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Thirty\u2010five adolescents with AS and 35 controls matched on chronological age, school year and gender distribution, completed questionnaires designed to ascertain the quality of their best\u2010friendship, motivation for developing friendships, feelings of loneliness and depressive symptomatology. Relative to the comparison group, the participants with AS reported poorer quality of best\u2010friendship and less motivation to develop friendships. The individuals with AS displayed higher levels of loneliness and depressive symptoms, with loneliness being negatively correlated with the quality of their best\u2010friendship. Increased levels of loneliness in the adolescents with AS was predicted by the extent to which their best\u2010friendships were characterized by high levels of conflict\/betrayal. Increased depressive symptoms in the adolescents with AS were also predicted by this factor. The findings indicate that increased levels of negative affect may be related to the poor quality of social relationships often reported in this population.<\/jats:p>","DOI":"10.1016\/j.adolescence.2008.03.004","type":"journal-article","created":{"date-parts":[[2008,8,13]],"date-time":"2008-08-13T20:45:39Z","timestamp":1218660339000},"page":"309-322","source":"Crossref","is-referenced-by-count":229,"title":["Friendship, loneliness and depression in adolescents with Asperger's Syndrome"],"prefix":"10.1002","volume":"32","author":[{"given":"Andrew J.O.","family":"Whitehouse","sequence":"first","affiliation":[{"name":"Department of Experimental Psychology University of Oxford Oxford UK"},{"name":"School of Psychology University of Western Australia Crawley Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Durkin","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Strathclyde Glasgow 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