{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:36:07Z","timestamp":1777955767761,"version":"3.51.4"},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","jada.ada.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of the American Dental Association"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.adaj.2025.10.006","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T17:57:24Z","timestamp":1763229444000},"page":"285-293","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare manifestation of dental implant failure associated with sarcoidosis"],"prefix":"10.1016","volume":"157","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6634-8470","authenticated-orcid":false,"given":"John K.","family":"Brooks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9822-0196","authenticated-orcid":false,"given":"Arash","family":"Rostami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura H.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8477-4067","authenticated-orcid":false,"given":"Azin","family":"Parsa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim L.","family":"Spivak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindy Q.","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5286-4562","authenticated-orcid":false,"given":"Ahmed S.","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.adaj.2025.10.006_bib1","article-title":"Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study","volume":"12","author":"Cao","year":"2025","journal-title":"Front Med (Lausanne)"},{"issue":"11","key":"10.1016\/j.adaj.2025.10.006_bib2","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1902\/jop.2007.070117","article-title":"Sarcoidosis affecting the periodontium: a long-term follow-up case","volume":"78","author":"Moretti","year":"2007","journal-title":"J Periodontol"},{"issue":"8","key":"10.1016\/j.adaj.2025.10.006_bib3","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/qjmed\/hcs042","article-title":"Oral involvement in sarcoidosis: report of 12 cases","volume":"105","author":"Bouaziz","year":"2012","journal-title":"QJM"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib4","article-title":"Primary sarcoidosis of the temporal bone a clinical pathologic correlation","volume":"3","author":"Fallon","year":"2023","journal-title":"Otol Neurotol Open"},{"issue":"12","key":"10.1016\/j.adaj.2025.10.006_bib5","doi-asserted-by":"crossref","first-page":"5744","DOI":"10.1016\/j.radcr.2024.08.115","article-title":"Symptomatic hypercalcemia and lytic lesions of the skull revealing sarcoidosis: a case report","volume":"19","author":"Tounsi","year":"2024","journal-title":"Radiol Case Rep"},{"key":"10.1016\/j.adaj.2025.10.006_bib6","article-title":"Phalange osteolysis present as the initial manifestation of sarcoidosis in a young female","volume":"13","author":"Zhang","year":"2025","journal-title":"SAGE Open Med Case Rep"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib7","article-title":"Sarcoidosis: key disease aspects and update on management","volume":"25","author":"Coker","year":"2025","journal-title":"Clin Med (Lond)"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib8","article-title":"Osseous sarcoidosis: three typical presentations of an atypical disease","volume":"17","author":"Ray","year":"2025","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.adaj.2025.10.006_bib9","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.joms.2021.11.017","article-title":"A rare presentation of intraosseous sarcoidosis of the mandible presenting as peri-implantitis: a case report and literature review","volume":"80","author":"Cheema","year":"2022","journal-title":"J Oral Maxillofac Surg"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.12968\/denu.2003.30.5.264","article-title":"Sarcoidosis of the gingiva: a case report","volume":"30","author":"Ho","year":"2003","journal-title":"Dent Update"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib11","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1902\/jop.2004.75.3.478","article-title":"Intraosseous sarcoidosis of the jaws mimicking aggressive periodontitis: a case report and literature review","volume":"75","author":"Suresh","year":"2004","journal-title":"J Periodontol"},{"issue":"6","key":"10.1016\/j.adaj.2025.10.006_bib12","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.joms.2005.09.028","article-title":"Oral sarcoidosis: report of a case and review of literature","volume":"65","author":"Kasamatsu","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"issue":"11","key":"10.1016\/j.adaj.2025.10.006_bib13","first-page":"ZD25","article-title":"Sarcoidosis presenting as isolated gingival enlargement: a rare case entity","volume":"8","author":"Tripathi","year":"2014","journal-title":"J Clin Diagn Res"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib14","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1563\/aaid-joi-D-18-00309","article-title":"Prosthetic rehabilitation of a patient diagnosed with sarcoidosis using dental implants: a clinical case report","volume":"46","author":"James","year":"2020","journal-title":"J Oral Implantol"},{"issue":"4","key":"10.1016\/j.adaj.2025.10.006_bib15","doi-asserted-by":"crossref","first-page":"e280","DOI":"10.1016\/j.oooo.2013.06.016","article-title":"A rare clinical presentation of sarcoidosis; gingivitis","volume":"116","author":"G\u00fczel","year":"2013","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.adaj.2025.10.006_bib16","series-title":"Oral and Maxillofacial Pathology","first-page":"328","year":"2024"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib17","doi-asserted-by":"crossref","first-page":"582","DOI":"10.4103\/0972-124X.167167","article-title":"Sarcoidosis: oral and extra-oral manifestation","volume":"19","author":"Gupta","year":"2015","journal-title":"J Indian Soc Periodontol"},{"issue":"4","key":"10.1016\/j.adaj.2025.10.006_bib18","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S1079-2104(97)90145-1","article-title":"Oral manifestations of sarcoidosis","volume":"83","author":"Blinder","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"12","key":"10.1016\/j.adaj.2025.10.006_bib19","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1016\/j.joms.2012.01.014","article-title":"Sarcoidosis presenting as a lytic lesion of the mandible","volume":"70","author":"Cain","year":"2012","journal-title":"J Oral Maxillofac Surg"},{"issue":"11","key":"10.1016\/j.adaj.2025.10.006_bib20","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1902\/jop.1983.54.11.690","article-title":"Rapidly advancing periodontitis in a patient with sarcoidosis: a case report","volume":"54","author":"Makris","year":"1983","journal-title":"J Periodontol"},{"issue":"10","key":"10.1016\/j.adaj.2025.10.006_bib21","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1053\/joms.2000.9577","article-title":"Persistent anterior maxillary bone loss","volume":"58","author":"White","year":"2000","journal-title":"J Oral Maxillofac Surg"},{"issue":"1","key":"10.1016\/j.adaj.2025.10.006_bib22","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1902\/cap.2015.150006","article-title":"Clinical presentation and periodontal management of a case mimicking generalized aggressive periodontitis in a patient with sarcoidosis: a case report","volume":"6","author":"Smitha","year":"2016","journal-title":"Clin Adv Periodontics"},{"issue":"2","key":"10.1016\/j.adaj.2025.10.006_bib23","first-page":"52","article-title":"Sarcoidosis with involvement of the maxilla","volume":"37","author":"Aragon","year":"1982","journal-title":"J Oral Med"},{"issue":"6","key":"10.1016\/j.adaj.2025.10.006_bib24","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.ijom.2003.09.012","article-title":"Mandibular intrabony lesion as first sign of sarcoidosis: case report","volume":"33","author":"Grimaldi","year":"2004","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"1","key":"10.1016\/j.adaj.2025.10.006_bib25","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2020-237105","article-title":"Extensive bony sarcoidosis of the head and neck region: a rare presentation","volume":"14","author":"Hosni","year":"2021","journal-title":"BMJ Case Rep"},{"issue":"12","key":"10.1016\/j.adaj.2025.10.006_bib26","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/0278-2391(91)90318-G","article-title":"Maxillary alveolar bone loss in a patient with sarcoidosis","volume":"49","author":"Rubin","year":"1991","journal-title":"J Oral Maxillofac Surg"},{"issue":"18","key":"10.1016\/j.adaj.2025.10.006_bib27","doi-asserted-by":"crossref","first-page":"E904","DOI":"10.1097\/BRS.0b013e3181dc9a54","article-title":"Osseous sarcoidosis treated with tumor necrosis factor-inhibitors: case report and review of the literature","volume":"35","author":"Hasni","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib28","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/MCP.0000000000001202","article-title":"Deciphering sarcoidosis immunopathogenesis through systems biology","volume":"31","author":"Jbeli","year":"2025","journal-title":"Curr Opin Pulm Med"},{"issue":"6","key":"10.1016\/j.adaj.2025.10.006_bib29","article-title":"Systemic sarcoidosis presenting with hypercalcemia, acute kidney injury, and diffuse lymphadenopathy: unlocking Pandora\u2019s box","volume":"17","author":"Geladari","year":"2025","journal-title":"Cureus"},{"key":"10.1016\/j.adaj.2025.10.006_bib30","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/615486","article-title":"Mechanisms of bone resorption in periodontitis","volume":"2015","author":"Hienz","year":"2015","journal-title":"J Immunol Res"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib31","article-title":"Cheilitis granulomatosa: a case report of a sarcoid mimic","volume":"17","author":"Nagy","year":"2025","journal-title":"Cureus"},{"key":"10.1016\/j.adaj.2025.10.006_bib32","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.3389\/fimmu.2020.01443","article-title":"Biomarkers in the diagnosis and prognosis of sarcoidosis: current use and future prospects","volume":"11","author":"Kraaijvanger","year":"2020","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.adaj.2025.10.006_bib33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3390\/cells11010059","article-title":"Clinical features, histopathology and differential diagnosis of sarcoidosis","volume":"11","author":"Tana","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.adaj.2025.10.006_bib34","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ejim.2022.12.003","article-title":"Role of anti-tumor necrosis factor-alpha agents in treatment of sarcoidosis: a meta-analysis","volume":"109","author":"Rezaee","year":"2023","journal-title":"Eur J Intern Med"},{"issue":"11","key":"10.1016\/j.adaj.2025.10.006_bib35","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1056\/NEJMra2101555","article-title":"Challenges of sarcoidosis and its management","volume":"385","author":"Drent","year":"2021","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.adaj.2025.10.006_bib36","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4103\/0976-237X.123087","article-title":"Gingival enlargement unveiling sarcoidosis: report of a rare case","volume":"4","author":"Kadiwala","year":"2013","journal-title":"Contemp Clin Dent"},{"issue":"6","key":"10.1016\/j.adaj.2025.10.006_bib37","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.joms.2019.01.018","article-title":"Primary oral presentation of sarcoidosis in a pediatric patient","volume":"77","author":"Dammling","year":"2019","journal-title":"J Oral Maxillofac Surg"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib38","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jormas.2020.03.010","article-title":"Multiple nodules of the oral mucosa","volume":"121","author":"Hadj Sa\u00efd","year":"2020","journal-title":"J Stomatol Oral Maxillofac Surg"},{"issue":"9","key":"10.1016\/j.adaj.2025.10.006_bib39","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1111\/clr.14456","article-title":"Implant survival in patient populations with a mean age of 65-75 years compared to older cohorts: a systematic review and meta-analysis","volume":"36","author":"Abou-Ayash","year":"2025","journal-title":"Clin Oral Implants Res"},{"issue":"suppl 20","key":"10.1016\/j.adaj.2025.10.006_bib40","first-page":"S286","article-title":"Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Berglundh","year":"2018","journal-title":"J Clin Periodontol"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib41","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S1079-2104(98)90349-3","article-title":"The effect of periradicular endodontic pathosis on the apical region of adjacent implants","volume":"86","author":"Shaffer","year":"1998","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"3","key":"10.1016\/j.adaj.2025.10.006_bib42","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/jrnms-100-328","article-title":"Vitamin D deficiency as a suspected causative factor in the failure of an immediately placed dental implant: a case report","volume":"100","author":"Bryce","year":"2014","journal-title":"J R Nav Med Serv"},{"issue":"2","key":"10.1016\/j.adaj.2025.10.006_bib43","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ijom.2017.07.012","article-title":"Previously successful dental implants can fail when patients commence anti-resorptive therapy: a case series","volume":"47","author":"Pogrel","year":"2018","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"1","key":"10.1016\/j.adaj.2025.10.006_bib44","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/dj11010010","article-title":"Systemic diseases and biological dental implant complications: a narrative review","volume":"11","author":"Sbricoli","year":"2022","journal-title":"Dent J (Basel)"},{"issue":"2","key":"10.1016\/j.adaj.2025.10.006_bib45","first-page":"65","article-title":"Dental implant failure possibly attributed to embedded pencil graphite: first clinical report","volume":"72","author":"Brooks","year":"2024","journal-title":"Gen Dent"},{"issue":"5","key":"10.1016\/j.adaj.2025.10.006_bib46","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.oooo.2024.06.003","article-title":"Osseointegrated dental implants that will undergo radiotherapy. Does risk of osteoradionecrosis exist? A scoping review","volume":"138","author":"Prado-Pena","year":"2024","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"1","key":"10.1016\/j.adaj.2025.10.006_bib47","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.oooo.2016.08.023","article-title":"Clinicopathologic evaluation of malignancy adjacent to dental implants","volume":"123","author":"Kaplan","year":"2017","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"13","key":"10.1016\/j.adaj.2025.10.006_bib48","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.3390\/cancers17132149","article-title":"Peri-implant oral squamous cell carcinoma (OSCC): clinicopathological features and staging issues","volume":"17","author":"Limongelli","year":"2025","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.adaj.2025.10.006_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2025.105773","article-title":"Peri-implantitis and peri-implant oral malignancies: a systematic review and meta-analysis of diagnostic challenges and potential associations","volume":"160","author":"Srinivasan","year":"2025","journal-title":"J Dent"}],"container-title":["The Journal of the American Dental Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817725006245?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817725006245?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:33:56Z","timestamp":1777937636000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002817725006245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S0002817725006245"],"URL":"https:\/\/doi.org\/10.1016\/j.adaj.2025.10.006","relation":{},"ISSN":["0002-8177"],"issn-type":[{"value":"0002-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A rare manifestation of dental implant failure associated with sarcoidosis","name":"articletitle","label":"Article Title"},{"value":"The Journal of the American Dental Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adaj.2025.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Dental Association.","name":"copyright","label":"Copyright"}]}}