{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T18:08:01Z","timestamp":1769105281518,"version":"3.49.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007217","name":"Health Services Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007217","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"US Department of Veterans Affairs","doi-asserted-by":"publisher","award":["LIP 18-SN-1"],"award-info":[{"award-number":["LIP 18-SN-1"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.ahjo.2022.100183","type":"journal-article","created":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T20:58:16Z","timestamp":1658523496000},"page":"100183","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Clinical predictors of improvement in left ventricular ejection fraction in U.S. veterans with heart failure"],"prefix":"10.1016","volume":"19","author":[{"given":"Shriram","family":"Nallamshetty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois","family":"Haddad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Heidenreich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahjo.2022.100183_bb0005","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/HHF.0b013e318291329a","article-title":"Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association","volume":"6","author":"Heidenreich","year":"2013","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0010","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1161\/CIRCHEARTFAILURE.111.966366","article-title":"Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction","volume":"5","author":"Dunlay","year":"2012","journal-title":"Circ Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0015","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1161\/CIRCULATIONAHA.113.006855","article-title":"Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes","volume":"129","author":"Basuray","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.ahjo.2022.100183_bb0020","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1159\/000447287","article-title":"Heart failure with recovered ejection fraction in a cohort of elderly patients with chronic heart failure","volume":"135","author":"Trull\u00e0s","year":"2016","journal-title":"Cardiology"},{"key":"10.1016\/j.ahjo.2022.100183_bb0025","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.jacc.2020.05.075","article-title":"Heart failure with recovered left ventricular ejection fraction: JACC scientific expert panel","volume":"76","author":"Wilcox","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"3","key":"10.1016\/j.ahjo.2022.100183_bb0030","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/ejhf.2115","volume":"23","author":"Bozkurt","year":"2021","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0035","article-title":"AHA\/ACC\/HFSA guideline for the Management of Heart Failure: a report of the american College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"2022","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.ahjo.2022.100183_bb0040","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.cardfail.2011.03.005","article-title":"Heart failure with recovered ejection fraction: a distinct clinical entity","volume":"17","author":"Punnoose","year":"2011","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0045","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1001\/jamacardio.2016.1325","article-title":"Characteristics and outcomes of adult outpatients with heart failure and improved or recovered ejection fraction","volume":"1","author":"Kalogeropoulos","year":"2016","journal-title":"JAMA Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0050","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003123","article-title":"Heart failure with improved ejection fraction: clinical characteristics, correlates of recovery, and survival: results from the valsartan heart failure trial","volume":"9","author":"Florea","year":"2016","journal-title":"Circ Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0055","doi-asserted-by":"crossref","first-page":"353","DOI":"10.5603\/CJ.a2017.0103","article-title":"Heart failure with recovered ejection fraction: clinical characteristics, determinants and prognosis. CARDIOCHUS-CHOP registry","volume":"25","author":"Agra Bermejo","year":"2018","journal-title":"Cardiol. J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0060","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cardfail.2017.09.005","article-title":"Heart failure with recovered ejection fraction in african americans: results from the african-american heart failure trial","volume":"24","author":"Chang","year":"2018","journal-title":"J. Card. Fail."},{"issue":"49\u201356","key":"10.1016\/j.ahjo.2022.100183_bb0065","article-title":"Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF","volume":"163","author":"Wilcox","year":"2012","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0070","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ahj.2007.08.010","article-title":"Recovery of normal ventricular function in patients with dilated cardiomyopathy: predictors of an increasingly prevalent clinical event","volume":"155","author":"Binkley","year":"2008","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0075","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.cardfail.2003.10.002","article-title":"Chronic left ventricular failure in the community: prevalence, prognosis, and predictors of the complete clinical recovery with return of cardiac size and function to normal in patients undergoing optimal therapy","volume":"10","author":"Cioffi","year":"2004","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0080","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1002\/ejhf.824","article-title":"Recovered heart failure with reduced ejection fraction and outcomes: a prospective study","volume":"19","author":"Lupon","year":"2017","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0085","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jchf.2018.11.019","article-title":"Prevalence and prognostic implications of longitudinal ejection fraction change in heart failure","volume":"7","author":"Savarese","year":"2019","journal-title":"JACC Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0090","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011077","article-title":"Characteristics, outcomes, and treatment of heart failure with improved ejection fraction","volume":"8","author":"Park","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ahjo.2022.100183_bb0095","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12872-017-0580-8","article-title":"Unlocking echocardiogram measurements for heart disease research through natural language processing","volume":"17","author":"Patterson","year":"2017","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.ahjo.2022.100183_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11897-019-00451-0","article-title":"Heart failure with mid-range ejection fraction","volume":"17","author":"Srivastava","year":"2020","journal-title":"Curr. Heart Fail. Rep."},{"key":"10.1016\/j.ahjo.2022.100183_bb0105","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ahj.2011.10.001","article-title":"Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF","volume":"163","author":"Wilcox","year":"2012","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0110","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.010881","article-title":"Clinical features and outcomes of patients with malignancy and takotsubo syndrome: observations from the international takotsubo registry","volume":"8","author":"Cammann","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.ahjo.2022.100183_bb0115","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0140-6736(18)32484-X","article-title":"Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial","volume":"393","author":"Halliday","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.ahjo.2022.100183_bb0120","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0002-8703(03)00248-5","article-title":"Reliability of reporting left ventricular systolic function by echocardiography: a systematic review of 3 methods","volume":"146","author":"McGowan","year":"2003","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0125","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00392-018-1363-7","article-title":"Test-retest reliability of new and conventional echocardiographic parameters of left ventricular systolic function","volume":"108","author":"Baron","year":"2019","journal-title":"Clin. Res. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0130","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s10741-017-9624-5","article-title":"Left ventricular ejection fraction as therapeutic target: is it the ideal marker?","volume":"22","author":"Katsi","year":"2017","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.ahjo.2022.100183_bb0135","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1067\/mhj.2001.115584","article-title":"Comparative effects of carvedilol and metoprolol on left ventricular ejection fraction in heart failure: results of a meta-analysis","volume":"141","author":"Packer","year":"2001","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0140","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S1388-9842(03)00105-3","volume":"5","author":"Waagstein","year":"2003","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0145","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1472-8206.2012.01029.x","article-title":"Beneficial effects of beta-blockers on left ventricular function and cellular energy reserve in patients with heart failure","volume":"27","author":"Spoladore","year":"2013","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0150","doi-asserted-by":"crossref","first-page":"271","DOI":"10.5152\/akd.2014.5337","article-title":"Carvedilol and nebivolol improve left ventricular systolic functions in patients with non-ischemic heart failure","volume":"15","author":"Karabacak","year":"2015","journal-title":"Anatol. J. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0155","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.recesp.2017.11.021","article-title":"Prognostic impact and predictors of ejection fraction recovery in patients with alcoholic cardiomyopathy","volume":"71","author":"Amor-Salamanca","year":"2018","journal-title":"Rev. Esp. Cardiol. (Engl. Ed.)"},{"key":"10.1016\/j.ahjo.2022.100183_bb0160","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0735-1097(97)00012-0","article-title":"Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand heart failure research collaborative group","volume":"29","author":"Doughty","year":"1997","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0165","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ejheart.2006.05.002","article-title":"A systematic review: effect of angiotensin converting enzyme inhibition on left ventricular volumes and ejection fraction in patients with a myocardial infarction and in patients with left ventricular dysfunction","volume":"9","author":"Abdulla","year":"2007","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ahjo.2022.100183_bb0170","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/S0735-1097(03)01042-8","article-title":"Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias","volume":"42","author":"Higgins","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0175","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa013168","article-title":"Cardiac resynchronization in chronic heart failure","volume":"346","author":"Abraham","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ahjo.2022.100183_bb0180","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1093\/eurheartj\/eht160","article-title":"Long-term impact of cardiac resynchronization therapy in mild heart failure: 5-year results from the REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study","volume":"34","author":"Linde","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0185","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.hlc.2015.10.014","article-title":"Effect of cardiac resynchronisation therapy on electrical remodelling","volume":"25","author":"Aslani","year":"2016","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.ahjo.2022.100183_bb0190","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/HCO.0000000000000566","article-title":"Left ventricular function recovery after revascularization: comparative effects of percutaneous coronary intervention and coronary artery bypass grafting","volume":"33","author":"Ngu","year":"2018","journal-title":"Curr. Opin. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0195","first-page":"273","article-title":"Recovery of left ventricular function after percutaneous coronary intervention compared to coronary artery bypass grafting in patients with multi-vessel coronary disease and left ventricular dysfunction","volume":"75","author":"Yee","year":"2016","journal-title":"Hawaii J. Med. Public Health"},{"key":"10.1016\/j.ahjo.2022.100183_bb0200","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/S0002-9149(03)00389-8","article-title":"Individual prediction of functional recovery after coronary revascularization in patients with ischemic cardiomyopathy: the scar-to-biphasic model","volume":"91","author":"Rizzello","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0205","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1536\/ihj.16-087","article-title":"Determinants of left ventricular systolic function improvement following coronary artery revascularization in heart failure patients with reduced ejection fraction (HFrEF)","volume":"57","author":"Adachi","year":"2016","journal-title":"Int. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0210","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S1010-7940(03)00575-X","article-title":"Aortic valve replacement in severe aortic stenosis with left ventricular dysfunction: determinants of cardiac mortality and ventricular function recovery","volume":"24","author":"Tarantini","year":"2003","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.ahjo.2022.100183_bb0215","first-page":"132","article-title":"Transcatheter aortic valve implantation in patients with LV dysfunction: impact on mortality and predictors of LV function recovery","volume":"26","author":"Elhmidi","year":"2014","journal-title":"J. Invasive Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0220","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12872-017-0523-4","article-title":"Clinical outcomes of conventional surgery versus MitraClip(R) therapy for moderate to severe symptomatic mitral valve regurgitation in the elderly population: an institutional experience","volume":"17","author":"Alozie","year":"2017","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.ahjo.2022.100183_bb0225","first-page":"36","article-title":"Effects of sinus rhythm maintenance on left heart function after electrical cardioversion of atrial fibrillation: implications for tachycardia-induced cardiomyopathy","volume":"31","author":"Zimmermann","year":"2015","journal-title":"Can. J. Cardiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0230","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1046\/j.1365-2281.2000.00249.x","article-title":"The relation between ejection fraction and mitral annulus motion before and after direct-current electrical cardioversion","volume":"20","author":"Emilsson","year":"2000","journal-title":"Clin. Physiol."},{"key":"10.1016\/j.ahjo.2022.100183_bb0235","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0002-8703(98)70217-0","article-title":"Cardiac performance early after cardioversion from atrial fibrillation","volume":"136","author":"Raymond","year":"1998","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ahjo.2022.100183_bb0240","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijcard.2003.05.033","article-title":"Effects of sinus rhythm restoration in patients with persistent atrial fibrillation: a clinical, echocardiographic and hormonal study","volume":"96","author":"Wozakowska-Kaplon","year":"2004","journal-title":"Int. J. Cardiol."}],"container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666602222001008?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666602222001008?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:28:36Z","timestamp":1763000916000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666602222001008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":48,"alternative-id":["S2666602222001008"],"URL":"https:\/\/doi.org\/10.1016\/j.ahjo.2022.100183","relation":{},"ISSN":["2666-6022"],"issn-type":[{"value":"2666-6022","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical predictors of improvement in left ventricular ejection fraction in U.S. veterans with heart failure","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal Plus: Cardiology Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahjo.2022.100183","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100183"}}