{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T21:19:29Z","timestamp":1791062369452,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","issue":"4-5","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KQ0902N"],"award-info":[{"award-number":["01KQ0902N"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KQ0902O"],"award-info":[{"award-number":["01KQ0902O"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["FKZ 0315575"],"award-info":[{"award-number":["FKZ 0315575"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WA 1649\/3-1"],"award-info":[{"award-number":["WA 1649\/3-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advanced Drug Delivery Reviews"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.addr.2011.01.011","type":"journal-article","created":{"date-parts":[[2011,2,3]],"date-time":"2011-02-03T04:15:27Z","timestamp":1296706527000},"page":"367-374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Tracheobronchial bio-engineering: Biotechnology fulfilling unmet medical needs"],"prefix":"10.1016","volume":"63","author":[{"given":"Thorsten","family":"Walles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.addr.2011.01.011_bb0005","series-title":"Surgery of the trachea and bronchi","first-page":"839","article-title":"Tracheal replacement","author":"Grillo HC","year":"2004"},{"key":"10.1016\/j.addr.2011.01.011_bb0010","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1586\/17434440.1.2.241","article-title":"Bioartificial tracheal grafts: can tissue engineering keep its promise?","volume":"1","author":"Walles","year":"2004","journal-title":"Expert Rev. Med. Devices"},{"key":"10.1016\/j.addr.2011.01.011_bb0015","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1056\/NEJMoa0810653","article-title":"Leuven Tracheal Transplant Group, Tracheal allotransplantation after withdrawal of immune-suppressive therapy","volume":"362","author":"Delaere","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.addr.2011.01.011_bb0020","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1016\/j.transproceed.2007.06.072","article-title":"Management of larynx and trachea donors","volume":"39","author":"Duque","year":"2007","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.addr.2011.01.011_bb0025","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1586\/17434440.5.5.605","article-title":"Clinical tracheal replacement: transplantation, bioprostheses and artificial grafts","volume":"5","author":"Steger","year":"2008","journal-title":"Expert Rev. Med. Devices"},{"key":"10.1016\/j.addr.2011.01.011_bb0030","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/MAT.0b013e3180616b5d","article-title":"Tracheal replacements: Part 1","volume":"53","author":"Kucera","year":"2007","journal-title":"ASAIO J."},{"key":"10.1016\/j.addr.2011.01.011_bb0035","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1097\/MAT.0b013e318145ba13","article-title":"Tracheal replacements: Part 2","volume":"53","author":"Doss","year":"2007","journal-title":"ASAIO J."},{"key":"10.1016\/j.addr.2011.01.011_bb0040","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1111\/j.1582-4934.2010.01073.x","article-title":"Moving towards in situ tracheal regeneration: the bionic tissue engineered transplantation approach","volume":"14","author":"Bader","year":"2010","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.addr.2011.01.011_bb0045","series-title":"Surgery of the trachea and bronchi","first-page":"1","article-title":"Development of tracheal surgery: a historical review","author":"Grillo","year":"2004"},{"key":"10.1016\/j.addr.2011.01.011_bb0050","first-page":"175","article-title":"Airway stenting, Chest","volume":"13","author":"Wood","year":"2003","journal-title":"Clin. North Am."},{"key":"10.1016\/j.addr.2011.01.011_bb0055","first-page":"621","article-title":"Tracheal transplantation: beyond the replacement of a simple conduit","volume":"14","author":"Macchiarini","year":"1998","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0060","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1165\/rcmb.2004-0279OC","article-title":"Identification and characterization of human pulmonary dentritic cells","volume":"32","author":"Demedts","year":"2005","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.addr.2011.01.011_bb0065","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3109\/00016489009122530","article-title":"Tracheal transplantation: demonstration of HLA class II subregion gene products on human trachea","volume":"110","author":"Bujia","year":"1990","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0070","series-title":"Surgery of the trachea and bronchi","first-page":"39","article-title":"Anatomy of the trachea","author":"Grillo","year":"2004"},{"key":"10.1016\/j.addr.2011.01.011_bb0075","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/bjs.18003815008","article-title":"Resection and reconstruction of the intrathoracic trachea","volume":"38","author":"Belsey","year":"1950","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0080","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1126\/science.8493529","article-title":"Tissue engineering","volume":"260","author":"Langer","year":"1993","journal-title":"Science"},{"issue":"Suppl","key":"10.1016\/j.addr.2011.01.011_bb0085","first-page":"S132","article-title":"Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation","volume":"354","author":"Vacanti","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0090","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1089\/hum.2009.035","article-title":"Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury","volume":"20","author":"Leblond","year":"2009","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.addr.2011.01.011_bb0095","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1089\/ten.tea.2007.0412","article-title":"Origins","volume":"15","author":"Lysaght","year":"2009","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.addr.2011.01.011_bb0100","doi-asserted-by":"crossref","first-page":"M834","DOI":"10.1097\/00002480-199407000-00115","article-title":"Experimental reconstruction of the intrathoracic trachea using a new prosthesis made from collagen grafted mesh","volume":"40","author":"Okumura","year":"1994","journal-title":"ASAIO J."},{"key":"10.1016\/j.addr.2011.01.011_bb0105","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/S0142-9612(03)00500-3","article-title":"Animal models for tracheal research","volume":"25","author":"Ten Hallers","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2011.01.011_bb0110","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.athoracsur.2009.09.005","article-title":"Tracheal replacement with a silicones stented fresh aortic allograft in sheep","volume":"89","author":"Tsukada","year":"2010","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0115","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/TP.0b013e3181cd4ad3","article-title":"Tissue-engineered tracheal transplantation","volume":"89","author":"Baiguera","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2011.01.011_bb0120","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/000348940511400603","article-title":"Regenerative medicine of the trachea: the first human case","volume":"114","author":"Omori","year":"2005","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0125","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.jtcvs.2004.02.042","article-title":"First human transplantation of a bioengineered airway tissue","volume":"128","author":"Macchiarini","year":"2004","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0130","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1056\/NEJMc066336","article-title":"Tracheal replacement with aortic allografts","volume":"355","author":"Wurtz","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.addr.2011.01.011_bb0135","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(08)61598-6","article-title":"Clinical transplantation of a tissue-engineered airway","volume":"372","author":"Macchiarini","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0140","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1177\/000348940811700908","article-title":"Clinical application of in situ tissue engineering using a scaffolding technique for reconstruction of the larynx and trachea","volume":"117","author":"Omori","year":"2008","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0145","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1177\/000348940811700609","article-title":"Regeneration of the trachea using a bioengineered scaffold with adipose-derived stem cells","volume":"117","author":"Suzuki","year":"2008","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0150","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1177\/000348940911801109","article-title":"Bioengineered trachea with fibroblasts in a rabbit model","volume":"118","author":"Okano","year":"2009","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0155","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.1016\/j.biomaterials.2010.02.027","article-title":"A tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells","volume":"31","author":"Kobayashi","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2011.01.011_bb0160","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jtcvs.2009.04.006","article-title":"Biodegradable polymer coating promotes the epithelization of tissue-engineered airway prostheses","volume":"139","author":"Sato","year":"2010","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0165","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.jtcvs.2008.07.072","article-title":"In situ tissue engineering for tracheal reconstruction using a luminar remodeling type of artificial trachea","volume":"138","author":"Nakamura","year":"2009","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0170","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1177\/000348941011901009","article-title":"Potential of induced pluripotent stem cells for the regeneration of the tracheal wall","volume":"119","author":"Imaizumi","year":"2010","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0175","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1016\/S0003-4975(03)00120-6","article-title":"Long-term evaluation of the replacement of the trachea with an autologous aortic graft","volume":"75","author":"Martinod","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0180","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.athoracsur.2004.08.035","article-title":"Tracheal regeneration following tracheal replacement with an allogenic aorta","volume":"79","author":"Martinod","year":"2005","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0185","series-title":"Biomaterials Research Advances","first-page":"183","article-title":"Strategies for Scaffold Vascularization in Tissue Engineering","author":"Walles","year":"2007"},{"key":"10.1016\/j.addr.2011.01.011_bb0190","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/j.athoracsur.2010.01.034","article-title":"Tracheal replacement with banked cryopreserved aortic allograft","volume":"89","author":"Wurtz","year":"2010","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0195","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jtcvs.2010.01.043","article-title":"Surgical technique and results of tracheal and carinal replacement with aortic allografts for salivary gland-type carcinoma","volume":"140","author":"Wurtz","year":"2010","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0200","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.athoracsur.2003.08.083","article-title":"Replacement of the trachea with an autologous aortic graft","volume":"78","author":"Mertsching","year":"2004","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0205","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.rmr.2010.04.001","article-title":"Advances in tracheal surgery: are we close to finding the ideal tracheal substitute?","volume":"27","author":"Martinod","year":"2010","journal-title":"Rev. Mal. Respir."},{"key":"10.1016\/j.addr.2011.01.011_bb0210","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.athoracsur.2008.11.038","article-title":"Tracheal replacement with cryopreserved, decellularized, or glutaraldehyde-treated aortic allografts","volume":"87","author":"Seguin","year":"2009","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0215","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1378\/chest.09-1275","article-title":"Tracheal replacement with cryopreserved allogenic aorta","volume":"137","author":"Makris","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.addr.2011.01.011_bb0220","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.semcdb.2008.12.008","article-title":"Biomimetic approach to tissue engineering","volume":"20","author":"Grayson","year":"2009","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.addr.2011.01.011_bb0225","doi-asserted-by":"crossref","first-page":"6610","DOI":"10.1016\/j.biomaterials.2005.04.048","article-title":"Engineering of a vascularized scaffold for artificial tissue and organ generation","volume":"26","author":"Mertsching","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2011.01.011_bb0230","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.jtcvs.2004.07.036","article-title":"Experimental generation of a tissue-engineered functional and vascularized trachea","volume":"128","author":"Walles","year":"2004","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0235","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/01.TP.0000164144.25619.01","article-title":"Tissue remodeling in a bioartificial fibromuscular patch following transplantation in a human","volume":"80","author":"Walles","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2011.01.011_bb0240","first-page":"23","article-title":"Bioartificial transplants in reconstructive surgery: translation and economic gains for the health care system","volume":"1","author":"Altmayer","year":"2009","journal-title":"Reg. Med."},{"key":"10.1016\/j.addr.2011.01.011_bb0245","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/j.jtcvs.2007.12.092","article-title":"Pumpless extracorporeal gas exchange aiding central airway surgery","volume":"136","author":"Walles","year":"2008","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0250","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/TP.0b013e3181ac15e1","article-title":"Generation and transplantation of an autologous vascularized bioartificial human tissue","volume":"88","author":"Mertsching","year":"2009","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2011.01.011_bb0255","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1432-2277.2005.00082.x","article-title":"Tracheal matrices, obtained by a detergent-enzymatic method, support in vitro the adhesion of chondrocytes and tracheal epithelial cells","volume":"18","author":"Conconi","year":"2005","journal-title":"Transpl. Int."},{"key":"10.1016\/j.addr.2011.01.011_bb0260","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/art.10842","article-title":"Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach","volume":"48","author":"Kafienah","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.addr.2011.01.011_bb0265","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1634\/stemcells.2007-0059","article-title":"Pharmacological regulation of adult stem cells: chondrogenesis can be induced using a synthetic inhibitor of the retinoic acid receptor","volume":"25","author":"Kafienah","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.addr.2011.01.011_bb0270","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1016\/S0140-6736(08)61599-8","article-title":"Tissue-engineered airway replacement","volume":"372","author":"Sato","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0275","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0140-6736(09)60428-1","article-title":"Clinical transplantation of a tissue-engineered airway","volume":"373","author":"Wu","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0280","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0140-6736(09)60429-3","article-title":"Clinical transplantation of a tissue-engineered airway","volume":"373","author":"Delaere","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0285","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0140-6736(09)60430-X","article-title":"Clinical transplantation of a tissue-engineered airway","volume":"373","author":"Zhang","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.addr.2011.01.011_bb0290","series-title":"An introduction to tissue-biomaterial interactions, John Wiley & Sons","author":"Dee","year":"2002"},{"key":"10.1016\/j.addr.2011.01.011_bb0295","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.smim.2007.11.004","article-title":"Foreign body reaction to biomaterials","volume":"20","author":"Anderson","year":"2008","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.addr.2011.01.011_bb0300","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.smim.2007.11.003","article-title":"Immune response to biologic scaffold materials","volume":"20","author":"Badylak","year":"2008","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.addr.2011.01.011_bb0305","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/039139880302600308","article-title":"Acellular implantation \u2013 no alternative to tissue engineering","volume":"26","author":"Walles","year":"2003","journal-title":"Int. J. Artif. Organs"},{"key":"10.1016\/j.addr.2011.01.011_bb0310","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1399-0012.1991.tb00116.x","article-title":"Immunological behaviour of preserved human tracheal allografts: immunological monitoring of a human tracheal recipient","volume":"5","author":"Bujia","year":"1991","journal-title":"Clin. Transplant."},{"issue":"Suppl I","key":"10.1016\/j.addr.2011.01.011_bb0315","first-page":"247","article-title":"Transplantation von Larynx und Trachea beim Menschen. Verhandlungsbericht der Deutschen Gesellschaft fur Hals-Nasen-Ohren-Heilkunde, Europ","author":"Herberhold","year":"1992","journal-title":"Arch. Oto-Rhinol-Laryngol."},{"key":"10.1016\/j.addr.2011.01.011_bb0320","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/01.tp.0000250598.29377.13","article-title":"Replacement of human anterior cruciate ligaments with pig ligaments: a model for anti-non-gal antibody response in long-term xenotransplantation","volume":"83","author":"Stone","year":"2007","journal-title":"Transplantation"},{"key":"10.1016\/j.addr.2011.01.011_bb0325","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1089\/10763270050044416","article-title":"Galalpha(1, 3)Gal epitope in porcine small intestinal submucosa","volume":"6","author":"McPherson","year":"2000","journal-title":"Tissue Eng."},{"key":"10.1016\/j.addr.2011.01.011_bb0330","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1365-2362.2005.01441.x","article-title":"Alpha-Gal on bioprostheses: xenograft immune response in cardiac surgery","volume":"35","author":"Konakci","year":"2005","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.addr.2011.01.011_bb0335","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1161\/CIRCULATIONAHA.104.473629","article-title":"Tissue engineering of heart valves. Decellularized porcine and human valve scaffolds differ importantly in residual potential to attract moncytic cells","volume":"111","author":"Reider","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.addr.2011.01.011_bb0340","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0966-3274(01)00044-2","article-title":"Natural anti-galactose alpha 1, 3 galactose antibodies delay, but do not prevent the acceptance of extracellular matrix xenografts","volume":"10","author":"Raeder","year":"2002","journal-title":"Transpl. Immunol."},{"key":"10.1016\/j.addr.2011.01.011_bb0345","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.smim.2007.12.008","article-title":"Innate and adptive immune responses in tissue engineering","volume":"20","author":"Sefton","year":"2008","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.addr.2011.01.011_bb0350","doi-asserted-by":"crossref","first-page":"3520","DOI":"10.1016\/j.biomaterials.2010.01.067","article-title":"Hydrated xenogeneic decellularized tracheal matrix as a scaffold for tracheal reconstruction","volume":"32","author":"Remlinger","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2011.01.011_bb0355","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1038\/nbt0705-821","article-title":"Engineering vascularized tissue","volume":"23","author":"Jain","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.addr.2011.01.011_bb0360","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1089\/ten.tea.2008.0695","article-title":"Study of the crosstalk between hepatocytes and endothelial cells using a novel multicompartmental bioreactor: a comparison between connected cultures and cocultures","volume":"15","author":"Guzzardi","year":"2009","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.addr.2011.01.011_bb0365","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1016\/j.biomaterials.2009.05.004","article-title":"Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone-starch scaffold and the in vitro development of vascularization","volume":"30","author":"Santos","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2011.01.011_bb0370","doi-asserted-by":"crossref","first-page":"7046","DOI":"10.1073\/pnas.0802463105","article-title":"Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair","volume":"105","author":"Zani","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.addr.2011.01.011_bb0375","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jbiotec.2010.03.015","article-title":"Vascularised human tissue models: a new approach for the refinement of biomedical research","volume":"148","author":"Schanz","year":"2010","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.addr.2011.01.011_bb0380","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1057\/jcb.2008.32","article-title":"ATMP in practice: towards a new industry landscape in tissue engineering","volume":"15","author":"Br\u00e9vignon-Dodin","year":"2009","journal-title":"J. Commer. Biotechnol."},{"key":"10.1016\/j.addr.2011.01.011_bb0385","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1586\/17434440.6.2.109","article-title":"Europe's advanced therapy medicinal products: chances and challenges","volume":"6","author":"Mertsching","year":"2009","journal-title":"Expert Rev. Med. Devices"},{"key":"10.1016\/j.addr.2011.01.011_bb0390","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jtcvs.2010.06.037","article-title":"Randomized clinical trials for new surgical operations: square peg in a round hole?","volume":"140","author":"Cooper","year":"2010","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.addr.2011.01.011_bb0395","doi-asserted-by":"crossref","first-page":"R790","DOI":"10.1016\/j.cub.2009.07.029","article-title":"Biology and physics of cell shape changes in development","volume":"19","author":"Paluch","year":"2009","journal-title":"Curr. Biol."},{"key":"10.1016\/j.addr.2011.01.011_bb0400","doi-asserted-by":"crossref","first-page":"309","DOI":"10.33549\/physiolres.931776","article-title":"Osteogenic cells on bio-inspired materials for bone tissue engineering","volume":"59","author":"Vagask\u00e1","year":"2010","journal-title":"Physiol. Res."},{"key":"10.1016\/j.addr.2011.01.011_bb0405","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.smim.2007.12.005","article-title":"The effect of three-dimensional matrix-embedding of endothelial cells on the humoral and cellular immune response","volume":"20","author":"Methe","year":"2008","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.addr.2011.01.011_bb0410","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.jtcvs.2008.09.085","article-title":"Structural and morphologic evaluation of a novel detergent-enzymatic tissue-engineered tracheal tubular matrix","volume":"138","author":"Jungebluth","year":"2009","journal-title":"J. Thorac. Cardiovasc. Surg."}],"container-title":["Advanced Drug Delivery Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X11000159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X11000159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T04:33:00Z","timestamp":1759206780000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169409X11000159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":82,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0169409X11000159"],"URL":"https:\/\/doi.org\/10.1016\/j.addr.2011.01.011","relation":{},"ISSN":["0169-409X"],"issn-type":[{"value":"0169-409X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tracheobronchial bio-engineering: Biotechnology fulfilling unmet medical needs","name":"articletitle","label":"Article Title"},{"value":"Advanced Drug Delivery Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.addr.2011.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}