{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:34:18Z","timestamp":1793144058675,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.ahj.2016.10.015","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T01:32:25Z","timestamp":1477618345000},"page":"71-80","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["The impact of functional vs degenerative mitral regurgitation on clinical outcomes among patients undergoing transcatheter aortic valve implantation"],"prefix":"10.1016","volume":"184","author":[{"given":"Ren\u00e9","family":"Vollenbroich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Stortecky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Praz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Lanz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Franzone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Zuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dik","family":"Heg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Valgimigli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crochan John","family":"O'Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Heinisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Roost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Wenaweser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Windecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pilgrim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2016.10.015_bb0005","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2016.10.015_bb0010","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1161\/CIRCULATIONAHA.113.001822","article-title":"Interplay between mitral regurgitation and transcatheter aortic valve replacement with the CoreValve Revalving System: a multicenter registry","volume":"128","author":"Bedogni","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2016.10.015_bb0015","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.4244\/EIJV8I12A209","article-title":"The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients","volume":"8","author":"Di Mario","year":"2013","journal-title":"EuroIntervention"},{"key":"10.1016\/j.ahj.2016.10.015_bb0020","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus surgical aortic-valve replacement in high-risk patients","volume":"364","author":"Smith","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2016.10.015_bb0025","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1136\/heartjnl-2014-305775","article-title":"Impact of preprocedural mitral regurgitation upon mortality after transcatheter aortic valve implantation (TAVI) for severe aortic stenosis","volume":"100","author":"Khawaja","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.ahj.2016.10.015_bb0030","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.amjcard.2010.04.030","article-title":"Echocardiographic predictors for persistent functional mitral regurgitation after aortic valve replacement in patients with aortic valve stenosis","volume":"106","author":"Matsumura","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0035","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1540-8191.2009.00965.x","article-title":"Is concomitant surgery for moderate functional mitral regurgitation indicated during aortic valve replacement for aortic stenosis? A systematic review and evidence-based recommendations","volume":"25","author":"Alghamdi","year":"2010","journal-title":"J Card Surg"},{"key":"10.1016\/j.ahj.2016.10.015_bb0040","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1540-8175.2010.01284.x","article-title":"Recurrent mitral regurgitation late after annuloplasty for ischemic mitral regurgitation","volume":"28","author":"Shiota","year":"2011","journal-title":"Echocardiography"},{"key":"10.1016\/j.ahj.2016.10.015_bb0045","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/j.jacc.2011.05.063","article-title":"Clinical outcomes of patients with severe aortic stenosis at increased surgical risk according to treatment modality","volume":"58","author":"Wenaweser","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0050","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0894-7317(03)00335-3","article-title":"Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography","volume":"16","author":"Zoghbi","year":"2003","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.ahj.2016.10.015_bb0055","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0140-6736(09)60692-9","article-title":"Mitral regurgitation","volume":"373","author":"Enriquez-Sarano","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2016.10.015_bb0060","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0025-6196(12)61522-5","article-title":"Surgical pathology of the mitral valve: a study of 712 cases spanning 21years","volume":"62","author":"Olson","year":"1987","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.ahj.2016.10.015_bb0065","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/S0735-1097(99)00314-9","article-title":"Functional anatomy of mitral regurgitation: echocardiographic assessment and implications on outcome","volume":"34","author":"Enriquez-Sarano","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0070","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.jacc.2012.09.001","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"60","author":"Kappetein","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0075","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1093\/ejcts\/ezr236","article-title":"Impact of preoperative mitral valve regurgitation on outcomes after transcatheter aortic valve implantation","volume":"41","author":"D'Onofrio","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.ahj.2016.10.015_bb0080","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.jacc.2009.12.014","article-title":"Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience","volume":"55","author":"Rodes-Cabau","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0085","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","article-title":"Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery","volume":"363","author":"Leon","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2016.10.015_bb0090","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.113.001822","article-title":"Interplay between mitral regurgitation and transcatheter aortic valve replacement with the CoreValve Revalving System: a multicenter registry","author":"Bedogni","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2016.10.015_bb0095","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.amjcard.2015.11.064","article-title":"Impact of functional versus organic baseline mitral regurgitation on short- and long-term outcomes after transcatheter aortic valve replacement","volume":"117","author":"Kiramijyan","year":"2016","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0100","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1016\/j.jacc.2012.02.020","article-title":"Transcatheter aortic valve replacement: outcomes of patients with moderate or severe mitral regurgitation","volume":"59","author":"Toggweiler","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0105","first-page":"272","article-title":"Outcome and improvement predictors of mitral regurgitation after transcatheter aortic valve implantation","volume":"20","author":"Durst","year":"2011","journal-title":"J Heart Valve Dis"},{"key":"10.1016\/j.ahj.2016.10.015_bb0110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.athoracsur.2012.08.030","article-title":"Transcatheter aortic valve implantation in patients with concomitant mitral and tricuspid regurgitation","volume":"95","author":"Hutter","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ahj.2016.10.015_bb0115","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1093\/eurheartj\/ehu074","article-title":"Coronary artery disease severity and aortic stenosis: clinical outcomes according to SYNTAX score in patients undergoing transcatheter aortic valve implantation","volume":"35","author":"Stefanini","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2016.10.015_bb0120","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/S0003-4975(00)01968-8","article-title":"Predictors of mortality for patients undergoing cardiac valve replacements in New York State","volume":"70","author":"Hannan","year":"2000","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ahj.2016.10.015_bb0125","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/S0022-5223(02)73225-X","article-title":"Mitral valve repair with aortic valve replacement is superior to double valve replacement","volume":"125","author":"Gillinov","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ahj.2016.10.015_bb0130","doi-asserted-by":"crossref","first-page":"S155","DOI":"10.1161\/CIRCULATIONAHA.108.843573","article-title":"Outcomes of patients undergoing concomitant aortic and mitral valve surgery in Northern New England","volume":"120","author":"Leavitt","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2016.10.015_bb0135","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/j.jacc.2014.02.536","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0140","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.jacc.2009.03.077","article-title":"Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort","volume":"54","author":"Feldman","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2016.10.015_bb0145","first-page":"E552","article-title":"Staged total percutaneous treatment of aortic valve pathology and mitral regurgitation: institutional experience","volume":"82","author":"Kische","year":"2013","journal-title":"Catheter Cardiovasc Interv"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000287031630237X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000287031630237X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:57:38Z","timestamp":1757570258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000287031630237X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":29,"alternative-id":["S000287031630237X"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2016.10.015","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of functional vs degenerative mitral regurgitation on clinical outcomes among patients undergoing transcatheter aortic valve implantation","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2016.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}