{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:51:05Z","timestamp":1792068665953,"version":"4.4.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:00:00Z","timestamp":1758585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["AA026186"],"award-info":[{"award-number":["AA026186"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Addiction Neuroscience"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.addicn.2025.100237","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:48:56Z","timestamp":1758710936000},"page":"100237","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner"],"prefix":"10.1016","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4413-9920","authenticated-orcid":false,"given":"Sema G","family":"Quadir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Danyal","family":"Zaidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith G","family":"Cone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.addicn.2025.100237_bib0001","unstructured":"NSDUH. 2023 National Survey on Drug Use and Health (NSDUH) 2023 NSDUH section 2: tobacco product use, nicotine vaping, and alcohol use tables - .1 to 2.47; section 5: substance use disorder and treatment Tables - 5.1 to 5.35]."},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0002","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0893-133X(00)00195-0","article-title":"Drug addiction, dysregulation of reward, and allostasis","volume":"24","author":"Koob","year":"2001","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.addicn.2025.100237_bib0003","series-title":"Neurobiology of Addiction","author":"Koob","year":"2005"},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0004","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S2215-0366(16)00104-8","article-title":"Neurobiology of addiction: a neurocircuitry analysis","volume":"3","author":"Koob","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0005","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1001\/jama.2018.11406","article-title":"Diagnosis and pharmacotherapy of alcohol use disorder: a review","volume":"320","author":"Kranzler","year":"2018","journal-title":"Jama"},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0006","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1176\/appi.ajp.158.2.198","article-title":"Evidence for a gender-related effect of alcoholism on brain volumes","volume":"158","author":"Hommer","year":"2001","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.addicn.2025.100237_bib0007","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1097\/01.ALC.0000164376.69978.6B","article-title":"Neuroimaging of gender differences in alcohol dependence: are women more vulnerable?","volume":"29","author":"Mann","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0008","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1124\/pharmrev.121.000361","article-title":"Sex\/gender differences in the time-course for the development of substance use disorder: a focus on the telescoping effect","volume":"75","author":"Towers","year":"2023","journal-title":"Pharmacol. Rev."},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0009","doi-asserted-by":"crossref","first-page":"03","DOI":"10.35946\/arcr.v40.3.03","article-title":"Sex and gender effects in recovery from alcohol use disorder","volume":"40","author":"Holzhauer","year":"2020","journal-title":"Alcohol Res."},{"issue":"11","key":"10.1016\/j.addicn.2025.100237_bib0011","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.biopsych.2022.03.008","article-title":"Mesial prefrontal cortex and alcohol misuse: dissociating cross-sectional and longitudinal relationships in UK Biobank","volume":"92","author":"Zhao","year":"2022","journal-title":"Biol. psychiatry"},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0012","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1001\/archgenpsychiatry.2011.2026","article-title":"Effect of brain structure, brain function, and brain connectivity on relapse in alcohol-dependent patients","volume":"69","author":"Beck","year":"2012","journal-title":"Arch. Gen. Psychiatry"},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0013","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s00213-004-1828-4","article-title":"Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics","volume":"175","author":"Grusser","year":"2004","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.addicn.2025.100237_bib0014","doi-asserted-by":"crossref","unstructured":"Blaine S.K., Wemm S., Fogelman N., Lacadie C., Seo D., Scheinost D., Sinha R. Association of prefrontal-striatal functional pathology with alcohol abstinence days at treatment initiation and heavy drinking after treatment initiation. The American journal of psychiatry. 2020;177(11):1048-59. Epub 20200828. doi: 10.1176\/appi.ajp.2020.19070703. PubMed PMID: 32854534; PMCID: PMC7606814.","DOI":"10.1176\/appi.ajp.2020.19070703"},{"key":"10.1016\/j.addicn.2025.100237_bib0015","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0074-7742(10)91009-X","article-title":"Alcohol and the prefrontal cortex","volume":"91","author":"Abernathy","year":"2010","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.addicn.2025.100237_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fnsyn.2022.936911","article-title":"Targeting prefrontal cortex GABAergic microcircuits for the treatment of alcohol use disorder","volume":"14","author":"Fish","year":"2022","journal-title":"Front. Synaptic. Neurosci."},{"issue":"1","key":"10.1016\/j.addicn.2025.100237_bib0017","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41386-021-01119-x","article-title":"Developing breakthrough psychiatric treatments by modulating G protein-coupled receptors on prefrontal cortex somatostatin interneurons","volume":"47","author":"Crowley","year":"2022","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0018","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/cne.22229","article-title":"Immunochemical characterization of inhibitory mouse cortical neurons: three chemically distinct classes of inhibitory cells","volume":"518","author":"Xu","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.addicn.2025.100237_bib0019","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3389\/fncir.2018.00037","article-title":"PV interneurons: critical regulators of E\/I balance for prefrontal cortex-dependent behavior and psychiatric disorders","volume":"12","author":"Ferguson","year":"2018","journal-title":"Front Neural Circuits"},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0020","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.neuron.2016.06.033","article-title":"GABAergic interneurons in the neocortex: from cellular properties to circuits","volume":"91","author":"Tremblay","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.addicn.2025.100237_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.108126","article-title":"Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking","volume":"178","author":"Joffe","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.addicn.2025.100237_bib0022","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.alcohol.2022.02.003","article-title":"Prefrontal cortex parvalbumin interneurons exhibit decreased excitability and potentiated synaptic strength after ethanol reward learning","volume":"101","author":"Ferranti","year":"2022","journal-title":"Alcohol"},{"issue":"11","key":"10.1016\/j.addicn.2025.100237_bib0023","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1038\/s41386-021-01050-1","article-title":"Somatostatin neurons control an alcohol binge drinking prelimbic microcircuit in mice","volume":"46","author":"Dao","year":"2021","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.addicn.2025.100237_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109638","article-title":"Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons","volume":"238","author":"Thompson","year":"2023","journal-title":"Neuropharmacology"},{"issue":"11","key":"10.1016\/j.addicn.2025.100237_bib0025","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1111\/acer.14949","article-title":"2-Arachidonoylglycerol-mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice","volume":"46","author":"Morgan","year":"2022","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0026","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/s41386-018-0257-8","article-title":"Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence","volume":"44","author":"Centanni","year":"2019","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0027","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1038\/npp.2016.3","article-title":"Ketamine and MAG lipase inhibitor-dependent reversal of evolving depressive-like behavior during forced abstinence from alcohol drinking","volume":"41","author":"Holleran","year":"2016","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"issue":"1","key":"10.1016\/j.addicn.2025.100237_bib0028","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1038\/s41467-017-02365-8","article-title":"Midbrain circuit regulation of individual alcohol drinking behaviors in mice","volume":"8","author":"Juarez","year":"2017","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.addicn.2025.100237_bib0029","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.neuron.2019.12.024","article-title":"Endocannabinoid signaling collapse mediates stress-induced amygdalo-cortical strengthening","volume":"105","author":"Marcus","year":"2020","journal-title":"Neuron"},{"issue":"34","key":"10.1016\/j.addicn.2025.100237_bib0030","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2300585120","article-title":"Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons","volume":"120","author":"Kondev","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"132","key":"10.1016\/j.addicn.2025.100237_bib0031","doi-asserted-by":"crossref","DOI":"10.3791\/53825","article-title":"Preparation of acute brain slices using an optimized N-methyl-D-glucamine protective recovery method","author":"Ting","year":"2018","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.addicn.2025.100237_bib0032","unstructured":"Marino M., Misuri L., Brogioli D. A new open source software for the calculation of the liquid junction potential between two solutions according to the stationary Nernst-Planck equation. arXiv preprint 2014."},{"key":"10.1016\/j.addicn.2025.100237_bib0033","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fninf.2014.00016","article-title":"Stimfit: quantifying electrophysiological data with Python","volume":"8","author":"Guzman","year":"2014","journal-title":"Front. Neuroinform."},{"issue":"12","key":"10.1016\/j.addicn.2025.100237_bib0034","doi-asserted-by":"crossref","first-page":"4854","DOI":"10.1093\/cercor\/bhv202","article-title":"Characterizing VIP neurons in the barrel cortex of VIPcre\/tdTomato Mice reveals layer-specific differences","volume":"25","author":"Pronneke","year":"2015","journal-title":"Cereb. Cortex"},{"issue":"7","key":"10.1016\/j.addicn.2025.100237_bib0035","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.tins.2021.03.006","article-title":"Circuit organization of the rodent medial prefrontal cortex","volume":"44","author":"Anastasiades","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.addicn.2025.100237_bib0036","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3389\/fncir.2016.00035","article-title":"Inhibitory circuits in cortical layer 5","volume":"10","author":"Naka","year":"2016","journal-title":"Front. Neural. Circuits"},{"issue":"1","key":"10.1016\/j.addicn.2025.100237_bib0037","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/dneu.20853","article-title":"Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons","volume":"71","author":"Rudy","year":"2011","journal-title":"Dev. Neurobiol"},{"key":"10.1016\/j.addicn.2025.100237_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109527","article-title":"Alcohol potentiates multiple GABAergic inputs to dorsal striatum fast-spiking interneurons","volume":"232","author":"Patton","year":"2023","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.addicn.2025.100237_bib0039","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.787362","article-title":"Viral-mediated knockdown of nucleus accumbens shell PAC1 receptor promotes excessive alcohol drinking in alcohol-preferring rats","volume":"15","author":"Minnig","year":"2021","journal-title":"Front. Behav. Neurosci."},{"issue":"1","key":"10.1016\/j.addicn.2025.100237_bib0040","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/s41398-024-02821-2","article-title":"Estrogen signaling in the dorsal raphe regulates binge-like drinking in mice","volume":"14","author":"Torres Irizarry","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.addicn.2025.100237_bib0041","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neuroscience.2020.07.024","article-title":"Bidirectional control of alcohol-drinking behaviors through Locus Coeruleus optoactivation","volume":"443","author":"Deal","year":"2020","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0042","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/acer.14546","article-title":"Increased synaptic strength and mGlu(2\/3) receptor plasticity on mouse prefrontal cortex intratelencephalic pyramidal cells following intermittent access to ethanol","volume":"45","author":"Joffe","year":"2021","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"12","key":"10.1016\/j.addicn.2025.100237_bib0043","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1038\/npp.2008.7","article-title":"Escalated aggression after alcohol drinking in male mice: dorsal raphe and prefrontal cortex serotonin and 5-HT(1B) receptors","volume":"33","author":"Faccidomo","year":"2008","journal-title":"Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"key":"10.1016\/j.addicn.2025.100237_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2019.107805","article-title":"Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain","volume":"162","author":"Hughes","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.addicn.2025.100237_bib0045","unstructured":"Thompson S.M., Ferranti A.S., Joffe M.E. Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons. BioRxiv. 2023. Epub 2023\/03\/23. doi: 10.1101\/2023.03.07.531614. PubMed PMID: 36945582; PMCID: PMC10028880 R00AA027806], the Whitehall Foundation [grant number 2022-08-005], and the Brain and Behavior Research Foundation. The authors declare no potential conflicts of interest."},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0046","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1007\/s12031-022-02040-8","article-title":"Cortical VIP(+) interneurons in the upper and deeper layers are transcriptionally distinct","volume":"72","author":"Wu","year":"2022","journal-title":"J. Mol. Neurosci."},{"issue":"4","key":"10.1016\/j.addicn.2025.100237_bib0047","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.cell.2020.09.057","article-title":"Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells","volume":"183","author":"Gouwens","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.addicn.2025.100237_bib0048","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2022.811484","article-title":"VIP-expressing GABAergic neurons: disinhibitory vs. Inhibitory motif and its role in communication across neocortical areas","volume":"16","author":"Apicella","year":"2022","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.addicn.2025.100237_bib0049","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3389\/fncir.2013.00195","article-title":"Not all that glitters is gold: off-target recombination in the somatostatin-IRES-Cre mouse line labels a subset of fast-spiking interneurons","volume":"7","author":"Hu","year":"2013","journal-title":"Front Neural Circuits"},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0050","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/nn.3446","article-title":"Inhibition of inhibition in visual cortex: the logic of connections between molecularly distinct interneurons","volume":"16","author":"Pfeffer","year":"2013","journal-title":"Nat. Neurosci."},{"issue":"10","key":"10.1016\/j.addicn.2025.100237_bib0051","doi-asserted-by":"crossref","first-page":"5001","DOI":"10.1093\/cercor\/bhx203","article-title":"Fast-spiking parvalbumin interneurons are frequently myelinated in the cerebral cortex of mice and humans","volume":"27","author":"Stedehouder","year":"2017","journal-title":"Cereb Cortex"},{"issue":"5","key":"10.1016\/j.addicn.2025.100237_bib0052","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109950","article-title":"mGlu(1) potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits","volume":"37","author":"Maksymetz","year":"2021","journal-title":"Cell Rep"},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0053","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.neuron.2014.09.033","article-title":"Tolias AS. Pupil fluctuations track fast switching of cortical states during quiet wakefulness","volume":"84","author":"Reimer","year":"2014","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0054","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.neuron.2019.07.027","article-title":"Recruitment of GABAergic interneurons in the barrel cortex during active tactile behavior","volume":"104","author":"Yu","year":"2019","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.addicn.2025.100237_bib0055","doi-asserted-by":"crossref","first-page":"4174","DOI":"10.1038\/s41467-019-12058-z","article-title":"Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas","volume":"10","author":"Scala","year":"2019","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.addicn.2025.100237_bib0056","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.neuron.2021.12.027","article-title":"Acute restraint stress redirects prefrontal cortex circuit function through mGlu(5) receptor plasticity on somatostatin-expressing interneurons","volume":"110","author":"Joffe","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.addicn.2025.100237_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108501","article-title":"Alcohol reduces the activity of somatostatin interneurons in the mouse prefrontal cortex: a neural basis for its disinhibitory effect?","volume":"188","author":"Li","year":"2021","journal-title":"Neuropharmacology"},{"issue":"50","key":"10.1016\/j.addicn.2025.100237_bib0058","doi-asserted-by":"crossref","first-page":"16796","DOI":"10.1523\/JNEUROSCI.1869-10.2010","article-title":"The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors","volume":"30","author":"Lee","year":"2010","journal-title":"J. Neurosci.: Off. J. Soc. Neurosci."},{"issue":"8","key":"10.1016\/j.addicn.2025.100237_bib0059","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0204-23.2023","article-title":"Genetically defined subtypes of somatostatin-containing cortical interneurons","volume":"10","author":"Hostetler","year":"2023","journal-title":"eNeuro"},{"issue":"4","key":"10.1016\/j.addicn.2025.100237_bib0060","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0112-16.2016","article-title":"Perineuronal nets enhance the excitability of fast-spiking neurons","volume":"3","author":"Balmer","year":"2016","journal-title":"eNeuro"},{"key":"10.1016\/j.addicn.2025.100237_bib0061","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2024.07.007","article-title":"Emerging pharmacological targets for alcohol use disorder","author":"Brockway","year":"2024","journal-title":"Alcohol"},{"issue":"2","key":"10.1016\/j.addicn.2025.100237_bib0062","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.bpsgos.2022.03.002","article-title":"Medial prefrontal cortex theta burst stimulation improves treatment outcomes in alcohol use disorder: a double-blind, sham-controlled neuroimaging study","volume":"3","author":"McCalley","year":"2023","journal-title":"Biol. Psychiatry Glob. Open Sci."},{"issue":"3","key":"10.1016\/j.addicn.2025.100237_bib0063","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12030983","article-title":"Revisiting the rotational field TMS method for neurostimulation","volume":"12","author":"Roth","year":"2023","journal-title":"J. Clin. Med."}],"container-title":["Addiction Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772392525000422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772392525000422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:17:41Z","timestamp":1792066661000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772392525000422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":62,"alternative-id":["S2772392525000422"],"URL":"https:\/\/doi.org\/10.1016\/j.addicn.2025.100237","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.11.19.624401","asserted-by":"object"}]},"ISSN":["2772-3925"],"issn-type":[{"value":"2772-3925","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner","name":"articletitle","label":"Article Title"},{"value":"Addiction Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.addicn.2025.100237","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100237"}}