{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T03:17:39Z","timestamp":1794021459054,"version":"4.8.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007497","name":"Biosense Webster","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 HL069749"],"award-info":[{"award-number":["T32 HL069749"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009938","name":"Knud H\u00f8jgaards Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009938","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.ahj.2020.10.053","type":"journal-article","created":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T02:43:55Z","timestamp":1603334635000},"page":"45-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions"],"prefix":"10.1016","volume":"231","author":[{"given":"Daniel J.","family":"Friedman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasper","family":"Emerek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kisslo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"S\u00f8gaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett D.","family":"Atwater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahj.2020.10.053_bb0005","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1161\/CIRCULATIONAHA.110.960898","article-title":"Effectiveness of cardiac resynchronization therapy by QRS morphology in the multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy (MADIT-CRT)","volume":"123","author":"Zareba","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2020.10.053_bb0010","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ahj.2012.01.025","article-title":"Simple regional strain pattern analysis to predict response to cardiac resynchronization therapy: rationale, initial results, and advantages","volume":"163","author":"Risum","year":"2012","journal-title":"Am Heart J Apr"},{"key":"10.1016\/j.ahj.2020.10.053_bb0015","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.jacc.2015.06.020","article-title":"Identification of typical left bundle branch block contraction by strain echocardiography is additive to electrocardiography in prediction of long-term outcome after cardiac resynchronization therapy","volume":"66","author":"Risum","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2020.10.053_bb0020","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/ejhf.172","article-title":"A prediction model for sudden cardiac death in patients with heart failure and preserved ejection fraction","volume":"16","author":"Adabag","year":"2014","journal-title":"Eur J Heart Fail Nov"},{"key":"10.1016\/j.ahj.2020.10.053_bb0025","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.amjcard.2005.08.031","article-title":"Comparison of six-month outcomes and hospitalization rates in heart failure patients with and without preserved left ventricular ejection fraction and with and without intraventricular conduction defect","volume":"97","author":"Danciu","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ahj.2020.10.053_bb0030","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.amjcard.2010.11.010","article-title":"Defining left bundle branch block in the era of cardiac resynchronization therapy","volume":"107","author":"Strauss","year":"2011","journal-title":"Am J Cardiol"},{"issue":"2","key":"10.1016\/j.ahj.2020.10.053_bb0035","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.hrthm.2018.08.028","article-title":"Vectorcardiographic QRS area is associated with long-term outcome after cardiac resynchronization therapy","volume":"16","author":"Emerek","year":"2018","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.ahj.2020.10.053_bb0040","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1111\/jce.14192","article-title":"Non-invasively quantified changes in left ventricular activation predict outcomes in patients undergoing cardiac resynchronization therapy","volume":"30","author":"Friedman","year":"2019","journal-title":"J Cardiovasc Electrophysiol Nov"},{"key":"10.1016\/j.ahj.2020.10.053_bb0045","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12947-019-0160-4","article-title":"The association of a classical left bundle branch block contraction pattern by vendor-independent strain echocardiography and outcome after cardiac resynchronization therapy","volume":"17","author":"Emerek","year":"2019","journal-title":"Cardiovasc Ultrasound"},{"key":"10.1016\/j.ahj.2020.10.053_bb0050","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.jelectrocard.2015.05.005","article-title":"Immediate mechanical effects of acute left bundle branch block by speckle tracked strain","volume":"48","author":"Klein","year":"2015","journal-title":"J Electrocardiol Jul-Aug"},{"key":"10.1016\/j.ahj.2020.10.053_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2008.11.029","article-title":"Echocardiographic assessment of valve stenosis: EAE\/ASE recommendations for clinical practice","volume":"22","author":"Baumgartner","year":"2009","journal-title":"J Am Soc Echocardiogr Jan"},{"key":"10.1016\/j.ahj.2020.10.053_bb0060","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of E. European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr May"},{"key":"10.1016\/j.ahj.2020.10.053_bb0065","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/clc.20932","article-title":"Usefulness of tissue Doppler imaging\u2013myocardial performance index in the evaluation of diastolic dysfunction and heart failure with preserved ejection fraction","volume":"34","author":"Kim","year":"2011","journal-title":"Clin Cardiol Aug"},{"key":"10.1016\/j.ahj.2020.10.053_bb0070","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jchf.2016.02.013","article-title":"QRS duration is a predictor of adverse outcomes in heart failure with preserved ejection fraction","volume":"4","author":"Joseph","year":"2016","journal-title":"JACC Heart Fail Jun"},{"key":"10.1016\/j.ahj.2020.10.053_bb0075","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1002\/ejhf.547","article-title":"Clinical outcomes according to QRS duration and morphology in the irbesartan in patients with heart failure and preserved systolic function (I-PRESERVE) trial","volume":"18","author":"Cannon","year":"2016","journal-title":"Eur J Heart Fail Aug"},{"key":"10.1016\/j.ahj.2020.10.053_bb0080","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jchf.2018.12.006","article-title":"Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction","volume":"7","author":"Shen","year":"2019","journal-title":"JACC Heart Fail May"},{"key":"10.1016\/j.ahj.2020.10.053_bb0085","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.amjcard.2010.09.044","article-title":"Usefulness of the myocardial performance index determined by tissue Doppler imaging m-mode for predicting mortality in the general population","volume":"107","author":"Biering-Sorensen","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ahj.2020.10.053_bb0090","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.cardfail.2016.01.005","article-title":"Myocardial performance index determined by tissue doppler imaging in patients with systolic heart failure predicts poor long-term prognosis: an observational cohort study","volume":"22","author":"Olson","year":"2016","journal-title":"J Card Fail Aug"},{"key":"10.1016\/j.ahj.2020.10.053_bb0095","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.echo.2008.11.027","article-title":"Effects of cardiac resynchronization therapy on the Doppler Tei index","volume":"22","author":"Yuasa","year":"2009","journal-title":"J Am Soc Echocardiogr Mar"},{"key":"10.1016\/j.ahj.2020.10.053_bb0100","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.jacc.2012.10.053","article-title":"Resolution of left bundle branch block\u2013induced cardiomyopathy by cardiac resynchronization therapy","volume":"61","author":"Vaillant","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ahj.2020.10.053_bb0105","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/eurjhf\/hfq068","article-title":"Cardiac resynchronization therapy for the causal treatment of heart failure with preserved ejection fraction: insight from a pressure-volume loop analysis","volume":"12","author":"Penicka","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.ahj.2020.10.053_bb0110","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.jelectrocard.2018.07.004","article-title":"The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block","volume":"51","author":"Friedman","year":"2018","journal-title":"J Electrocardiol"}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870320303380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870320303380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T09:57:44Z","timestamp":1762077464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870320303380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":22,"alternative-id":["S0002870320303380"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2020.10.053","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2020.10.053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}