{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T05:26:06Z","timestamp":1791437166946,"version":"4.3.3"},"reference-count":43,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005043","name":"Fonds Joseph Maisin","doi-asserted-by":"publisher","award":["_ 282-770\\u20191872"],"award-info":[{"award-number":["_ 282-770\\u20191872"]}],"id":[{"id":"10.13039\/501100005043","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001866","name":"Fonds National de la Recherche Luxembourg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001866","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002661","name":"Fonds de la Recherche Scientific","doi-asserted-by":"publisher","award":["33411"],"award-info":[{"award-number":["33411"]}],"id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","advancesradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.adro.2024.101563","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T07:03:38Z","timestamp":1719990218000},"page":"101563","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Lung and Liver Stereotactic Body Radiation Therapy During Mechanically Assisted Deep Inspiration Breath-Holds: A Prospective Feasibility Trial"],"prefix":"10.1016","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6596-2433","authenticated-orcid":false,"given":"Lo\u00efc","family":"Vander Veken","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Van Ooteghem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Ghaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane","family":"Razavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Dechambre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Geets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.adro.2024.101563_bib0001","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1002\/mp.12227","article-title":"Motion management strategies and technical issues associated with stereotactic body radiotherapy of thoracic and upper abdominal tumors: A review from NRG oncology","volume":"44","author":"Brandner","year":"2017","journal-title":"Med Phys"},{"issue":"4","key":"10.1016\/j.adro.2024.101563_bib0002","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.ijrobp.2007.11.042","article-title":"Comparison of different strategies to use four-dimensional computed tomography in treatment planning for lung cancer patients","volume":"70","author":"Wolthaus","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"11","key":"10.1016\/j.adro.2024.101563_bib0003","doi-asserted-by":"crossref","first-page":"e13810","DOI":"10.1002\/acm2.13810","article-title":"Results from the AAPM Task Group 324 respiratory motion management in radiation oncology survey","volume":"23","author":"Ball","year":"2022","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.adro.2024.101563_bib0004","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.radonc.2020.06.018","article-title":"Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management","volume":"153","author":"Anastasi","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.adro.2024.101563_bib0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ejmp.2021.10.010","article-title":"Incorporation of tumor motion directionality in margin recipe: The directional MidP strategy","volume":"91","author":"Vander Veken","year":"2021","journal-title":"Phys Med"},{"issue":"3","key":"10.1016\/j.adro.2024.101563_bib0006","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.radonc.2013.10.025","article-title":"Validation of the mid-position strategy for lung tumors in helical TomoTherapy","volume":"110","author":"Wanet","year":"2014","journal-title":"Radiother Oncol"},{"issue":"3","key":"10.1016\/j.adro.2024.101563_bib0007","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.ijrobp.2015.02.015","article-title":"Dosimetric advantages of midventilation compared with internal target volume for radiation therapy of pancreatic cancer","volume":"92","author":"Lens","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0008","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ijrobp.2018.09.024","article-title":"Dosimetric benefits of midposition compared with internal target volume strategy for esophageal cancer radiation therapy","volume":"103","author":"Jin","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10.1016\/j.adro.2024.101563_bib0009","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.meddos.2021.02.002","article-title":"Feasibility of a TPS-integrated method to incorporate tumor motion in the margin recipe","volume":"46","author":"Dechambre","year":"2021","journal-title":"Med Dosim"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0010","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.radonc.2017.09.001","article-title":"The long- and short-term variability of breathing induced tumor motion in lung and liver over the course of a radiotherapy treatment","volume":"126","author":"Dhont","year":"2018","journal-title":"Radiother Oncol"},{"issue":"15","key":"10.1016\/j.adro.2024.101563_bib0011","doi-asserted-by":"crossref","first-page":"15TR01","DOI":"10.1088\/1361-6560\/ab2ba8","article-title":"Real-time intrafraction motion monitoring in external beam radiotherapy","volume":"64","author":"Bertholet","year":"2019","journal-title":"Phys Med Biol"},{"issue":"1","key":"10.1016\/j.adro.2024.101563_bib0012","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.radonc.2017.02.003","article-title":"Target position uncertainty during visually guided deep-inspiration breath-hold radiotherapy in locally advanced lung cancer","volume":"123","author":"Scherman Rydh\u00f6g","year":"2017","journal-title":"Radiother Oncol"},{"issue":"11","key":"10.1016\/j.adro.2024.101563_bib0013","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1080\/0284186X.2016.1221532","article-title":"Considerable pancreatic tumor motion during breath-holding","volume":"55","author":"Lens","year":"2016","journal-title":"Acta Oncol"},{"issue":"1116","key":"10.1016\/j.adro.2024.101563_bib0014","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20200859","article-title":"Intrafractional fiducial marker position variations in stereotactic liver radiotherapy during voluntary deep inspiration breath-hold","volume":"93","author":"Stick","year":"2020","journal-title":"Br J Radiol"},{"key":"10.1016\/j.adro.2024.101563_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2023.109573","article-title":"Evaluation of the four-dimensional motion of lung tumors during end-exhalation breath-hold conditions using volumetric cine computed tomography images","volume":"182","author":"Kamima","year":"2023","journal-title":"Radiother Oncol"},{"issue":"1104","key":"10.1016\/j.adro.2024.101563_bib0016","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20190569","article-title":"Deep inspiration breath hold in locally advanced lung cancer radiotherapy: validation of intrafractional geometric uncertainties in the INHALE trial","volume":"92","author":"Josipovic","year":"2019","journal-title":"Br J Radiol"},{"issue":"1062","key":"10.1016\/j.adro.2024.101563_bib0017","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20150741","article-title":"Reducing the within-patient variability of breathing for radiotherapy delivery in conscious, unsedated cancer patients using a mechanical ventilator","volume":"89","author":"Parkes","year":"2016","journal-title":"Br J Radiol"},{"key":"10.1016\/j.adro.2024.101563_bib0018","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.radonc.2019.09.021","article-title":"Mechanically-assisted and non-invasive ventilation for radiation therapy: A safe technique to regularize and modulate internal tumour motion","volume":"141","author":"Van Ooteghem","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.adro.2024.101563_bib0019","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.radonc.2018.12.026","article-title":"Mechanically-assisted non-invasive ventilation: A step forward to modulate and to improve the reproducibility of breathing-related motion in radiation therapy","volume":"133","author":"Van Ooteghem","year":"2019","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.adro.2024.101563_bib0020","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.ijrobp.2018.11.040","article-title":"Mitigating respiratory motion in radiation therapy: rapid, shallow, non-invasive mechanical ventilation for internal thoracic targets","volume":"103","author":"West","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2024.101563_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2023.109598","article-title":"Voluntary versus mechanically-induced deep inspiration breath-hold for left breast cancer: a randomized controlled trial","volume":"183","author":"Vander Veken","year":"2023","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.adro.2024.101563_bib0022","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/S0360-3016(00)00518-6","article-title":"The probability of correct target dosage: dose-population histograms for deriving treatment margins in radiotherapy","volume":"47","author":"van Herk","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0023","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.ijrobp.2008.08.004","article-title":"Frameless stereotactic body radiotherapy for lung cancer using four-dimensional cone beam CT guidance","volume":"74","author":"Sonke","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.adro.2024.101563_bib0024","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.ijrobp.2009.03.058","article-title":"Inter- and intrafraction variability in liver position in non\u2013breath-hold stereotactic body radiotherapy","volume":"75","author":"Case","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"10.1016\/j.adro.2024.101563_bib0025","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.clon.2022.02.010","article-title":"UK 2022 consensus on normal tissue dose-volume constraints for oligometastatic, primary lung and hepatocellular carcinoma stereotactic ablative radiotherapy","volume":"34","author":"Diez","year":"2022","journal-title":"Clin Oncol"},{"issue":"5","key":"10.1016\/j.adro.2024.101563_bib0026","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.ijrobp.2008.07.037","article-title":"A method to estimate mean position, motion magnitude, motion correlation, and trajectory of a tumor from cone-beam CT projections for image-guided radiotherapy","volume":"72","author":"Poulsen","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"10.1016\/j.adro.2024.101563_bib0027","doi-asserted-by":"crossref","DOI":"10.1088\/2057-1976\/abb18e","article-title":"Improvement of kilovoltage intrafraction monitoring accuracy through gantry angles selection","volume":"6","author":"Vander Veken","year":"2020","journal-title":"Biomed Phys Eng Express"},{"issue":"6","key":"10.1016\/j.adro.2024.101563_bib0028","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/sim.721","article-title":"Sample size tables for exact single-stage phase II designs","volume":"20","author":"A'Hern","year":"2001","journal-title":"Stat Med"},{"issue":"1","key":"10.1016\/j.adro.2024.101563_bib0029","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Ser B Methodol"},{"issue":"6","key":"10.1016\/j.adro.2024.101563_bib0030","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/bja\/aet070","article-title":"Complications of non-invasive ventilation techniques: a comprehensive qualitative review of randomized trials","volume":"110","author":"Carron","year":"2013","journal-title":"Br J Anaesth"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0031","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.radonc.2016.09.012","article-title":"Abdominal organ motion during inhalation and exhalation breath-holds: pancreatic motion at different lung volumes compared","volume":"121","author":"Lens","year":"2016","journal-title":"Radiother Oncol"},{"issue":"12","key":"10.1016\/j.adro.2024.101563_bib0032","first-page":"2058","article-title":"Respiratory gating techniques for optimization of lung cancer radiotherapy","volume":"6","author":"Giraud","year":"2011","journal-title":"J Thorac Oncol Off Publ Int Assoc Study Lung Cancer"},{"issue":"3","key":"10.1016\/j.adro.2024.101563_bib0033","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.radonc.2015.11.004","article-title":"Geometric uncertainties in voluntary deep inspiration breath hold radiotherapy for locally advanced lung cancer","volume":"118","author":"Josipovic","year":"2016","journal-title":"Radiother Oncol"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0034","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ijrobp.2010.05.038","article-title":"The use of the active breathing coordinator throughout radical Non\u2013Small-Cell Lung Cancer (NSCLC) radiotherapy","volume":"81","author":"Brock","year":"2011","journal-title":"Int J Radiat Oncol"},{"issue":"5","key":"10.1016\/j.adro.2024.101563_bib0035","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1080\/0284186X.2020.1856408","article-title":"Visually guided inspiration breath-hold facilitated with nasal high flow therapy in locally advanced lung cancer","volume":"60","author":"Peeters","year":"2021","journal-title":"Acta Oncol"},{"key":"10.1016\/j.adro.2024.101563_bib0036","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.phro.2022.04.004","article-title":"Intrafraction target shift comparison using two breath-hold systems in lung stereotactic body radiotherapy","volume":"22","author":"Prado","year":"2022","journal-title":"Phys Imaging Radiat Oncol"},{"issue":"12","key":"10.1016\/j.adro.2024.101563_bib0037","doi-asserted-by":"crossref","first-page":"5525","DOI":"10.1002\/mp.13195","article-title":"Reproducibility of the lung anatomy under active breathing coordinator control: Dosimetric consequences for scanned proton treatments","volume":"45","author":"Den Otter","year":"2018","journal-title":"Med Phys"},{"key":"10.1016\/j.adro.2024.101563_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2023.109887","article-title":"Repeated deep-inspiration breath-hold CT scans at planning underestimate the actual motion between breath-holds at treatment for lung cancer and lymphoma patients","volume":"188","author":"Hoffmann","year":"2023","journal-title":"Radiother Oncol"},{"issue":"2","key":"10.1016\/j.adro.2024.101563_bib0039","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ijrobp.2015.06.011","article-title":"Continuous positive airway pressure for motion management in stereotactic body radiation therapy to the lung: a controlled pilot study","volume":"93","author":"Goldstein","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"10.1016\/j.adro.2024.101563_bib0040","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.ijrobp.2021.03.044","article-title":"Benefits of continuous positive airway pressure (CPAP) during radiation therapy: a prospective Trial","volume":"110","author":"Jacobson","year":"2021","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.adro.2024.101563_bib0041","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.canrad.2022.05.001","article-title":"Deep inspiratory breath hold assisted by continuous positive airway pressure ventilation for lung stereotactic body radiotherapy","volume":"27","author":"Appel","year":"2023","journal-title":"Cancer\/Radioth\u00e9rapie"},{"issue":"6","key":"10.1016\/j.adro.2024.101563_bib0042","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1002\/mp.16403","article-title":"Accuracy of abdominal organ motion estimation in radiotherapy using the right hemidiaphragm top as a surrogate during prolonged breath-holds quantified with MRI","volume":"50","author":"Veldman","year":"2023","journal-title":"Med Phys"},{"issue":"4","key":"10.1016\/j.adro.2024.101563_bib0043","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.ijrobp.2014.07.028","article-title":"Is diaphragm motion a good surrogate for liver tumor motion?","volume":"90","author":"Yang","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245210942400126X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245210942400126X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T02:56:24Z","timestamp":1728528984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S245210942400126X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":43,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S245210942400126X"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2024.101563","relation":{},"ISSN":["2452-1094"],"issn-type":[{"value":"2452-1094","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lung and Liver Stereotactic Body Radiation Therapy During Mechanically Assisted Deep Inspiration Breath-Holds: A Prospective Feasibility Trial","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2024.101563","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"101563"}}