{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:19:19Z","timestamp":1768677559717,"version":"3.49.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.ajcnut.2025.01.016","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T07:37:26Z","timestamp":1737704246000},"page":"882-891","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Describing the landscape of nutrition- and diet-related randomized controlled trials: metaresearch study of protocols published between 2012 and 2022"],"prefix":"10.1016","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0730-5424","authenticated-orcid":false,"given":"Fl\u00e1via Moraes","family":"Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Rodrigues","family":"Amorim Adegboye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celeste","family":"Naude","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cintia","family":"Curioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio S","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary S","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto","family":"Kac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Anne de Beyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Cook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila Cheikh","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew J","family":"Page","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Khandpur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sallie","family":"Lamb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally","family":"Hopewell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaima","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shona","family":"Kirtley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Bernardes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solange","family":"Dur\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colby J","family":"Vorland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1711-9310","authenticated-orcid":false,"given":"Michael Maia","family":"Schlussel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1S","key":"10.1016\/j.ajcnut.2025.01.016_bib1","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1016\/j.chest.2020.03.013","article-title":"Randomised controlled trials","volume":"158","author":"Zabor","year":"2020","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.ajcnut.2025.01.016_bib2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13063-016-1743-0","article-title":"Review and publication of protocol submissions to Trials\u2014what have we learned in 10 years?","volume":"18","author":"Li","year":"2016","journal-title":"Trials"},{"key":"10.1016\/j.ajcnut.2025.01.016_bib3","unstructured":"International Committee of Medical Journal Editors, Recommendations for the conduct, reporting, editing, and publication of scholarly work in medical journals [Internet]. [cited May 22, 2023]. Available from: https:\/\/www.icmje.org\/."},{"key":"10.1016\/j.ajcnut.2025.01.016_bib4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jclinepi.2022.05.014","article-title":"A\u00a0meta-research study of randomised controlled trials found infrequent and delayed availability of protocols","volume":"149","author":"Sch\u00f6nenberger","year":"2022","journal-title":"J.\u00a0Clin. Epidemiol."},{"issue":"1","key":"10.1016\/j.ajcnut.2025.01.016_bib5","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s13063-018-2510-1","article-title":"Promoting public access to clinical trial protocols: challenges and recommendations","volume":"19","author":"Chan","year":"2018","journal-title":"Trials"},{"key":"10.1016\/j.ajcnut.2025.01.016_bib6","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.e7586","article-title":"SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials","volume":"346","author":"Chan","year":"2013","journal-title":"BMJ"},{"issue":"6166","key":"10.1016\/j.ajcnut.2025.01.016_bib7","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1126\/science.1245317","article-title":"Social science. Promoting transparency in social science research","volume":"343","author":"Miguel","year":"2014","journal-title":"Science"},{"issue":"7572","key":"10.1016\/j.ajcnut.2025.01.016_bib8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/526182a","article-title":"How scientists fool themselves\u2014and how they can stop","volume":"526","author":"Nuzzo","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.ajcnut.2025.01.016_bib9","first-page":"12","article-title":"High impact nutrition and dietetics journals' use of publication procedures to increase research transparency, Res. Integr. Peer","volume":"5","author":"Gorman","year":"2020","journal-title":"Rev"},{"issue":"9","key":"10.1016\/j.ajcnut.2025.01.016_bib10","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2019-031259","article-title":"Endorsement of reporting guidelines and study registration by endocrine and internal medicine journals: meta-epidemiological study","volume":"9","author":"Zu\u00f1iga-Hernandez","year":"2019","journal-title":"BMJ Open"},{"issue":"3","key":"10.1016\/j.ajcnut.2025.01.016_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2005468","article-title":"Meta-research: why research on research matters","volume":"16","author":"Ioannidis","year":"2018","journal-title":"PLOS Biol"},{"issue":"12","key":"10.1016\/j.ajcnut.2025.01.016_bib12","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-064744","article-title":"Protocol for a meta-research study of protocols for diet or nutrition-related trials published in indexed journals: general aspects of study design, rationale and reporting limitations","volume":"12","author":"Silva","year":"2022","journal-title":"BMJ Open"},{"issue":"1","key":"10.1016\/j.ajcnut.2025.01.016_bib13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12937-017-0244-7","article-title":"Scope and quality of Cochrane reviews of nutrition interventions: a cross-sectional study","volume":"16","author":"Naude","year":"2017","journal-title":"Nutr. J."},{"issue":"6","key":"10.1016\/j.ajcnut.2025.01.016_bib14","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.jclinepi.2015.02.005","article-title":"Validation of a search strategy to identify\u00a0nutrition trials in PubMed using the relative recall method","volume":"68","author":"Dur\u00e3o","year":"2015","journal-title":"J.\u00a0Clin. Epidemiol."},{"issue":"6","key":"10.1016\/j.ajcnut.2025.01.016_bib15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-011188","article-title":"Reporting of planned statistical methods in published surgical randomised trial protocols: a protocol for a methodological systematic review","volume":"6","author":"Madden","year":"2016","journal-title":"BMJ Open"},{"issue":"1","key":"10.1016\/j.ajcnut.2025.01.016_bib16","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan-a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst. Rev."},{"key":"10.1016\/j.ajcnut.2025.01.016_bib17","unstructured":"RedCAP [Internet]. [cited November 4, 2022]. Available from: https:\/\/www.project-redcap.org\/.."},{"issue":"3","key":"10.1016\/j.ajcnut.2025.01.016_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000251","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials","volume":"7","author":"Schulz","year":"2010","journal-title":"PLOS Med"},{"key":"10.1016\/j.ajcnut.2025.01.016_bib19","doi-asserted-by":"crossref","first-page":"g1687","DOI":"10.1136\/bmj.g1687","article-title":"Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide","volume":"348","author":"Hoffmann","year":"2014","journal-title":"BMJ"},{"issue":"16","key":"10.1016\/j.ajcnut.2025.01.016_bib20","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1002\/cncr.33587","article-title":"The ever-increasing importance of cancer as a leading cause of premature death worldwide","volume":"127","author":"Bray","year":"2021","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.ajcnut.2025.01.016_bib21","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/advances\/nmy014","article-title":"Perspective: limiting dependence on nonrandomised studies and improving randomised trials in human nutrition research: why and how","volume":"9","author":"Trepanowski","year":"2018","journal-title":"Adv Nutr"},{"issue":"6","key":"10.1016\/j.ajcnut.2025.01.016_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1010139","article-title":"Ten simple rules for good research practice","volume":"18","author":"Schwab","year":"2022","journal-title":"PLOS Comput. Biol."},{"issue":"11","key":"10.1016\/j.ajcnut.2025.01.016_bib23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1177\/0141076820956799","article-title":"Reducing bias and improving transparency in medical research: a critical overview of the problems, progress and suggested next steps","volume":"113","author":"Bradley","year":"2020","journal-title":"J.\u00a0R. Soc. Med."},{"issue":"9912","key":"10.1016\/j.ajcnut.2025.01.016_bib24","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0140-6736(13)62329-6","article-title":"Biomedical research: increasing value, reducing waste","volume":"383","author":"Macleod","year":"2014","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.ajcnut.2025.01.016_bib25","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/s41562-021-01142-4","article-title":"Initial evidence of research quality of registered reports compared with the standard publishing model","volume":"5","author":"Soderberg","year":"2021","journal-title":"Nat. Hum. Behav."},{"issue":"3","key":"10.1016\/j.ajcnut.2025.01.016_bib26","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.2196\/jmir.6.3.e37","article-title":"Peer-review and publication of research protocols and proposals: a role for open access journals","volume":"6","author":"Eysenbach","year":"2004","journal-title":"J.\u00a0Med. Internet. Res."},{"issue":"9151","key":"10.1016\/j.ajcnut.2025.01.016_bib27","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0140-6736(98)07618-1","article-title":"How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing","volume":"353","author":"Chalmers","year":"1999","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.ajcnut.2025.01.016_bib28","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/s41562-018-0449-6","article-title":"Protocol transparency is vital for registered reports","volume":"2","author":"Chambers","year":"2018","journal-title":"Nat. Hum. Behav."},{"issue":"1","key":"10.1016\/j.ajcnut.2025.01.016_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/advances\/nmaa118","article-title":"Perspective: US documentation and regulation of human nutrition randomized controlled trials","volume":"12","author":"Weaver","year":"2021","journal-title":"Adv. Nutr."},{"issue":"5","key":"10.1016\/j.ajcnut.2025.01.016_bib30","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1093\/advances\/nmab045","article-title":"Perspective: planning and conducting statistical analyses for human nutrition randomized controlled trials: ensuring data quality and integrity","volume":"12","author":"Petersen","year":"2021","journal-title":"Adv. Nutr."},{"issue":"10","key":"10.1016\/j.ajcnut.2025.01.016_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.advnut.2024.100283","article-title":"Recommendations for designing, conducting, and reporting feeding trials in nutrition research","volume":"15","author":"Tien","year":"2024","journal-title":"Adv Nutr"},{"issue":"11","key":"10.1016\/j.ajcnut.2025.01.016_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2006930","article-title":"Reproducible research practices, transparency, and open access data in the biomedical literature, 2015\u20132017","volume":"16","author":"Wallach","year":"2018","journal-title":"PLOS Biol"},{"issue":"3","key":"10.1016\/j.ajcnut.2025.01.016_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001107","article-title":"Assessment of transparency indicators across the biomedical literature: how open is open?","volume":"19","author":"Serghiou","year":"2021","journal-title":"PLOS Biol"},{"issue":"9","key":"10.1016\/j.ajcnut.2025.01.016_bib34","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1038\/s41591-022-01989-8","article-title":"An update to SPIRIT and CONSORT reporting guidelines to enhance transparency in randomised trials","volume":"28","author":"Hopewell","year":"2022","journal-title":"Nat. Med."},{"key":"10.1016\/j.ajcnut.2025.01.016_bib35","author":"Schlussel","year":"2019","journal-title":"Open Science Framework"},{"issue":"5","key":"10.1016\/j.ajcnut.2025.01.016_bib36","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00394-023-03137-5","article-title":"Perspectives on the application of CONSORT guidelines to randomised controlled trials in nutrition","volume":"62","author":"Rigutto-Farebrother","year":"2023","journal-title":"Eur. J. Nutr."}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916525000164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916525000164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T13:49:27Z","timestamp":1743947367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916525000164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S0002916525000164"],"URL":"https:\/\/doi.org\/10.1016\/j.ajcnut.2025.01.016","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Describing the landscape of nutrition- and diet-related randomized controlled trials: metaresearch study of protocols published between 2012 and 2022","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajcnut.2025.01.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society for Nutrition.","name":"copyright","label":"Copyright"}]}}