{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:40:02Z","timestamp":1790278802301,"version":"4.1.0"},"reference-count":292,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFE0201700"],"award-info":[{"award-number":["2020YFE0201700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018617","name":"Liaoning Revitalization Talents Program","doi-asserted-by":"publisher","award":["XLYC1908031"],"award-info":[{"award-number":["XLYC1908031"]}],"id":[{"id":"10.13039\/501100018617","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81673378"],"award-info":[{"award-number":["81673378"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204298"],"award-info":[{"award-number":["82204298"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advanced Drug Delivery Reviews"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.addr.2023.115044","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T03:20:20Z","timestamp":1690946420000},"page":"115044","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":116,"special_numbering":"C","title":["The interplay between PEGylated nanoparticles and blood immune system"],"prefix":"10.1016","volume":"200","author":[{"given":"Chen","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyang","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibing","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxin","family":"Gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.addr.2023.115044_b0005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.addr.2020.07.024","article-title":"Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals","volume":"154\u2013155","author":"Kozma","year":"2020","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.114079","article-title":"To PEGylate or not to PEGylate: Immunological properties of nanomedicine\u2019s most popular component, polyethylene glycol and its alternatives","volume":"180","author":"Shi","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b0015","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.addr.2015.09.012","article-title":"PEGylation as a strategy for improving nanoparticle-based drug and gene delivery","volume":"99","author":"Suk","year":"2016","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b0020","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jconrel.2016.06.040","article-title":"Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation","volume":"244","author":"Zhang","year":"2016","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0025","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1248\/bpb.b13-00107","article-title":"Anti-polyethyleneglycol Antibody Response to PEGylated Substances","volume":"36","author":"Ishida","year":"2013","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.addr.2023.115044_b0030","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.ejpb.2015.03.033","article-title":"Design attributes of long-circulating polymeric drug delivery vehicles","volume":"97","author":"Beck-Broichsitter","year":"2015","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"24","key":"10.1016\/j.addr.2023.115044_b0035","doi-asserted-by":"crossref","first-page":"10748","DOI":"10.1039\/D1NR02065J","article-title":"Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery","volume":"13","author":"Shi","year":"2021","journal-title":"Nanoscale"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0040","doi-asserted-by":"crossref","DOI":"10.1208\/s12249-022-02308-7","article-title":"Chitosan-Coated Liposomes: The Strategy to Reduce Intestinal Toxicity and Improve Bioavailability of Oral Vinorelbine","volume":"23","author":"Guo","year":"2022","journal-title":"AAPS PharmSciTech"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0045","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s11095-022-03174-5","article-title":"Improved Core Viscosity Achieved by PDLLA(10k)Co-Incorporation Promoted Drug Loading and Stability of mPEG(2k)-b-PDLLA(2.4k) Micelles","volume":"39","author":"Guo","year":"2022","journal-title":"Pharm Res."},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0050","doi-asserted-by":"crossref","first-page":"14022","DOI":"10.1021\/acsnano.1c05922","article-title":"Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies","volume":"15","author":"Chen","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2023.115044_b0055","doi-asserted-by":"crossref","unstructured":"\u6e05\u6c34 \u592a, \u7570\u5cf6 \u512a, \u77f3\u7530 \u7adc. \u30bf\u30f3\u30d1\u30af\u306ePEG\u4fee\u98fe\u306b\u3088\u308b\u6297PEG\u514d\u75ab\u5fdc\u7b54\u306e\u8a98\u5c0e. YAKUGAKU ZASSHI. 2020;140(2):163\u2013169. doi: https:\/\/doi.org\/10.1248\/yakushi.19-00187-5.","DOI":"10.1248\/yakushi.19-00187-5"},{"key":"10.1016\/j.addr.2023.115044_b0060","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2022.882363","article-title":"Understanding the Role and Impact of Poly (Ethylene Glycol) (PEG) on Nanoparticle Formulation: Implications for COVID-19 Vaccines","volume":"10","author":"Padin-Gonzalez","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0065","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10071641","article-title":"Immune Response in Regard to Hypersensitivity Reactions after COVID-19 Vaccination","volume":"10","author":"Hsieh","year":"2022","journal-title":"Biomedicines."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0070","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jconrel.2013.07.026","article-title":"The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage","volume":"172","author":"Abu Lila","year":"2013","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0075","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1080\/14686996.2019.1590126","article-title":"Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review","volume":"20","author":"Shiraishi","year":"2019","journal-title":"Sci. Technol. Adv. Mater."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b0080","doi-asserted-by":"crossref","first-page":"9315","DOI":"10.1021\/acsnano.9b03942","article-title":"Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions","volume":"13","author":"Kozma","year":"2019","journal-title":"ACS Nano"},{"issue":"15","key":"10.1016\/j.addr.2023.115044_b0085","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/j.addr.2012.07.005","article-title":"A porcine model of complement-mediated infusion reactions to drug carrier nanosystems and other medicines","volume":"64","author":"Szebeni","year":"2012","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0090","article-title":"Immunogenicity of Polyethylene Glycol Based Nanomedicines: Mechanisms","volume":"3","author":"D'Avanzo","year":"2020","journal-title":"Clinical Implications and Systematic Approach. Advanced Therapeutics."},{"key":"10.1016\/j.addr.2023.115044_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2019.112669","article-title":"A generic method for the detection of polyethylene glycol specific IgG and IgM antibodies in human serum","volume":"474","author":"Ehlinger","year":"2019","journal-title":"J. Immunol. Methods"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0100","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s40883-021-00198-y","article-title":"Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies","volume":"8","author":"Freire Haddad","year":"2022","journal-title":"Regener. Eng. Transl. Med."},{"key":"10.1016\/j.addr.2023.115044_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114463","article-title":"The in vivo fate of polymeric micelles","volume":"188","author":"Cai","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0110","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/wnan.1339","article-title":"Anti-PEG immunity: emergence, characteristics, and unaddressed questions","volume":"7","author":"Yang","year":"2015","journal-title":"Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology."},{"key":"10.1016\/j.addr.2023.115044_b0115","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jconrel.2021.12.033","article-title":"Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists","volume":"342","author":"Stavnsbjerg","year":"2022","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0120","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1080\/14686996.2019.1627174","article-title":"PEGylated liposomes: immunological responses","volume":"20","author":"Mohamed","year":"2019","journal-title":"Sci. Technol. Adv. Mater."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b0125","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.addr.2011.06.017","article-title":"Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: Prediction and prevention","volume":"63","author":"Szebeni","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b0130","doi-asserted-by":"crossref","unstructured":"\u5c0f\u51fa \u88d5, \u6d45\u4e95 \u77e5, \u7551\u4e2d \u5263, \u6e05\u6c34 \u5e83, \u6a2a\u5c71 \u660c, \u77f3\u7530 \u7adc, et al. PEG\u5316\u30ca\u30ce\u30ad\u30e3\u30ea\u30a2\u983b\u56de\u6295\u4e0e\u306b\u3088\u308baccelerated blood clearance\u73fe\u8c61\u306e\u6a5f\u69cb\u89e3\u660e. YAKUGAKU ZASSHI. 2009;129(12):1445\u20131451. doi: https:\/\/doi.org\/10.1248\/yakushi.129.1445.","DOI":"10.1248\/yakushi.129.1445"},{"key":"10.1016\/j.addr.2023.115044_b0135","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jconrel.2014.07.010","article-title":"Suppression in mice of immunosurveillance against PEGylated liposomes by encapsulated doxorubicin","volume":"192","author":"Yahuafai","year":"2014","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0140","doi-asserted-by":"crossref","first-page":"5069","DOI":"10.1002\/jps.22682","article-title":"Differences in Colloidal Structure of PEGylated Nanomaterials Dictate the Likelihood of Accelerated Blood Clearance","volume":"100","author":"Kaminskas","year":"2011","journal-title":"J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0145","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.cell.2020.02.001","article-title":"Targeting Strategies for Tissue-Specific Drug Delivery","volume":"181","author":"Zhao","year":"2020","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0150","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41573-020-0090-8","article-title":"Engineering precision nanoparticles for drug delivery","volume":"20","author":"Mitchell","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.addr.2023.115044_b0155","doi-asserted-by":"crossref","unstructured":"S.I. Jenkins D. Weinberg al-Shakli AF, Fernandes AR, Yiu HHP, Telling ND, et al. \u2018Stealth\u2019 nanoparticles evade neural immune cells but also evade major brain cell populations: Implications for PEG-based neurotherapeutics J. Control. Release 224 2016 136 145 10.1016\/j.jconrel.2016.01.013.","DOI":"10.1016\/j.jconrel.2016.01.013"},{"key":"10.1016\/j.addr.2023.115044_b0160","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.addr.2014.05.014","article-title":"Carrier interactions with the biological barriers of the lung: Advanced in vitro models and challenges for pulmonary drug delivery","volume":"75","author":"de Souza","year":"2014","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0165","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1242\/bio.020362","article-title":"Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability","volume":"5","author":"Wilkinson","year":"2016","journal-title":"Biology Open."},{"key":"10.1016\/j.addr.2023.115044_b0170","series-title":"Control and Regulation of Transport Phenomena in the Cardiac System","first-page":"134","article-title":"Regulation of endothelial junctional permeability","author":"Vandenbroucke","year":"2008"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0175","doi-asserted-by":"crossref","first-page":"5785","DOI":"10.1021\/acsnano.9b01383","article-title":"Elimination Pathways of Nanoparticles","volume":"13","author":"Poon","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2023.115044_b0180","first-page":"481","article-title":"Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective","volume":"Vol 52","author":"Moghimi","year":"2012"},{"key":"10.1016\/j.addr.2023.115044_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1029085","article-title":"Resident macrophages of the lung and liver: The guardians of our tissues","volume":"13","author":"Kulle","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.addr.2023.115044_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114238","article-title":"Why nanoparticles prefer liver macrophage cell uptake in vivo","volume":"185","author":"Ngo","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0195","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/j.nano.2016.01.013","article-title":"Cellular distribution of injected PLGA-nanoparticles in the liver","volume":"12","author":"Park","year":"2016","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0200","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1038\/nmat4718","article-title":"Mechanism of hard-nanomaterial clearance by the liver","volume":"15","author":"Tsoi","year":"2016","journal-title":"Nat. Mater."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0205","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1021\/ja2084338","article-title":"Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake","volume":"134","author":"Walkey","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0210","doi-asserted-by":"crossref","first-page":"13739","DOI":"10.1021\/acsnano.0c06033","article-title":"Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting","volume":"14","author":"Sivaram","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2023.115044_b0215","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jconrel.2016.01.020","article-title":"Nanoparticle\u2013liver interactions: Cellular uptake and hepatobiliary elimination","volume":"240","author":"Zhang","year":"2016","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0220","article-title":"Understanding Nanomaterial-Liver Interactions to Facilitate the Development of Safer Nanoapplications","volume":"34","author":"Li","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.addr.2023.115044_b0225","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.ijpharm.2019.01.056","article-title":"Advances in nanocarriers enabled brain targeted drug delivery across blood brain barrier","volume":"559","author":"Sharma","year":"2019","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.addr.2023.115044_b0230","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jconrel.2017.12.015","article-title":"Crossing the blood-brain barrier with nanoparticles","volume":"270","author":"Zhou","year":"2018","journal-title":"J. Control. Release"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0235","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.apsb.2016.05.013","article-title":"Progress and perspectives on targeting nanoparticles for brain drug delivery","volume":"6","author":"Gao","year":"2016","journal-title":"Acta Pharm. Sin. B"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0240","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.apsb.2017.12.002","article-title":"Biomimetic nanoparticles for inflammation targeting","volume":"8","author":"Jin","year":"2018","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.addr.2023.115044_b0245","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.toxlet.2022.01.011","article-title":"Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats","volume":"359","author":"Fang","year":"2022","journal-title":"Toxicol. Lett."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0250","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ejps.2005.08.002","article-title":"In vivo tumor targeting of tumor necrosis factor-\u03b1-loaded stealth nanoparticles: Effect of MePEG molecular weight and particle size","volume":"27","author":"Fang","year":"2006","journal-title":"Eur J Pharm Sci."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0255","doi-asserted-by":"crossref","first-page":"5554","DOI":"10.3390\/ijms13055554","article-title":"Dextran and Polymer Polyethylene Glycol (PEG) Coating Reduce Both 5 and 30 nm Iron Oxide Nanoparticle Cytotoxicity in 2D and 3D Cell Culture","volume":"13","author":"Yu","year":"2012","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0260","article-title":"PEGylation of Metal Oxide Nanoparticles Modulates Neutrophil Extracellular Trap Formation","volume":"12","author":"Snoderly","year":"2022","journal-title":"Biosensors-Basel."},{"key":"10.1016\/j.addr.2023.115044_b0265","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.smim.2017.10.001","article-title":"Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System","volume":"34","author":"Barbero","year":"2017","journal-title":"Semin. Immunol."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0270","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-16772-x","article-title":"Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface","volume":"11","author":"Abbina","year":"2020","journal-title":"Nat Commun."},{"key":"10.1016\/j.addr.2023.115044_b0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114356","article-title":"The effects of protein corona on in vivo fate of nanocarriers","volume":"186","author":"Xiao","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b0280","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.actbio.2021.05.019","article-title":"The protein corona and its effects on nanoparticle-based drug delivery systems","volume":"129","author":"Li","year":"2021","journal-title":"Acta Biomater."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0285","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/nnano.2015.330","article-title":"Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers","volume":"11","author":"Sch\u00f6ttler","year":"2016","journal-title":"Nat. Nanotechnol."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0290","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1021\/ja309812z","article-title":"Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency","volume":"135","author":"Lesniak","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.addr.2023.115044_b0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.117013","article-title":"Low density lipoprotein receptor (LDLR)-targeted lipid nanoparticles for the delivery of sorafenib and Dihydroartemisinin in liver cancers","volume":"239","author":"Wang","year":"2019","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032568","article-title":"Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model","volume":"7","author":"Wagner","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0305","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nnano.2016.269","article-title":"Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo","volume":"12","author":"Chen","year":"2017","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.addr.2023.115044_b0310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2015.07.048","article-title":"Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo","volume":"69","author":"Du","year":"2015","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0315","doi-asserted-by":"crossref","first-page":"10025","DOI":"10.1021\/acsnano.1c01642","article-title":"Influence of Poly(ethylene glycol) Molecular Architecture on Particle Assembly and Ex Vivo Particle-Immune Cell Interactions in Human Blood","volume":"15","author":"Song","year":"2021","journal-title":"ACS Nano"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0320","doi-asserted-by":"crossref","DOI":"10.1002\/wnan.1615","article-title":"Impact of the protein corona on nanomaterial immune response and targeting ability","volume":"12","author":"Digiacomo","year":"2020","journal-title":"Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology."},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0325","doi-asserted-by":"crossref","first-page":"15723","DOI":"10.1021\/acsnano.0c06679","article-title":"Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood","volume":"14","author":"Ju","year":"2020","journal-title":"ACS Nano"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0330","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s00204-016-1797-5","article-title":"Protein bio-corona: critical issue in immune nanotoxicology","volume":"91","author":"Neagu","year":"2017","journal-title":"Arch. Toxicol."},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0335","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1248\/bpb.b20-00345","article-title":"Pegfilgrastim (PEG-G-CSF) Induces Anti-polyethylene Glycol (PEG) IgM <i>via<\/i> a T Cell-Dependent Mechanism","volume":"43","author":"Elsadek","year":"2020","journal-title":"Biol. Pharm. Bull."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0340","doi-asserted-by":"crossref","first-page":"282","DOI":"10.4049\/immunohorizons.1900029","article-title":"Accelerated Blood Clearance of Lipid Nanoparticles Entails a Biphasic Humoral Response of B-1 Followed by B-2 Lymphocytes to Distinct Antigenic Moieties","volume":"3","author":"Besin","year":"2019","journal-title":"ImmunoHorizons."},{"key":"10.1016\/j.addr.2023.115044_b0345","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jconrel.2020.10.033","article-title":"Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes","volume":"329","author":"Shimizu","year":"2021","journal-title":"J. Control. Release"},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0350","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.imbio.2015.06.005","article-title":"Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells","volume":"220","author":"Shimizu","year":"2015","journal-title":"Immunobiology"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0355","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.imbio.2012.08.274","article-title":"Transport of PEGylated liposomes from the splenic marginal zone to the follicle in the induction phase of the accelerated blood clearance phenomenon","volume":"218","author":"Shimizu","year":"2013","journal-title":"Immunobiology"},{"key":"10.1016\/j.addr.2023.115044_b0360","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jconrel.2020.04.011","article-title":"Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon","volume":"323","author":"El Sayed","year":"2020","journal-title":"J. Control. Release"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0365","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1021\/acs.molpharmaceut.1c00255","article-title":"Incorporating Gangliosides into PEGylated Cationic Liposomes that Complexed DNA Attenuates Anti-PEG Antibody Production but Not Anti-DNA Antibody Production in Mice","volume":"18","author":"Qelliny","year":"2021","journal-title":"Mol. Pharm."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0370","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2567.2004.01775.x","article-title":"T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens","volume":"111","author":"Jeurissen","year":"2004","journal-title":"Immunology"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0375","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.4049\/jimmunol.1502282","article-title":"Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21","volume":"197","author":"Prokopec","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.addr.2023.115044_b0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.120529","article-title":"Nucleic acids delivered by PEGylated cationic liposomes in systemic lupus erythematosus-prone mice: A possible exacerbation of lupus nephritis in the presence of pre-existing anti-nucleic acid antibodies","volume":"601","author":"Takata","year":"2021","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.addr.2023.115044_b0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2014.04.003","article-title":"B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice","volume":"184","author":"Hashimoto","year":"2014","journal-title":"J. Control. Release"},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0390","doi-asserted-by":"crossref","first-page":"3755","DOI":"10.1021\/acs.molpharmaceut.8b00019","article-title":"Enhanced Opsonization-Independent Phagocytosis and High Response Ability to Opsonized Antigen-Antibody Complexes: A New Role of Kupffer Cells in the Accelerated Blood Clearance Phenomenon upon Repeated Injection of PEGylated Emulsions","volume":"15","author":"Cheng","year":"2018","journal-title":"Mol. Pharm."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0395","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1021\/acs.molpharmaceut.8b00042","article-title":"Use of Dual-Ligand Modification in Kupffer Cell-Targeted Liposomes To Examine the Contribution of Kupffer Cells to Accelerated Blood Clearance Phenomenon","volume":"15","author":"Lai","year":"2018","journal-title":"Mol. Pharm."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0400","first-page":"455","article-title":"Effect of Kupffer cells depletion on ABC phenomenon induced by Kupffer cells-targeted liposomes","volume":"14","author":"Lai","year":"2019","journal-title":"Asian J. Pharm. Sci."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0405","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.ejpb.2012.04.023","article-title":"A frustrating problem: Accelerated blood clearance of PEGylated solid lipid nanoparticles following subcutaneous injection in rats","volume":"81","author":"Zhao","year":"2012","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0410","doi-asserted-by":"crossref","first-page":"3210","DOI":"10.1208\/s12249-018-1120-2","article-title":"Evaluating the Accelerated Blood Clearance Phenomenon of PEGylated Nanoemulsions in Rats by Intraperitoneal Administration","volume":"19","author":"Su","year":"2018","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.addr.2023.115044_b0415","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.jconrel.2022.12.005","article-title":"The mechanisms of anti-PEG immune response are different in the spleen and the lymph nodes","volume":"353","author":"Grenier","year":"2023","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0420","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14112470","article-title":"Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics","volume":"14","author":"Plant-Hately","year":"2022","journal-title":"Pharmaceutics."},{"issue":"23","key":"10.1016\/j.addr.2023.115044_b0425","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232314592","article-title":"Basophil Activation Test with Different Polyethylene Glycols in Patients with Suspected PEG Hypersensitivity Reactions","volume":"23","author":"Vespa","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0430","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaci.2021.04.032","article-title":"Basophil reactivity to BNT162b2 is mediated by PEGylated lipid nanoparticles in patients with PEG allergy","volume":"148","author":"Troelnikov","year":"2021","journal-title":"J. Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0435","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1111\/all.15187","article-title":"The form of PEG matters: PEG conjugated with lipids and not PEG alone could be the specific form involved in allergic reactions to COVID-19 vaccines","volume":"77","author":"Cabanillas","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.addr.2023.115044_b0440","article-title":"Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress","volume":"493(7434):684-+","author":"Arnon","year":"2013","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0445","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jconrel.2007.11.009","article-title":"The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats","volume":"126","author":"Ishida","year":"2008","journal-title":"J. Control. Release"},{"key":"10.1016\/j.addr.2023.115044_b0450","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jconrel.2021.11.042","article-title":"Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement","volume":"341","author":"Estap\u00e9 Senti","year":"2022","journal-title":"J. Control. Release"},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b0455","first-page":"785","article-title":"Activation of Pregnane X Receptor-Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes","volume":"47","author":"Wang","year":"2019","journal-title":"In Vivo"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0460","first-page":"364","article-title":"Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes","volume":"47","author":"Wang","year":"2019","journal-title":"In Vivo"},{"key":"10.1016\/j.addr.2023.115044_b0465","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jconrel.2018.08.022","article-title":"Anti-polyethylene glycol antibodies alter the protein corona deposited on nanoparticles and the physiological pathways regulating their fate in vivo","volume":"287","author":"Grenier","year":"2018","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0470","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.molimm.2008.08.276","article-title":"Poly(ethylene glycol)s generate complement activation products in human serum through increased alternative pathway turnover and a MASP-2-dependent process","volume":"46","author":"Hamad","year":"2008","journal-title":"Mol. Immunol."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0475","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.tox.2005.07.023","article-title":"Complement activation-related pseudoallergy: A new class of drug-induced acute immune toxicity","volume":"216","author":"Szebeni","year":"2005","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0480","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.molimm.2014.06.038","article-title":"Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals","volume":"61","author":"Szebeni","year":"2014","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.addr.2023.115044_b0485","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.nano.2019.02.002","article-title":"Nanoparticle physicochemical properties determine the activation of intracellular complement","volume":"17","author":"Ilinskaya","year":"2019","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.addr.2023.115044_b0490","first-page":"10","article-title":"Allergic Reactions After the Administration of COVID-19 Vaccines. Frontiers","author":"Bian","year":"2022","journal-title":"Public Health"},{"key":"10.1016\/j.addr.2023.115044_b0495","article-title":"Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines","author":"Chen","year":"2023","journal-title":"ACS Nano"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0500","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.immuni.2013.10.010","article-title":"The Spleen in Local and Systemic Regulation of Immunity","volume":"39","author":"Bronte","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.addr.2023.115044_b0505","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aau6085","article-title":"Structure and function of the immune system in the spleen","author":"Lewis","year":"20194336085","journal-title":"Sci. Immunol."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0510","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s13346-016-0304-0","article-title":"Nanocarriers for spleen targeting: anatomo-physiological considerations, formulation strategies and therapeutic potential","volume":"6","author":"Jindal","year":"2016","journal-title":"Drug Deliv. Transl. Res."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0515","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.jconrel.2006.08.001","article-title":"Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes","volume":"115","author":"Ishida","year":"2006","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0520","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1248\/yakushi.128.233","volume":"128","year":"2008","journal-title":"Yakugaku Zasshi"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0525","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/bab.1291","article-title":"Comprehensive analysis of PEGylated liposome-associated proteins relating to the accelerated blood clearance phenomenon by combination with shotgun analysis and conventional methods","volume":"62","author":"Kawanishi","year":"2015","journal-title":"Biotechnol. Appl. Biochem."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0530","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1248\/bpb.b14-00653","article-title":"Relationship between the Concentration of Anti-polyethylene Glycol (PEG) Immunoglobulin M (IgM) and the Intensity of the Accelerated Blood Clearance (ABC) Phenomenon against PEGylated Liposomes in Mice","volume":"38","author":"Hashimoto","year":"2015","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.addr.2023.115044_b0535","doi-asserted-by":"crossref","unstructured":"L. D\u00e9zsi, T. M\u00e9sz\u00e1ros, G. Kozma, H-Velkei, M, Ol\u00e1h, CZ, Szab\u00f3 M, et al. A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor, GeroScience. 44 (2) (2022) 597\u2013618 10.1007\/s11357-021-00495-y.","DOI":"10.1007\/s11357-021-00495-y"},{"key":"10.1016\/j.addr.2023.115044_b0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.121365","article-title":"Evasion of the accelerated blood clearance phenomenon by branched PEG lipid derivative coating of nanoemulsions","volume":"612","author":"Liu","year":"2022","journal-title":"Int. J. Pharm."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b0545","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1208\/s12249-020-01838-2","article-title":"The Contribution of PEG Molecular Weights in PEGylated Emulsions to the Various Phases in the Accelerated Blood Clearance (ABC) Phenomenon in Rats","volume":"21","author":"Jiao","year":"2020","journal-title":"AAPS PharmSciTech"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0550","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.jconrel.2005.04.003","article-title":"Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes","volume":"105","author":"Ishida","year":"2005","journal-title":"J. Control. Release"},{"issue":"23","key":"10.1016\/j.addr.2023.115044_b0555","doi-asserted-by":"crossref","first-page":"11804","DOI":"10.1021\/acs.analchem.6b03437","article-title":"Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population","volume":"88","author":"Yang","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.addr.2023.115044_b0560","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jconrel.2019.08.017","article-title":"Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG","volume":"311\u2013312","author":"McSweeney","year":"2019","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0565","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ymthe.2005.09.014","article-title":"Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes","volume":"13","author":"Judge","year":"2006","journal-title":"Mol. Ther."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0570","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1002\/jps.23254","article-title":"Accelerated Blood Clearance of Pegylated Liposomal Topotecan: Influence of Polyethylene Glycol Grafting Density and Animal Species","volume":"101","author":"Li","year":"2012","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.addr.2023.115044_b0575","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jconrel.2020.10.011","article-title":"Pre-treatment with high molecular weight free PEG effectively suppresses anti-PEG antibody induction by PEG-liposomes in mice","volume":"329","author":"McSweeney","year":"2021","journal-title":"J. Control. Release"},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0580","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1021\/bm100754e","article-title":"Evasion of the Accelerated Blood Clearance Phenomenon by Coating of Nanoparticles with Various Hydrophilic Polymers","volume":"11","author":"Ishihara","year":"2010","journal-title":"Biomacromolecules"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0585","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.chom.2011.04.006","article-title":"Trained Immunity: A Memory for Innate Host Defense","volume":"9","author":"Netea Mihai","year":"2011","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.addr.2023.115044_b0590","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.jconrel.2021.12.025","article-title":"A preliminary study of the innate immune memory of Kupffer cells induced by PEGylated nanoemulsions","volume":"343","author":"Liu","year":"2022","journal-title":"J. Control. Release"},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0595","doi-asserted-by":"crossref","DOI":"10.3390\/vaccines9090974","article-title":"Pseudo-Anaphylactic Reactions to Pfizer BNT162b2 Vaccine: Report of 3 Cases of Anaphylaxis Post Pfizer BNT162b2 Vaccination","volume":"9","author":"Lim","year":"2021","journal-title":"Vaccines."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0600","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1111\/all.15278","article-title":"Do basophil activation tests help elucidate allergic reactions to the ingredients in COVID-19 vaccines?","volume":"77","author":"Eberlein","year":"2022","journal-title":"Allergy"},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0605","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1111\/all.15148","article-title":"The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine","volume":"77","author":"Labella","year":"2022","journal-title":"Allergy"},{"key":"10.1016\/j.addr.2023.115044_b0610","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ejpb.2021.04.004","article-title":"Application of solid lipid nanoparticles as a long-term drug delivery platform for intramuscular and subcutaneous administration: In vitro and in vivo evaluation","volume":"163","author":"Elbrink","year":"2021","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0615","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s00280-015-2737-4","article-title":"A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax\u00ae) in patients with peritoneal malignancies","volume":"75","author":"Williamson","year":"2015","journal-title":"Cancer Chemother. Pharmacol."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0620","doi-asserted-by":"crossref","first-page":"7226","DOI":"10.1021\/acs.nanolett.9b02834","article-title":"Nanoparticle Size Influences Antigen Retention and Presentation in Lymph Node Follicles for Humoral Immunity","volume":"19","author":"Zhang","year":"2019","journal-title":"Nano Lett."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0625","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.addr.2011.05.018","article-title":"The role of the lymphatic system in vaccine trafficking and immune response","volume":"63","author":"Pal","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0630","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s40820-023-01125-2","article-title":"Application of Nano-Delivery Systems in Lymph Nodes for Tumor Immunotherapy","volume":"15","author":"Xia","year":"2023","journal-title":"Nano-Micro Letters."},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b0635","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1586\/14760584.2014.936852","article-title":"Oral delivery of nanoparticle-based vaccines","volume":"13","author":"Marasini","year":"2014","journal-title":"Expert Rev. Vaccines"},{"key":"10.1016\/j.addr.2023.115044_b0640","doi-asserted-by":"crossref","first-page":"S1102","DOI":"10.1080\/21691401.2018.1533842","article-title":"Recent advancement in nanocarriers for oral vaccination","volume":"46","author":"Kour","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0645","first-page":"948","article-title":"Oral Vaccine Delivery for Intestinal Immunity\u2014Biological Basis, Barriers","volume":"10","author":"Kang","year":"2018","journal-title":"Delivery System, and M Cell Targeting."},{"key":"10.1016\/j.addr.2023.115044_b0650","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.addr.2017.04.008","article-title":"Current state and challenges in developing oral vaccines","volume":"114","author":"Vela Ramirez","year":"2017","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0655","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s40005-021-00537-9","article-title":"Recent advances in nano\/microparticle-based oral vaccines","volume":"51","author":"Li","year":"2021","journal-title":"J. Pharm. Investig."},{"issue":"19","key":"10.1016\/j.addr.2023.115044_b0660","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1016\/j.vaccine.2021.03.073","article-title":"Anaphylactic reactions to mRNA COVID-19 vaccines: A call for further study","volume":"39","author":"Hatziantoniou","year":"2021","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0665","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1111\/all.14711","article-title":"Allergic reactions to the first COVID-19 vaccine: A potential role of polyethylene glycol?","volume":"76","author":"Cabanillas","year":"2021","journal-title":"Allergy"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0670","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.vaccine.2020.12.084","article-title":"Anaphylactic reactions to novel mRNA SARS-CoV-2\/COVID-19 vaccines","volume":"39","author":"Kelso","year":"2021","journal-title":"Vaccine"},{"key":"10.1016\/j.addr.2023.115044_b0675","doi-asserted-by":"crossref","DOI":"10.1007\/s40264-023-01277-5","article-title":"Is PEGylation of Drugs Associated with Hypersensitivity Reactions? An Analysis of the Italian National Spontaneous Adverse Drug Reaction Reporting System","author":"Crisafulli","year":"2023","journal-title":"Drug Saf."},{"key":"10.1016\/j.addr.2023.115044_b0680","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jconrel.2014.08.009","article-title":"Features of complement activation-related pseudoallergy to liposomes with different surface charge and PEGylation: Comparison of the porcine and rat responses","volume":"195","author":"D\u00e9zsi","year":"2014","journal-title":"J. Control. Release"},{"key":"10.1016\/j.addr.2023.115044_b0685","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.00811","article-title":"Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools","volume":"10","author":"Ben Mkaddem","year":"2019","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0690","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.25524","article-title":"Assessment of Allergic and Anaphylactic Reactions to mRNA COVID-19 Vaccines With Confirmatory Testing in a US Regional Health System","volume":"4","author":"Warren","year":"2021","journal-title":"JAMA Netw. Open"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0695","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.alit.2022.05.007","article-title":"Serum polyethylene glycol-specific IgE and IgG in patients with hypersensitivity to COVID-19 mRNA vaccines","volume":"71","author":"Mouri","year":"2022","journal-title":"Allergol. Int."},{"key":"10.1016\/j.addr.2023.115044_b0700","doi-asserted-by":"crossref","unstructured":"Zhou Z-H, Stone CA, Jakubovic B, Phillips EJ, Sussman G, Park J, et al. Anti-PEG IgE in anaphylaxis associated with polyethylene glycol. The Journal of Allergy and Clinical Immunology: In Practice. 2021;9(4):1731-3.e3. doi: https:\/\/doi.org\/10.1016\/j.jaip.2020.11.011.","DOI":"10.1016\/j.jaip.2020.11.011"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0705","first-page":"250","article-title":"Effects of complement inhibition on the ABC phenomenon in rats","volume":"12","author":"Wang","year":"2017","journal-title":"Asian J. Pharm. Sci."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0710","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jconrel.2006.08.017","article-title":"Accelerated blood clearance of PEGylated liposomes upon repeated injections: Effect of doxorubicin-encapsulation and high-dose first injection","volume":"115","author":"Ishida","year":"2006","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0715","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jconrel.2012.02.029","article-title":"Prevention of infusion reactions to PEGylated liposomal doxorubicin via tachyphylaxis induction by placebo vesicles: A porcine model","volume":"160","author":"Szebeni","year":"2012","journal-title":"J. Control. Release"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0720","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.nano.2015.12.377","article-title":"Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model","volume":"12","author":"Jackman","year":"2016","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0725","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1684\/ejd.2017.2986","article-title":"Immediate hypersensitivity reaction to pegylated liposomal doxorubicin: management and outcome in four patients","volume":"27","author":"Ingen-Housz-Oro","year":"2017","journal-title":"Eur. J. Dermatol."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0730","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/1078155207080117","article-title":"Liposomal doxorubicin-associated acute hypersensitivity despite appropriate preventive measures","volume":"13","author":"Chan","year":"2007","journal-title":"J. Oncol. Pharm. practice : official publication of the Int. Soc. Oncol. Pharm. Practitioners."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0735","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ijpharm.2014.09.047","article-title":"Influence of dose and animal species on accelerated blood clearance of PEGylated liposomal doxorubicin","volume":"476","author":"Suzuki","year":"2014","journal-title":"Int. J. Pharm."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0740","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1248\/cpb.c22-00047","article-title":"Development of an Antigen Delivery System for a B Cell-Targeted Vaccine as an Alternative to Dendritic Cell-Targeted Vaccines","volume":"70","author":"Shimizu","year":"2022","journal-title":"Chem. Pharm. Bull."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0745","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201805760","article-title":"Nanomaterial Manipulation of Immune Microenvironment in the Diseased Liver","volume":"29","author":"Hu","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0750","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190723","article-title":"Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets","volume":"217","author":"Deppermann","year":"2020","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b0755","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1038\/s41563-020-0755-z","article-title":"The dose threshold for nanoparticle tumour delivery","volume":"19","author":"Ouyang","year":"2020","journal-title":"Nat. Mater."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0760","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1002\/ijc.27502","article-title":"Effective delivery of chemotherapeutic nanoparticles by depleting host Kupffer cells","volume":"131","author":"Ohara","year":"2012","journal-title":"Int. J. Cancer"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b0765","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3109\/10611860108998772","article-title":"Polylactide-poly(ethylene glycol) micellar-like particles as potential drug carriers: production, colloidal properties and biological performance","volume":"9","author":"Stolnik","year":"2001","journal-title":"J. Drug Target."},{"key":"10.1016\/j.addr.2023.115044_b0770","doi-asserted-by":"crossref","unstructured":"Zapotoczny B, Szafranska K, Owczarczyk K, Kus E, Chlopicki S, Szymonski M. Atomic Force Microscopy Reveals the Dynamic Morphology of Fenestrations in Live Liver Sinusoidal Endothelial Cells. Scientific Reports. 2017;7(1):7994. doi: https:\/\/doi.org10.1038\/s41598-017-08555-0.","DOI":"10.1038\/s41598-017-08555-0"},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b0775","first-page":"1985","volume":"9","author":"Cacicedo","year":"2020","journal-title":"Role of Liver-Mediated Tolerance in Nanoparticle-Based Tumor Therapy."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0780","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ijpharm.2010.03.022","article-title":"T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes","volume":"392","author":"Koide","year":"2010","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.addr.2023.115044_b0785","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jconrel.2020.12.004","article-title":"In vivo blockade of mononuclear phagocyte system with solid nanoparticles: Efficiency and affecting factors","volume":"330","author":"Mirkasymov","year":"2021","journal-title":"J. Control. Release"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0790","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0163-7258(95)02013-6","article-title":"The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity","volume":"68","author":"Park","year":"1995","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0795","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1208\/aapsj080112","article-title":"Cytochrome P450s and other enzymes in drug metabolism and toxicity","volume":"8","author":"Guengerich","year":"2006","journal-title":"AAPS J."},{"key":"10.1016\/j.addr.2023.115044_b0800","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121415","article-title":"Branched PEG-modification: A new strategy for nanocarriers to evade of the accelerated blood clearance phenomenon and enhance anti-tumor efficacy","volume":"283","author":"Liu","year":"2022","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0805","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s13346-018-0588-3","article-title":"Effects of stability of PEGylated micelles on the accelerated blood clearance phenomenon","volume":"9","author":"Su","year":"2019","journal-title":"Drug Deliv. Transl. Res."},{"key":"10.1016\/j.addr.2023.115044_b0810","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jconrel.2016.05.010","article-title":"Exploring the relationship between anti-PEG IgM behaviors and PEGylated nanoparticles and its significance for accelerated blood clearance","volume":"234","author":"Shiraishi","year":"2016","journal-title":"J. Control. Release"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0815","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jconrel.2012.11.016","article-title":"Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon","volume":"165","author":"Shiraishi","year":"2013","journal-title":"J. Control. Release"},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b0820","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1208\/s12249-021-02047-1","article-title":"Evaluation of the Antitumor Effect and Immune Response of Micelles Modified with a Polysialic Acid-d-\u03b1-Tocopheryl Polyethylene Glycol 1000 Succinate Conjugate","volume":"22","author":"Sun","year":"2021","journal-title":"AAPS PharmSciTech"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0825","first-page":"1","volume":"3","author":"Ichihara","year":"2011","journal-title":"Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0830","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.ijpharm.2012.07.049","article-title":"Accelerated blood clearance of PEGylated liposomes containing doxorubicin upon repeated administration to dogs","volume":"436","author":"Suzuki","year":"2012","journal-title":"Int. J. Pharm."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0835","first-page":"28","article-title":"Mixed PEGylated surfactant modifying system decrease the accelerated blood clearance phenomenon of nanoemulsions in rats","volume":"12","author":"Su","year":"2017","journal-title":"Asian J. Pharm. Sci."},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b0840","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00418-022-02086-0","article-title":"A higher dose of PEGylated gold nanoparticles reduces the accelerated blood clearance phenomenon effect and induces spleen B lymphocytes in albino mice","volume":"157","author":"Abu-Dief","year":"2022","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.addr.2023.115044_b0845","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.actbio.2020.11.047","article-title":"Alternating stealth polymer coatings between administrations minimizes toxic and antibody immune responses towards nanomedicine treatment regimens","volume":"121","author":"Li","year":"2021","journal-title":"Acta Biomater."},{"key":"10.1016\/j.addr.2023.115044_b0850","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121676","article-title":"Polyglycerol and Poly(ethylene glycol) exhibit different effects on pharmacokinetics and antibody generation when grafted to nanoparticle surfaces","volume":"287","author":"Shin","year":"2022","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0855","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1007\/s11095-009-9943-x","article-title":"Accelerated Blood Clearance Phenomenon Upon Repeated Injection of PEG-modified PLA-nanoparticles","volume":"26","author":"Ishihara","year":"2009","journal-title":"Pharm. Res."},{"key":"10.1016\/j.addr.2023.115044_b0860","article-title":"A noticeable phenomenon: Thiol terminal PEG enhances the immunogenicity of PEGylated emulsions injected intravenously or subcutaneously into rats","volume":"85(3, Part A):744\u201351","author":"Wang","year":"2013","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0865","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s11095-012-0934-y","article-title":"Accelerated Blood Clearance of PEGylated PLGA Nanoparticles Following Repeated Injections: Effects of Polymer Dose, PEG Coating, and Encapsulated Anticancer Drug","volume":"30","author":"Saadati","year":"2013","journal-title":"Pharm. Res."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0870","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s11095-009-0018-9","article-title":"Accelerated Blood Clearance Was Not Induced for a Gadolinium-Containing PEG-poly(L-lysine)-Based Polymeric Micelle in Mice","volume":"27","author":"Ma","year":"2010","journal-title":"Pharm. Res."},{"key":"10.1016\/j.addr.2023.115044_b0875","doi-asserted-by":"crossref","unstructured":"Jelinek DF. Regulation of B lymphocyte differentiation. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2000;84(4):375-85; quiz 85-7. doi: https:\/\/doi.org\/10.1016\/s1081-1206(10)62267-3.","DOI":"10.1016\/S1081-1206(10)62267-3"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0880","article-title":"Mechanistic basis of co-stimulatory CD40-CD40L ligation mediated regulation of immune responses in cancer and autoimmune disorders","volume":"225","author":"Dakal","year":"2020","journal-title":"Immunobiology"},{"key":"10.1016\/j.addr.2023.115044_b0885","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1034\/j.1600-065X.2000.00607.x","article-title":"B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms","volume":"176","author":"Vos","year":"2000","journal-title":"Immunol. Rev."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0890","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/imr.13070","article-title":"Role of inhibitory signaling in peripheral B cell tolerance","volume":"307","author":"Getahun","year":"2022","journal-title":"Immunol. Rev."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0895","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00109-015-1252-8","article-title":"Signaling mechanisms regulating B-lymphocyte activation and tolerance","volume":"93","author":"Hobeika","year":"2015","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.addr.2023.115044_b0900","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.119792","article-title":"PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: Faster PEG shedding attenuates anti-PEG IgM production","volume":"588","author":"Suzuki","year":"2020","journal-title":"Int. J. Pharm."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b0905","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1208\/s12249-020-1640-4","article-title":"Effects of Uncleavable and Cleavable PEG-Lipids with Different Molecular Weights on Accelerated Blood Clearance of PEGylated Emulsions in Beagle Dogs","volume":"21","author":"Jiao","year":"2020","journal-title":"AAPS PharmSciTech"},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b0910","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1021\/acs.bioconjchem.1c00339","article-title":"Engineering PEGylated Polyester Nanoparticles to Reduce Complement-Mediated Infusion Reaction","volume":"32","author":"Maisha","year":"2021","journal-title":"Bioconjug. Chem."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0915","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s42004-022-00709-0","article-title":"Structural determination of an antibody that specifically recognizes polyethylene glycol with a terminal methoxy group","volume":"5","author":"Nguyen","year":"2022","journal-title":"Commun. Chem."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b0920","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1021\/acsbiomaterials.7b00147","article-title":"Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a C-C-O Backbone","volume":"3","author":"McCallen","year":"2017","journal-title":"ACS Biomater Sci. Eng."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b0925","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201801177","article-title":"Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties","volume":"8","author":"Joh","year":"2019","journal-title":"Adv. Healthc. Mater."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b0930","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/s42004-020-00369-y","article-title":"Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers","volume":"3","author":"Huckaby","year":"2020","journal-title":"Communications Chemistry."},{"key":"10.1016\/j.addr.2023.115044_b0935","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ejpb.2018.02.019","article-title":"A hydroxyl PEG version of PEGylated liposomes and its impact on anti-PEG IgM induction and on the accelerated clearance of PEGylated liposomes","volume":"127","author":"Shimizu","year":"2018","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0940","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.molimm.2013.07.014","article-title":"Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins","volume":"57","author":"Saifer","year":"2014","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.addr.2023.115044_b0945","article-title":"Structural basis of polyethylene glycol recognition by antibody","volume":"27(1):12","author":"Lee","year":"2020","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.addr.2023.115044_b0950","first-page":"2891","article-title":"Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles","volume":"7","author":"Zhao","year":"2012","journal-title":"Int. J. Nanomed."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b0955","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1021\/acs.bioconjchem.7b00793","article-title":"Complement Activation by PEGylated Gold Nanoparticles","volume":"29","author":"Quach","year":"2018","journal-title":"Bioconjug. Chem."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0960","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ejps.2013.03.007","article-title":"Complement activation by PEGylated liposomes containing prednisolone","volume":"49","author":"van den Hoven","year":"2013","journal-title":"Eur. J. Pharm. Sci."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b0965","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.addr.2011.06.002","article-title":"Material properties in complement activation","volume":"63","author":"Moghimi","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b0970","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.nano.2011.06.003","article-title":"Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and Am Bisome","volume":"8","author":"Szebeni","year":"2012","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.addr.2023.115044_b0975","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jconrel.2022.09.031","article-title":"Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products","volume":"351","author":"Ibrahim","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.addr.2023.115044_b0980","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.addr.2019.01.002","article-title":"Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers","volume":"143","author":"Zhao","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b0985","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1016\/j.biomaterials.2007.12.037","article-title":"Particle size-dependent organ distribution of gold nanoparticles after intravenous administration","volume":"29","author":"De Jong","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2023.115044_b0990","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jconrel.2021.03.025","article-title":"Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunability","volume":"333","author":"Vogler","year":"2021","journal-title":"J. Control. Release"},{"issue":"23","key":"10.1016\/j.addr.2023.115044_b0995","doi-asserted-by":"crossref","first-page":"6037","DOI":"10.1016\/j.biomaterials.2014.04.019","article-title":"Improving drug accumulation and photothermal efficacy in tumor depending on size of ICG loaded lipid-polymer nanoparticles","volume":"35","author":"Zhao","year":"2014","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1000","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1021\/mp300684a","article-title":"Size-Dependent Tumor Penetration and in Vivo Efficacy of Monodisperse Drug-Silica Nanoconjugates","volume":"10","author":"Tang","year":"2013","journal-title":"Mol. Pharm."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1005","doi-asserted-by":"crossref","DOI":"10.1002\/app.42884","article-title":"Effect of protein adsorption on cell uptake and blood clearance of methoxy poly(ethylene glycol)-poly(caprolactone) nanoparticles","volume":"133","author":"Li","year":"2016","journal-title":"J. Appl. Polym. Sci."},{"issue":"9\u201310","key":"10.1016\/j.addr.2023.115044_b1010","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1002\/smll.201201390","article-title":"Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking","volume":"9","author":"Duan","year":"2013","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ijpharm.2008.06.004","article-title":"Particle size-dependent triggering of accelerated blood clearance phenomenon","volume":"362","author":"Koide","year":"2008","journal-title":"Int. J. Pharm."},{"issue":"32","key":"10.1016\/j.addr.2023.115044_b1020","doi-asserted-by":"crossref","first-page":"9755","DOI":"10.1021\/acs.langmuir.1c01182","article-title":"Size Dependence Unveiling the Adsorption Interaction of High-Density Lipoprotein Particles with PEGylated Gold Nanoparticles in Biomolecular Corona Formation","volume":"37","author":"Jang","year":"2021","journal-title":"Langmuir"},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b1025","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.4049\/jimmunol.0902214","article-title":"Curvature of Synthetic and Natural Surfaces Is an Important Target Feature in Classical Pathway Complement Activation","volume":"184","author":"Pedersen","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.addr.2023.115044_b1030","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jconrel.2021.09.003","article-title":"Asymmetric polymersomes, from the formation of asymmetric membranes to the application on drug delivery","volume":"338","author":"Guo","year":"2021","journal-title":"J. Control. Release"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b1035","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1021\/acs.chemmater.6b04700","article-title":"Shape Control of Soft Nanoparticles and Their Assemblies","volume":"29","author":"Chen","year":"2017","journal-title":"Chem. Mater."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1040","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1039\/C5NR07681A","article-title":"Shape control of inorganic nanoparticles from solution","volume":"8","author":"Wu","year":"2016","journal-title":"Nanoscale"},{"key":"10.1016\/j.addr.2023.115044_b1045","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2019.109353","article-title":"Role of particle shape on efficient and organ-based drug delivery","volume":"122","author":"Nejati","year":"2020","journal-title":"Eur. Polym. J."},{"key":"10.1016\/j.addr.2023.115044_b1050","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jconrel.2021.12.032","article-title":"Effect of micro- and nanoparticle shape on biological processes","volume":"342","author":"Hadji","year":"2022","journal-title":"J. Control. Release"},{"issue":"30","key":"10.1016\/j.addr.2023.115044_b1055","doi-asserted-by":"crossref","first-page":"7606","DOI":"10.1016\/j.biomaterials.2010.06.051","article-title":"Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods","volume":"31","author":"Qiu","year":"2010","journal-title":"Biomaterials"},{"issue":"43","key":"10.1016\/j.addr.2023.115044_b1060","first-page":"17247","volume":"110","author":"Agarwal","year":"2013","journal-title":"Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1065","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s11095-008-9626-z","article-title":"Shape Induced Inhibition of Phagocytosis of Polymer Particles","volume":"26","author":"Champion","year":"2009","journal-title":"Pharm. Res."},{"key":"10.1016\/j.addr.2023.115044_b1070","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jconrel.2022.04.005","article-title":"Re-directing nanomedicines to the spleen: A potential technology for peripheral immunomodulation","volume":"350","author":"Kaur","year":"2022","journal-title":"J. Control. Release"},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b1075","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1007\/s11051-014-2512-1","article-title":"Gold nanoparticle shape effects on human serum albumin corona interface: a molecular dynamic study","volume":"16","author":"Ramezani","year":"2014","journal-title":"J. Nanopart. Res."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1080","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1039\/C7NR08322J","article-title":"In vivo formation of protein corona on gold nanoparticles. The effect of their size and shape","volume":"10","author":"Garcia-Alvarez","year":"2018","journal-title":"Nanoscale"},{"key":"10.1016\/j.addr.2023.115044_b1085","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.111270","article-title":"The influence of shape and charge on protein corona composition in common gold nanostructures","volume":"117","author":"Bewersdorff","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"issue":"25","key":"10.1016\/j.addr.2023.115044_b1090","article-title":"The Influence of Nanoparticle Shape on Protein Corona Formation","volume":"16","author":"Visalakshan","year":"2020","journal-title":"Small"},{"issue":"22","key":"10.1016\/j.addr.2023.115044_b1095","doi-asserted-by":"crossref","first-page":"6780","DOI":"10.1021\/acs.langmuir.2c01117","article-title":"Modulation of Colloidal Particle Stiffness for the Exploration of Bio-Nano Interactions","volume":"38","author":"Li","year":"2022","journal-title":"Langmuir"},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b1100","doi-asserted-by":"crossref","first-page":"21407","DOI":"10.1021\/acsnano.2c09785","article-title":"Insight into Drug Loading Regulated Micellar Rigidity by Nuclear Magnetic Resonance","volume":"16","author":"Hu","year":"2022","journal-title":"ACS Nano"},{"issue":"24","key":"10.1016\/j.addr.2023.115044_b1105","doi-asserted-by":"crossref","first-page":"16372","DOI":"10.1039\/C7CP08644J","article-title":"Understanding receptor-mediated endocytosis of elastic nanoparticles through coarse grained molecular dynamic simulation","volume":"20","author":"Shen","year":"2018","journal-title":"PCCP"},{"key":"10.1016\/j.addr.2023.115044_b1110","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.addr.2016.01.007","article-title":"Impact of particle elasticity on particle-based drug delivery systems","volume":"108","author":"Anselmo","year":"2017","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b1115","doi-asserted-by":"crossref","first-page":"6681","DOI":"10.1021\/nn301159a","article-title":"Softer Zwitterionic Nanogels for Longer Circulation and Lower Splenic Accumulation","volume":"6","author":"Zhang","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2023.115044_b1120","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.biomaterials.2017.11.031","article-title":"Red blood cell-like particles with the ability to avoid lung and spleen accumulation for the treatment of liver fibrosis","volume":"156","author":"Hayashi","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.addr.2023.115044_b1125","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1016\/j.jcis.2021.08.148","article-title":"Influence of nanoparticle mechanical property on protein corona formation","volume":"606","author":"Tengjisi","year":"2022","journal-title":"J. Colloid Interface Sci."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b1130","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1039\/C9TB02902H","article-title":"Effect of elasticity on the phagocytosis of micro\/nanoparticles","volume":"8","author":"Yao","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.addr.2023.115044_b1135","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jconrel.2016.05.033","article-title":"Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines","volume":"234","author":"Benne","year":"2016","journal-title":"J. Control. Release"},{"issue":"38","key":"10.1016\/j.addr.2023.115044_b1140","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202203070","article-title":"Probing the Effect of Rigidity on the Cellular Uptake of Core-Shell Nanoparticles: Stiffness Effects are Size Dependent","volume":"18","author":"Gurnani","year":"2022","journal-title":"Small"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b1145","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1021\/acsnano.7b07797","article-title":"Modulating Phagocytic Cell Sequestration by Tailoring Nanoconstruct Softness","volume":"12","author":"Palomba","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2023.115044_b1150","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.addr.2019.09.005","article-title":"Physical and chemical profiles of nanoparticles for lymphatic targeting","volume":"151\u2013152","author":"Ke","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1155","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.nano.2015.11.002","article-title":"Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells","volume":"12","author":"Fromen","year":"2016","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.addr.2023.115044_b1160","doi-asserted-by":"crossref","DOI":"10.1016\/j.nano.2020.102244","article-title":"Nanoparticles' properties modify cell type-dependent distribution in immune cells","volume":"29","author":"Youshia","year":"2020","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"44","key":"10.1016\/j.addr.2023.115044_b1165","doi-asserted-by":"crossref","first-page":"5927","DOI":"10.1016\/j.vaccine.2015.07.100","article-title":"Polymeric micro\/nanoparticles: Particle design and potential vaccine delivery applications","volume":"33","author":"Yue","year":"2015","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1170","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1021\/acsabm.8b00220","article-title":"Influence of Charge on Hemocompatibility and Immunoreactivity of Polymeric Nanoparticles","volume":"1","author":"Chen","year":"2018","journal-title":"ACS Applied Bio Materials."},{"key":"10.1016\/j.addr.2023.115044_b1175","doi-asserted-by":"crossref","first-page":"5933","DOI":"10.2147\/IJN.S364381","article-title":"Role of Surface Charge of Nanoscale Ultrasound Contrast Agents in Complement Activation and Phagocytosis","volume":"17","author":"Zhou","year":"2022","journal-title":"Int. J. Nanomed."},{"issue":"38","key":"10.1016\/j.addr.2023.115044_b1180","first-page":"14265","volume":"105","author":"Lundqvist","year":"2008","journal-title":"Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b1185","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.apsb.2021.03.007","article-title":"Effect of physicochemical properties on in vivo fate of nanoparticle-based cancer immunotherapies","volume":"11","author":"Wang","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1190","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1021\/acs.molpharmaceut.9b01182","article-title":"The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution","volume":"17","author":"Nakamura","year":"2020","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.addr.2023.115044_b1195","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.toxlet.2019.02.013","article-title":"Oxidative stress injury in doxorubicin-induced cardiotoxicity","volume":"307","author":"Mei","year":"2019","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.addr.2023.115044_b1200","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.lfs.2018.03.023","article-title":"Toxicity of Doxorubicin (Dox) to different experimental organ systems","volume":"200","author":"Pugazhendhi","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.addr.2023.115044_b1205","first-page":"131","article-title":"Anticancer and cardio-protective effects of liposomal doxorubicin in the treatment of breast cancer","volume":"10","author":"Franco","year":"2018","journal-title":"Breast cancer (Dove Medical Press)."},{"key":"10.1016\/j.addr.2023.115044_b1210","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jconrel.2019.06.007","article-title":"Doxebo (doxorubicin-free Doxil-like liposomes) is safe to use as a pre-treatment to prevent infusion reactions to PEGylated nanodrugs","volume":"306","author":"Bavli","year":"2019","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b1215","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.addr.2012.01.018","article-title":"Stimuli-responsive polymers and nanomaterials for gene delivery and imaging applications","volume":"64","author":"Shim","year":"2012","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.addr.2023.115044_b1220","first-page":"178","article-title":"Nucleic acid delivery for therapeutic applications","author":"Gupta","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"13","key":"10.1016\/j.addr.2023.115044_b1225","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1084\/jem.20151620","article-title":"STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria","volume":"213","author":"Chen","year":"2016","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.addr.2023.115044_b1230","doi-asserted-by":"crossref","first-page":"7779","DOI":"10.4049\/jimmunol.178.12.7779","article-title":"TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses","volume":"178","author":"Genestier","year":"2007","journal-title":"J. Immunol."},{"issue":"7","key":"10.1016\/j.addr.2023.115044_b1235","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1084\/jem.20092695","article-title":"Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response","volume":"207","author":"Swanson","year":"2010","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1240","doi-asserted-by":"crossref","first-page":"442","DOI":"10.4049\/jimmunol.0900870","article-title":"Marginal Zone Precursor B Cells as Cellular Agents for Type I IFN-Promoted Antigen Transport in Autoimmunity","volume":"184","author":"Wang","year":"2010","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b1245","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/art.30231","article-title":"Type I Interferon-Dependent CD86(high) Marginal Zone Precursor B Cells Are Potent T Cell Costimulators in Mice","volume":"63","author":"Wang","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.addr.2023.115044_b1250","doi-asserted-by":"crossref","unstructured":"Risma KA, Edwards KM, Hummell DS, Little FF, Norton AE, Stallings A, et al. Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines. J. Allergy Clin. Immunol. 2021;147(6):2075-82.e2. doi: https:\/\/doi.org\/10.1016\/j.jaci.2021.04.002.","DOI":"10.1016\/j.jaci.2021.04.002"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b1255","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jconrel.2009.10.017","article-title":"CpG motifs in pDNA-sequences increase anti-PEG IgM production induced by PEG-coated pDNA-lipoplexes","volume":"142","author":"Tagami","year":"2010","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b1260","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jconrel.2010.12.013","article-title":"Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA","volume":"151","author":"Tagami","year":"2011","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1265","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/ni1542","article-title":"Follicular shuttling of marginal zone B cells facilitates antigen transport","volume":"9","author":"Cinamon","year":"2008","journal-title":"Nat. Immunol."},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b1270","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.ultrasmedbio.2018.02.006","article-title":"ACCELERATED CLEARANCE OF ULTRASOUND CONTRAST AGENTS CONTAINING POLYETHYLENE GLYCOL IS ASSOCIATED WITH THE GENERATION OF ANTI- POLYETHYLENE GLYCOL ANTIBODIES","volume":"44","author":"Fix","year":"2018","journal-title":"Ultrasound Med. Biol."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1275","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ijpharm.2012.08.030","article-title":"Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: A possible mechanism and the potential for clinical application","volume":"438","author":"Abu Lila","year":"2012","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.addr.2023.115044_b1280","first-page":"3645","article-title":"Tolerance-like innate immunity and spleen injury: a novel discovery via the weekly administrations and consecutive injections of PEGylated emulsions","volume":"9","author":"Wang","year":"2014","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.addr.2023.115044_b1285","doi-asserted-by":"crossref","unstructured":"S. Ghareeb, D. Ragheb, A. El-Sheakh, Ashour M-BA Potential Toxic Effects of Exposure to Titanium Silicon Oxide Nanoparticles in Male Rats. 19 4 2022 2029 10.3390\/ijerph19042029.","DOI":"10.3390\/ijerph19042029"},{"key":"10.1016\/j.addr.2023.115044_b1290","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jconrel.2017.12.023","article-title":"Liposome-induced immunosuppression and tumor growth is mediated by macrophages and mitigated by liposome-encapsulated alendronate","volume":"271","author":"Rajan","year":"2018","journal-title":"J. Control. Release"},{"key":"10.1016\/j.addr.2023.115044_b1295","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.134779","article-title":"Immune modulating nanoparticles depleting tumor-associated macrophages to enhance immune checkpoint blockade therapy","volume":"435","author":"Zheng","year":"2022","journal-title":"Chem. Eng. J."},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b1300","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1539\/joh.16-0184-OA","article-title":"Comparison of single or multiple intratracheal administration for pulmonary toxic responses of nickel oxide nanoparticles in rats","volume":"59","author":"Senoh","year":"2017","journal-title":"J. Occup. Health"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1305","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.accpm.2016.02.007","article-title":"Criteria for choosing an intravenous infusion line intended for multidrug infusion in anaesthesia and intensive care units","volume":"36","author":"Maiguy-Foinard","year":"2017","journal-title":"Anaesthesia Critical Care & Pain Medicine."},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b1310","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1097\/00000539-200211000-00043","article-title":"The delivery rate accuracy of portable infusion pumps used for continuous regional analgesia","volume":"95","author":"Ilfeld","year":"2002","journal-title":"Anesth. Analg."},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1315","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/s10875-010-9373-x","article-title":"Tolerability of a New 10% Liquid Immunoglobulin for Intravenous Use, PrivigenA (R), at Different Infusion Rates","volume":"30","author":"Sleasman","year":"2010","journal-title":"J. Clin. Immunol."},{"issue":"10","key":"10.1016\/j.addr.2023.115044_b1320","first-page":"2531","article-title":"Carmustine infusion reactions are more common with rapid administration","volume":"20","author":"Janson","year":"2012","journal-title":"Support. Care Cancer"},{"issue":"3","key":"10.1016\/j.addr.2023.115044_b1325","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s10875-006-9014-6","article-title":"Safety and tolerability of increased rate of infusion of intravenous immunoglobulin G, 10% in antibody-deficient patients","volume":"26","author":"Gelfand","year":"2006","journal-title":"J. Clin. Immunol."},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b1330","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1158\/1078-0432.CCR-0842-03","article-title":"Comparative pharmacokinetics of weekly and every-three-weeks docetaxel","volume":"10","author":"Baker","year":"2004","journal-title":"Clin. Cancer Res."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b1335","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1080\/10428190600580767","article-title":"A precise pharmacodynamic study showing the advantage of a marked reduction in cardiotoxicity in continuous infusion of doxorubicin","volume":"47","author":"Ishisaka","year":"2006","journal-title":"Leuk. Lymphoma"},{"issue":"5","key":"10.1016\/j.addr.2023.115044_b1340","doi-asserted-by":"crossref","first-page":"427","DOI":"10.5326\/15473317-33-5-427","article-title":"Effect of infusion regime on doxorubicin pharmacokinetics in the cat","volume":"33","author":"Hahn","year":"1997","journal-title":"J. Am. Anim. Hosp. Assoc."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1345","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1023\/A:1025715626164","article-title":"Pharmacokinetic-pharmacodynamic modeling of doxacurium: effect of input rate","volume":"25","author":"Zhu","year":"1997","journal-title":"J. Pharmacokinet. Biopharm."},{"issue":"36","key":"10.1016\/j.addr.2023.115044_b1350","doi-asserted-by":"crossref","first-page":"5719","DOI":"10.1039\/C6PY01113F","article-title":"Poly(D, L-lactic acid)-block-poly(N-(2-hydroxypropyl) methacrylamide) nanoparticles for overcoming accelerated blood clearance and achieving efficient anti-tumor therapy","volume":"7","author":"Du","year":"2016","journal-title":"Polym. Chem."},{"key":"10.1016\/j.addr.2023.115044_b1355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2015.06.023","article-title":"The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes","volume":"213","author":"Kierstead","year":"2015","journal-title":"J. Control. Release"},{"issue":"41","key":"10.1016\/j.addr.2023.115044_b1360","doi-asserted-by":"crossref","first-page":"14473","DOI":"10.1021\/ja054169u","article-title":"Strong Resistance of Phosphorylcholine Self-Assembled Monolayers to Protein Adsorption: Insights into Nonfouling Properties of Zwitterionic Materials","volume":"127","author":"Chen","year":"2005","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1365","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.nantod.2014.02.004","article-title":"Poly(carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production","volume":"9","author":"Yang","year":"2014","journal-title":"Nano Today"},{"issue":"6","key":"10.1016\/j.addr.2023.115044_b1370","doi-asserted-by":"crossref","first-page":"583","DOI":"10.7150\/thno.11234","article-title":"Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon","volume":"5","author":"Li","year":"2015","journal-title":"Theranostics."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1375","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1039\/C7BM00747G","article-title":"Zwitterionic stealth peptide-protected gold nanoparticles enable long circulation without the accelerated blood clearance phenomenon","volume":"6","author":"Zhao","year":"2017","journal-title":"Biomater. Sci."},{"issue":"8","key":"10.1016\/j.addr.2023.115044_b1380","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1021\/ml500112u","article-title":"Factors Influencing in Vivo Disposition of Polymeric Micelles on Multiple Administrations","volume":"5","author":"Hara","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1385","first-page":"44","article-title":"The accelerated blood clearance phenomenon of PEGylated nanoemulsion upon cross administration with nanoemulsions modified with polyglycerin","volume":"13","author":"Su","year":"2018","journal-title":"Asian J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1390","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1084\/jem.20091873","article-title":"Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo","volume":"207","author":"Duong","year":"2010","journal-title":"J. Exp. Med."},{"issue":"9","key":"10.1016\/j.addr.2023.115044_b1395","first-page":"834","volume":"10","author":"Han","year":"2020","journal-title":"Polysialic Acid Modified Liposomes for Improving Pharmacokinetics and Overcoming Accelerated Blood Clearance Phenomenon."},{"key":"10.1016\/j.addr.2023.115044_b1400","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jconrel.2017.01.040","article-title":"Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity","volume":"250","author":"Mima","year":"2017","journal-title":"J. Control. Release"},{"issue":"5473","key":"10.1016\/j.addr.2023.115044_b1405","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1126\/science.288.5473.2051","article-title":"Role of CD47 as a marker of self on red blood cells","volume":"288","author":"Oldenborg","year":"2000","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.addr.2023.115044_b1410","first-page":"25","article-title":"The Interaction Between Signal Regulatory Protein Alpha (SIRP alpha) and CD47: Structure, Function, and Therapeutic Target","volume":"Vol 32","author":"Barclay","year":"2014"},{"issue":"46","key":"10.1016\/j.addr.2023.115044_b1415","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1002\/smll.201502388","article-title":"Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance","volume":"11","author":"Rao","year":"2015","journal-title":"Small"},{"key":"10.1016\/j.addr.2023.115044_b1420","doi-asserted-by":"crossref","DOI":"10.1021\/acsami.2c16457","article-title":"Imaging-Guided Biomimetic M1 Macrophage Membrane-Camouflaged Magnetic Nanorobots for Photothermal Immunotargeting Cancer Therapy","author":"Song","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1425","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-021-00932-2","article-title":"Biomimetic black phosphorus quantum dots-based photothermal therapy combined with anti-PD-L1 treatment inhibits recurrence and metastasis in triple-negative breast cancer","volume":"19","author":"Zhao","year":"2021","journal-title":"J. Nanobiotechnol."},{"issue":"49","key":"10.1016\/j.addr.2023.115044_b1430","article-title":"Strong Penetration-Induced Effective Photothermal Therapy by Exosome-Mediated Black Phosphorus Quantum Dots","volume":"17","author":"Liu","year":"2021","journal-title":"Small"},{"issue":"2","key":"10.1016\/j.addr.2023.115044_b1435","first-page":"247","volume":"14","author":"Ramos","year":"2022","journal-title":"The Hitchhiker\u2019s Guide to Human Therapeutic Nanoparticle Development."},{"issue":"11","key":"10.1016\/j.addr.2023.115044_b1440","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1007\/s13346-022-01149-y","article-title":"Cell-based carrier for targeted hitchhiking delivery","volume":"12","author":"Liu","year":"2022","journal-title":"Drug Deliv. Transl. Res."},{"key":"10.1016\/j.addr.2023.115044_b1445","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jconrel.2014.03.050","article-title":"Cell-mediated delivery of nanoparticles: Taking advantage of circulatory cells to target nanoparticles","volume":"190","author":"Anselmo","year":"2014","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.addr.2023.115044_b1450","first-page":"225","volume":"23","author":"Brenner","year":"2021","journal-title":"Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers."},{"issue":"4","key":"10.1016\/j.addr.2023.115044_b1455","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1016\/j.apsb.2021.09.029","article-title":"The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles","volume":"12","author":"Tang","year":"2022","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.addr.2023.115044_b1460","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111342","article-title":"Advances in the research of nanodrug delivery system for targeted treatment of liver fibrosis","volume":"137","author":"Peng","year":"2021","journal-title":"Biomed. Pharmacother."}],"container-title":["Advanced Drug Delivery Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X23003599?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169409X23003599?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T05:41:34Z","timestamp":1759210894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169409X23003599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":292,"alternative-id":["S0169409X23003599"],"URL":"https:\/\/doi.org\/10.1016\/j.addr.2023.115044","relation":{},"ISSN":["0169-409X"],"issn-type":[{"value":"0169-409X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The interplay between PEGylated nanoparticles and blood immune system","name":"articletitle","label":"Article Title"},{"value":"Advanced Drug Delivery Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.addr.2023.115044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115044"}}