00a0Clin Periodontol"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib10","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/0973-029X.203795","article-title":"Pulpal changes associated with advanced periodontal disease: a histopathological study","volume":"21","author":"Gautam","year":"2017","journal-title":"J\u00a0Oral Maxillofac Pathol"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib11","doi-asserted-by":"crossref","first-page":"10","DOI":"10.34172\/japid.2023.005","article-title":"Histological characteristics of dental pulp in teeth with periodontal problems and healthy teeth","volume":"15","author":"Vaziri","year":"2022","journal-title":"J\u00a0Adv Periodontol Implant Dent"},{"issue":"4","key":"10.1016\/j.adaj.2024.12.010_bib12","first-page":"169","article-title":"Bacteria invading periapical cementum","volume":"20","author":"Kiryu","year":"1994","journal-title":"J\u00a0Endod"},{"issue":"5","key":"10.1016\/j.adaj.2024.12.010_bib13","first-page":"740","article-title":"Pulp response to periodontal disease: novel observations help clarify the processes of tissue breakdown and infection","volume":"47","author":"Ricucci","year":"2021","journal-title":"J\u00a0Endod"},{"key":"10.1016\/j.adaj.2024.12.010_bib14","series-title":"Handbook of Parametric and Nonparametric Statistical Procedures","first-page":"761","author":"Sheskin","year":"2011"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib15","article-title":"Assessment of pulp vitality in multirooted teeth with advanced periodontal disease: a clinical and histological study","volume":"15","author":"Arulmari","year":"2023","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.adaj.2024.12.010_bib16","first-page":"635","article-title":"Pulp status of teeth in patients with chronic advanced periodontitis","volume":"13","author":"Tan","year":"2020","journal-title":"Int J Clin Exp Pathol"},{"issue":"2","key":"10.1016\/j.adaj.2024.12.010_bib17","first-page":"164","article-title":"Histopathological investigation of dental pulp reactions related to periodontitis","volume":"6","author":"Sabeti","year":"2021","journal-title":"Eur Endod J"},{"issue":"11","key":"10.1016\/j.adaj.2024.12.010_bib18","first-page":"361","article-title":"Frequency, location and direction of the lateral, secondary and accessory canals","volume":"1","author":"De Deus","year":"1975","journal-title":"J\u00a0Endod"},{"issue":"4","key":"10.1016\/j.adaj.2024.12.010_bib19","first-page":"176","article-title":"Accessory orifices: anatomical relationship between the pulp chamber floor and the furcation","volume":"13","author":"Goldberg","year":"1987","journal-title":"J\u00a0Endod"},{"issue":"6","key":"10.1016\/j.adaj.2024.12.010_bib20","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1111\/iej.12030","article-title":"Cytokines as diagnostic markers of pulpal inflammation","volume":"46","author":"Elsalhy","year":"2013","journal-title":"Int Endod J"},{"issue":"9","key":"10.1016\/j.adaj.2024.12.010_bib21","first-page":"1090","article-title":"Evaluation of serum levels of cytokines in acute apical abscess: a longitudinal observational study","volume":"49","author":"Palafox-S\u00e1nchez","year":"2023","journal-title":"J\u00a0Endod"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib22","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/prd.12318","article-title":"The impact of diabetes on periodontal diseases","volume":"82","author":"Graves","year":"2020","journal-title":"Periodontol 2000"},{"issue":"11","key":"10.1016\/j.adaj.2024.12.010_bib23","first-page":"1605","article-title":"Diabetes mellitus and periapical abscess: a cross-sectional study","volume":"46","author":"Saleh","year":"2020","journal-title":"J\u00a0Endod"},{"issue":"6","key":"10.1016\/j.adaj.2024.12.010_bib24","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00784-016-1805-4","article-title":"Association between diabetes and the prevalence of radiolucent periapical lesions in root-filled teeth: systematic review and meta-analysis","volume":"20","author":"Segura-Egea","year":"2016","journal-title":"Clin Oral Investig"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib25","first-page":"43","article-title":"The effect of diabetes mellitus on endodontic treatment outcome: data from an electronic patient record","volume":"134","author":"Fouad","year":"2003","journal-title":"JADA"},{"issue":"1","key":"10.1016\/j.adaj.2024.12.010_bib26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/prd.12449","article-title":"The role of cigarette smoking in periodontal disease and treatment outcomes of dental implant therapy","volume":"90","author":"Apatzidou","year":"2022","journal-title":"Periodontol 2000"},{"issue":"10","key":"10.1016\/j.adaj.2024.12.010_bib27","first-page":"1445","article-title":"Smoking and bone. Article in Japanese","volume":"26","author":"Watanabe","year":"2016","journal-title":"Clin Calcium"},{"issue":"2","key":"10.1016\/j.adaj.2024.12.010_bib28","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/jcpe.14087","article-title":"Hypoxic responses in periodontal tissues: influence of smoking and periodontitis","volume":"52","author":"Bozyel","year":"2025","journal-title":"J\u00a0Clin Periodontol"},{"issue":"8","key":"10.1016\/j.adaj.2024.12.010_bib29","first-page":"487","article-title":"Prevalence of periapical pathosis in smokers versus nonsmokers: a cross-sectional study","volume":"49","author":"Rotstein","year":"2021","journal-title":"J\u00a0Calif Dent Assoc"}],"container-title":["The Journal of the American Dental Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817725000388?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817725000388?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T20:57:27Z","timestamp":1742331447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002817725000388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0002817725000388"],"URL":"https:\/\/doi.org\/10.1016\/j.adaj.2024.12.010","relation":{},"ISSN":["0002-8177"],"issn-type":[{"value":"0002-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of periodontal disease and the prevalence of acute periapical abscesses","name":"articletitle","label":"Article Title"},{"value":"The Journal of the American Dental Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adaj.2024.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Dental Association. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}