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Res."},{"key":"10.1016\/j.addr.2026.115977_bb0945","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1557\/mrs.2020.301","article-title":"Liquid\u2013liquid phase separation of proteins and peptides derived from biological materials: discovery, protein engineering, and emerging applications","volume":"45","author":"Sun","year":"2020","journal-title":"MRS Bull."},{"issue":"2008","key":"10.1016\/j.addr.2026.115977_bb0950","first-page":"1816","article-title":"The transition from stiff to compliant materials in squid beaks","volume":"319","author":"Miserez","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.addr.2026.115977_bb0955","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/nchembio.1833","article-title":"Infiltration of chitin by protein coacervates defines the squid beak mechanical gradient","volume":"11","author":"Tan","year":"2015","journal-title":"Nat. Chem. 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Res."},{"key":"10.1016\/j.addr.2026.115977_bb1110","first-page":"1309","article-title":"Physiological barriers to nucleic acid therapeutics and engineering strategies for lipid nanoparticle design","volume":"17","author":"Kim","year":"2025","journal-title":"Optimization, and Clinical Translation, Pharmaceutics"},{"key":"10.1016\/j.addr.2026.115977_bb1115","doi-asserted-by":"crossref","first-page":"10025","DOI":"10.1021\/acs.nanolett.2c03741","article-title":"The extent to which lipid nanoparticles require apolipoprotein E and low-density lipoprotein receptor for delivery changes with ionizable lipid structure","volume":"22","author":"Paunovska","year":"2022","journal-title":"Nano Lett."},{"key":"10.1016\/j.addr.2026.115977_bb1120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/nrd1632","article-title":"Recent advances with liposomes as pharmaceutical carriers","volume":"4","author":"Torchilin","year":"2005","journal-title":"Nat. Rev. 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Res."},{"key":"10.1016\/j.addr.2026.115977_bb1155","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/s41557-021-00854-4","article-title":"Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics","volume":"14","author":"Sun","year":"2022","journal-title":"Nat. Chem."},{"key":"10.1016\/j.addr.2026.115977_bb1160","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1021\/acsnano.5c13501","article-title":"Redox-responsive peptide coacervates for enhanced mRNA delivery and intracellular release","volume":"20","author":"Ren","year":"2026","journal-title":"ACS Nano"},{"key":"10.1016\/j.addr.2026.115977_bb1165","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/s41392-021-00572-w","article-title":"Small molecules in targeted cancer therapy: advances, challenges, and future perspectives","volume":"6","author":"Zhong","year":"2021","journal-title":"Signal Transduct. Target. 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Oncol."},{"key":"10.1016\/j.addr.2026.115977_bb1210","article-title":"Inhibition of Cancer causing genes through the delivery of OmoMyc in anti-Myc therapy","author":"McGraw","year":"2020","journal-title":"a Systematic Review"},{"key":"10.1016\/j.addr.2026.115977_bb1215","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1021\/acs.molpharmaceut.5c00468","article-title":"Engineered peptide Coacervates enable efficient intracellular delivery of the MYC inhibitor omoMYC","volume":"22","author":"Cerrato","year":"2025","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.addr.2026.115977_bb1220","doi-asserted-by":"crossref","first-page":"2411967","DOI":"10.1002\/adma.202411967","article-title":"Catalytic biomaterials-activated in situ chemical reactions: strategic modulation and enhanced disease treatment","volume":"37","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.addr.2026.115977_bb1225","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.bios.2016.07.039","article-title":"Reversibly monitoring oxidation and reduction events in living biological systems: recent development of redox-responsive reversible NIR biosensors and their applications in in vitro\/in vivo fluorescence imaging","volume":"86","author":"Chu","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.addr.2026.115977_bb1230","first-page":"307","article-title":"Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels","volume":"62","author":"Kuppusamy","year":"2002","journal-title":"Cancer Res."},{"key":"10.1016\/j.addr.2026.115977_bb1235","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.3390\/cells14151207","article-title":"Reactive oxygen species: a double-edged sword in the modulation of cancer signaling pathway dynamics","volume":"14","author":"Nigam","year":"2025","journal-title":"Cells"},{"key":"10.1016\/j.addr.2026.115977_bb1240","article-title":"Retinal gene therapies for inherited ocular diseases: translational delivery strategies from bench to bedside","volume":"114841","author":"Haddadzadegan","year":"2026","journal-title":"J. Control. 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Eng."},{"key":"10.1016\/j.addr.2026.115977_bb1335","article-title":"Peptide synthesis: a review of classical and emerging methods","volume":"18","author":"Cai","year":"2025","journal-title":"Biofabrication"},{"key":"10.1016\/j.addr.2026.115977_bb1340","doi-asserted-by":"crossref","first-page":"4261","DOI":"10.1021\/acs.joc.3c01494","article-title":"Process mass intensity (PMI): a holistic analysis of current peptide manufacturing processes informs sustainability in peptide synthesis","volume":"89","author":"Kekessie","year":"2024","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.addr.2026.115977_bb1345","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1039\/C7OB02759A","article-title":"The renascence of continuous-flow peptide synthesis\u2013an abridged account of solid and solution-based approaches","volume":"16","author":"Gordon","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.addr.2026.115977_bb1350","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.30574\/ijsra.2024.12.1.1108","article-title":"Analytical techniques for peptide-based drug development: characterization, stability, and quality control","volume":"12","author":"Patel","year":"2024","journal-title":"Int. J. Sci. Res. Archive"},{"key":"10.1016\/j.addr.2026.115977_bb1355","doi-asserted-by":"crossref","first-page":"915","DOI":"10.3109\/03639049709148696","article-title":"Analysis of peptides and proteins: evaluation of purity, stability, and structural characterization of insulin","volume":"23","author":"Oliva","year":"1997","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.addr.2026.115977_bb1360","doi-asserted-by":"crossref","first-page":"8730","DOI":"10.1021\/ja211725s","article-title":"A totally synthetic, self-assembling, adjuvant-free MUC1 glycopeptide vaccine for cancer therapy","volume":"134","author":"Huang","year":"2012","journal-title":"J. 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