{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:18:07Z","timestamp":1791026287516,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.ahj.2008.03.010","type":"journal-article","created":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T04:25:31Z","timestamp":1214627131000},"page":"57-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":179,"title":["Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age &gt;75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme"],"prefix":"10.1016","volume":"156","author":[{"given":"Stephan","family":"Rietbrock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Heeley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Plumb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tjeerd","family":"van Staa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2008.03.010_bib1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1161\/01.STR.22.8.983","article-title":"Atrial fibrillation as an independent risk factor for stroke: the Framingham Study","volume":"22","author":"Wolf","year":"1991","journal-title":"Stroke"},{"key":"10.1016\/j.ahj.2008.03.010_bib2","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/bmj.39456.688333.BE","article-title":"Impact of functional status at six months on long term survival in patients with ischaemic stroke: prospective cohort studies","volume":"366","author":"Slot","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2008.03.010_bib3","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1159\/000068743","article-title":"Atrial fibrillation is associated with severe acute ischemic stroke","volume":"22","author":"Dulli","year":"2003","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.ahj.2008.03.010_bib4","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1161\/01.STR.30.4.724","article-title":"Predictors of acute hospital costs for treatment of ischemic stroke in an academic center","volume":"30","author":"Diringer","year":"1999","journal-title":"Stroke"},{"key":"10.1016\/j.ahj.2008.03.010_bib5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.thromres.2005.08.007","article-title":"Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysis","volume":"118","author":"Lip","year":"2006","journal-title":"Thromb Res."},{"key":"10.1016\/j.ahj.2008.03.010_bib6","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1161\/circ.114.4.257","volume":"114","author":"Fuster","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2008.03.010_bib7","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1161\/01.CIR.0000145172.55640.93","article-title":"Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin","volume":"110","author":"Gage","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2008.03.010_bib8","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1001\/jama.285.22.2864","article-title":"Validation of clinical classification schemes for predicting stroke: results from the national registry of atrial fibrillation","volume":"285","author":"Gage","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2008.03.010_bib9","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1161\/STROKEAHA.106.477133","article-title":"Can patients at elevated risk of stroke treated with anticoagulants be further risk stratified","volume":"38","author":"Baruch","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.ahj.2008.03.010_bib10","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0140-6736(97)04248-7","article-title":"The UK General Practice Research Database","volume":"350","author":"Walley","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2008.03.010_bib11","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0895-4356(01)00478-4","article-title":"Incidence of chronic atrial fibrillation in general practice and its treatment pattern","volume":"55","author":"Ruig\u00f3mez","year":"2002","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ahj.2008.03.010_bib13","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4","article-title":"Multivariate prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors","volume":"15","author":"Harrell","year":"1996","journal-title":"Stats Med"},{"key":"10.1016\/j.ahj.2008.03.010_bib14","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0002-8703(83)90208-9","article-title":"Coronary heart disease and atrial fibrillation: the Framingham study","volume":"106","author":"Kannel","year":"1983","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2008.03.010_bib15","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/eurheartj\/ehi825","article-title":"Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study","volume":"27","author":"Heeringa","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2008.03.010_bib16","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1212\/WNL.28.10.973","article-title":"Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study","volume":"28","author":"Wolf","year":"1978","journal-title":"Neurology"},{"key":"10.1016\/j.ahj.2008.03.010_bib17","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0140-6736(87)90174-7","article-title":"Risk of stroke in non-rheumatic atrial fibrillation","volume":"1","author":"Flegel","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2008.03.010_bib18","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1001\/archinte.1994.00420130036007","article-title":"Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation","volume":"154","author":"Atrial Fibrillation Investigators","year":"1994","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ahj.2008.03.010_bib19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S1052-3057(10)80166-1","article-title":"Risk factors for thromboembolism during aspirin therapy in patients with atrial fibrillation: the Stroke Prevention in Atrial Fibrillation study","volume":"5","author":"Stroke Prevention in Atrial Fibrillation Investigators","year":"1995","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1016\/j.ahj.2008.03.010_bib20","doi-asserted-by":"crossref","first-page":"194S","DOI":"10.1378\/chest.119.1_suppl.194S","article-title":"Antithrombotic therapy in atrial fibrillation","volume":"119","author":"Albers","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.ahj.2008.03.010_bib21","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1001\/jama.290.8.1049","article-title":"A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study","volume":"290","author":"Wang","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2008.03.010_bib22","first-page":"936","article-title":"Echocardiographic predictors of stroke in patients with atrial fibrillation: a prospective study of 1066 patients from 3 clinical trials","volume":"163","author":"Atrial Fibrillation Investigators","year":"1998","journal-title":"Arch Itern Med"},{"key":"10.1016\/j.ahj.2008.03.010_bib23","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S0002-9343(99)80348-9","article-title":"The natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba follow-up study","volume":"98","author":"Krahn","year":"1995","journal-title":"Am J Med"},{"key":"10.1016\/j.ahj.2008.03.010_bib24","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1212\/01.wnl.0000267275.68538.8d","article-title":"The stroke risk in atrial fibrillation working group. Independent predictors of stroke in patients with atrial fibrillation: a systematic review","volume":"69","year":"2007","journal-title":"Neurology"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870308001968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870308001968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:35:39Z","timestamp":1757568939000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870308001968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S0002870308001968"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2008.03.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1137964.595069","asserted-by":"object"}]},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2008.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}