{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T07:02:23Z","timestamp":1773644543209,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T00:00:00Z","timestamp":1621468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["advancesradonc.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.adro.2021.100729","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:49:19Z","timestamp":1622162959000},"page":"100729","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effective Pain Control With Very Low Dose Palliative Radiation Therapy for Patients With Multiple Myeloma With Uncomplicated Osseous Lesions"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8012-098X","authenticated-orcid":false,"given":"Jeremy G.","family":"Price","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Niedzwiecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taofik","family":"Oyekunle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat O.","family":"Arcasoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin E.","family":"Champ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris R.","family":"Kelsey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph K.","family":"Salama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Moravan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.adro.2021.100729_bib0001","doi-asserted-by":"crossref","first-page":"e538","DOI":"10.1016\/S1470-2045(14)70442-5","article-title":"International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma","volume":"15","author":"Rajkumar","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0002","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.ijrobp.2018.05.009","article-title":"Radiation therapy for solitary plasmacytoma and multiple myeloma: Guidelines from the International Lymphoma Radiation Oncology Group","volume":"101","author":"Tsang","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2021.100729_bib0003","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/s00066-017-1154-5","article-title":"Single vs. multiple fraction regimens for palliative radiotherapy treatment of multiple myeloma: A prospective randomised study","volume":"193","author":"Rudzianskiene","year":"2017","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.adro.2021.100729_bib0004","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1038\/leu.2013.313","article-title":"Continued improvement in survival in multiple myeloma: Changes in early mortality and outcomes in older patients","volume":"28","author":"Kumar","year":"2014","journal-title":"Leukemia"},{"key":"10.1016\/j.adro.2021.100729_bib0005","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0360-3016(93)90308-I","article-title":"Radiation therapy for the palliation of multiple myeloma","volume":"25","author":"Leigh","year":"1993","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2021.100729_bib0006","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3857\/roj.2016.34.1.59","article-title":"Local radiotherapy for palliation in multiple myeloma patients with symptomatic bone lesions","volume":"34","author":"Lee","year":"2016","journal-title":"Radiat Oncol J"},{"key":"10.1016\/j.adro.2021.100729_bib0007","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.ijrobp.2005.10.018","article-title":"Short-course radiotherapy is not optimal for spinal cord compression due to myeloma","volume":"64","author":"Rades","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2021.100729_bib0008","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s13014-015-0374-z","article-title":"Effects of radiotherapy in the treatment of multiple myeloma: A retrospective analysis of a single institution","volume":"10","author":"Matuschek","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0009","doi-asserted-by":"crossref","first-page":"e400","DOI":"10.1016\/j.prro.2019.02.009","article-title":"Dose selection for multiple myeloma in modern era","volume":"9","author":"Wang","year":"2019","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0010","doi-asserted-by":"crossref","first-page":"e355","DOI":"10.3324\/haematol.2019.235804","article-title":"New paradigm for radiation in multiple myeloma: Lower yet effective dose to avoid radiation toxicity","volume":"105","author":"Elhammali","year":"2020","journal-title":"Haematologica"},{"key":"10.1016\/j.adro.2021.100729_bib0011","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1200\/JCO.2014.55.1143","article-title":"Role of radiation therapy in palliative care of the patient with cancer","volume":"32","author":"Lutz","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0012","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S1470-2045(13)70556-4","article-title":"Single versus multiple fractions of repeat radiation for painful bone metastases: A randomised, controlled, non-inferiority trial","volume":"15","author":"Chow","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0013","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1182\/blood.V73.6.1677.1677","article-title":"Hematopoietic bone marrow recovery after radiation therapy: MRI evaluation","volume":"73","author":"Casamassima","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.adro.2021.100729_bib0014","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.adro.2018.09.009","article-title":"The safety profile of concurrent therapy for multiple myeloma in the modern era","volume":"4","author":"Resende Salgado","year":"2019","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.adro.2021.100729_bib0015","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.clml.2014.07.010","article-title":"Feasibility and efficacy of local radiotherapy with concurrent novel agents in patients with multiple myeloma","volume":"14","author":"Shin","year":"2014","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"10.1016\/j.adro.2021.100729_bib0016","doi-asserted-by":"crossref","first-page":"3252","DOI":"10.1001\/archinte.160.21.3252","article-title":"Are patients at Veterans Affairs medical centers sicker? A comparative analysis of health status and medical resource use","volume":"160","author":"Agha","year":"2000","journal-title":"Arch Intern Med"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109421000877?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109421000877?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:39:05Z","timestamp":1762529945000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452109421000877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S2452109421000877"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2021.100729","relation":{},"ISSN":["2452-1094"],"issn-type":[{"value":"2452-1094","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effective Pain Control With Very Low Dose Palliative Radiation Therapy for Patients With Multiple Myeloma With Uncomplicated Osseous Lesions","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2021.100729","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"100729"}}