{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T13:06:01Z","timestamp":1791032761616,"version":"4.1.0"},"reference-count":122,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advanced Drug Delivery Reviews"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.addr.2010.09.006","type":"journal-article","created":{"date-parts":[[2010,9,19]],"date-time":"2010-09-19T08:14:25Z","timestamp":1284884065000},"page":"1125-1138","source":"Crossref","is-referenced-by-count":31,"title":["Radionuclide probes for molecular imaging of pancreatic beta-cells"],"prefix":"10.1016","volume":"62","author":[{"given":"Zhanhong","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouad","family":"Kandeel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.addr.2010.09.006_bb0005","first-page":"777","article-title":"General concept and pathophysiological mechanisms of progression of macrovascular complications in diabetes","volume":"68","author":"Kashiwagi","year":"2010","journal-title":"Nippon Rinsho"},{"key":"10.1016\/j.addr.2010.09.006_bb0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s10354-010-0744-y","article-title":"Diabetes and cardiovascular complications","volume":"160","author":"Resl","year":"2010","journal-title":"Wien. Med. Wochenschr."},{"key":"10.1016\/j.addr.2010.09.006_bb0015","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0140-6736(09)62124-3","article-title":"Diabetic retinopathy","volume":"376","author":"Cheung","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2010.09.006_bb0020","first-page":"466","article-title":"Chronic kidney disease in United States Hispanics: a growing public health problem","volume":"19","author":"Lora","year":"2009","journal-title":"Ethn. Dis."},{"key":"10.1016\/j.addr.2010.09.006_bb0025","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1159\/000278694","article-title":"Neuroprotection in diabetic encephalopathy","volume":"6","author":"Fazeli","year":"2009","journal-title":"Neurodegener. Dis."},{"key":"10.1016\/j.addr.2010.09.006_bb0030","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.2174\/138161210791164171","article-title":"MR imaging of pancreatic islets: tracking isolation, transplantation and function","volume":"16","author":"Leoni","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.addr.2010.09.006_bb0035","first-page":"444","article-title":"MRI as a tool to monitor islet transplantation","volume":"5","author":"Medarova","year":"2009","journal-title":"Nat. Rev."},{"key":"10.1016\/j.addr.2010.09.006_bb0040","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2214\/AJR.08.2156","article-title":"MRI in diabetes: first results","volume":"193","author":"Medarova","year":"2009","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.addr.2010.09.006_bb0045","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/cmmi.274","article-title":"In vivo visualization of transplanted pancreatic islets by MRI: comparison between in vivo, histological and electron microscopy findings","volume":"4","author":"Marzola","year":"2009","journal-title":"Contrast Media Mol. Imaging"},{"key":"10.1016\/j.addr.2010.09.006_bb0050","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.2337\/db06-0393","article-title":"Imaging islets labeled with magnetic nanoparticles at 1.5Tesla","volume":"55","author":"Tai","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.addr.2010.09.006_bb0055","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/nm1316","article-title":"In vivo imaging of islet transplantation","volume":"12","author":"Evgenov","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0060","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11307-009-0240-1","article-title":"Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation","volume":"12","author":"Virostko","year":"2010","journal-title":"Mol. Imaging Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0065","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1097\/01.tp.0000203808.84963.13","article-title":"A novel method of monitoring response to islet transplantation: bioluminescent imaging of an NF-\u03baB transgenic mouse model","volume":"81","author":"Roth","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2010.09.006_bb0070","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ceca.2005.06.029","article-title":"Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse","volume":"38","author":"Villalobos","year":"2005","journal-title":"Cell Calcium"},{"key":"10.1016\/j.addr.2010.09.006_bb0075","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0014-5793(93)80702-V","article-title":"Evidence for release of free glucose from muscle during amylin-induced glycogenolysis in rats","volume":"334","author":"Young","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.addr.2010.09.006_bb0080","first-page":"549","article-title":"Fate of 2-deoxy-2-[18F]fluoro-d-glucose in hyperglycemic rats","volume":"6","author":"Malaisse","year":"2000","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0085","first-page":"525","article-title":"Fate of 2-deoxy-2-[18F]fluoro-d-glucose in control and diabetic rats","volume":"5","author":"Malaisse","year":"2000","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0090","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s001250051635","article-title":"On the track to the beta-cell","volume":"44","author":"Malaisse","year":"2001","journal-title":"Diabetologia"},{"key":"10.1016\/j.addr.2010.09.006_bb0095","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1097\/CJI.0b013e31815c5153","article-title":"In vivo tracking of dendritic cells in patients with multiple myeloma","volume":"31","author":"Prince","year":"2008","journal-title":"J. Immunother."},{"key":"10.1016\/j.addr.2010.09.006_bb0100","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.nucmedbio.2008.02.006","article-title":"Tracking of [18F]FDG-labeled natural killer cells to HER2\/neu-positive tumors","volume":"35","author":"Meier","year":"2008","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0105","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00262-006-0181-3","article-title":"In vivo tracking of macrophage activated killer cells to sites of metastatic ovarian carcinoma","volume":"56","author":"Ritchie","year":"2007","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.addr.2010.09.006_bb0110","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.2967\/jnumed.107.042838","article-title":"Dynamic tracking during intracoronary injection of 18F-FDG-labeled progenitor cell therapy for acute myocardial infarction","volume":"48","author":"Doyle","year":"2007","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0115","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.jacc.2006.10.072","article-title":"Role of imaging in cardiac stem cell therapy","volume":"49","author":"Beeres","year":"2007","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.addr.2010.09.006_bb0120","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/01.TP.0000149501.50870.9D","article-title":"Positron-emission tomography imaging of early events after transplantation of islets of Langerhans","volume":"79","author":"Toso","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2010.09.006_bb0125","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1111\/j.1600-6143.2009.02844.x","article-title":"Positron emission tomography in clinical islet transplantation","volume":"9","author":"Eriksson","year":"2009","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.addr.2010.09.006_bb0130","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/cbf.911","article-title":"Pancreatic fate of d-[3H] mannoheptulose","volume":"19","author":"Malaisse","year":"2001","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.addr.2010.09.006_bb0135","first-page":"155","article-title":"Uptake of tritiated d-mannoheptulose by liver, pancreatic exocrine and endocrine cells","volume":"8","author":"Crenier","year":"2001","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0140","first-page":"E298","article-title":"Assessment of islet beta-cell mass in isolated rat pancreases perfused with d-[3H]mannoheptulose","volume":"281","author":"Ladriere","year":"2001","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.addr.2010.09.006_bb0145","first-page":"405","article-title":"Assessment of B-cell mass in isolated islets exposed to d-[3H]mannoheptulose","volume":"7","author":"Malaisse","year":"2001","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0150","first-page":"631","article-title":"Uptake of d-mannoheptulose by normal and tumoral pancreatic islet cells","volume":"7","author":"Ramirez","year":"2001","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0155","first-page":"495","article-title":"Uptake of 1-deoxy-1-[125I]iodo-d-mannoheptulose by different cell types: in vitro and in vivo experiments","volume":"7","author":"Sener","year":"2001","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0160","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/dmrr.331","article-title":"Gene expression profiling in islet biology and diabetes research","volume":"19","author":"Bernal-Mizrachi","year":"2003","journal-title":"Diab.\/Metab. Res. Rev."},{"key":"10.1016\/j.addr.2010.09.006_bb0165","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/0969-8043(93)90103-H","article-title":"Synthesis of a [11C]methoxy derivative of alpha-dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter","volume":"44","author":"DaSilva","year":"1993","journal-title":"Appl. Radiat. Isot."},{"key":"10.1016\/j.addr.2010.09.006_bb0170","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0969-8051(94)90003-5","article-title":"Characterization of [11C]tetrabenazine as an in vivo radioligand for the vesicular monoamine transporter","volume":"21","author":"DaSilva","year":"1994","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0175","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1097\/00004647-199611000-00025","article-title":"Kinetic evaluation of [11C]dihydrotetrabenazine by dynamic PET: measurement of vesicular monoamine transporter","volume":"16","author":"Koeppe","year":"1996","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0180","doi-asserted-by":"crossref","first-page":"4513","DOI":"10.1210\/en.2004-0691","article-title":"Identification of tissue-restricted transcripts in human islets","volume":"145","author":"Maffei","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.addr.2010.09.006_bb0185","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1177\/002215540305100806","article-title":"Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors","volume":"51","author":"Anlauf","year":"2003","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.addr.2010.09.006_bb0190","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.nucmedbio.2006.07.002","article-title":"Visualizing pancreatic beta-cell mass with [11C]DTBZ","volume":"33","author":"Simpson","year":"2006","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0195","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1172\/JCI27645","article-title":"Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model","volume":"116","author":"Souza","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.addr.2010.09.006_bb0200","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.2174\/092986706778521940","article-title":"Current progress in non-invasive imaging of beta cell mass of the endocrine pancreas","volume":"13","author":"Souza","year":"2006","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0205","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1007\/s00259-007-0648-2","article-title":"Whole body [11C]-dihydrotetrabenazine imaging of baboons: biodistribution and human radiation dosimetry estimates","volume":"35","author":"Murthy","year":"2008","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.addr.2010.09.006_bb0210","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00109-007-0242-x","article-title":"VMAT2 gene expression and function as it applies to imaging beta-cell mass","volume":"86","author":"Harris","year":"2008","journal-title":"J. Mol. Med."},{"issue":"Suppl 4","key":"10.1016\/j.addr.2010.09.006_bb0215","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1463-1326.2008.00943.x","article-title":"VMAT2 quantitation by PET as a biomarker for beta-cell mass in health and disease","volume":"10","author":"Freeby","year":"2008","journal-title":"Diab. Obes. Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0220","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.2967\/jnumed.109.074492","article-title":"Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas","volume":"51","author":"Fagerholm","year":"2010","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0225","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.surg.2009.08.005","article-title":"The utility of [11C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal\u2013jejunal bypass","volume":"147","author":"Inabnet","year":"2010","journal-title":"Surgery"},{"key":"10.1016\/j.addr.2010.09.006_bb0230","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.2967\/jnumed.108.051680","article-title":"In vivo imaging of beta-cell mass in rats using 18F-FP-(+)-DTBZ: a potential PET ligand for studying diabetes mellitus","volume":"49","author":"Kung","year":"2008","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0235","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.nucmedbio.2008.08.004","article-title":"In vivo imaging of vesicular monoamine transporter 2 in pancreas using an 18F epoxide derivative of tetrabenazine","volume":"35","author":"Kung","year":"2008","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0240","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.nucmedbio.2009.12.004","article-title":"In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass","volume":"37","author":"Eriksson","year":"2010","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0245","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s00259-003-1350-7","article-title":"Neurofunctional imaging of the pancreas utilizing the cholinergic PET radioligand [18F]4-fluorobenzyltrozamicol","volume":"31","author":"Clark","year":"2004","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.addr.2010.09.006_bb0250","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1089\/dia.2008.0024","article-title":"Dual radiotracer analysis of cholinergic neuronal changes in prediabetic mouse pancreas","volume":"11","author":"Clark","year":"2009","journal-title":"Diab. Technol. Ther."},{"key":"10.1016\/j.addr.2010.09.006_bb0255","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1089\/dia.2008.0113","article-title":"Enhanced cholinergic response in pancreata of nonhuman primates with impaired glucose tolerance shown on [18F]fluorobenzyltrozamicol positron emission tomography","volume":"11","author":"Clark","year":"2009","journal-title":"Diab. Technol. Ther."},{"key":"10.1016\/j.addr.2010.09.006_bb0260","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.bbrc.2003.12.182","article-title":"Systematic screening of potential beta-cell imaging agents","volume":"314","author":"Sweet","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.addr.2010.09.006_bb0265","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0303-7207(86)90034-1","article-title":"Aromatic amino acids and pancreatic islet function: a comparison of l-tryptophan and l-5-hydroxytryptophan","volume":"48","author":"Lindstrom","year":"1986","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.addr.2010.09.006_bb0270","first-page":"161","article-title":"Presence of DOPA decarboxylase and its localisation in adult rat pancreatic islet cells","volume":"23","author":"Borelli","year":"1997","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0275","doi-asserted-by":"crossref","DOI":"10.2174\/138161210791164090","article-title":"Clinical PET imaging of insulinoma and beta-cell hyperplasia","author":"Kauhanen","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.addr.2010.09.006_bb0280","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.2967\/jnumed.109.065664","article-title":"18F-FDOPA: a multiple-target molecule","volume":"50","author":"Minn","year":"2009","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0285","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1148\/radiol.2532081445","article-title":"Value of 18F-fluoro-l-DOPA PET in the preoperative localization of focal lesions in congenital hyperinsulinism","volume":"253","author":"Capito","year":"2009","journal-title":"Radiology"},{"key":"10.1016\/j.addr.2010.09.006_bb0290","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1210\/jc.2007-2036","article-title":"Evaluation of [18F]fluoro-l-DOPA positron emission tomography-computed tomography for surgery in focal congenital hyperinsulinism","volume":"93","author":"Barthlen","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0295","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1097\/RCT.0b013e318031f55c","article-title":"[18F]Fluoro-l-dopa PET\/CT in congenital hyperinsulinism","volume":"31","author":"Subramaniam","year":"2007","journal-title":"J. Comput. Assist. Tomogr."},{"key":"10.1016\/j.addr.2010.09.006_bb0300","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1007\/s00259-007-0498-y","article-title":"The added value of [18F]fluoro-l-DOPA PET in the diagnosis of hyperinsulinism of infancy: a retrospective study involving 49 children","volume":"34","author":"Ribeiro","year":"2007","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.addr.2010.09.006_bb0305","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1210\/jc.2006-1479","article-title":"Fluorine-18-l-dihydroxyphenylalanine (18F-DOPA) positron emission tomography as a tool to localize an insulinoma or \u03b2-cell hyperplasia in adult patients","volume":"92","author":"Kauhanen","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0310","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jpeds.2006.08.028","article-title":"Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan","volume":"150","author":"Hardy","year":"2007","journal-title":"J. Pediatr."},{"key":"10.1016\/j.addr.2010.09.006_bb0315","doi-asserted-by":"crossref","first-page":"4706","DOI":"10.1210\/jc.2007-1637","article-title":"Accuracy of [18F]fluorodopa positron emission tomography for diagnosing and localizing focal congenital hyperinsulinism","volume":"92","author":"Hardy","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.addr.2010.09.006_bb0320","first-page":"560","article-title":"Characterization of hyperinsulinism in infancy assessed with PET and 18F-fluoro-l-DOPA","volume":"46","author":"Ribeiro","year":"2005","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0325","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0969-8051(94)00117-3","article-title":"Fluorinated benzamide neuroleptics\u2013III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer","volume":"22","author":"Mukherjee","year":"1995","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0330","first-page":"1947","article-title":"18F-Fallypride PET to monitor pancreatic beta cell loss in diabetes mellitus","volume":"50","author":"Garcia","year":"2009","journal-title":"J. Nucl. Med. Meet. Abstr."},{"key":"10.1016\/j.addr.2010.09.006_bb0335","first-page":"88","article-title":"Dual probe microPET imaging of rodent pancreas","volume":"51","author":"Garcia","year":"2010","journal-title":"J. Nucl. Med. Meet. Abstr."},{"key":"10.1016\/j.addr.2010.09.006_bb0340","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0079-6107(89)90013-8","article-title":"Electrophysiology of the pancreatic beta-cell","volume":"54","author":"Ashcroft","year":"1989","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0345","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1152\/physrev.1998.78.1.227","article-title":"Toward understanding the assembly and structure of KATP channels","volume":"78","author":"Aguilar-Bryan","year":"1998","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.addr.2010.09.006_bb0350","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2337\/diacare.1.3.189","article-title":"Sulfonylurea drugs: mechanism of antidiabetic action and therapeutic usefulness","volume":"1","author":"Lebovitz","year":"1978","journal-title":"Diab. Care"},{"key":"10.1016\/j.addr.2010.09.006_bb0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-0029-1211414","article-title":"Sulfonylurea receptors and mechanism of sulfonylurea action","volume":"104","author":"Panten","year":"1996","journal-title":"Exp. Clin. Endocrinol. Diab."},{"issue":"Suppl 37","key":"10.1016\/j.addr.2010.09.006_bb0360","first-page":"16","article-title":"Metabolic effects of sulfonylurea drugs. A review","volume":"15","author":"Groop","year":"1983","journal-title":"Ann. Clin. Res."},{"key":"10.1016\/j.addr.2010.09.006_bb0365","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0140-6736(85)90403-9","article-title":"The sulphonylurea receptor may be an ATP-sensitive potassium channel","volume":"2","author":"Sturgess","year":"1985","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2010.09.006_bb0370","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/j.1476-5381.1994.tb17078.x","article-title":"Location of the sulphonylurea receptor at the cytoplasmic face of the beta-cell membrane","volume":"113","author":"Schwanstecher","year":"1994","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.addr.2010.09.006_bb0375","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/sj.bjp.0702763","article-title":"Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes","volume":"128","author":"Meyer","year":"1999","journal-title":"Br. J. Pharmacol."},{"issue":"Pt 3","key":"10.1016\/j.addr.2010.09.006_bb0380","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1042\/bj2770619","article-title":"Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15","volume":"277","author":"Niki","year":"1991","journal-title":"Biochem. J."},{"key":"10.1016\/j.addr.2010.09.006_bb0385","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1016\/S0021-9258(18)69106-9","article-title":"Characterization of the sulfonylurea receptor on beta cell membranes","volume":"263","author":"Gaines","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0390","doi-asserted-by":"crossref","first-page":"15840","DOI":"10.1016\/S0021-9258(18)47664-8","article-title":"The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells","volume":"262","author":"Schmid-Antomarchi","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0395","doi-asserted-by":"crossref","first-page":"14934","DOI":"10.1016\/S0021-9258(18)42130-8","article-title":"Co-expression of sulfonylurea receptors and KATP channels in hamster insulinoma tumor (HIT) cells. Evidence for direct association of the receptor with the channel","volume":"267","author":"Aguilar-Bryan","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0400","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1021\/jm01237a002","article-title":"Hypoglycemic activity in relation to chemical structure of potential oral antidiabetic substances. I. 1-Sulfonyl-3-alkylureas","volume":"51","author":"Hoekfelt","year":"1962","journal-title":"J. Med. Pharm. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0405","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/jlcr.438","article-title":"Synthesis of fluorine-18 labeled sulfonureas as beta-cell imaging agents","volume":"44","author":"Grace","year":"2001","journal-title":"J. Labelled Comp. Radiopharm."},{"key":"10.1016\/j.addr.2010.09.006_bb0410","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.nucmedbio.2003.12.003","article-title":"Synthesis and evaluation of fluorine-18 labeled glyburide analogs as beta-cell imaging agents","volume":"31","author":"Schmitz","year":"2004","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0415","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/jlcr.599","article-title":"Radiosynthesis of 1-(4-(2-[18F]fluoroethoxy)benzenesulfonyl)-3-butyl urea: a potential \u03b2-cell imaging agent","volume":"45","author":"Ralf","year":"2002","journal-title":"J. Labelled Comp. Radiopharm."},{"key":"10.1016\/j.addr.2010.09.006_bb0420","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1055\/s-2005-865711","article-title":"In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans","volume":"113","author":"Schneider","year":"2005","journal-title":"Exp. Clin. Endocrinol. Diab."},{"key":"10.1016\/j.addr.2010.09.006_bb0425","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1021\/bc0200069","article-title":"Improvement of pharmacokinetics of radioiodinated Tyr(3)-octreotide by conjugation with carbohydrates","volume":"13","author":"Schottelius","year":"2002","journal-title":"Bioconjug. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0430","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.regpep.2006.11.004","article-title":"Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imaging agents","volume":"139","author":"Schneider","year":"2007","journal-title":"Regul. Pept."},{"key":"10.1016\/j.addr.2010.09.006_bb0435","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2337\/diabetes.47.3.345","article-title":"Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes","volume":"47","author":"Fuhlendorff","year":"1998","journal-title":"Diabetes"},{"key":"10.1016\/j.addr.2010.09.006_bb0440","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.nucmedbio.2004.01.007","article-title":"Synthesis and evaluation of (S)-2-(2-[18F]fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)-butyl-carbamoyl]-methyl)-benzoic acid ([18F]repaglinide): a promising radioligand for quantification of pancreatic beta-cell mass with positron emission tomography (PET)","volume":"31","author":"Wangler","year":"2004","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0445","doi-asserted-by":"crossref","first-page":"5205","DOI":"10.1016\/j.bmcl.2004.07.059","article-title":"Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent","volume":"14","author":"Wangler","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.addr.2010.09.006_bb0450","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0969-8051(97)00160-1","article-title":"Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET","volume":"25","author":"Alauddin","year":"1998","journal-title":"Nucl. Med. Biol."},{"key":"10.1016\/j.addr.2010.09.006_bb0455","first-page":"1682","article-title":"Preclinical evaluation of the penciclovir analog 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET","volume":"42","author":"Alauddin","year":"2001","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0460","first-page":"1072","article-title":"Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression","volume":"43","author":"Tjuvajev","year":"2002","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0465","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1162\/1535350041464900","article-title":"Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model","volume":"3","author":"Alauddin","year":"2004","journal-title":"Mol. Imaging"},{"key":"10.1016\/j.addr.2010.09.006_bb0470","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.mnm.0000186609.12895.20","article-title":"18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers","volume":"27","author":"Buursma","year":"2006","journal-title":"Nucl. Med. Commun."},{"key":"10.1016\/j.addr.2010.09.006_bb0475","first-page":"706","article-title":"Preclinical safety evaluation of 18F-FHBG: a PET reporter probe for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk's expression","volume":"47","author":"Yaghoubi","year":"2006","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0480","doi-asserted-by":"crossref","first-page":"713","DOI":"10.2967\/jnumed.107.046425","article-title":"A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs","volume":"49","author":"Likar","year":"2008","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0485","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.ymthe.2006.08.007","article-title":"Long-term monitoring of transplanted islets using positron emission tomography","volume":"14","author":"Lu","year":"2006","journal-title":"Mol. Ther."},{"key":"10.1016\/j.addr.2010.09.006_bb0490","doi-asserted-by":"crossref","first-page":"11294","DOI":"10.1073\/pnas.0603909103","article-title":"Noninvasive imaging of islet grafts using positron-emission tomography","volume":"103","author":"Lu","year":"2006","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.addr.2010.09.006_bb0495","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1038\/nm1458","article-title":"Quantitative micro positron emission tomography (PET) imaging for the in vivo determination of pancreatic islet graft survival","volume":"12","author":"Kim","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0500","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2967\/jnumed.107.043430","article-title":"Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT","volume":"49","author":"Tai","year":"2008","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0505","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1152\/physrev.00034.2006","article-title":"The physiology of glucagon-like peptide 1","volume":"87","author":"Holst","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.addr.2010.09.006_bb0510","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1053\/j.gastro.2007.03.054","article-title":"Biology of incretins: GLP-1 and GIP","volume":"132","author":"Baggio","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.addr.2010.09.006_bb0515","doi-asserted-by":"crossref","first-page":"19650","DOI":"10.1016\/S0021-9258(19)36565-2","article-title":"Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells","volume":"268","author":"Goke","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0520","doi-asserted-by":"crossref","first-page":"7402","DOI":"10.1016\/S0021-9258(18)42531-8","article-title":"Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas","volume":"267","author":"Eng","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2010.09.006_bb0525","series-title":"70th ADA Scientific Sessions abstract","article-title":"Highly constrained GLP-1 analogues as non-invasive PET Imaging Probes for Pancreatic Beta-Cells","author":"Ahn","year":"2010"},{"key":"10.1016\/j.addr.2010.09.006_bb0530","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.regpep.2006.07.005","article-title":"A new technique for in vivo imaging of specific GLP-1 binding sites: first results in small rodents","volume":"137","author":"Gotthardt","year":"2006","journal-title":"Regul. Pept."},{"key":"10.1016\/j.addr.2010.09.006_bb0535","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.bbrc.2009.09.014","article-title":"GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging","volume":"389","author":"Mukai","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.addr.2010.09.006_bb0540","first-page":"195","article-title":"Synthesis and evaluation of F-18-exendin as a potential biomarker to measure pancreatic beta-cell mass","volume":"51","author":"Wang","year":"2010","journal-title":"J. Nucl. Med. Meet. Abstr."},{"key":"10.1016\/j.addr.2010.09.006_bb0545","series-title":"70th ADA Scientific Sessions abstract","article-title":"Non-Invasive PET Imaging of Pancreatic Islets Targeting Glucagon-Like Peptide-1 Receptors","author":"Toyoda","year":"2010"},{"key":"10.1016\/j.addr.2010.09.006_bb0550","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S1065-6995(02)90952-2","article-title":"Specific monoclonal antibodies against the surface of rat islet beta cells","volume":"26","author":"Konidaris","year":"2002","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.addr.2010.09.006_bb0555","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1007\/BF00400250","article-title":"Monoclonal antibody-mediated cytotoxicity against rat beta cells detected in vitro does not cause beta-cell destruction in vivo","volume":"35","author":"Ziegler","year":"1992","journal-title":"Diabetologia"},{"key":"10.1016\/j.addr.2010.09.006_bb0560","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1699-0463.1988.tb05313.x","article-title":"Antigen expression of the pancreatic beta-cells is dependent on their functional state, as shown by a specific, BB rat monoclonal autoantibody IC2","volume":"96","author":"Buschard","year":"1988","journal-title":"APMIS"},{"key":"10.1016\/j.addr.2010.09.006_bb0565","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/cbf.903","article-title":"Pancreatic fate of a 125I-labelled mouse monoclonal antibody directed against pancreatic B-cell surface ganglioside(s) in control and diabetic rats","volume":"19","author":"Ladriere","year":"2001","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.addr.2010.09.006_bb0570","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.2337\/diabetes.50.10.2231","article-title":"Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes","volume":"50","author":"Moore","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.addr.2010.09.006_bb0575","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1055\/s-2005-865716","article-title":"Quantitative evaluation of a monoclonal antibody and its fragment as potential markers for pancreatic beta cell mass","volume":"113","author":"Hampe","year":"2005","journal-title":"Exp. Clin. Endocrinol. Diab."},{"key":"10.1016\/j.addr.2010.09.006_bb0580","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1006\/jsre.1995.1136","article-title":"Somatostatin inhibits B-cell secretion via a subtype-2 somatostatin receptor in the isolated perfused human pancreas","volume":"59","author":"Moldovan","year":"1995","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.addr.2010.09.006_bb0585","doi-asserted-by":"crossref","first-page":"10836","DOI":"10.1073\/pnas.95.18.10836","article-title":"Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2","volume":"95","author":"Yang","year":"1998","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.addr.2010.09.006_bb0590","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1126\/science.282.5389.737","article-title":"Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry","volume":"282","author":"Rohrer","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.addr.2010.09.006_bb0595","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.apradiso.2006.01.009","article-title":"Synthesis and evaluation of radioiodinated substituted beta-naphthylalanine as a potential probe for pancreatic beta-cells imaging","volume":"64","author":"Amartey","year":"2006","journal-title":"Appl. Radiat. Isot."},{"key":"10.1016\/j.addr.2010.09.006_bb0600","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/nm0396-299","article-title":"Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries","volume":"2","author":"Barry","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.addr.2010.09.006_bb0605","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.2337\/diabetes.54.7.2103","article-title":"Peptide-mediated targeting of the islets of Langerhans","volume":"54","author":"Samli","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.addr.2010.09.006_bb0610","first-page":"4558","article-title":"Advances in molecular imaging of pancreatic beta cells","volume":"13","author":"Lin","year":"2008","journal-title":"Front. Biosci."}],"container-title":["Advanced Drug Delivery Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X10001845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X10001845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T05:32:04Z","timestamp":1636522324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169409X10001845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":122,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0169409X10001845"],"URL":"https:\/\/doi.org\/10.1016\/j.addr.2010.09.006","relation":{},"ISSN":["0169-409X"],"issn-type":[{"value":"0169-409X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}