{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T08:12:58Z","timestamp":1785658378861,"version":"3.56.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1100377"],"award-info":[{"award-number":["APP1100377"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1105447"],"award-info":[{"award-number":["APP1105447"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1092642"],"award-info":[{"award-number":["APP1092642"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1052555"],"award-info":[{"award-number":["APP1052555"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["APP1136898"],"award-info":[{"award-number":["APP1136898"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["2018-2019"],"award-info":[{"award-number":["2018-2019"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["APP1080404"],"award-info":[{"award-number":["APP1080404"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["101884"],"award-info":[{"award-number":["101884"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["APP1136372"],"award-info":[{"award-number":["APP1136372"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["APP1125044"],"award-info":[{"award-number":["APP1125044"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1100377"],"award-info":[{"award-number":["APP1100377"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.ahj.2020.09.017","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T18:11:20Z","timestamp":1601662280000},"page":"56-67","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Ultra-low-dose quadruple combination blood pressure\u2013lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol"],"prefix":"10.1016","volume":"231","author":[{"given":"Clara K.","family":"Chow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily R.","family":"Atkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Billot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham S.","family":"Hillis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Neal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anushka","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Schlaich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Usherwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Webster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Rodgers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2020.09.017_bb0005","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1016\/S0140-6736(12)61766-8","article-title":"A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990\u20132010: a systematic analysis for the global burden of disease study 2010","volume":"380","author":"Lim","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0010","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0140-6736(03)14739-3","article-title":"Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials","volume":"362","author":"Turnbull","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0015","doi-asserted-by":"crossref","first-page":"b1665","DOI":"10.1136\/bmj.b1665","article-title":"Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies","volume":"338","author":"Law","year":"2009","journal-title":"BMJ (Clinical research ed)"},{"key":"10.1016\/j.ahj.2020.09.017_bb0020","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/S0140-6736(04)16451-9","article-title":"Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the value randomised trial","volume":"363","author":"Julius","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0025","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jama.2013.184182","article-title":"Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries","volume":"310","author":"Chow","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2020.09.017_bb0030","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0140-6736(09)60330-5","article-title":"Cardiovascular prevention guidelines in daily practice: a comparison of euroaspire i, ii, and iii surveys in eight european countries","volume":"373","author":"Kotseva","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0035","doi-asserted-by":"crossref","first-page":"304","DOI":"10.5694\/j.1326-5377.2009.tb02811.x","article-title":"Cardiovascular disease risk management for aboriginal and Torres Strait islander peoples in primary health care settings: findings from the Kanyini audit","volume":"191","author":"Peiris","year":"2009","journal-title":"Med J Aust"},{"key":"10.1016\/j.ahj.2020.09.017_bb0040","doi-asserted-by":"crossref","first-page":"324","DOI":"10.5694\/j.1326-5377.2009.tb02816.x","article-title":"Gaps in cardiovascular disease risk management in Australian general practice","volume":"191","author":"Webster","year":"2009","journal-title":"Med J Aust"},{"key":"10.1016\/j.ahj.2020.09.017_bb0045","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1097\/HJH.0b013e32835f7eef","article-title":"Global survey of current practice in management of hypertension as reported by societies affiliated with the International Society of Hypertension","volume":"31","author":"Chalmers","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.ahj.2020.09.017_bb0050","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.ahj.2011.05.010","article-title":"Combination therapy as initial treatment for newly diagnosed hypertension","volume":"162","author":"Byrd","year":"2011","journal-title":"Am Heart J"},{"key":"10.1016\/j.ahj.2020.09.017_bb0055","first-page":"ehy339","article-title":"2018 ESC\/ESH guidelines for the management of arterial hypertension","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2020.09.017_bb0060","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1136\/bmj.39553.670231.25","article-title":"Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories","volume":"336","author":"Vrijens","year":"2008","journal-title":"BMJ (Clinical research ed)"},{"key":"10.1016\/j.ahj.2020.09.017_bb0065","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1056\/NEJMra050100","article-title":"Adherence to medication","volume":"353","author":"Osterberg","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ahj.2020.09.017_bb0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1001\/archinte.167.2.141","article-title":"Outpatient hypertension treatment, treatment intensification, and control in Western Europe and the United States","volume":"167","author":"Wang","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.ahj.2020.09.017_bb0075","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1161\/HYPERTENSIONAHA.117.09202","article-title":"Efficacy and safety of quarter-dose blood pressure\u2013lowering agents","volume":"70","author":"Bennett","year":"2017","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0080","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1161\/01.HYP.0000254479.66645.a3","article-title":"Low-dose quadruple antihypertensive combination: more efficacious than individual agents\u2014a preliminary report","volume":"49","author":"Mahmud","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0085","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0140-6736(17)30260-X","article-title":"Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review","volume":"389","author":"Chow","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0090","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.amjmed.2008.09.038","article-title":"Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials","volume":"122","author":"Wald","year":"2009","journal-title":"Am J Med"},{"key":"10.1016\/j.ahj.2020.09.017_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041297","article-title":"Randomized polypill crossover trial in people aged 50 and over","volume":"7","author":"Wald","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ahj.2020.09.017_bb0100","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1136\/bmj.326.7404.1427","article-title":"Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials","volume":"326","author":"Law","year":"2003","journal-title":"BMJ (Clinical Research Ed)"},{"key":"10.1016\/j.ahj.2020.09.017_bb0105","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1016\/S0140-6736(09)61913-9","article-title":"Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial","volume":"374","author":"Ma","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0110","series-title":"Guideline for the diagnosis and management of hypertension in adults","author":"National Heart Foundation Australia","year":"2016"},{"key":"10.1016\/j.ahj.2020.09.017_bb0115","article-title":"The clinical management of primary hypertension in adults","volume":"127","author":"National Institute for Health and Clinical Excellence","year":"2011","journal-title":"Clinical guideline"},{"key":"10.1016\/j.ahj.2020.09.017_bb0120","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1161\/HYPERTENSIONAHA.113.02252","article-title":"Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action in Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial","volume":"63","author":"Chalmers","year":"2014","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0125","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0140-6736(01)06178-5","article-title":"Randomised trial of a perindopril-based blood-pressure\u2013lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack","volume":"358","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0130","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1001\/jamainternmed.2019.7454","article-title":"Comparison of cardiovascular and safety outcomes of chlorthalidone vs hydrochlorothiazide to treat hypertension","volume":"180","author":"Hripcsak","year":"2020","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.ahj.2020.09.017_bb0135","unstructured":"Williams B, Mancia G. 2018 European Society of Cardiology (ESC) and European Society of Hypertension (ESH) joint guidelines for the management of arterial hypertension. J Hypertens. 2018;in press."},{"issue":"6","key":"10.1016\/j.ahj.2020.09.017_bb0140","first-page":"e13","article-title":"2017 ACC\/AHA\/AAPA\/ABC\/ACPM\/AGS\/APHA\/ASH\/ASPC\/NMA\/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults","volume":"71","author":"Whelton","year":"2018","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0145","series-title":"Guide to management of hypertension 2008","author":"National Heart Foundation Australia (National Blood Pressure and Vascular Disease Advisory Committee)","year":"2010"},{"key":"10.1016\/j.ahj.2020.09.017_bb0150","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1093\/eurheartj\/eht151","article-title":"2013 ESH\/ESC guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)","volume":"34","author":"Mancia","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.ahj.2020.09.017_bb0155","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/jama.2013.284427","article-title":"2014 Evidence-based guideline for the management of high blood pressure in adults","volume":"311","author":"James","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2020.09.017_bb0160","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/HJH.0b013e32834de621","article-title":"Stowasser M, Mangoni Aa, Cowley D, Brown Ma, Ruta L-A, Wilson A. Ambulatory blood pressure monitoring in Australia: 2011 consensus position statement","volume":"30","author":"Head","year":"2012","journal-title":"J Hypertens"},{"key":"10.1016\/j.ahj.2020.09.017_bb0165","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1161\/HYPERTENSIONAHA.113.02148","article-title":"Ambulatory blood pressure measurement: what is the international consensus?","volume":"62","author":"O'Brien","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0170","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s12325-014-0107-y","article-title":"Efficacy and tolerability of fixed-dose combination of perindopril\/indapamide in type 2 diabetes mellitus: Picasso trial","volume":"31","author":"Farsang","year":"2014","journal-title":"Adv Ther"},{"key":"10.1016\/j.ahj.2020.09.017_bb0175","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1016\/j.clinthera.2012.07.001","volume":"34","author":"Bobrie","year":"2012","journal-title":"Clin Ther"},{"key":"10.1016\/j.ahj.2020.09.017_bb0180","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/S0140-6736(17)32366-8","article-title":"Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"390","author":"Gakidou","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0185","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1001\/jama.2018.5119","article-title":"for the For the Institute for Health M, Evaluation. Global deaths attributable to high systolic blood pressure, 1990-2016","volume":"319","author":"Marczak","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2020.09.017_bb0190","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1161\/HYPERTENSIONAHA.108.123455","article-title":"A simplified approach to the treatment of uncomplicated hypertension: a cluster randomized, controlled trial","volume":"53","author":"Feldman","year":"2009","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0195","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/S0140-6736(98)07614-4","article-title":"Optimisation of antihypertensive treatment by crossover rotation of four major classes","volume":"353","author":"Dickerson","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ahj.2020.09.017_bb0200","doi-asserted-by":"crossref","first-page":"b1492","DOI":"10.1136\/bmj.b1492","article-title":"Long term monitoring in patients receiving treatment to lower blood pressure: analysis of data from placebo controlled randomised controlled trial","volume":"338","author":"Keenan","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.ahj.2020.09.017_bb0205","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1161\/HYPERTENSIONAHA.109.139816","article-title":"Compliance, safety, and effectiveness of fixed-dose combinations of antihypertensive agents: a meta-analysis","volume":"55","author":"Gupta","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.ahj.2020.09.017_bb0210","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/jch.12040","article-title":"The efficacy and safety of triple vs dual combination of angiotensin II receptor blocker and calcium channel blocker and diuretic: a systematic review and meta-analysis","volume":"15","author":"Kizilirmak","year":"2013","journal-title":"J Clin Hypertens"},{"key":"10.1016\/j.ahj.2020.09.017_bb0215","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s12325-012-0019-7","article-title":"Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials","volume":"29","author":"de la Sierra","year":"2012","journal-title":"Adv Ther"},{"key":"10.1016\/j.ahj.2020.09.017_bb0220","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1001\/jama.2018.10359","article-title":"Fixed low-dose triple combination antihypertensive medication vs usual care for blood pressure control in patients with mild to moderate hypertension in Sri Lanka: a randomized clinical trial","volume":"320","author":"Webster","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2020.09.017_bb0225","doi-asserted-by":"crossref","first-page":"e1359","DOI":"10.1016\/S2214-109X(19)30343-2","article-title":"Fixed-combination, low-dose, triple-pill antihypertensive medication versus usual care in patients with mild-to-moderate hypertension in Sri Lanka: a within-trial and modelled economic evaluation of the triumph trial","volume":"7","author":"Lung","year":"2019","journal-title":"Lancet Glob Health"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870320302738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870320302738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:05:27Z","timestamp":1757570727000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870320302738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":45,"alternative-id":["S0002870320302738"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2020.09.017","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultra-low-dose quadruple combination blood pressure\u2013lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2020.09.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}