{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:54:03Z","timestamp":1780048443480,"version":"3.53.1"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,6,21]],"date-time":"2018-06-21T00:00:00Z","timestamp":1529539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["120389"],"award-info":[{"award-number":["120389"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004828","name":"Grand Challenges Canada","doi-asserted-by":"publisher","award":["0069-04"],"award-info":[{"award-number":["0069-04"]}],"id":[{"id":"10.13039\/501100004828","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004828","name":"Grand Challenges Canada","doi-asserted-by":"publisher","award":["0070-04"],"award-info":[{"award-number":["0070-04"]}],"id":[{"id":"10.13039\/501100004828","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Department of Management of Noncommunicable Diseases, WHO"},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.ahj.2018.06.004","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T00:14:19Z","timestamp":1529626459000},"page":"57-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension: The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study"],"prefix":"10.1016","volume":"203","author":[{"given":"Jon-David Reid","family":"Schwalm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"McCready","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Lamelas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Musa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"Lopez-Jaramillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Yusoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"McKee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Anthony","family":"Camacho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Lopez-Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadhlina","family":"Majid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lehana","family":"Thabane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shofiqul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Yusuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2018.06.004_bb0005","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/S0140-6736(17)32130-X","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the global burden of disease study 2016","volume":"390","author":"Iburg","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2018.06.004_bb0010","series-title":"Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: A systematic analysis for the Global Burden of Disease Study 2016","author":"Doku","year":"2017"},{"key":"10.1016\/j.ahj.2018.06.004_bb0015","series-title":"Global Health Observatory (GHO) data: NCD mortality and morbidity","author":"World Health Organization","year":"2015"},{"key":"10.1016\/j.ahj.2018.06.004_bb0020","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","article-title":"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the Interheart study): case-control study","volume":"364","author":"Yusuf","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2018.06.004_bb0025","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1016\/j.jacc.2006.04.026","article-title":"AHA\/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update endorsed by the National Heart, Lung, and Blood Institute","volume":"47","author":"Smith","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0030","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1161\/CIRCOUTCOMES.111.963637","article-title":"Comparison of risk factor reduction and tolerability of a full-dose polypill (with potassium) versus low-dose polypill (polycap) in individuals at high risk of cardiovascular diseases: the Second Indian Polycap Study (TIPS-2) Investigators","volume":"5","author":"Yusuf","year":"2012","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.ahj.2018.06.004_bb0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0084238","article-title":"Patient and healthcare provider barriers to hypertension awareness, treatment and follow up: a systematic review and meta-analysis of qualitative and quantitative studies","volume":"9","author":"Khatib","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ahj.2018.06.004_bb0040","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12913-015-0916-y","article-title":"Understanding the modifiable health systems barriers to hypertension management in Malaysia: a multi-method health systems appraisal approach","volume":"15","author":"Risso-Gill","year":"2015","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.ahj.2018.06.004_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0122112","article-title":"Patients\u2019 knowledge, attitudes, behaviour and health care experiences on the prevention, detection, management and control of hypertension in colombia: a qualitative study","volume":"10","author":"Legido-Quigley","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ahj.2018.06.004_bb0050","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jama.2013.184182","article-title":"Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries","volume":"310","author":"Chow","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2018.06.004_bb0055","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00004872-200401000-00003","article-title":"Worldwide prevalence of hypertension: a systematic review","volume":"22","author":"Kearney","year":"2004","journal-title":"J Hypertens"},{"key":"10.1016\/j.ahj.2018.06.004_bb0060","series-title":"Global burden of disease and risk factors","author":"Lopez","year":"2006"},{"key":"10.1016\/j.ahj.2018.06.004_bb0065","series-title":"Selected leading causes of death","author":"Statistics Canada","year":"2005"},{"key":"10.1016\/j.ahj.2018.06.004_bb0070","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0140-6736(11)61215-4","article-title":"Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE study): a prospective epidemiological survey","volume":"378","author":"Yusuf","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2018.06.004_bb0075","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0140-6736(15)00469-9","article-title":"Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the pure study data","volume":"387","author":"Khatib","year":"2015","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.ahj.2018.06.004_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001490","article-title":"The influence of health systems on hypertension awareness, treatment, and control: a systematic literature review","volume":"10","author":"Maimaris","year":"2013","journal-title":"PLoS Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0085","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1093\/eurheartj\/ehs481","article-title":"Why are we failing to implement effective therapies in cardiovascular disease?","volume":"34","author":"Nieuwlaat","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2018.06.004_bb0090","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1016\/S2214-109X(17)30411-4","article-title":"Effectiveness of a lifestyle intervention led by female community health volunteers versus usual care in blood pressure reduction (COBIN): an open-label, cluster-randomised trial","volume":"6","author":"Neupane","year":"2018","journal-title":"Lancet Glob Health"},{"key":"10.1016\/j.ahj.2018.06.004_bb0095","doi-asserted-by":"crossref","first-page":"432","DOI":"10.2471\/BLT.06.032177","article-title":"Can non-physician health-care workers assess and manage cardiovascular risk in primary care?","volume":"85","author":"Abegunde","year":"2007","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ahj.2018.06.004_bb0100","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0968-8080(09)33446-1","article-title":"Community-based skilled birth attendants in bangladesh: attending deliveries at home","volume":"17","author":"Ahmed","year":"2009","journal-title":"Reprod Health Matters"},{"key":"10.1016\/j.ahj.2018.06.004_bb0105","first-page":"219","article-title":"Effect of mobile health interventions on the secondary prevention of cardiovascular disease: systematic review and meta-analysis","volume":"33","author":"Gandhi","year":"2017","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0110","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/HCO.0000000000000433","article-title":"Effective approaches to address the global cardiovascular disease burden","volume":"32","author":"Lamelas","year":"2017","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0115","series-title":"WHO CVD-risk management package for low- and medium-resource settings","author":"World Health Organization","year":"2002"},{"key":"10.1016\/j.ahj.2018.06.004_bb0120","series-title":"Task shifting to tackle health worker shortages","first-page":"1","author":"World Health Organization","year":"2007"},{"key":"10.1016\/j.ahj.2018.06.004_bb0125","first-page":"407","article-title":"Canadian Hypertension Education Program: the science supporting new 2011 CHEP recommendations with an emphasis on health advocacy and knowledge translation","volume":"27","author":"Campbell","year":"2011","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0130","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1016\/j.jacc.2010.09.001","article-title":"2010 ACCF\/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation\/American Heart Association task force on practice guidelines","volume":"56","author":"Greenland","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0135","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/HJH.0b013e3281fc975a","article-title":"2007 guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)","volume":"25","author":"Mancia","year":"2007","journal-title":"J Hypertens"},{"key":"10.1016\/j.ahj.2018.06.004_bb0140","doi-asserted-by":"crossref","first-page":"113","DOI":"10.18359\/rmed.1164","article-title":"Latin American consensus on hypertension in patients with type 2 diabetes and metabolic syndrome","volume":"21","author":"L\u00f3pez-Jaramillo","year":"2013","journal-title":"Rev Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0145","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1001\/jama.293.10.1223","article-title":"Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review","volume":"293","author":"Garg","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2018.06.004_bb0150","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1136\/bmj.38398.500764.8F","article-title":"Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success","volume":"330","author":"Kawamoto","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2018.06.004_bb0155","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1748-5908-8-137","article-title":"A multifaceted strategy using mobile technology to assist rural primary healthcare doctors and frontline health workers in cardiovascular disease risk management: protocol for the Smarthealth India cluster randomised controlled trial","volume":"8","author":"Praveen","year":"2013","journal-title":"Implement Sci"},{"key":"10.1016\/j.ahj.2018.06.004_bb0160","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00228-012-1419-y","article-title":"Nurse-led interventions to enhance adherence to chronic medication: systematic review and meta-analysis of randomised controlled trials","volume":"69","author":"Van Camp","year":"2013","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0165","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/1745-6215-15-143","article-title":"Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial","volume":"15","author":"Vedanthan","year":"2014","journal-title":"Trials"},{"key":"10.1016\/j.ahj.2018.06.004_bb0170","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":"Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2018.06.004_bb0175","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1056\/NEJMoa1600175","article-title":"Blood-pressure lowering in intermediate-risk persons without cardiovascular disease","volume":"374","author":"Lonn","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0180","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1056\/NEJMoa1600176","article-title":"Cholesterol lowering in intermediate-risk persons without cardiovascular disease","volume":"374","author":"Yusuf","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0185","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1056\/NEJMoa1600177","article-title":"Blood-pressure and cholesterol lowering in persons without cardiovascular disease","volume":"374","author":"Yusuf","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0190","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0140-6736(03)12948-0","volume":"361","author":"Sever","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2018.06.004_bb0195","series-title":"Clinical Epidemiology and Biostatistics, Health Research Methodology Program","article-title":"Barriers to the management of cardiovascular disease: a focus on availability and affordability of medications in 17 countries","author":"Khatib","year":"2014"},{"key":"10.1016\/j.ahj.2018.06.004_bb0200","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1097\/QAD.0b013e328339e20e","article-title":"Randomized controlled trial of trained patient-nominated treatment supporters providing partial directly observed antiretroviral therapy","volume":"24","author":"Nachega","year":"2010","journal-title":"AIDS"},{"issue":"15","key":"10.1016\/j.ahj.2018.06.004_bb0205","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1001\/jama.282.15.1458","article-title":"Why don't physicians follow clinical practice guidelines? A framework for imrovement","volume":"282","author":"Cabana","year":"1999","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.ahj.2018.06.004_bb0210","series-title":"WHO's Framework for Action","article-title":"WHO: everybody's business: strengthnening heath systems to improve health outcomes","author":"World Health Organization","year":"2007"},{"key":"10.1016\/j.ahj.2018.06.004_bb0215","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1161\/CIRCULATIONAHA.115.008721","article-title":"Resource effective strategies to prevent and treat cardiovascular disease","volume":"133","author":"Schwalm","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2018.06.004_bb0220","first-page":"18","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials","volume":"8","author":"Schulz","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.gheart.2017.11.002","article-title":"Development, testing, and implementation of a training curriculum for nonphysician health workers to reduce cardiovascular disease","author":"Khan","year":"2018","journal-title":"Glob Heart"},{"key":"10.1016\/j.ahj.2018.06.004_bb0230","series-title":"HOPE-4 technical paper on the mhealth tablet (temporary unpublished title)","author":"Schwalm","year":"2018"},{"key":"10.1016\/j.ahj.2018.06.004_bb0235","series-title":"Package of essential ncd interventions for primary health care: cancer, diabetes, heart disease and stroke, chronic respiratory disease","year":"2010"},{"key":"10.1016\/j.ahj.2018.06.004_bb0240","series-title":"The WHO stepwise approach to noncommunicable disease risk factor surveillance","author":"World Health Organization","year":"2017"},{"key":"10.1016\/j.ahj.2018.06.004_bb0245","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073529","article-title":"Framingham risk score for prediction of cardiovascular diseases: a population-based study from southern europe","volume":"8","author":"Artigao-Rodenas","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ahj.2018.06.004_bb0250","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-007324","article-title":"Validation of the Framingham general cardiovascular risk score in a multiethnic asian population: a retrospective cohort study","volume":"5","author":"Chia","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.ahj.2018.06.004_bb0255","series-title":"Framingham Heart Study: a project of National Heart, Lung, and Blood Institute and Boston University","article-title":"Cardiovascular disease (10-year risk)","author":"Framingham Heart Study","year":"2018"},{"key":"10.1016\/j.ahj.2018.06.004_bb0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ahj.2009.04.019","article-title":"The prospective urban rural epidemiology (pure) study: Examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries","volume":"158","author":"Teo","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2018.06.004_bb0265","doi-asserted-by":"crossref","first-page":"e411","DOI":"10.1016\/S2468-2667(17)30141-X","article-title":"Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the pure study data","volume":"2","author":"Marjan","year":"2017","journal-title":"Lancet Public Health"},{"key":"10.1016\/j.ahj.2018.06.004_bb0270","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.e5661","article-title":"CONSORT 2010 statement: extension to cluster randomised trials","volume":"345","author":"Campbell","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2018.06.004_bb0275","series-title":"Analysis of incomplete multivariate data","author":"Schafer","year":"1997"},{"key":"10.1016\/j.ahj.2018.06.004_bb0280","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1471-2288-9-37","article-title":"Comparison of bayesian and classical methods in the analysis of cluster randomized controlled trials with a binary outcome: the Community Hypertension Assessment Trial (CHAT)","volume":"9","author":"Ma","year":"2009","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.ahj.2018.06.004_bb0285","series-title":"Generalized estimating equations","author":"Hardin","year":"2003"},{"key":"10.1016\/j.ahj.2018.06.004_bb0290","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1056\/NEJMsa053935","article-title":"Explaining the decrease in U.S. Deaths from coronary disease, 1980-2000","volume":"356","author":"Ford","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2018.06.004_bb0295","series-title":"Generalized estimating equations","author":"Hardin","year":"2002"},{"key":"10.1016\/j.ahj.2018.06.004_bb0300","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1136\/bmj.326.7404.1419","article-title":"A strategy to reduce cardiovascular disease by more than 80%","volume":"326","author":"Wald","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2018.06.004_bb0305","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0140-6736(02)09358-3","article-title":"Two decades of progress in preventing vascular disease","volume":"360","author":"Yusuf","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2018.06.004_bb0310","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1136\/bmj.326.7404.1427","article-title":"Value of low dose combination treatment with blood pressure lowering drugs: Analysis of 354 randomised trials","volume":"326","author":"Law","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2018.06.004_bb0315","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/17441692.2011.574230","article-title":"Un resolution on the prevention and control of non-communicable diseases: AN opportunity for global action","volume":"6","author":"Mamudu","year":"2011","journal-title":"Glob Public Health"},{"key":"10.1016\/j.ahj.2018.06.004_bb0320","series-title":"2008-2013 action plan for the global strategy for the prevention and control of noncommunicable diseases","author":"World Health Organization","year":"2009"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870318301807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870318301807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:00:03Z","timestamp":1757570403000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870318301807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":64,"alternative-id":["S0002870318301807"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2018.06.004","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension: The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2018.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}