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Soc."},{"key":"10.1016\/j.addr.2021.02.005_b0530","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1089\/ars.2011.3959","article-title":"Differential antibacterial activity against Pseudomonas aeruginosa by carbon monoxide-releasing molecules","volume":"16","author":"Desmard","year":"2012","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.addr.2021.02.005_b0535","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1021\/ml500399r","article-title":"Synthesis and characterization of a \u201cturn-on\u201d photoCORM for trackable CO delivery to biological targets","volume":"5","author":"Carrington","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.addr.2021.02.005_b0540","doi-asserted-by":"crossref","first-page":"6801","DOI":"10.1039\/C5DT04849D","article-title":"PhotoCORMs: CO release moves into the visible","volume":"45","author":"Wright","year":"2016","journal-title":"Dalton Trans."},{"key":"10.1016\/j.addr.2021.02.005_b0545","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1002\/anie.201006598","article-title":"Acyloxybutadiene iron tricarbonyl complexes as enzyme-triggered CO-releasing molecules (ET-CORMs)","volume":"50","author":"Romanski","year":"2011","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.addr.2021.02.005_b0550","doi-asserted-by":"crossref","first-page":"31158","DOI":"10.1021\/acsami.8b11758","article-title":"Coordination modulation method to prepare new metal-organic framework-based CO-releasing materials","volume":"10","author":"Carmona","year":"2018","journal-title":"ACS Appl. Mater. 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Sci."},{"key":"10.1016\/j.addr.2021.02.005_b0580","doi-asserted-by":"crossref","first-page":"5557","DOI":"10.1039\/C7CC01576C","article-title":"Intratumoral H2O2-triggered release of CO from a metal carbonyl-based nanomedicine for efficient CO therapy","volume":"53","author":"Jin","year":"2017","journal-title":"Chem. 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Sci."},{"key":"10.1016\/j.addr.2021.02.005_b0695","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1039\/C5AN02208H","article-title":"Electrochemical hydrogen sulfide biosensors","volume":"141","author":"Xu","year":"2016","journal-title":"Analyst"},{"key":"10.1016\/j.addr.2021.02.005_b0700","series-title":"Methods for the Detection of Gasotransmitters, Gasotransmitters: Physiology and Pathophysiology","first-page":"99","author":"Peng","year":"2012"},{"key":"10.1016\/j.addr.2021.02.005_b0705","doi-asserted-by":"crossref","first-page":"11551","DOI":"10.1021\/acs.chemrev.8b00797","article-title":"Electrochemical nitric oxide sensors: principles of design and characterization","volume":"119","author":"Brown","year":"2019","journal-title":"Chem. 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