{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:36:52Z","timestamp":1791581812692,"version":"4.3.4"},"reference-count":21,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","advancesradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.adro.2024.101565","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T06:20:50Z","timestamp":1720506050000},"page":"101565","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Stem Cell Therapy Using Bone Marrow-Derived Muse Cells Repairs Radiation-Induced Intestinal Injury Through Their Intestine-Homing via Sphingosine Monophosphate-Sphingosine Monophosphate Receptor 2 Interaction"],"prefix":"10.1016","volume":"9","author":[{"given":"Taichi","family":"Miura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Kado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotoshi","family":"Takiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuko","family":"Kawano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asako","family":"Yamagiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Nishihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiaki","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.adro.2024.101565_bib0001","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1515\/reveh-2021-0108","article-title":"Modulation of radiation-induced intestinal injury by radioprotective agents: A cellular and molecular perspectives","volume":"38","author":"Meena","year":"2023","journal-title":"Rev Environ Health"},{"key":"10.1016\/j.adro.2024.101565_bib0002","doi-asserted-by":"crossref","first-page":"8639","DOI":"10.1073\/pnas.0911647107","article-title":"Unique multipotent cells in adult human mesenchymal cell populations","volume":"107","author":"Kuroda","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.adro.2024.101565_bib0003","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.3390\/cells12131676","article-title":"Multilineage differentiating stress enduring (Muse) Cells: A new era of stem cell-based therapy","volume":"12","author":"Alanazi","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.adro.2024.101565_bib0004","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/nprot.2013.076","article-title":"Isolation, culture and evaluation of multilineage-differentiating stress-enduring (Muse) cells","volume":"8","author":"Kuroda","year":"2013","journal-title":"Nat Protoc"},{"key":"10.1016\/j.adro.2024.101565_bib0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/978-4-431-56847-6_3","article-title":"Muse cells are endogenous reparative stem cells","volume":"1103","author":"Kushida","year":"2018","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.adro.2024.101565_bib0006","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1161\/CIRCRESAHA.117.311648","article-title":"S1P-S1PR2 axis mediates homing of muse cells into damaged heart for long-lasting tissue repair and functional recovery after acute myocardial infarction","volume":"122","author":"Yamada","year":"2018","journal-title":"Circ Res"},{"key":"10.1016\/j.adro.2024.101565_bib0007","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1186\/s13287-023-03425-1","article-title":"Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration","volume":"14","author":"Dushime","year":"2023","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.adro.2024.101565_bib0008","first-page":"83","article-title":"Strong radioprotective FGF1 signaling down-regulates proliferative and metastatic capabilities of the angiosarcoma cell line, ISOS-1, through the dual inhibition of EGFR and VEGFR pathways","volume":"7","author":"Miura","year":"2017","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.adro.2024.101565_bib0009","article-title":"High-sulfated hyaluronic acid ameliorates radiation-induced intestinal damage without blood anticoagulation","volume":"7","author":"Miura","year":"2022","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.adro.2024.101565_bib0010","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1098\/rstb.1998.0246","article-title":"Stem cells in gastrointestinal epithelium: Numbers, characteristics and death","volume":"353","author":"Potten","year":"1998","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.adro.2024.101565_bib0011","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3109\/00365521.2013.772227","article-title":"Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model","volume":"48","author":"Cai","year":"2013","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.adro.2024.101565_bib0012","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1038\/bjc.1997.249","article-title":"Pretreatment with transforming growth factor beta-3 protects small intestinal stem cells against radiation damage in vivo","volume":"75","author":"Potten","year":"1997","journal-title":"Br J Cancer"},{"key":"10.1016\/j.adro.2024.101565_bib0013","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1042\/CS20220392","article-title":"Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell-derived Wnt3","volume":"137","author":"Liu","year":"2023","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.adro.2024.101565_bib0014","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1038\/onc.2009.451","article-title":"Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K\/AKT\/p53 axis","volume":"29","author":"Qiu","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.adro.2024.101565_bib0015","doi-asserted-by":"crossref","first-page":"ar40","DOI":"10.1091\/mbc.E21-02-0089","article-title":"CNOT3 interacts with the Aurora B and MAPK\/ERK kinases to promote survival of differentiating mesendodermal progenitor cells","volume":"32","author":"Sarkar","year":"2021","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.adro.2024.101565_bib0016","doi-asserted-by":"crossref","first-page":"588","DOI":"10.2183\/pjab.86.588","article-title":"The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine","volume":"86","author":"Nakamura","year":"2010","journal-title":"Proc Jpn Acad Ser B Phys Biol Sci"},{"key":"10.1016\/j.adro.2024.101565_bib0017","first-page":"1975","article-title":"Transforming growth factor-beta1, -beta2, and -beta3 in vivo: Effects on normal and mitomycin C-modulated conjunctival scarring","volume":"40","author":"Cordeiro","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.adro.2024.101565_bib0018","doi-asserted-by":"crossref","first-page":"F1216","DOI":"10.1152\/ajprenal.00220.2012","article-title":"Interleukin-11 protects against renal ischemia and reperfusion injury","volume":"303","author":"Lee","year":"2012","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.adro.2024.101565_bib0019","doi-asserted-by":"crossref","first-page":"e12897","DOI":"10.1111\/sji.12897","article-title":"Potential methods for improving the efficacy of mesenchymal stem cells in the treatment of inflammatory bowel diseases","volume":"92","author":"Zhang","year":"2020","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.adro.2024.101565_bib0020","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1038\/aps.2009.133","article-title":"Hepatocyte growth factor protects endothelial cells against gamma ray irradiation-induced damage","volume":"30","author":"Hu","year":"2009","journal-title":"Acta Pharmacol Sin"},{"key":"10.1016\/j.adro.2024.101565_bib0021","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.3390\/ijms22042064","article-title":"Why do Muse stem cells present an enduring stress capacity? hints from a comparative proteome analysis","volume":"22","author":"Acar","year":"2021","journal-title":"Int J Mol Sci"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109424001283?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109424001283?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T17:51:00Z","timestamp":1728323460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452109424001283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S2452109424001283"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2024.101565","relation":{},"ISSN":["2452-1094"],"issn-type":[{"value":"2452-1094","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stem Cell Therapy Using Bone Marrow-Derived Muse Cells Repairs Radiation-Induced Intestinal Injury Through Their Intestine-Homing via Sphingosine Monophosphate-Sphingosine Monophosphate Receptor 2 Interaction","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2024.101565","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"101565"}}