{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:50:45Z","timestamp":1762530645990,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["advancesradonc.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.adro.2023.101393","type":"journal-article","created":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T02:44:50Z","timestamp":1697856290000},"page":"101393","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["NTCP Modeling and Dose-Volume Correlations of Significant Hematocrit Drop 3 Months After Prostate Radiation Therapy"],"prefix":"10.1016","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-5420","authenticated-orcid":false,"given":"Panos","family":"Papanikolaou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Swanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotirios","family":"Stathakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panayiotis","family":"Mavroidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.adro.2023.101393_bib0001","doi-asserted-by":"crossref","first-page":"628","DOI":"10.6004\/jnccn.2012.0064","article-title":"Cancer- and chemotherapy-induced anemia","volume":"10","author":"Rodgers","year":"2012","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.adro.2023.101393_bib0002","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2147\/CLEP.S89480","article-title":"Incidence of anemia in patients diagnosed with solid tumors receiving chemotherapy, 2010-2013","volume":"8","author":"Xu","year":"2016","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.adro.2023.101393_bib0003","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/0360-3016(94)00430-S","article-title":"Hematopoietic stem cell compartment: Acute and late effects of radiation therapy and chemotherapy","volume":"31","author":"Mauch","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2023.101393_bib0004","series-title":"Metastasis","first-page":"109","article-title":"Hematological toxicity induced by bone metastasis radiation therapy","author":"Vazquez","year":"2022"},{"key":"10.1016\/j.adro.2023.101393_bib0005","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/ijgc-00009577-200209000-00009","article-title":"Concomitant cisplatin and extended field radiation therapy in patients with cervical and endometrial cancer","volume":"12","author":"Sood","year":"2002","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.adro.2023.101393_bib0006","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.ijrobp.2009.12.025","article-title":"Radiation-related predictors of hematologic toxicity after concurrent chemoradiation for cervical cancer and implications for bone marrow-sparing pelvic IMRT","volume":"79","author":"Albuquerque","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2023.101393_bib0007","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1088\/0031-9155\/5\/3\/302","article-title":"The distribution of active bone marrow in the adult","volume":"5","author":"Elllis","year":"1961","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.adro.2023.101393_bib0008","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1080\/028418699432950","article-title":"Optimization of the dose level for a given for a given treatment plan to maximize the complication-free tumor cure","volume":"38","author":"Lind","year":"1999","journal-title":"Acta Oncol"},{"key":"10.1016\/j.adro.2023.101393_bib0009","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.meddos.2014.06.001","article-title":"Radiobiological comparison of helical tomotherapy, intensity modulated radiotherapy, and conformal radiotherapy accounting for secondary malignancy risks","volume":"39","author":"Komisopoulos","year":"2014","journal-title":"Med Dosim"},{"key":"10.1016\/j.adro.2023.101393_bib0010","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1088\/0031-9155\/37\/4\/004","article-title":"An algorithm for maximizing the probability of complication free tumor control in radiation therapy","volume":"37","author":"K\u00e4llman","year":"1992","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.adro.2023.101393_bib0011","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1088\/0031-9155\/46\/10\/307","article-title":"Biologically effective uniform dose for specification, report and comparison of dose response relations and treatment plans","volume":"46","author":"Mavroidis","year":"2001","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.adro.2023.101393_bib0012","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/0360-3016(90)90037-K","article-title":"Optimization of uncomplicated control for head and neck tumors","volume":"19","author":"\u00c5gren-Cronqvist","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2023.101393_bib0013","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/09553009214552071","article-title":"Tumor and normal tissue responses to fractionated non uniform dose delivery","volume":"62","author":"K\u00e4llman","year":"1992","journal-title":"Int J Radiat Biol"},{"key":"10.1016\/j.adro.2023.101393_bib0014","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0360-3016(80)90042-5","article-title":"Methods for extracting dose-response curves from radiation therapy data, I: A unified approach","volume":"6","author":"Herring","year":"1980","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2023.101393_bib0015","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1080\/02841860310012833","article-title":"Determination and clinical verification of dose-response parameters for esophageal stricture from head and neck radiotherapy","volume":"42","author":"Mavroidis","year":"2003","journal-title":"Acta Oncol"},{"key":"10.1016\/j.adro.2023.101393_bib0016","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s13014-021-01786-6","article-title":"NTCP modeling and dose-volume correlations for acute xerostomia and dry eye after whole brain radiation","volume":"16","author":"Mavroidis","year":"2021","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.adro.2023.101393_bib0017","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.143.1.7063747","article-title":"The meaning and use of the area under a receiver operating characteristic (ROC) curve","volume":"143","author":"Hanley","year":"1982","journal-title":"Radiology"},{"key":"10.1016\/j.adro.2023.101393_bib0018","unstructured":"Hematocrit. MedlinePlus. National Library of Medicine. Accessed May 6, 2019.https:\/\/medlineplus.gov\/ency\/article\/003646.htm#: \u223c:text=Hematocrit%20is%20a%20blood%20test,of%20the%20 red%20blood%20cells."},{"key":"10.1016\/j.adro.2023.101393_bib0019","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1046\/j.1537-2995.1981.21481275998.x","article-title":"The effects of irradiation on blood components","volume":"21","author":"Button","year":"1981","journal-title":"Transfusion"},{"key":"10.1016\/j.adro.2023.101393_bib0020","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/00004032-200305000-00001","article-title":"Dose response relationships for acute ionizing-radiation lethality","volume":"84","author":"Anno","year":"2003","journal-title":"Health Phys"},{"key":"10.1016\/j.adro.2023.101393_bib0021","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1038\/s41409-020-0799-3","article-title":"Total body irradiation (18\u2009Gy) without chemotherapy as conditioning for allogeneic hematopoietic cell transplantation in refractory acute myeloid leukemia","volume":"55","author":"Altouri","year":"2020","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.adro.2023.101393_bib0022","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/S0360-3016(02)03801-4","article-title":"Impact of intensity-modulated radiotherapy on acute hematologic toxicity in women with gynecologic malignancies","volume":"54","author":"Brixey","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl 2","key":"10.1016\/j.adro.2023.101393_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1634\/theoncologist.5-suppl_2-1","article-title":"Radiotherapy-associated anemia: The scope of the problem","volume":"5","author":"Harrison","year":"2000","journal-title":"Oncologist"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245210942300221X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245210942300221X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:43:50Z","timestamp":1762530230000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S245210942300221X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S245210942300221X"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2023.101393","relation":{},"ISSN":["2452-1094"],"issn-type":[{"type":"print","value":"2452-1094"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NTCP Modeling and Dose-Volume Correlations of Significant Hematocrit Drop 3 Months After Prostate Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2023.101393","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"101393"}}