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Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb0345","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1126\/science.284.5414.651","article-title":"Fas-induced caspase denitrosylation","volume":"284","author":"Mannick","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.addr.2025.115718_bb0350","first-page":"1031","article-title":"B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity, blood, the journal of the American society of","volume":"92","author":"Zhao","year":"1998","journal-title":"Hematology"},{"key":"10.1016\/j.addr.2025.115718_bb0355","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ni.2806","article-title":"Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells","volume":"15","author":"Saini","year":"2014","journal-title":"Nat. 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Med."},{"key":"10.1016\/j.addr.2025.115718_bb0370","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1097-4652(199707)172:1<12::AID-JCP2>3.0.CO;2-G","article-title":"Nitric oxide inhibits neutrophil \u03b22 integrin function by inhibiting membrane-associated cyclic GMP synthesis","volume":"172","author":"Banick","year":"1997","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.addr.2025.115718_bb0375","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1096\/fasebj.11.12.9337148","article-title":"Inducible nitric oxide synthase-deficient mice have enhanced leukocyte\u2013endothelium interactions in endotoxemia","volume":"11","author":"Hickey","year":"1997","journal-title":"FASEB J."},{"key":"10.1016\/j.addr.2025.115718_bb0380","doi-asserted-by":"crossref","first-page":"10826","DOI":"10.1074\/jbc.275.15.10826","article-title":"Reactive nitrogen and oxygen species attenuate interleukin-8-induced neutrophil chemotactic activity in vitro","volume":"275","author":"Sato","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.addr.2025.115718_bb0385","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.1158\/0008-5472.CAN-10-2670","article-title":"Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice","volume":"71","author":"Mundy-Bosse","year":"2011","journal-title":"Cancer Res."},{"key":"10.1016\/j.addr.2025.115718_bb0390","doi-asserted-by":"crossref","first-page":"5365","DOI":"10.4049\/jimmunol.1103553","article-title":"Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release","volume":"188","author":"Jayaraman","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb0395","doi-asserted-by":"crossref","first-page":"1908788","DOI":"10.1002\/adfm.201908788","article-title":"Poly (cyclodextrin)-polydrug nanocomplexes as synthetic oncolytic virus for locoregional melanoma chemoimmunotherapy","volume":"30","author":"Kim","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0400","doi-asserted-by":"crossref","first-page":"2946820","DOI":"10.1155\/2020\/2946820","article-title":"Anticancer activity of liquid treated with microwave plasma-generated gas through macrophage activation","volume":"2020","author":"Lee","year":"2020","journal-title":"Oxidative Med. Cell. 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Chem."},{"key":"10.1016\/j.addr.2025.115718_bb0415","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1182\/blood-2005-07-2901","article-title":"Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node\u2013directing chemokine CCL19","volume":"107","author":"Giordano","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.addr.2025.115718_bb0420","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1038\/s41565-019-0570-3","article-title":"Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies","volume":"14","author":"Sung","year":"2019","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.addr.2025.115718_bb0425","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1084\/jem.20121277","article-title":"Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling","volume":"210","author":"Obermajer","year":"2013","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.addr.2025.115718_bb0430","doi-asserted-by":"crossref","first-page":"9220","DOI":"10.1073\/pnas.1100667108","article-title":"Regulation of type 17 helper T-cell function by nitric oxide during inflammation","volume":"108","author":"Niedbala","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb0435","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/nm1609","article-title":"Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer","volume":"13","author":"Nagaraj","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.addr.2025.115718_bb0440","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1002\/eji.201040868","article-title":"Modulation of human T-cell functions by reactive nitrogen species","volume":"41","author":"Kasic","year":"2011","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb0445","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.molimm.2008.10.027","article-title":"Glutathione depletion reveals impairment of antigen processing and inhibition of cathepsin activity by nitric oxide in antigen-presenting cells","volume":"46","author":"Lemaire","year":"2009","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb0450","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1038\/s41467-022-29121-x","article-title":"Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy","volume":"13","author":"Kim","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.addr.2025.115718_bb0455","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.autrev.2013.06.004","article-title":"Innate and adaptive immunity in inflammatory bowel disease","volume":"13","author":"Geremia","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.addr.2025.115718_bb0460","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1021\/ac9801723","article-title":"Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins","volume":"70","author":"Kojima","year":"1998","journal-title":"Anal. Chem."},{"key":"10.1016\/j.addr.2025.115718_bb0465","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1080\/09513590801994063","article-title":"Nitric oxide detection by DAF (diaminofluorescein) fluorescence in human myometrial tissue","volume":"24","author":"Schwendemann","year":"2008","journal-title":"Gynecol. 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Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0510","doi-asserted-by":"crossref","first-page":"3817","DOI":"10.1021\/acs.macromol.5b00996","article-title":"Nitric oxide (NO) cleavable biomimetic thermoresponsive double hydrophilic diblock copolymer with tunable LCST","volume":"48","author":"Hu","year":"2015","journal-title":"Macromolecules"},{"key":"10.1016\/j.addr.2025.115718_bb0515","article-title":"Metal nanozymes modulation of reactive oxygen species as promising strategies for cancer therapy","volume":"124453","author":"Bu","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.addr.2025.115718_bb0520","first-page":"1","article-title":"A review on metal-and metal oxide-based nanozymes: properties, mechanisms, and applications","volume":"13","author":"Liu","year":"2021","journal-title":"Nano Lett."},{"key":"10.1016\/j.addr.2025.115718_bb0525","doi-asserted-by":"crossref","first-page":"12049","DOI":"10.1021\/acsnano.4c02265","article-title":"Transition-metal-based nanozymes: synthesis, mechanisms of therapeutic action, and applications in cancer treatment","volume":"18","author":"Fu","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2025.115718_bb0530","doi-asserted-by":"crossref","first-page":"15783","DOI":"10.1039\/C9NR04771A","article-title":"Metal and metal-oxide nanozymes: bioenzymatic characteristics, catalytic mechanism, and eco-environmental applications","volume":"11","author":"Chen","year":"2019","journal-title":"Nanoscale"},{"key":"10.1016\/j.addr.2025.115718_bb0535","doi-asserted-by":"crossref","first-page":"10324","DOI":"10.1021\/acsnano.0c03807","article-title":"Sustainable nanosheet antioxidants for sepsis therapy via scavenging intracellular reactive oxygen and nitrogen species","volume":"14","author":"Yim","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2025.115718_bb0540","doi-asserted-by":"crossref","first-page":"2402005","DOI":"10.1002\/adhm.202402005","article-title":"Ultrasmall high-entropy-alloy Nanozyme catalyzed in vivo ROS and NO scavenging for anti-inflammatory therapy","volume":"14","author":"Choi","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0545","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.7150\/thno.51912","article-title":"Catalytic patch with redox Cr\/CeO2 nanozyme of noninvasive intervention for brain trauma","volume":"11","author":"Zhang","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.addr.2025.115718_bb0550","article-title":"Atomization-induced high intrinsic activity of a biocompatible MgAl-LDH supported Ru single-atom Nanozyme for efficient radicals scavenging","volume":"62","author":"Wang","year":"2023","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.addr.2025.115718_bb0555","doi-asserted-by":"crossref","first-page":"4896","DOI":"10.1039\/c2cc30485f","article-title":"Cerium oxide nanoparticles scavenge nitric oxide radical ( NO)","volume":"48","author":"Dowding","year":"2012","journal-title":"Chem. Commun."},{"key":"10.1016\/j.addr.2025.115718_bb0560","doi-asserted-by":"crossref","first-page":"8735","DOI":"10.1002\/anie.200801325","article-title":"NO dismutase activity of seven-coordinate manganese (II) Pentaazamacrocyclic complexes","volume":"47","author":"Filipovi\u0107","year":"2008","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.addr.2025.115718_bb0565","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1038\/sj.bjp.0701504","article-title":"Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide-mediated diseases","volume":"122","author":"Fricker","year":"1997","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.addr.2025.115718_bb0570","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2023.158723","article-title":"Cu plasma doping induced cu@ MoS2-PEG nanozymes for highly efficient inhibition of tumor cell multiplication","volume":"643","author":"Liu","year":"2024","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb0575","doi-asserted-by":"crossref","first-page":"1900518","DOI":"10.1002\/adfm.201900518","article-title":"Construction of nanozyme-hydrogel for enhanced capture and elimination of bacteria","volume":"29","author":"Sang","year":"2019","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0580","doi-asserted-by":"crossref","first-page":"59862","DOI":"10.1021\/acsami.4c13220","article-title":"Biomimetic Nanozyme-decorated smart hydrogel for promoting chronic refractory wound healing","volume":"16","author":"Feng","year":"2024","journal-title":"ACS Appl. Mater. 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Lett."},{"key":"10.1016\/j.addr.2025.115718_bb0605","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/s12274-020-3053-9","article-title":"Carbon-based nanozymes for biomedical applications","volume":"14","author":"Ding","year":"2021","journal-title":"Nano Res"},{"key":"10.1016\/j.addr.2025.115718_bb0610","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3390\/molecules30051069","article-title":"Unveiling the role of fractionated graphene oxide in nitric oxide scavenging","volume":"30","author":"Chermashentsev","year":"2025","journal-title":"Molecules"},{"key":"10.1016\/j.addr.2025.115718_bb0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.142338","article-title":"Carbon dots as potential antioxidants for the scavenging of multi-reactive oxygen and nitrogen species","volume":"462","author":"Gao","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.addr.2025.115718_bb0620","doi-asserted-by":"crossref","first-page":"5689","DOI":"10.1021\/acsanm.4c00901","article-title":"Fullerene Nanorings as nitric oxide radical scavengers for ultraviolet-induced cellular injury","volume":"7","author":"Zhang","year":"2024","journal-title":"ACS Applied Nano Materials"},{"key":"10.1016\/j.addr.2025.115718_bb0625","first-page":"eabk1210","article-title":"An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury, science","volume":"7","author":"Mu","year":"2021","journal-title":"Advances"},{"key":"10.1016\/j.addr.2025.115718_bb0630","doi-asserted-by":"crossref","first-page":"4527","DOI":"10.1021\/acs.nanolett.9b01333","article-title":"Carbogenic nanozyme with ultrahigh reactive nitrogen species selectivity for traumatic brain injury","volume":"19","author":"Mu","year":"2019","journal-title":"Nano Lett."},{"key":"10.1016\/j.addr.2025.115718_bb0635","series-title":"Carbon-Based Nanomaterials for Targeted Drug and Gene Delivery Systems","first-page":"455","author":"Makwikwi","year":"2022"},{"key":"10.1016\/j.addr.2025.115718_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.cobme.2021.100262","article-title":"Recent advances in carbon nanomaterials for biomedical applications: a review","volume":"17","author":"Riley","year":"2021","journal-title":"Current Opinion in Biomedical Engineering"},{"key":"10.1016\/j.addr.2025.115718_bb0645","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.carbon.2021.06.002","article-title":"Carbon nanomaterials-based polymer-matrix nanocomposites for antimicrobial applications: a review","volume":"182","author":"Giraud","year":"2021","journal-title":"Carbon"},{"key":"10.1016\/j.addr.2025.115718_bb0650","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1186\/s12951-024-02810-z","article-title":"A carbon dot nanozyme hydrogel enhances pulp regeneration activity by regulating oxidative stress in dental pulpitis","volume":"22","author":"Zhang","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.addr.2025.115718_bb0655","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3390\/antiox13050535","article-title":"Preparation and application of carbon dots nanozymes","volume":"13","author":"Kong","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.addr.2025.115718_bb0660","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.freeradbiomed.2010.03.009","article-title":"Detection of nitric oxide by electron paramagnetic resonance spectroscopy","volume":"49","author":"Hogg","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.addr.2025.115718_bb0665","first-page":"764","article-title":"Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor\/^ NO through a radical reaction","volume":"41","author":"Akaike","year":"1976","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.addr.2025.115718_bb0670","doi-asserted-by":"crossref","first-page":"50949","DOI":"10.1074\/jbc.M308317200","article-title":"Reactions of PTIO and carboxy-PTIO with\u00b7 NO,\u00b7 NO2, and O 2.\u00af","volume":"278","author":"Goldstein","year":"2003","journal-title":"J. Biol. 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Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb0800","first-page":"643","article-title":"Elevated nitric oxide production in rheumatoid arthritis: detection using the fasting urinary nitrate: creatinine ratio, Arthritis & Rheumatism: official journal of the American college of","volume":"39","author":"Grabowski","year":"1996","journal-title":"Rheumatology"},{"key":"10.1016\/j.addr.2025.115718_bb0805","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.3390\/molecules28114414","article-title":"Nitric oxide synthases in rheumatoid arthritis","volume":"28","author":"Huang","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.addr.2025.115718_bb0810","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1136\/ard.51.11.1219","article-title":"Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases","volume":"51","author":"Farrell","year":"1992","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.addr.2025.115718_bb0815","first-page":"165","article-title":"Nitric oxide production in rheumatoid arthritis","volume":"7","author":"Miyasaka","year":"1997","journal-title":"Mod. Rheumatol."},{"key":"10.1016\/j.addr.2025.115718_bb0820","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1093\/rheumatology\/39.9.1004","article-title":"Nitric oxide is a mediator of apoptosis in the rheumatoid joint","volume":"39","author":"Van't Hof","year":"2000","journal-title":"Rheumatology"},{"key":"10.1016\/j.addr.2025.115718_bb0825","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1073\/pnas.91.9.3569","article-title":"Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase","volume":"91","author":"Kasten","year":"1994","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb0830","doi-asserted-by":"crossref","first-page":"21864","DOI":"10.1002\/anie.202010009","article-title":"Breathing micelles for combinatorial treatment of rheumatoid arthritis","volume":"59","author":"Tao","year":"2020","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.addr.2025.115718_bb0835","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.bioactmat.2024.03.002","article-title":"Regulation of rheumatoid arthritis microenvironment via a self-healing injectable hydrogel for improved inflammation elimination and bone repair","volume":"36","author":"Geng","year":"2024","journal-title":"Bioactive Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0840","doi-asserted-by":"crossref","first-page":"5016","DOI":"10.1016\/j.apsb.2023.07.021","article-title":"Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils","volume":"13","author":"Hua","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.addr.2025.115718_bb0845","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110452","article-title":"Oxidative stress and inflammation in osteoarthritis pathogenesis: role of polyphenols","volume":"129","author":"Ansari","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.addr.2025.115718_bb0850","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1002\/art.34453","article-title":"Osteoarthritis: a disease of the joint as an organ","volume":"64","author":"Loeser","year":"2012","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.addr.2025.115718_bb0855","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-025-00594-6","article-title":"Osteoarthritis","volume":"11","author":"Tang","year":"2025","journal-title":"Nat. Rev. Dis. 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Ther."},{"key":"10.1016\/j.addr.2025.115718_bb0890","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1053\/joca.1998.0216","article-title":"Nitric oxide in osteoarthritis","volume":"7","author":"Studer","year":"1999","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.addr.2025.115718_bb0895","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3390\/cells8070734","article-title":"NF-\u03baB signaling pathways in osteoarthritic cartilage destruction","volume":"8","author":"Choi","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.addr.2025.115718_bb0900","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.bioactmat.2024.09.037","article-title":"A natural polyphenolic nanoparticle--knotted hydrogel scavenger for osteoarthritis therapy","volume":"43","author":"Ding","year":"2025","journal-title":"Bioactive Mater."},{"key":"10.1016\/j.addr.2025.115718_bb0905","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0016-5085(98)70646-8","article-title":"The pathobiology of peritonitis","volume":"114","author":"Hall","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.addr.2025.115718_bb0910","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1086\/513658","article-title":"Peritonitis: update on pathophysiology, clinical manifestations, and management","author":"Johnson","year":"1997","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.addr.2025.115718_bb0915","article-title":"Secondary peritonitis: principles of diagnosis and intervention","volume":"361","author":"Ross","year":"2018","journal-title":"Bmj"},{"key":"10.1016\/j.addr.2025.115718_bb0920","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/00005792-198711000-00003","article-title":"Spontaneous bacterial peritonitis: a review of pathogenesis, diagnosis, and treatment","volume":"66","author":"Wilcox","year":"1987","journal-title":"Medicine"},{"key":"10.1016\/j.addr.2025.115718_bb0925","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/bs.ircmb.2022.04.014","article-title":"Innate immune response to peritoneal bacterial infection","volume":"371","author":"Catal\u00e0","year":"2022","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"10.1016\/j.addr.2025.115718_bb0930","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/cc12895","article-title":"Local and systemic innate immune response to secondary human peritonitis","volume":"17","author":"Rich\u00e9","year":"2013","journal-title":"Crit. Care"},{"key":"10.1016\/j.addr.2025.115718_bb0935","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1093\/ndt\/11.12.2466","article-title":"Peritoneal nitric oxide is a marker of peritonitis in patients on continuous ambulatory peritoneal dialysis","volume":"11","author":"Yang","year":"1996","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.addr.2025.115718_bb0940","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/eurheartj\/ehr304","article-title":"Nitric oxide synthases: regulation and function","volume":"33","author":"F\u00f6rstermann","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.addr.2025.115718_bb0945","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1034\/j.1600-065X.2000.917307.x","article-title":"The role of nitric oxide in innate immunity","volume":"173","author":"Bogdan","year":"2000","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.addr.2025.115718_bb0950","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.freeradbiomed.2006.05.011","article-title":"Nitric oxide and reactive nitrogen species in airway epithelial signaling and inflammation","volume":"41","author":"Bove","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.addr.2025.115718_bb0955","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.abb.2003.12.017","article-title":"Reactive nitrogen species in the chemical biology of inflammation","volume":"423","author":"Dedon","year":"2004","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.addr.2025.115718_bb0960","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jconrel.2024.08.026","article-title":"Tailored small molecule for inflammation treatment: dual scavenger targeting nitric oxide and reactive oxygen species","volume":"374","author":"Nah","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.addr.2025.115718_bb0965","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neures.2013.10.004","article-title":"Neuroinflammation: the role and consequences","volume":"79","author":"Lyman","year":"2014","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.addr.2025.115718_bb0970","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1080\/00207454.2016.1212854","article-title":"Neuroinflammation pathways: a general review","volume":"127","author":"Shabab","year":"2017","journal-title":"Int. J. 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Med."},{"key":"10.1016\/j.addr.2025.115718_bb1025","doi-asserted-by":"crossref","first-page":"4771","DOI":"10.3390\/ijms22094771","article-title":"Nitric oxide as a target for phytochemicals in anti-neuroinflammatory prevention therapy","volume":"22","author":"Subedi","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb1030","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.niox.2010.06.001","article-title":"Nitric oxide and neuronal death","volume":"23","author":"Brown","year":"2010","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.addr.2025.115718_bb1035","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.brainresrev.2007.02.001","article-title":"Apoptotic neuronal death in Parkinson's disease: involvement of nitric oxide","volume":"54","author":"Singh","year":"2007","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.addr.2025.115718_bb1040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3181\/00379727-211-43950E","article-title":"Nitric oxide in neuronal degeneration","volume":"211","author":"Dawson","year":"1996","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.addr.2025.115718_bb1045","doi-asserted-by":"crossref","first-page":"5938","DOI":"10.3390\/ijms23115938","article-title":"An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases","volume":"23","author":"Teleanu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb1050","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0165-0173(99)00014-4","article-title":"Neurodegenerative disorders: the role of peroxynitrite","volume":"30","author":"Torreilles","year":"1999","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.addr.2025.115718_bb1055","doi-asserted-by":"crossref","first-page":"46213","DOI":"10.1021\/acsami.1c06449","article-title":"A co-doped Fe3O4 nanozyme shows enhanced reactive oxygen and nitrogen species scavenging activity and ameliorates the deleterious effects of ischemic stroke","volume":"13","author":"Liu","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.addr.2025.115718_bb1060","doi-asserted-by":"crossref","first-page":"F1","DOI":"10.1152\/ajprenal.00424.2007","article-title":"Nitric oxide deficiency in chronic kidney disease","volume":"294","author":"Baylis","year":"2008","journal-title":"American journal of physiology-renal, Physiology"},{"key":"10.1016\/j.addr.2025.115718_bb1065","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115325","article-title":"Nitric oxide deficiency is a primary driver of hypertension","volume":"206","author":"Bryan","year":"2022","journal-title":"Biochem. 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Lett."},{"key":"10.1016\/j.addr.2025.115718_bb1160","doi-asserted-by":"crossref","first-page":"625","DOI":"10.2174\/1568026054679380","article-title":"Nitric oxide (NO)-and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities","volume":"5","author":"Keefer","year":"2005","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.addr.2025.115718_bb1165","doi-asserted-by":"crossref","first-page":"5473","DOI":"10.1021\/ja002899q","article-title":"Chemistry of the diazeniumdiolates. 2. Kinetics and mechanism of dissociation to nitric oxide in aqueous solution","volume":"123","author":"Davies","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.addr.2025.115718_bb1170","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1021\/tx960183w","article-title":"Measurement and modeling of nitric oxide release rates for nitric oxide donors","volume":"10","author":"Ramamurthi","year":"1997","journal-title":"Chem. Res. 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B: Biointerfaces"},{"key":"10.1016\/j.addr.2025.115718_bb1360","doi-asserted-by":"crossref","first-page":"1704490","DOI":"10.1002\/adma.201704490","article-title":"Dual intratumoral redox\/enzyme-responsive NO-releasing nanomedicine for the specific, high-efficacy, and low-toxic cancer therapy","volume":"30","author":"Jia","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.addr.2025.115718_bb1365","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1039\/C7NR00231A","article-title":"MRI-guided and ultrasound-triggered release of NO by advanced nanomedicine","volume":"9","author":"Jin","year":"2017","journal-title":"Nanoscale"},{"key":"10.1016\/j.addr.2025.115718_bb1370","doi-asserted-by":"crossref","first-page":"13266","DOI":"10.1021\/ja300771w","article-title":"Quantum dot photoluminescence quenching by Cr (III) complexes. Photosensitized reactions and evidence for a FRET mechanism","volume":"134","author":"Burks","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.addr.2025.115718_bb1375","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1039\/C6SC02774A","article-title":"Controllable NO release from cu(1.6)S nanoparticle decomposition of S-nitrosoglutathiones following photothermal disintegration of polymersomes to elicit cerebral vasodilatory activity","volume":"8","author":"Kao","year":"2017","journal-title":"Chem. Sci."},{"key":"10.1016\/j.addr.2025.115718_bb1380","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1039\/D0NR07484E","article-title":"Advanced nitric oxide donors: chemical structure of NO drugs, NO nanomedicines and biomedical applications","volume":"13","author":"Yang","year":"2021","journal-title":"Nanoscale"},{"key":"10.1016\/j.addr.2025.115718_bb1385","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nrc.2016.108","article-title":"Cancer nanomedicine: progress, challenges and opportunities","volume":"17","author":"Shi","year":"2017","journal-title":"Nat. Rev. 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Release"},{"key":"10.1016\/j.addr.2025.115718_bb1540","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.imlet.2004.03.002","article-title":"Effect of nitric oxide in the differentiation of human monocytes to dendritic cells","volume":"93","author":"Fern\u00e1ndez-Ruiz","year":"2004","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.addr.2025.115718_bb1545","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1016\/j.bbagen.2012.10.019","article-title":"Nitric oxide depletion alters hematopoietic stem cell commitment toward immunogenic dendritic cells","volume":"1830","author":"Tiribuzi","year":"2013","journal-title":"Biochimica et Biophysica Acta (BBA)-General Subjects"},{"key":"10.1016\/j.addr.2025.115718_bb1550","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1189\/jlb.0902447","article-title":"Synergism of nitric oxide and maturation signals on human dendritic cells occurs through a cyclic GMP-dependent pathway","volume":"73","author":"Paolucci","year":"2003","journal-title":"Journal of Leucocyte Biology"},{"key":"10.1016\/j.addr.2025.115718_bb1555","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.3390\/cells10102655","article-title":"Regulation of T cells in cancer by nitric oxide","volume":"10","author":"Navasardyan","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.addr.2025.115718_bb1560","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002325","article-title":"TNF-\u03b1 and CD8+ T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis","volume":"7","author":"Bernardino","year":"2013","journal-title":"PLoS Negl. 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Dis."},{"key":"10.1016\/j.addr.2025.115718_bb1585","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1002\/(SICI)1521-4141(199808)28:08<2276::AID-IMMU2276>3.0.CO;2-H","article-title":"Co-stimulatory effect of nitric oxide on endothelial NF-\u03baB implies a physiological self-amplifying mechanism","volume":"28","author":"Umansky","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.addr.2025.115718_bb1590","doi-asserted-by":"crossref","first-page":"3873","DOI":"10.4049\/jimmunol.166.6.3873","article-title":"Biphasic regulation of NF-\u03baB activity underlies the pro-and anti-inflammatory actions of nitric oxide","volume":"166","author":"Connelly","year":"2001","journal-title":"J. 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