{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:08:00Z","timestamp":1789124880458,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["advancesradonc.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Radiation Oncology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.adro.2026.102105","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:26:50Z","timestamp":1789122410000},"page":"102105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low-Dose Radiation Therapy in Treatment of Recalcitrant Hidradenitis Suppurativa"],"prefix":"10.1016","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3735-0760","authenticated-orcid":false,"given":"Robert L.","family":"Walker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhrarup","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarini","family":"Saksena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilanjan","family":"Haldar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dane","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1907-7828","authenticated-orcid":false,"given":"Gregory S.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.adro.2026.102105_bib0001","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jid.2017.09.008","article-title":"Increased suicide risk in patients with hidradenitis suppurativa","volume":"138","author":"Thorlacius","year":"2018","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0002","series-title":"Dermatologic Surgery: Principles and Practice","first-page":"729","article-title":"Axillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: surgical approach","author":"Hurley","year":"1989"},{"key":"10.1016\/j.adro.2026.102105_bib0003","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0140-6736(25)01444-8","article-title":"Hidradenitis suppurativa: Complexity in pathogenesis and management","volume":"406","author":"Campbell","year":"2025","journal-title":"Lancet"},{"key":"10.1016\/j.adro.2026.102105_bib0004","doi-asserted-by":"crossref","first-page":"7240","DOI":"10.3390\/jcm11237240","article-title":"Current medical and surgical treatment of hidradenitis suppurativa\u2014A comprehensive review","volume":"11","author":"Ocker","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.adro.2026.102105_bib0005","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jaad.2020.09.039","article-title":"Pain management in hidradenitis suppurativa and a proposed treatment algorithm","volume":"85","author":"Savage","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0006","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1159\/000531926","article-title":"Resorcinol 10% as a promising therapeutic option for mild hidradenitis suppurativa: a prospective, randomized, open study","volume":"9","author":"Katoulis","year":"2023","journal-title":"Skin Appendage Disord"},{"key":"10.1016\/j.adro.2026.102105_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaad.2023.12.050","article-title":"Punch debridement (mini-deroofing): An in-office surgical option for hidradenitis suppurativa","volume":"90","author":"Mansour","year":"2024","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0008","article-title":"Effectiveness of surgical deroofing and carbon dioxide laser in moderate-to-severe hidradenitis suppurativa patients","volume":"16","author":"Clark","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.adro.2026.102105_bib0009","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1056\/NEJMoa1504370","article-title":"Two phase 3 trials of adalimumab for hidradenitis suppurativa","volume":"375","author":"Kimball","year":"2016","journal-title":"N Engl J Med"},{"issue":"5 suppl 1","key":"10.1016\/j.adro.2026.102105_bib0010","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/j.jaad.2015.07.044","article-title":"Recurrence of hidradenitis suppurativa after surgical management: A systematic review and meta-analysis","volume":"73","author":"Mehdizadeh","year":"2015","journal-title":"J Am Acad Dermatol."},{"key":"10.1016\/j.adro.2026.102105_bib0011","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1111\/j.1365-2133.2008.08932.x","article-title":"Outcomes of treatment of nine cases of recalcitrant severe hidradenitis suppurativa with carbon dioxide laser","volume":"159","author":"Madan","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0012","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.prro.2025.01.008","article-title":"Radiation therapy in the management of hidradenitis suppurativa","volume":"15","author":"Myers","year":"2025","journal-title":"Pract Radiat Oncol."},{"key":"10.1016\/j.adro.2026.102105_bib0013","first-page":"286","article-title":"Strahlentherapie der Hidradenitis axillaris\u2013heute noch aktuell? [Radiotherapy of hidradenitis suppurativa \u2013 still valid today?]","volume":"176","author":"Fr\u00f6hlich","year":"2000","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.adro.2026.102105_bib0014","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1159\/000514027","article-title":"Radiotherapy for hidradenitis suppurativa: A systematic review","volume":"237","author":"Thompson","year":"2021","journal-title":"Dermatology"},{"key":"10.1016\/j.adro.2026.102105_bib0015","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3857\/roj.2021.00570","article-title":"Radiation therapy in chronic hidradenitis suppurativa: case report","volume":"40","author":"Sakyanun","year":"2022","journal-title":"Radiat Oncol J"},{"key":"10.1016\/j.adro.2026.102105_bib0016","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1001\/archderm.1965.01600180082016","article-title":"Temporary x-ray epilation therapy of chronic axillary hidradenitis suppurativa","volume":"92","author":"Zeligman","year":"1965","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0017","doi-asserted-by":"crossref","first-page":"16","DOI":"10.5070\/D30JJ6W1DT","article-title":"The role of radiotherapy in the treatment of hidradenitis suppurativa: case report and review of the literature","volume":"16","author":"Trombetta","year":"2010","journal-title":"Dermatol Online J"},{"key":"10.1016\/j.adro.2026.102105_bib0018","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1159\/000517252","article-title":"Long-term follow-up after radiotherapy of hidradenitis suppurativa","volume":"238","author":"Boer","year":"2022","journal-title":"Dermatology"},{"key":"10.1016\/j.adro.2026.102105_bib0019","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1148\/54.1.74","article-title":"Hidradenitis suppurativa axillaris; an analysis of 54 cases treated with roentgen rays","volume":"54","author":"Schenck","year":"1950","journal-title":"Radiology"},{"key":"10.1016\/j.adro.2026.102105_bib0020","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.jaad.2014.09.012","article-title":"Hidradenitis suppurativa is a systemic disease with substantial comorbidity burden: A chart-verified case-control analysis","volume":"71","author":"Shlyankevich","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.adro.2026.102105_bib0021","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1097\/00007611-199404000-00028","article-title":"Hidradenitis in a patient with AIDS: Palliation with superficial radiation","volume":"87","author":"Johnson","year":"1994","journal-title":"South Med J"},{"issue":"suppl 1","key":"10.1016\/j.adro.2026.102105_bib0022","doi-asserted-by":"crossref","first-page":"S358","DOI":"10.1016\/j.rpor.2013.03.572","article-title":"Radiation therapy for refractory hidradenitis suppurativa","volume":"18","author":"Garcia-Grande","year":"2013","journal-title":"Rep Pract Oncol Radiother."},{"key":"10.1016\/j.adro.2026.102105_bib0023","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4172\/2155-9619.1000146","article-title":"Radiation therapy for chronic hidradenitis suppurativa","volume":"4","author":"Patel","year":"2013","journal-title":"J Nucl Med Radiat Ther"},{"key":"10.1016\/j.adro.2026.102105_bib0024","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/dth.12393","article-title":"Successful use of brachytherapy for a severe hidradenitis suppurativa variant","volume":"29","author":"Paul","year":"2016","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.adro.2026.102105_bib0027","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0140-6736(23)00022-3","article-title":"Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): Week 16 and week 52 results of two identical, multicentre, randomised, placebo-controlled, double-blind phase 3 trials","volume":"401","author":"Kimball","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.adro.2026.102105_bib0028","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S0140-6736(24)02475-9","article-title":"Hidradenitis suppurativa","volume":"405","author":"Sabat","year":"2025","journal-title":"Lancet"},{"key":"10.1016\/j.adro.2026.102105_bib0029","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2020-238848","article-title":"Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa","volume":"13","author":"Rozati","year":"2020","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.adro.2026.102105_bib0030","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2024.2382372","article-title":"A state-of-the-art systematic review of cancer in hidradenitis suppurativa","volume":"56","author":"Abu Rached","year":"2024","journal-title":"Ann Med"}],"container-title":["Advances in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109426001120?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452109426001120?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:27:05Z","timestamp":1789122425000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452109426001120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S2452109426001120"],"URL":"https:\/\/doi.org\/10.1016\/j.adro.2026.102105","relation":{},"ISSN":["2452-1094"],"issn-type":[{"value":"2452-1094","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-Dose Radiation Therapy in Treatment of Recalcitrant Hidradenitis Suppurativa","name":"articletitle","label":"Article Title"},{"value":"Advances in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.adro.2026.102105","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of American Society for Radiation Oncology.","name":"copyright","label":"Copyright"}],"article-number":"102105"}}