{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T09:54:34Z","timestamp":1791971674302,"version":"4.3.4"},"reference-count":6,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":55,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Intensive Care"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.aicoj.2026.100042","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T19:19:46Z","timestamp":1772479186000},"page":"100042","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Clarifying physiology-guided subphenotyping of hypotension in early sepsis"],"prefix":"10.1016","volume":"16","author":[{"given":"Carlos","family":"Sanchez-Escalante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Teboul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aicoj.2026.100042_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.aicoj.2026.100043","article-title":"Comment on: physiology-guided subphenotyping of hypotension in early sepsis","author":"Ghataka","year":"2026","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.aicoj.2026.100042_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.aicoj.2025.100015","article-title":"Subphenotyping hypotension in early sepsis: a physiology-guided therapeutic approach","volume":"16","author":"Sanchez","year":"2026","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.aicoj.2026.100042_bib0015","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13613-025-01454-y","article-title":"Ability of diastolic arterial pressure to better characterize the severity of septic shock when adjusted for heart rate and norepinephrine dose","volume":"15","author":"Goury","year":"2025","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.aicoj.2026.100042_bib0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s13613-020-00658-8","article-title":"Diastolic shock index and clinical outcomes in patients with septic shock","volume":"10","author":"Ospina-Tasc\u00f3n","year":"2020","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.aicoj.2026.100042_bib0025","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s13613-025-01608-y","article-title":"Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool","volume":"15","author":"Bertrand","year":"2025","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.aicoj.2026.100042_bib0030","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1001\/jama.2025.20402","article-title":"Personalized hemodynamic resuscitation targeting capillary refill time in early septic shock: the ANDROMEDA-SHOCK-2 randomized clinical trial","volume":"334","author":"Hernandez","year":"2025","journal-title":"JAMA"}],"container-title":["Annals of Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582026000774?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582026000774?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T09:33:31Z","timestamp":1791970411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2110582026000774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":6,"alternative-id":["S2110582026000774"],"URL":"https:\/\/doi.org\/10.1016\/j.aicoj.2026.100042","relation":{},"ISSN":["2110-5820"],"issn-type":[{"value":"2110-5820","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clarifying physiology-guided subphenotyping of hypotension in early sepsis","name":"articletitle","label":"Article Title"},{"value":"Annals of Intensive Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aicoj.2026.100042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.aicoj.2026.100043","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.aicoj.2025.100015","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 de R\u00e9animation de Langue Fran\u00e7aise (French Intensive Care Society).","name":"copyright","label":"Copyright"}],"article-number":"100042"}}