{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:25:02Z","timestamp":1784132702881,"version":"3.55.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T00:00:00Z","timestamp":1479686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.ahj.2016.10.020","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T05:30:56Z","timestamp":1478151056000},"page":"97-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Inadequacy of existing clinical prediction models for predicting mortality after transcatheter aortic valve implantation"],"prefix":"10.1016","volume":"184","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3410-9472","authenticated-orcid":false,"given":"Glen P.","family":"Martin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5351-9960","authenticated-orcid":false,"given":"Matthew","family":"Sperrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Ludman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"de Belder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris P.","family":"Gale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Toff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil E.","family":"Moat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7078-2760","authenticated-orcid":false,"given":"Uday","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Buchan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamas A.","family":"Mamas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2016.10.020_bb0005","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1093\/eurheartj\/ehi471","article-title":"Decision-making in elderly patients with severe aortic stenosis: Why are so many denied surgery?","volume":"26","author":"Iung","year":"2005","journal-title":"Eur Heart J"},{"issue":"17","key":"10.1016\/j.ahj.2016.10.020_bb0010","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","article-title":"Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery","volume":"363","author":"Leon","year":"2010","journal-title":"N Engl J Med"},{"issue":"23","key":"10.1016\/j.ahj.2016.10.020_bb0015","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus surgical aortic-valve replacement in high-risk patients","volume":"364","author":"Smith","year":"2011","journal-title":"N Engl J Med"},{"issue":"19","key":"10.1016\/j.ahj.2016.10.020_bb0020","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1093\/eurheartj\/ehs109","article-title":"Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"33","author":"Vahanian","year":"2012","journal-title":"Eur Heart J"},{"issue":"17","key":"10.1016\/j.ahj.2016.10.020_bb0025","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients","volume":"374","author":"Leon","year":"2016","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.ahj.2016.10.020_bb0030","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1093\/ejcts\/ezs043","article-title":"EuroSCORE II","volume":"41","author":"Nashef","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"issue":"9","key":"10.1016\/j.ahj.2016.10.020_bb0035","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0195-668X(02)00799-6","article-title":"The logistic EuroSCORE","volume":"24","author":"Roques","year":"2003","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.ahj.2016.10.020_bb0040","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/j.athoracsur.2009.05.056","article-title":"The Society of Thoracic Surgeons 2008 Cardiac Surgery Risk Models: Part 2\u2014Isolated Valve Surgery","volume":"88","author":"O'Brien","year":"2009","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.ahj.2016.10.020_bb0045","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.amjcard.2012.11.056","article-title":"Performance analysis of EuroSCORE II compared to the original logistic EuroSCORE and STS scores for predicting 30-day mortality after transcatheter aortic valve replacement","volume":"111","author":"Durand","year":"2013","journal-title":"Am J Cardiol"},{"issue":"2","key":"10.1016\/j.ahj.2016.10.020_bb0050","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ahj.2009.11.026","article-title":"Relationship between the logistic EuroSCORE and the Society of Thoracic Surgeons Predicted Risk of Mortality score in patients implanted with the CoreValve ReValving system\u2014a Bern-Rotterdam Study","volume":"159","author":"Piazza","year":"2010","journal-title":"Am Heart J"},{"issue":"6","key":"10.1016\/j.ahj.2016.10.020_bb0055","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.carrev.2011.04.005","article-title":"Comparison between Society of Thoracic Surgeons score and logistic EuroSCORE for predicting mortality in patients referred for transcatheter aortic valve implantation","volume":"12","author":"Ben-Dor","year":"2011","journal-title":"Cardiovasc Revasc Med"},{"issue":"11","key":"10.1016\/j.ahj.2016.10.020_bb0060","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1016\/j.amjcard.2014.03.014","article-title":"A simple risk tool (the OBSERVANT score) for prediction of 30-day mortality after transcatheter aortic valve replacement","volume":"113","author":"Capodanno","year":"2014","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.ahj.2016.10.020_bb0065","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/ejcts\/ezt114","article-title":"German Aortic Valve Score: a new scoring system for prediction of mortality related to aortic valve procedures in adults","volume":"43","author":"Kotting","year":"2013","journal-title":"Eur J Cardiothorac Surg"},{"issue":"13","key":"10.1016\/j.ahj.2016.10.020_bb0070","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1136\/heartjnl-2013-305314","article-title":"Predictive factors of early mortality after transcatheter aortic valve implantation: individual risk assessment using a simple score","volume":"100","author":"Iung","year":"2014","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.ahj.2016.10.020_bb0075","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1001\/jamacardio.2015.0326","article-title":"Development and Validation of a Risk Prediction Model for In-Hospital Mortality After Transcatheter Aortic Valve Replacement","volume":"1","author":"Edwards","year":"2016","journal-title":"JAMA Cardiol"},{"issue":"24","key":"10.1016\/j.ahj.2016.10.020_bb0080","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1136\/heartjnl-2012-302534","article-title":"The UK transcatheter aortic valve implantation registry; one of the suite of registries hosted by the National Institute for Cardiovascular Outcomes Research (NICOR)","volume":"98","author":"Ludman","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.ahj.2016.10.020_bb0085","series-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"issue":"1","key":"10.1016\/j.ahj.2016.10.020_bb0090","doi-asserted-by":"crossref","first-page":"b2393","DOI":"10.1136\/bmj.b2393","article-title":"Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls","volume":"338","author":"Sterne","year":"2009","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.ahj.2016.10.020_bb0095","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/biomet\/45.3-4.562","article-title":"Two further applications of a model for binary regression","volume":"45","author":"Cox","year":"1958","journal-title":"Biometrika"},{"issue":"1","key":"10.1016\/j.ahj.2016.10.020_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1175\/1520-0493(1950)078<0001:VOFEIT>2.0.CO;2","article-title":"Verification of Forecasts Expressed in Terms of Probability","volume":"78","author":"Brier","year":"1950","journal-title":"Mon Weather Rev"},{"issue":"5","key":"10.1016\/j.ahj.2016.10.020_bb0105","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1037\/h0031619","article-title":"Measuring nominal scale agreement among many raters","volume":"76","author":"Fleiss","year":"1971","journal-title":"Psychol Bull"},{"key":"10.1016\/j.ahj.2016.10.020_bb0110","series-title":"R Foundation for Statistical Computing","article-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team R","year":"2016"},{"issue":"3","key":"10.1016\/j.ahj.2016.10.020_bb0115","first-page":"1","article-title":"Mice: Multivariate Imputation by Chained Equations in R","volume":"45","author":"Van Buuren","year":"2011","journal-title":"J Stat Softw"},{"key":"10.1016\/j.ahj.2016.10.020_bb0120","series-title":"ggplot2: elegant graphics for data analysis","author":"Wickham","year":"2009"},{"key":"10.1016\/j.ahj.2016.10.020_bb0125","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1471-2105-12-77","article-title":"pROC: an open-source package for R and S+ to analyze and compare ROC curves","volume":"12","author":"Robin","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ahj.2016.10.020_bb0130","doi-asserted-by":"crossref","first-page":"b605","DOI":"10.1136\/bmj.b605","article-title":"Prognosis and prognostic research: validating a prognostic model","volume":"338","author":"Altman","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2016.10.020_bb0135","doi-asserted-by":"crossref","first-page":"i3140","DOI":"10.1136\/bmj.i3140","article-title":"External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges","volume":"353","author":"Riley","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2016.10.020_bb0140","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ijcard.2016.04.038","article-title":"Mortality prediction following transcatheter aortic valve replacement: A quantitative comparison of risk scores derived from populations treated with either surgical or percutaneous aortic valve replacement. The Israeli TAVR Registry Risk Model Accuracy A","volume":"215","author":"Halkin","year":"2016","journal-title":"Int J Cardiol"},{"issue":"8","key":"10.1016\/j.ahj.2016.10.020_bb0145","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0895-4356(01)00341-9","article-title":"Internal validation of predictive models","volume":"54","author":"Steyerberg","year":"2001","journal-title":"J Clin Epidemiol"},{"issue":"3","key":"10.1016\/j.ahj.2016.10.020_bb0150","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.amjcard.2015.04.047","article-title":"Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study)","volume":"116","author":"Mamas","year":"2015","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.ahj.2016.10.020_bb0155","doi-asserted-by":"crossref","first-page":"609","DOI":"10.4244\/EIJY14M08_03","article-title":"Impact of frailty on short and long term morbidity and mortality after transcatheter aortic valve implantation: risk assessment by Katz Index of activities of daily living","volume":"10","author":"Puls","year":"2014","journal-title":"EuroIntervention"},{"issue":"9","key":"10.1016\/j.ahj.2016.10.020_bb0160","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/eurheartj\/ehs304","article-title":"Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI)","volume":"34","author":"Schoenenberger","year":"2013","journal-title":"Eur Heart J"},{"issue":"8","key":"10.1016\/j.ahj.2016.10.020_bb0165","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00392-014-0692-4","article-title":"Development of a risk score for outcome after transcatheter aortic valve implantation","volume":"103","author":"Seiffert","year":"2014","journal-title":"Clin Res Cardiol"},{"issue":"25","key":"10.1016\/j.ahj.2016.10.020_bb0170","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1161\/CIRCULATIONAHA.113.007477","article-title":"Predictors of poor outcomes after transcatheter aortic valve replacement results from the PARTNER (Placement of Aortic Transcatheter Valve) trial","volume":"129","author":"Arnold","year":"2014","journal-title":"Circulation"},{"issue":"13","key":"10.1016\/j.ahj.2016.10.020_bb0175","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1161\/CIRCULATIONAHA.114.013947","article-title":"Transcatheter Aortic Valve Implantation in the UK: Temporal Trends, Predictors of Outcome and 6 Year Follow Up: A Report from the UK TAVI Registry 2007 to 2012","volume":"131","author":"Ludman","year":"2015","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.ahj.2016.10.020_bb0180","first-page":"977","article-title":"Transcatheter aortic valve implantation: Lessons from the learning curve of the first 270 high-risk patients","volume":"78","author":"Gurvitch","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"issue":"Suppl. 1","key":"10.1016\/j.ahj.2016.10.020_bb0185","first-page":"S124","article-title":"Transapical Aortic Valve Implantation: Analysis of Risk Factors and Learning Experience in 299 Patients","volume":"124","author":"Kempfert","year":"2011","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.ahj.2016.10.020_bb0190","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1093\/eurheartj\/ehq261","article-title":"Transcatheter aortic valve implantation: early results of the FRANCE (FRench Aortic National CoreValve and Edwards) registry","volume":"32","author":"Eltchaninoff","year":"2011","journal-title":"Eur Heart J"},{"issue":"8","key":"10.1016\/j.ahj.2016.10.020_bb0195","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1093\/eurheartj\/ehr491","article-title":"Transcatheter aortic valve implantation: 3-year outcomes of self-expanding CoreValve prosthesis","volume":"33","author":"Ussia","year":"2012","journal-title":"Eur Heart J"},{"issue":"3","key":"10.1016\/j.ahj.2016.10.020_bb0200","doi-asserted-by":"crossref","first-page":"307","DOI":"10.2307\/2987937","article-title":"Measurement in medicine: the analysis of method comparison studies","volume":"32","author":"Altman","year":"1983","journal-title":"Statistician"},{"issue":"16","key":"10.1016\/j.ahj.2016.10.020_bb0205","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1002\/sim.1844","article-title":"Validation and updating of predictive logistic regression models: a study on sample size and shrinkage","volume":"23","author":"Steyerberg","year":"2004","journal-title":"Stat Med"},{"key":"10.1016\/j.ahj.2016.10.020_bb0210","first-page":"ehv756","article-title":"TAVI or No TAVI: identifying patients unlikely to benefit from transcatheter aortic valve implantation","author":"Puri","year":"2016","journal-title":"Eur Heart J"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870316302447?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870316302447?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T05:57:56Z","timestamp":1757570276000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870316302447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":42,"alternative-id":["S0002870316302447"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2016.10.020","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inadequacy of existing clinical prediction models for predicting mortality after transcatheter aortic valve implantation","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2016.10.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}