{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:25:01Z","timestamp":1740183901479,"version":"3.37.3"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001948","name":"ASHP Research and Education Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001948","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005233","name":"American Nurses Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005233","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ahjo.2024.100470","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T11:36:47Z","timestamp":1729078607000},"page":"100470","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Medication optimization clinic decreases hospitalizations and mortality for patients with heart failure with reduced ejection fraction"],"prefix":"10.1016","volume":"47","author":[{"given":"James C.","family":"Coons","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Kliner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Mathier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh","family":"Mulukutla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floyd","family":"Thoma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Sezer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Keebler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"17","key":"10.1016\/j.ahjo.2024.100470_bb0005","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.jacc.2021.12.011","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"79","author":"Heidenreich","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"issue":"15","key":"10.1016\/j.ahjo.2024.100470_bb0010","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1016\/j.jacc.2023.12.024","article-title":"2024 ACC expert consensus decision pathway for treatment of heart failure with reduced ejection fraction: a report of the American College of Cardiology solution set oversight committee","volume":"83","author":"Maddox","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"issue":"17","key":"10.1016\/j.ahjo.2024.100470_bb0015","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1016\/j.jacc.2023.02.029","article-title":"Virtual care team guided management of patients with heart failure during hospitalization","volume":"81","author":"Bhatt","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"issue":"22","key":"10.1016\/j.ahjo.2024.100470_bb0020","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1016\/j.jacc.2022.03.338","article-title":"Electronic alerts to improve heart failure therapy in outpatient practice: a cluster randomized trial","volume":"79","author":"Ghazi","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"issue":"10367","key":"10.1016\/j.ahjo.2024.100470_bb0025","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/S0140-6736(22)02076-1","article-title":"Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial","volume":"400","author":"Mebazaa","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.ahjo.2024.100470_bb0030","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ahj.2019.09.012","article-title":"Care optimization through patient and hospital engagement clinical trial for heart failure: rationale and design of CONNECT-HF","volume":"220","author":"DeVore","year":"2020","journal-title":"Am. Heart J."},{"issue":"8","key":"10.1016\/j.ahjo.2024.100470_bb0035","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1001\/jama.2019.0710","article-title":"Effect of patient-centered transitional care services on clinical outcomes in patients hospitalized for heart failure: the PACT-HF randomized clinical trial","volume":"321","author":"Van Spall","year":"2019","journal-title":"JAMA"},{"issue":"9","key":"10.1016\/j.ahjo.2024.100470_bb0040","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1001\/jamacardio.2022.2496","article-title":"Alerting clinicians to 1-year mortality risk in patients hospitalized with heart failure: the REVEAL-HF randomized clinical trial","volume":"7","author":"Ahmad","year":"2022","journal-title":"JAMA Cardiol."},{"issue":"17","key":"10.1016\/j.ahjo.2024.100470_bb0045","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1016\/j.jacc.2023.02.047","article-title":"Team-based virtual nudges to overcome clinician inertia in guideline-directed medical therapy for heart failure","volume":"81","author":"Fonarow","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"issue":"9","key":"10.1016\/j.ahjo.2024.100470_bb0050","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1002\/ejhf.2271","article-title":"Heart failure drug titration, discontinuation, mortality and heart failure hospitalization risk: a multinational observational study (US, UK and Sweden)","volume":"23","author":"Savarese","year":"2021","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.ahjo.2024.100470_bb0055","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.amjcard.2022.11.025","article-title":"Impact of a medication optimization clinic on heart failure hospitalizations","volume":"188","author":"Coons","year":"2023","journal-title":"Am. J. Cardiol."},{"issue":"9","key":"10.1016\/j.ahjo.2024.100470_bb0060","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1161\/CIRCULATIONAHA.120.052926","article-title":"How should we sequence the treatments for heart failure and a reduced ejection fraction?: a redefinition of evidence-based medicine","volume":"143","author":"McMurray","year":"2021","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ahjo.2024.100470_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchf.2022.08.009","article-title":"Heart failure drug treatment-inertia, titration, and discontinuation: a multinational observational study (EVOLUTION HF)","volume":"11","author":"Savarese","year":"2023","journal-title":"JACC Heart Fail."},{"issue":"2","key":"10.1016\/j.ahjo.2024.100470_bb0070","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jchf.2021.09.004","article-title":"A systematic review and network meta-analysis of pharmacological treatment of heart failure with reduced ejection fraction","volume":"10","author":"Tromp","year":"2022","journal-title":"JACC Heart Fail."},{"issue":"20","key":"10.1016\/j.ahjo.2024.100470_bb0075","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1016\/j.jacc.2017.03.563","article-title":"Achieving a maximally tolerated beta-blocker dose in heart failure patients: is there room for improvement?","volume":"69","author":"Bhatt","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"issue":"7","key":"10.1016\/j.ahjo.2024.100470_bb0080","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/jamacardio.2020.0640","article-title":"Assessment of limitations to optimization of guideline-directed medical therapy in heart failure from the GUIDE-IT trial: a secondary analysis of a randomized clinical trial","volume":"5","author":"Fiuzat","year":"2020","journal-title":"JAMA Cardiol."},{"issue":"7","key":"10.1016\/j.ahjo.2024.100470_bb0085","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.cardfail.2023.03.012","article-title":"Pharmacist- and nurse-led medical optimization in heart failure: a systematic review and meta-analysis","volume":"29","author":"Zheng","year":"2023","journal-title":"J. Card. Fail."},{"issue":"1","key":"10.1016\/j.ahjo.2024.100470_bb0090","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jchf.2020.08.017","article-title":"Heart failure hospitalization and guideline-directed prescribing patterns among heart failure with reduced ejection fraction patients","volume":"9","author":"Srivastava","year":"2021","journal-title":"JACC Heart Fail."}],"container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666602224001137?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666602224001137?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T12:13:42Z","timestamp":1731500022000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666602224001137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":18,"alternative-id":["S2666602224001137"],"URL":"https:\/\/doi.org\/10.1016\/j.ahjo.2024.100470","relation":{},"ISSN":["2666-6022"],"issn-type":[{"type":"print","value":"2666-6022"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Medication optimization clinic decreases hospitalizations and mortality for patients with heart failure with reduced ejection fraction","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal Plus: Cardiology Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahjo.2024.100470","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100470"}}