{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T21:22:40Z","timestamp":1794604960868,"version":"4.9.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008469","name":"Filha","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008469","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008368","name":"Foundation for Finnish Tuberculosis Counterfeiting Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008368","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006706","name":"Tampere Tuberculosis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006706","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010133","name":"Aarne Koskelo Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.ahjo.2026.100904","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:14:03Z","timestamp":1790349243000},"page":"100904","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Meta-analysis of the histopathological features of surgically removed aortas classified according to the SCVP and AECVP consensus documents"],"prefix":"10.1016","volume":"71","author":[{"given":"Eemeli","family":"J\u00e4msen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kalfe\u0159t","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tero","family":"Halmesm\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Mennander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Paavonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Kholov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ahjo.2026.100904_bb0005","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1161\/CIR.0b013e3181d47d48","article-title":"2010 ACCF\/AHA\/AATS\/ACR\/ASA\/SCA\/SCAI\/SIR\/STS\/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease","volume":"121","author":"Hiratzka","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ahjo.2026.100904_bb0010","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1093\/eurheartj\/ehae179","volume":"45","author":"Mazzolai","year":"2024","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ahjo.2026.100904_bb0015","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-026-46006-x","article-title":"Towards a more reliable assessment of aortic diameters using a Bayesian Z-score","volume":"16","author":"Bindini","year":"2026","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ahjo.2026.100904_bb0020","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.carpath.2015.05.001","article-title":"Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. Cardiovasc Pathol off J Soc","volume":"24","author":"Stone","year":"2015","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0025","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.carpath.2016.03.002","volume":"25","author":"Halushka","year":"2016","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1055\/s-0042-1743536","article-title":"Differences in aortic histopathology in patients undergoing valve Reimplantation surgery for various clinical syndromes","volume":"10","author":"Tucker","year":"2022","journal-title":"AORTA"},{"key":"10.1016\/j.ahjo.2026.100904_bb0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ijcard.2020.04.011","article-title":"Impact of histopathological changes in ascending aortic diseases","volume":"311","author":"Amemiya","year":"2020","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0040","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13019-022-01864-0","article-title":"Ascending aortic wall degeneration in patients with bicuspid versus tricuspid aortic valve","volume":"17","author":"Mennander","year":"2022","journal-title":"J. Cardiothorac. Surg."},{"key":"10.1016\/j.ahjo.2026.100904_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.carpath.2024.107702","article-title":"Interplay of atherosclerosis and medial degeneration in human ascending aorta","volume":"74","author":"Huhta","year":"2025","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003583","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"18","author":"Page","year":"2021","journal-title":"PLoS Med."},{"key":"10.1016\/j.ahjo.2026.100904_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242015470","article-title":"Histopathological gap in aortic diseases: a prospective analysis","volume":"24","author":"Banceu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ahjo.2026.100904_bb0060","first-page":"3046","article-title":"Sub-classification of non-inflammatory and inflammatory surgical aortic aneurysms and the association of histological characteristics with potential risk factors","volume":"18","author":"Butcovan","year":"2019","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.ahjo.2026.100904_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/jcdd8020012","article-title":"A systematic histopathologic evaluation of type-a aortic dissections implies a uniform multiple-hit causation","volume":"8","author":"Grewal","year":"2021","journal-title":"J. Cardiovasc. Dev. Dis."},{"key":"10.1016\/j.ahjo.2026.100904_bb0070","article-title":"Sex differences in the histopathology of acute type a aortic dissections","author":"Grewal","year":"2024","journal-title":"Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.ahjo.2026.100904_bb0075","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1093\/ejcts\/ezaa440","article-title":"Histopathological changes in dilated ascending aorta associated with aortic valve cuspidity","volume":"59","author":"Karalko","year":"2021","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.ahjo.2026.100904_bb0080","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.jtcvs.2018.04.086","article-title":"Redefining the histopathologic profile of acute aortic syndromes: clinical and prognostic implications","volume":"156","author":"Leone","year":"2018","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.ahjo.2026.100904_bb0085","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.jtcvs.2019.08.108","article-title":"The complex interplay among atherosclerosis, inflammation, and degeneration in ascending thoracic aortic aneurysms","volume":"160","author":"Leone","year":"2020","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.ahjo.2026.100904_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2021.153542","article-title":"Ascending aorta dissection in a new classification system: Clinicopathological features of 62 cases","volume":"224","author":"Stejskal","year":"2021","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.ahjo.2026.100904_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2023.154526","article-title":"Histopathological findings of diseased ascending aortae with clinicopathological correlation - a single-Centre study of 160 cases","volume":"246","author":"Stejskal","year":"2023","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.ahjo.2026.100904_bb0100","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-92659-1","article-title":"Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components","volume":"11","author":"Yousef","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ahjo.2026.100904_bb0105","article-title":"Insights from the histopathologic analysis of acquired and genetic thoracic aortic aneurysms and dissections","volume":"51","author":"Buja","year":"2024","journal-title":"Tex. Heart Inst. J."},{"key":"10.1016\/j.ahjo.2026.100904_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacadv.2025.101682","article-title":"Pathobiology of aortic aneurysms and dissections","volume":"4","author":"Buja","year":"2025","journal-title":"JACC Adv"},{"key":"10.1016\/j.ahjo.2026.100904_bb0115","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.carpath.2017.05.008","article-title":"Histopathologic differences partially distinguish syndromic aortic diseases","volume":"30","author":"Waters","year":"2017","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.carpath.2021.107329","article-title":"Comparison of the damage to aorta wall in aortitis versus noninflammatory degenerative aortic diseases","volume":"52","author":"Amemiya","year":"2021","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.ahjo.2026.100904_bb0125","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242115640","article-title":"Evidence accumulates: patients with ascending aneurysms are strongly protected from atherosclerotic disease","volume":"24","author":"Waldron","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.ahjo.2026.100904_bb2000","doi-asserted-by":"crossref","DOI":"10.1111\/apm.70023","article-title":"Systematic morphological assesment of the ascending aorta dissection: Application of cardiovascular pathology consensus statement in tertiaty care hospital in Finland","volume":"133","author":"Chen","year":"2025","journal-title":"APMIS"}],"container-title":["American Heart Journal Plus: Cardiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266660222600193X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266660222600193X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T21:00:32Z","timestamp":1794603632000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S266660222600193X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":26,"alternative-id":["S266660222600193X"],"URL":"https:\/\/doi.org\/10.1016\/j.ahjo.2026.100904","relation":{},"ISSN":["2666-6022"],"issn-type":[{"value":"2666-6022","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Meta-analysis of the histopathological features of surgically removed aortas classified according to the SCVP and AECVP consensus documents","name":"articletitle","label":"Article Title"},{"value":"American Heart Journal Plus: Cardiology Research and Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ahjo.2026.100904","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100904"}}