{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:17:02Z","timestamp":1791335822032,"version":"4.3.1"},"reference-count":11,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007313","name":"University of Texas MD Anderson Cancer Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007313","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","advancesradonc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.adro.2024.101697","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T16:44:06Z","timestamp":1733157846000},"page":"101697","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis From Solid Tumors"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4480-2801","authenticated-orcid":false,"given":"Keng","family":"Lam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis F.","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clark R.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn E.","family":"Marqueen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas H.","family":"Beckham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazanin K.","family":"Majd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley E.","family":"Aaroe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Loghin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara J.","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"McGovern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.adro.2024.101697_bib0001","doi-asserted-by":"crossref","first-page":"685","DOI":"10.3390\/cancers15030685","article-title":"The evolving landscape of leptomeningeal cancer from solid tumors: a systematic review of clinical trials","volume":"15","author":"Marenco-Hillembrand","year":"2023","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.adro.2024.101697_bib0002","doi-asserted-by":"crossref","first-page":"371","DOI":"10.4274\/ejbh.galenos.2021.2021-4-10","article-title":"Assessment of leptomeningeal carcinomatosis diagnosis, management and outcomes in patients with solid tumors over a decade of experience","volume":"17","author":"Rinehardt","year":"2021","journal-title":"Eur J Breast Health"},{"key":"10.1016\/j.adro.2024.101697_bib0003","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1200\/JCO.22.01148","article-title":"Randomized phase II trial of proton craniospinal irradiation versus photon involved-field radiotherapy for patients with solid tumor leptomeningeal metastasis","volume":"40","author":"Yang","year":"2022","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.adro.2024.101697_bib0004","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1748-717X-8-32","article-title":"Standardized treatment planning methodology for passively scattered proton craniospinal irradiation","volume":"8","author":"Giebeler","year":"2013","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.adro.2024.101697_bib0005","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/0956797613504966","article-title":"The new statistics: why and how","volume":"25","author":"Cumming","year":"2014","journal-title":"Psychol Sci"},{"key":"10.1016\/j.adro.2024.101697_bib0006","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2147\/CMAR.S182154","article-title":"Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis","volume":"11","author":"El Shafie","year":"2019","journal-title":"Cancer Manag Res"},{"key":"10.1016\/j.adro.2024.101697_bib0007","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1186\/s12885-020-06984-1","article-title":"Craniospinal irradiation (CSI) in patients with leptomeningeal metastases: risk-benefit-profile and development of a prognostic score for decision making in the palliative setting","volume":"20","author":"Devecka","year":"2020","journal-title":"BMC Cancer"},{"key":"10.1016\/j.adro.2024.101697_bib0008","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3389\/fonc.2018.00641","article-title":"palliative radiotherapy for leptomeningeal carcinomatosis-analysis of outcome, prognostic factors, and symptom response","volume":"8","author":"El Shafie","year":"2018","journal-title":"Front Oncol"},{"key":"10.1016\/j.adro.2024.101697_bib0009","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.ijrobp.2013.01.014","article-title":"Proton beam craniospinal irradiation reduces acute toxicity for adults with medulloblastoma","volume":"86","author":"Brown","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.adro.2024.101697_bib0010","article-title":"Proton versus photon craniospinal irradiation for adult medulloblastoma: A dosimetric, toxicity, and exploratory cost analysis","volume":"6","author":"Breen","year":"2024","journal-title":"Neurooncol Adv"},{"key":"10.1016\/j.adro.2024.101697_bib0011","first-page":"1","article-title":"Emerging systemic treatment perspectives on brain metastases: moving toward a better outlook for patients","volume":"42","author":"Alvarez-Breckenridge","year":"2022","journal-title":"Am Soc Clin Oncol Educ Book"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109424002604?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109424002604?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T22:15:10Z","timestamp":1740867310000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452109424002604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S2452109424002604"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2024.101697","relation":{},"ISSN":["2452-1094"],"issn-type":[{"value":"2452-1094","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis From Solid Tumors","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2024.101697","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"101697"}}