{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:20:12Z","timestamp":1791638412442,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.ahj.2009.04.004","type":"journal-article","created":{"date-parts":[[2009,5,22]],"date-time":"2009-05-22T06:57:17Z","timestamp":1242975437000},"page":"1097-1105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Validity of a risk-prediction tool for hospital mortality: The Global Registry of Acute Coronary Events"],"prefix":"10.1016","volume":"157","author":[{"given":"Karen S.","family":"Pieper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M.","family":"Gore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"FitzGerald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher B.","family":"Granger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Steg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim A.","family":"Eagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick A.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Budaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.A.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2009.04.004_bib1","first-page":"e148","volume":"116","author":"Anderson","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jacc.2007.10.001","article-title":"2007 focused update of the ACC\/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"51","author":"Antman","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2009.04.004_bib3","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","article-title":"Universal definition of myocardial infarction","volume":"116","author":"Thygesen","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1136\/hrt.2005.084830","article-title":"Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE)","volume":"93","author":"Fox","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.ahj.2009.04.004_bib5","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.ahj.2007.01.001","article-title":"Use of proven therapies in non\u2013ST-elevation acute coronary syndromes according to evidence-based risk stratification","volume":"153","author":"Oliveira","year":"2007","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib6","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1001\/archinte.165.16.1870","article-title":"Relationship between risk stratification by cardiac troponin level and adherence to guidelines for non\u2013ST-segment elevation acute coronary syndromes","volume":"165","author":"Roe","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ahj.2009.04.004_bib7","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1067\/mhj.2001.112404","article-title":"Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes","volume":"141","author":"The GRACE Investigators","year":"2001","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib8","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1001\/archinte.163.19.2345","article-title":"Predictors of hospital mortality in the Global Registry of Acute Coronary Events","volume":"163","author":"Granger","year":"2003","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ahj.2009.04.004_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ahj.2005.07.013","article-title":"Evaluating the performance of the Global Registry of Acute Coronary Events risk-adjustment index across socioeconomic strata among patients discharged from the hospital after acute myocardial infarction","volume":"151","author":"Alter","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib10","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1136\/hrt.2005.073122","article-title":"Validity of the GRACE (Global Registry of Acute Coronary Events) acute coronary syndrome prediction model for six month post-discharge death in an independent data set","volume":"92","author":"Bradshaw","year":"2006","journal-title":"Heart"},{"key":"10.1016\/j.ahj.2009.04.004_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/qjmed\/hcl133","article-title":"Risk prediction in patients presenting with suspected cardiac pain: the GRACE and TIMI risk scores versus clinical evaluation","volume":"100","author":"Ramsay","year":"2007","journal-title":"QJM"},{"key":"10.1016\/j.ahj.2009.04.004_bib12","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1093\/eurheartj\/ehi187","article-title":"TIMI, PURSUIT, and GRACE risk scores: sustained prognostic value and interaction with revascularization in NSTE-ACS","volume":"26","author":"de Araujo Goncalves","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib13","series-title":"Statistical Computing Section","first-page":"45","article-title":"Additive splines in statistics","author":"Stone","year":"1985"},{"key":"10.1016\/j.ahj.2009.04.004_bib14","series-title":"Regression modeling strategies with applications to linear models, logistic regression and survival analysis","author":"Harrell","year":"2001"},{"key":"10.1016\/j.ahj.2009.04.004_bib15","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1001\/jama.284.7.835","article-title":"The TIMI risk score for unstable angina\/non\u2013ST elevation MI: a method for prognostication and therapeutic decision making","volume":"284","author":"Antman","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2009.04.004_bib16","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1161\/01.CIR.102.17.2031","article-title":"TIMI risk score for ST-elevation myocardial infarction: a convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy","volume":"102","author":"Morrow","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib17","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1161\/CIRCULATIONAHA.106.672402","article-title":"Use and misuse of the receiver operating characteristic curve in risk prediction","volume":"115","author":"Cook","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib18","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/eurheartj\/ehm161","article-title":"Guidelines for the diagnosis and treatment of non\u2013ST-segment elevation acute coronary syndromes","volume":"28","author":"Bassand","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib19","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S0002-8703(97)70164-9","article-title":"Selection of thrombolytic therapy for individual patients: development of a clinical model. GUSTO-I Investigators","volume":"133","author":"Califf","year":"1997","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2009.04.004_bib20","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1161\/01.CIR.101.22.2557","article-title":"Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Invetigators","volume":"101","author":"Boersma","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib21","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1161\/01.CIR.91.6.1659","article-title":"Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators","volume":"91","author":"Lee","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2009.04.004_bib22","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1093\/eurheartj\/ehm161","article-title":"Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes","volume":"28","author":"Bassand","year":"2007","journal-title":"Eur Heart J"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870309002725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870309002725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:38:37Z","timestamp":1757569117000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870309002725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0002870309002725"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2009.04.004","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Validity of a risk-prediction tool for hospital mortality: The Global Registry of Acute Coronary Events","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2009.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}