{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:37:59Z","timestamp":1777448279885,"version":"3.51.4"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","award":["5R01CA20458504"],"award-info":[{"award-number":["5R01CA20458504"]}],"id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000038","name":"U.S. Food and Drug Administration","doi-asserted-by":"publisher","award":["5U01FD005978-04"],"award-info":[{"award-number":["5U01FD005978-04"]}],"id":[{"id":"10.13039\/100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","award":["AD-2018C1-11238"],"award-info":[{"award-number":["AD-2018C1-11238"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23 HL145017"],"award-info":[{"award-number":["K23 HL145017"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["18SFRN34120036"],"award-info":[{"award-number":["18SFRN34120036"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["20SFRN35360189"],"award-info":[{"award-number":["20SFRN35360189"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.ahj.2022.01.013","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T15:34:31Z","timestamp":1643384071000},"page":"68-75","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["The ENHANCE-AF clinical trial to evaluate an atrial fibrillation shared decision-making pathway: Rationale and study design"],"prefix":"10.1016","volume":"247","author":[{"given":"Tina","family":"Baykaner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Pundi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-0522","authenticated-orcid":false,"given":"Bryant","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"DeSutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karma","family":"Lhamo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gotzone","family":"Garay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio C.","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel P.","family":"Morin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7863-3591","authenticated-orcid":false,"given":"Samuel F.","family":"Sears","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7835-6045","authenticated-orcid":false,"given":"Mina K.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-7190","authenticated-orcid":false,"given":"Michael K.","family":"Paasche-Orlow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3231-6918","authenticated-orcid":false,"given":"Lee M.","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5349-0136","authenticated-orcid":false,"given":"Thomas Jared","family":"Bunch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mellanie True","family":"Hills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth W.","family":"Mahaffey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1805-1271","authenticated-orcid":false,"given":"Randall S.","family":"Stafford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9989","key":"10.1016\/j.ahj.2022.01.013_bib0001","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0140-6736(14)61774-8","article-title":"50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study","volume":"386","author":"Schnabel","year":"2015","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.ahj.2022.01.013_bib0002","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0735-1097(00)01107-4","article-title":"Epidemiology and natural history of atrial fibrillation: clinical implications","volume":"37","author":"Chugh","year":"2001","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ahj.2022.01.013_bib0003","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/cpt.1024","article-title":"Underuse of vitamin K antagonist and direct oral anticoagulants for stroke prevention in patients with atrial fibrillation: a contemporary review","volume":"104","author":"Hsu","year":"2018","journal-title":"Clin. Pharmacol. Ther."},{"issue":"8","key":"10.1016\/j.ahj.2022.01.013_bib0004","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.amjcard.2011.06.017","article-title":"Practice-level variation in warfarin use among outpatients with atrial fibrillation (from the NCDR PINNACLE program)","volume":"108","author":"Chan","year":"2011","journal-title":"Am. J. Cardiol."},{"issue":"6","key":"10.1016\/j.ahj.2022.01.013_bib0005","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1161\/CIRCULATIONAHA.113.004498","article-title":"Shared decision making in atrial fibrillation: where we are and where we should be going","volume":"129","author":"Seaburg","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.ahj.2022.01.013_bib0006","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1378\/chest.09-1584","article-title":"Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach","volume":"137","author":"Lip","year":"2010","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.ahj.2022.01.013_bib0007","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jacc.2019.01.011","volume":"74","author":"January","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.ahj.2022.01.013_bib0008","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1503\/cmaj.060837","article-title":"Influence of decision aids on patient preferences for anticoagulant therapy: a randomized trial","volume":"176","author":"Holbrook","year":"2007","journal-title":"CMAJ"},{"issue":"5","key":"10.1016\/j.ahj.2022.01.013_bib0009","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1503\/cmaj.050091","article-title":"Impact of a patient decision aid on care among patients with nonvalvular atrial fibrillation: a cluster randomized trial","volume":"173","author":"McAlister","year":"2005","journal-title":"CMAJ"},{"issue":"3","key":"10.1016\/j.ahj.2022.01.013_bib0010","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1136\/qshc.2006.018481","article-title":"A patient decision aid to support shared decision-making on anti-thrombotic treatment of patients with atrial fibrillation: randomised controlled trial","volume":"16","author":"Thomson","year":"2007","journal-title":"Qual. Saf. Health Care"},{"issue":"8","key":"10.1016\/j.ahj.2022.01.013_bib0011","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1001\/jama.282.8.737","article-title":"A patient decision aid regarding antithrombotic therapy for stroke prevention in atrial fibrillation: a randomized controlled trial","volume":"282","author":"Man-Son-Hing","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.ahj.2022.01.013_bib0012","series-title":"Health Literacy and Numeracy: Workshop Summary","article-title":"Board on Population Health and Public Health Practice & Roundtable on Health Literacy","year":"2014"},{"key":"10.1016\/j.ahj.2022.01.013_bib0013","doi-asserted-by":"crossref","first-page":"52","DOI":"10.15420\/ecr.2017:2:2","article-title":"Health literacy and atrial fibrillation: relevance and future directions for patient-centred care","volume":"12","author":"Aronis","year":"2017","journal-title":"Eur Cardiol Rev"},{"key":"10.1016\/j.ahj.2022.01.013_bib0014","article-title":"Health Literacy of America's adults: results from the 2003 National assessment of adult literacy","author":"White","year":"2007","journal-title":"PsycEXTRA Dataset"},{"key":"10.1016\/j.ahj.2022.01.013_bib0015","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1177\/0272989X9501500105","article-title":"Validation of a decisional conflict scale","volume":"15","author":"O'Connor","year":"1995","journal-title":"Med. Decis. Making"},{"issue":"4","key":"10.1016\/j.ahj.2022.01.013_bib0016","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1177\/0272989X03256005","article-title":"Validation of a decision regret scale","volume":"23","author":"Brehaut","year":"2003","journal-title":"Med. Decis. Making"},{"issue":"6","key":"10.1016\/j.ahj.2022.01.013_bib0017","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.120.009389","article-title":"Blood thinners for atrial fibrillation stroke prevention","volume":"14","author":"Pundi","year":"2021","journal-title":"Circ. Arrhythm. Electrophysiol."},{"key":"10.1016\/j.ahj.2022.01.013_bib0018","doi-asserted-by":"crossref","DOI":"10.1186\/s13063-017-2178-y","article-title":"Shared decision making for stroke prevention in atrial fibrillation: study protocol for a randomized controlled trial","volume":"18","author":"Kunneman","year":"2017","journal-title":"Trials"},{"key":"10.1016\/j.ahj.2022.01.013_bib0019","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/10485250500473099","article-title":"On power and sample size determinations for the Wilcoxon\u2013Mann\u2013Whitney test","volume":"18","author":"Shieh","year":"2006","journal-title":"J. Nonparametr. Stat."},{"key":"10.1016\/j.ahj.2022.01.013_bib0020","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1080\/10543406.2020.1730866","article-title":"Precise and accurate power of the rank-sum test for a continuous outcome","volume":"30","author":"Mollan","year":"2020","journal-title":"J Biopharm Stat"},{"issue":"9","key":"10.1016\/j.ahj.2022.01.013_bib0021","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1001\/jamainternmed.2020.2908","article-title":"Assessment of shared decision-making for stroke prevention in patients with atrial fibrillation: a randomized clinical trial","volume":"180","author":"Kunneman","year":"2020","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.ahj.2022.01.013_bib0022","article-title":"Literacy and health outcomes, summary, evidence report","volume":"87","author":"Berkman","year":"2004","journal-title":"Technol Assess"},{"key":"10.1016\/j.ahj.2022.01.013_bib0023","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000000579","article-title":"Health literacy and cardiovascular disease: fundamental relevance to primary and secondary prevention: a scientific statement from the American Heart Association","volume":"138","author":"Magnani","year":"2018","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.ahj.2022.01.013_bib0024","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1093\/her\/cym051","article-title":"Will patients agree to have their literacy skills assessed in clinical practice?","volume":"23","author":"Ryan","year":"2008","journal-title":"Health Educ. Res."},{"issue":"14","key":"10.1016\/j.ahj.2022.01.013_bib0025","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1001\/archinte.167.14.1503","article-title":"Health literacy and mortality among elderly persons","volume":"167","author":"Baker","year":"2007","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.ahj.2022.01.013_bib0026","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.pec.2008.07.018","article-title":"Barriers and facilitators to implementing shared decision-making in clinical practice: update of a systematic review of health professionals\u2019 perceptions","volume":"73","author":"L\u00e9gar\u00e9","year":"2008","journal-title":"Patient Educ. Couns."}],"container-title":["American Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870322000138?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002870322000138?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:37:31Z","timestamp":1777379851000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002870322000138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":26,"alternative-id":["S0002870322000138"],"URL":"https:\/\/doi.org\/10.1016\/j.ahj.2022.01.013","relation":{},"ISSN":["0002-8703"],"issn-type":[{"value":"0002-8703","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The ENHANCE-AF clinical trial to evaluate an atrial fibrillation shared decision-making pathway: Rationale and study design","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahj.2022.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}