{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:07:35Z","timestamp":1793138855303,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.ahj.2014.03.003","type":"journal-article","created":{"date-parts":[[2014,3,21]],"date-time":"2014-03-21T01:19:25Z","timestamp":1395364765000},"page":"796-803.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":135,"title":["PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial"],"prefix":"10.1016","volume":"167","clinical-trial-number":[{"clinical-trial-number":"nct01174550","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Pamela S.","family":"Douglas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udo","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry L.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel B.","family":"Mark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein R.","family":"Al-Khalidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Anstrom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowena J.","family":"Dolor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Kosinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell W.","family":"Krucoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel W.","family":"Mudrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manesh R.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Picard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Udelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Velazquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawton","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ahj.2014.03.003_bb0005","first-page":"e6","article-title":"Heart disease and stroke statistics\u20142013 update: a report from the American Heart Association","volume":"127","author":"Go","year":"2013","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ahj.2014.03.003_bb0010","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0196-0644(97)70298-1","article-title":"An evaluation of technologies for identifying acute cardiac ischemia in the emergency department: a report from a National Heart Attack Alert Program Working Group","volume":"29","author":"Selker","year":"1997","journal-title":"Ann Emerg Med"},{"issue":"24","key":"10.1016\/j.ahj.2014.03.003_bb0015","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1016\/j.jacc.2012.07.013","volume":"60","author":"Fihn","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.ahj.2014.03.003_bb0020","first-page":"1","article-title":"Non-invasive cardiac imaging technologies for the diagnosis of coronary artery disease: a summary of evidence-based analyses","volume":"10","year":"2010","journal-title":"Ont Health Technol Assess Ser"},{"issue":"7","key":"10.1016\/j.ahj.2014.03.003_bb0025","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jcmg.2010.05.004","article-title":"Why all the focus on cardiac imaging?","volume":"3","author":"Shaw","year":"2010","journal-title":"JACC Cardiovasc Imaging"},{"issue":"10","key":"10.1016\/j.ahj.2014.03.003_bb0030","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/jama.280.10.913","article-title":"Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance","volume":"280","author":"Fleischmann","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2014.03.003_bb0035","doi-asserted-by":"crossref","unstructured":"Mowatt G, Vale L, Brazzelli M, et al. Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction. Health Technol Assess. 2004;8(30):iii-iv, 1-207.","DOI":"10.3310\/hta8300"},{"issue":"3","key":"10.1016\/j.ahj.2014.03.003_bb0040","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.ahj.2011.11.022","article-title":"Downstream procedures and outcomes after stress testing for chest pain without known coronary artery disease in the United States","volume":"163","author":"Mudrick","year":"2012","journal-title":"Am Heart J"},{"issue":"10","key":"10.1016\/j.ahj.2014.03.003_bb0045","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.jacc.2012.11.056","article-title":"Temporal trends in the frequency of inducible myocardial ischemia during cardiac stress testing: 1991 to 2009","volume":"61","author":"Rozanski","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.ahj.2014.03.003_bb0050","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1056\/NEJMoa0907272","article-title":"Low diagnostic yield of elective coronary angiography","volume":"362","author":"Patel","year":"2010","journal-title":"N Engl J Med"},{"issue":"26","key":"10.1016\/j.ahj.2014.03.003_bb0055","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1056\/NEJMhpr061219","article-title":"The new era of medical imaging\u2014progress and pitfalls","volume":"354","author":"Iglehart","year":"2006","journal-title":"N Engl J Med"},{"issue":"12","key":"10.1016\/j.ahj.2014.03.003_bb0060","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.jcmg.2012.10.007","article-title":"From adequate evidence to optimal evidence","volume":"5","author":"Shaw","year":"2012","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.ahj.2014.03.003_bb0065","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1016\/j.jacc.2008.07.031","volume":"52","author":"Budoff","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2014.03.003_bb0070","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.jacc.2008.08.058","article-title":"Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study","volume":"52","author":"Meijboom","year":"2008","journal-title":"J Am Coll Cardiol"},{"issue":"22","key":"10.1016\/j.ahj.2014.03.003_bb0075","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1056\/NEJMoa0806576","article-title":"Diagnostic performance of coronary angiography by 64-row CT","volume":"359","author":"Miller","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2014.03.003_bb0080","doi-asserted-by":"crossref","first-page":"167","DOI":"10.7326\/0003-4819-152-3-201002020-00008","article-title":"Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging","author":"Schuetz","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ahj.2014.03.003_bb0085","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/CIRCIMAGING.110.955351","article-title":"Prognostic value of coronary computed tomographic angiography in comparison with calcium scoring and clinical risk scores","author":"Hadamitzky","year":"2011","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.ahj.2014.03.003_bb0090","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1016\/j.jacc.2010.12.043","article-title":"Meta-analysis and systematic review of the long-term predictive value of assessment of coronary atherosclerosis by contrast-enhanced coronary computed tomography angiography","volume":"57","author":"Bamberg","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2014.03.003_bb0095","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.jacc.2010.10.011","article-title":"Prognostic value of cardiac computed tomography angiography: a systematic review and meta-analysis","author":"Hulten","year":"2011","journal-title":"J Am Coll Cardiol"},{"issue":"19","key":"10.1016\/j.ahj.2014.03.003_bb0100","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1001\/jama.2011.1652","article-title":"Association of coronary CT angiography or stress testing with subsequent utilization and spending among Medicare beneficiaries","volume":"306","author":"Shreibati","year":"2011","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.ahj.2014.03.003_bb0105","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1056\/NEJMoa0807611","article-title":"Fractional flow reserve versus angiography for guiding percutaneous coronary intervention","volume":"360","author":"Tonino","year":"2009","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.ahj.2014.03.003_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/CIRCIMAGING.108.841429","article-title":"CT angiography: first things first","volume":"2","author":"Lauer","year":"2009","journal-title":"Circ Cardiovasc Imaging"},{"issue":"7","key":"10.1016\/j.ahj.2014.03.003_bb0115","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jcmg.2009.01.018","article-title":"Outcomes research in cardiovascular imaging: report of a workshop sponsored by the National Heart, Lung, and Blood Institute","volume":"2","author":"Douglas","year":"2009","journal-title":"JACC Cardiovasc Imaging"},{"issue":"7","key":"10.1016\/j.ahj.2014.03.003_bb0120","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.jacc.2011.12.057","article-title":"Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute","volume":"60","author":"Hlatky","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.ahj.2014.03.003_bb0125","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1177\/1740774512450097","article-title":"The role for pragmatic randomized controlled trials (pRCTs) in comparative effectiveness research","volume":"9","author":"Chalkidou","year":"2012","journal-title":"Clin Trials"},{"issue":"3","key":"10.1016\/j.ahj.2014.03.003_bb0130","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jacc.2007.11.008","article-title":"ACCF 2008 Recommendations for Training in Adult Cardiovascular Medicine Core Cardiology Training (COCATS 3) (revision of the 2002 COCATS Training Statement)","volume":"51","author":"Beller","year":"2008","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.ahj.2014.03.003_bb0135","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.echo.2007.07.003","article-title":"American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography","volume":"20","author":"Pellikka","year":"2007","journal-title":"J Am Soc Echocardiogr"},{"issue":"6","key":"10.1016\/j.ahj.2014.03.003_bb0140","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1016\/j.nuclcard.2007.09.024","article-title":"Instrumentation quality assurance and performance","volume":"14","author":"Nichols","year":"2007","journal-title":"J Nucl Cardiol"},{"issue":"2","key":"10.1016\/j.ahj.2014.03.003_bb0145","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jcct.2009.01.001","article-title":"SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography","volume":"3","author":"Raff","year":"2009","journal-title":"J Cardiovasc Comput Tomogr"},{"issue":"3","key":"10.1016\/j.ahj.2014.03.003_bb0150","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jcct.2009.03.004","article-title":"SCCT guidelines for performance of coronary computed tomographic angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee","volume":"3","author":"Abbara","year":"2009","journal-title":"J Cardiovasc Comput Tomogr"},{"issue":"17","key":"10.1016\/j.ahj.2014.03.003_bb0155","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1002\/sim.1517","article-title":"A global sensitivity analysis of performance of a medical diagnostic test when verification bias is present","volume":"22","author":"Kosinski","year":"2003","journal-title":"Stat Med"},{"issue":"1","key":"10.1016\/j.ahj.2014.03.003_bb0160","first-page":"173","article-title":"Assessing accuracy of a continuous screening test in the presence of verification bias","volume":"54","author":"Alonzo","year":"2005","journal-title":"Journal of the Royal Statistical Society: Series C (Applied Statistics)"},{"issue":"4","key":"10.1016\/j.ahj.2014.03.003_bb0165","doi-asserted-by":"crossref","first-page":"933","DOI":"10.2307\/2533433","article-title":"A random-effects ordinal regression model for multilevel analysis","volume":"50","author":"Hedeker","year":"1994","journal-title":"Biometrics"},{"issue":"2","key":"10.1016\/j.ahj.2014.03.003_bb0170","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/CIRCGENETICS.112.964015","article-title":"A blood-based gene expression test for obstructive coronary artery disease tested in symptomatic nondiabetic patients referred for myocardial perfusion imaging the COMPASS study","volume":"6","author":"Thomas","year":"2013","journal-title":"Circ Cardiovasc Genet"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870314001380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870314001380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:51:54Z","timestamp":1757569914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870314001380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0002870314001380"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2014.03.003","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2014.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Mosby, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}