{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:39:47Z","timestamp":1792773587736,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013200","name":"Government of Alberta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013200","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.ajcnut.2026.101467","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T15:03:23Z","timestamp":1786374203000},"page":"101467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial"],"prefix":"10.1016","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9884-2553","authenticated-orcid":false,"given":"Mari\u00eblle PKJ","family":"Engelen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine L","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn N","family":"Porter Starr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B","family":"Sawyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connie W","family":"Bales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Siervo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schuetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla M","family":"Prado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolaas EP","family":"Deutz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejso.2023.107074","article-title":"Malnutrition in cancer patients: causes, consequences and treatment options","volume":"50","author":"Arends","year":"2024","journal-title":"Eur. J. Surg. Oncol."},{"issue":"12","key":"10.1016\/j.ajcnut.2026.101467_bib2","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1200\/JCO.2012.45.2722","article-title":"Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index","volume":"31","author":"Martin","year":"2013","journal-title":"J. Clin. Oncol."},{"issue":"12","key":"10.1016\/j.ajcnut.2026.101467_bib3","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1200\/JCO.2015.63.6043","article-title":"Loss of muscle mass during chemotherapy is predictive for poor survival of patients with metastatic colorectal cancer","volume":"34","author":"Blauwhoff-Buskermolen","year":"2016","journal-title":"J. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.ajcnut.2026.101467_bib4","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.surg.2018.07.031","article-title":"Loss of muscle mass during preoperative chemotherapy as a prognosticator for poor survival in patients with colorectal liver metastases","volume":"165","author":"Okuno","year":"2019","journal-title":"Surgery"},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib5","first-page":"93","article-title":"An exploratory study of body composition as a determinant of epirubicin pharmacokinetics and toxicity, Cancer Chemother","volume":"67","author":"Prado","year":"2011","journal-title":"Pharmacol."},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0129742","article-title":"Negative impact of skeletal muscle loss after systemic chemotherapy in patients with unresectable colorectal cancer","volume":"10","author":"Miyamoto","year":"2015","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib7","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1093\/ajcn\/84.5.1163","article-title":"Dietary patterns in patients with advanced cancer: implications for anorexia-cachexia therapy","volume":"84","author":"Hutton","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.clnu.2016.07.015","article-title":"ESPEN guidelines on nutrition in cancer patients","volume":"36","author":"Arends","year":"2017","journal-title":"Clin. Nutr."},{"issue":"4","key":"10.1016\/j.ajcnut.2026.101467_bib9","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1080\/09553002.2018.1466209","article-title":"Amino acid kinetics and the response to nutrition in patients with cancer","volume":"95","author":"van der Meij","year":"2019","journal-title":"Int. J. Radiat. Biol."},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib10","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1101\/gad.276733.115","article-title":"Mechanisms of metabolic dysfunction in cancer-associated cachexia","volume":"30","author":"Petruzzelli","year":"2016","journal-title":"Genes Dev"},{"issue":"2","key":"10.1016\/j.ajcnut.2026.101467_bib11","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nrclinonc.2012.209","article-title":"Understanding the mechanisms and treatment options in cancer cachexia","volume":"10","author":"Fearon","year":"2013","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib12","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.clnu.2007.07.004","article-title":"Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy","volume":"26","author":"Dillon","year":"2007","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.ajcnut.2026.101467_bib13","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.clnesp.2020.11.016","article-title":"Protein Recommendation to Increase Muscle (PRIMe): study protocol for a randomized controlled pilot trial investigating the feasibility of a high protein diet to halt loss of muscle mass in patients with colorectal cancer","volume":"41","author":"Ford","year":"2021","journal-title":"Clin Nutr ESPEN"},{"issue":"7","key":"10.1016\/j.ajcnut.2026.101467_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2024.103604","article-title":"Feasibility of two levels of protein intake in patients with colorectal cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) randomized controlled pilot trial","volume":"9","author":"Ford","year":"2024","journal-title":"ESMO Open"},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib15","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.3945\/ajcn.112.045708","article-title":"Effect of tumor burden and subsequent surgical resection on skeletal muscle mass and protein turnover in colorectal cancer patients","volume":"96","author":"Williams","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib16","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.clnu.2011.05.008","article-title":"Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food","volume":"30","author":"Deutz","year":"2011","journal-title":"Clin. Nutr."},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib17","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.clnu.2012.05.003","article-title":"Normal protein anabolic response to hyperaminoacidemia in insulin-resistant patients with lung cancer cachexia","volume":"31","author":"Winter","year":"2012","journal-title":"Clin. Nutr."},{"issue":"9","key":"10.1016\/j.ajcnut.2026.101467_bib18","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1093\/annonc\/mdv271","article-title":"High anabolic potential of essential amino acid mixtures in advanced nonsmall cell lung cancer","volume":"26","author":"Engelen","year":"2015","journal-title":"Ann. Oncol."},{"issue":"3","key":"10.1016\/j.ajcnut.2026.101467_bib19","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/jcsm.12029","article-title":"Effects of oral meal feeding on whole body protein breakdown and protein synthesis in cachectic pancreatic cancer patients","volume":"6","author":"van Dijk","year":"2015","journal-title":"J. Cachexia Sarcopenia Muscle"},{"issue":"4","key":"10.1016\/j.ajcnut.2026.101467_bib20","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.3945\/ajcn.113.060228","article-title":"Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential?","volume":"98","author":"Prado","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"issue":"3","key":"10.1016\/j.ajcnut.2026.101467_bib21","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/jcsm.12173","article-title":"Presence of early stage cancer does not impair the early protein metabolic response to major surgery","volume":"8","author":"Engelen","year":"2017","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.ajcnut.2026.101467_bib22","article-title":"Effects of acute oral feeding on protein metabolism and muscle protein synthesis in individuals with cancer","volume":"67\u201368","author":"van der Meij","year":"2019","journal-title":"Nutrition"},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib23","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.clnu.2021.11.032","article-title":"The importance of protein sources to support muscle anabolism in cancer: an expert group opinion","volume":"41","author":"Ford","year":"2022","journal-title":"Clin. Nutr."},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib24","first-page":"39","article-title":"Protein anabolic resistance in cancer: does it really exist?","volume":"19","author":"Engelen","year":"2016","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care."},{"issue":"11","key":"10.1016\/j.ajcnut.2026.101467_bib25","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.3748\/wjg.v11.i11.1639","article-title":"Serum IL-6, TNF\u03b1 and CRP levels in Greek colorectal cancer patients: prognostic implications","volume":"11","author":"Nikiteas","year":"2005","journal-title":"World J. Gastroenterol."},{"issue":"3","key":"10.1016\/j.ajcnut.2026.101467_bib26","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.0663","article-title":"Association of baseline inflammation with effectiveness of nutritional support among patients with disease-related malnutrition: a secondary analysis of a randomized clinical trial","volume":"3","author":"Merker","year":"2020","journal-title":"JAMA Netw. Open"},{"issue":"8","key":"10.1016\/j.ajcnut.2026.101467_bib27","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.annonc.2021.05.793","article-title":"Nutritional support during the hospital stay reduces mortality in patients with different types of cancers: secondary analysis of a prospective randomized trial","volume":"32","author":"Bargetzi","year":"2021","journal-title":"Ann. Oncol."},{"issue":"Suppl 2","key":"10.1016\/j.ajcnut.2026.101467_bib28","doi-asserted-by":"crossref","first-page":"ii18","DOI":"10.1093\/annonc\/mdx815","article-title":"Insulin resistance and body composition in cancer patients","volume":"29","author":"Dev","year":"2018","journal-title":"Ann. Oncol."},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib29","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1016\/j.clnu.2018.10.022","article-title":"Increased amino acid turnover and myofibrillar protein breakdown in advanced cancer are associated with muscle weakness and impaired physical function","volume":"38","author":"van der Meij","year":"2019","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.ajcnut.2026.101467_bib30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.bone.2017.06.010","article-title":"Body composition by DXA","volume":"104","author":"Shepherd","year":"2017","journal-title":"Bone"},{"issue":"2","key":"10.1016\/j.ajcnut.2026.101467_bib31","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.ajcnut.2025.05.022","article-title":"Methodological standards for body composition-an expert-endorsed guide for research and clinical applications: levels, models, and terminology","volume":"122","author":"Prado","year":"2025","journal-title":"Am. J. Clin. Nutr."},{"issue":"4","key":"10.1016\/j.ajcnut.2026.101467_bib32","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0894-1130(12)80326-7","article-title":"Accuracy of the Jamar dynamometer","volume":"6","author":"H\u00e4rk\u00f6nen","year":"1993","journal-title":"J. Hand Ther."},{"issue":"4","key":"10.1016\/j.ajcnut.2026.101467_bib33","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3390\/jfmk9040274","article-title":"Accuracy and reliability of grip strength measurements: a comparative device analysis","volume":"9","author":"Gr\u00e4nicher","year":"2024","journal-title":"J. Funct. Morphol. Kinesiol."},{"issue":"1 Suppl","key":"10.1016\/j.ajcnut.2026.101467_bib34","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/0899-9007(95)00067-4","article-title":"Definition of standardized nutritional assessment and interventional pathways in oncology","volume":"12","author":"Ottery","year":"1996","journal-title":"Nutrition"},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib35","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1002\/jmv.26654","article-title":"Defining IL-6 levels in healthy individuals: a meta-analysis","volume":"93","author":"Said","year":"2021","journal-title":"J. Med. Virol."},{"issue":"10","key":"10.1016\/j.ajcnut.2026.101467_bib36","first-page":"2351","article-title":"The influence of age, sex, and race on the upper reference limit of serum C-reactive protein concentration","volume":"27","author":"Wener","year":"2000","journal-title":"J. Rheumatol."},{"issue":"10","key":"10.1016\/j.ajcnut.2026.101467_bib37","article-title":"Relationship between serum interleukin-6 levels, systemic immune-inflammation index, and other biomarkers across different rheumatoid arthritis severity levels","volume":"16","author":"Zeb","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.ajcnut.2026.101467_bib38","series-title":"StatPearls [Internet]","article-title":"C-reactive protein: clinical relevance and interpretation","author":"Singh","year":"2025"},{"key":"10.1016\/j.ajcnut.2026.101467_bib39","article-title":"Circulating TNF-\u03b1 levels in rheumatoid arthritis: a systematic review and meta-analysis and comparison to TNF-\u03b1 levels in sepsis","volume":"12","author":"Scherger","year":"2025","journal-title":"Ther. Adv. Infect. Dis."},{"key":"10.1016\/j.ajcnut.2026.101467_bib40","article-title":"CONSORT 2010 statement: extension to randomised pilot and feasibility trials","volume":"355","author":"Eldridge","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.ajcnut.2026.101467_bib41","series-title":"Amsterdam, The Netherlands","year":"2025"},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib43","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/gerona\/61.6.575","article-title":"Interleukin-6 in aging and chronic disease: a magnificent pathway","volume":"61","author":"Maggio","year":"2006","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"issue":"3","key":"10.1016\/j.ajcnut.2026.101467_bib44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1385\/CRIAI:28:3:187","article-title":"Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer","volume":"28","author":"Atreya","year":"2005","journal-title":"Clin. Rev. Allergy Immunol."},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib45","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3390\/membranes11050312","article-title":"A potential role of IL-6\/IL-6R in the development and management of colon cancer","volume":"11","author":"Turano","year":"2021","journal-title":"Membranes (Basel)"},{"issue":"11","key":"10.1016\/j.ajcnut.2026.101467_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165799","article-title":"Diurnal variation of circulating interleukin-6 in humans: a meta-analysis","volume":"11","author":"Nilsonne","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.ajcnut.2026.101467_bib47","article-title":"Role of high-sensitivity C-reactive protein (hs-CRP) in non-communicable diseases: a review","volume":"14","author":"Banait","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.ajcnut.2026.101467_bib48","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/124021","article-title":"Interpretation of C-reactive protein concentrations in critically ill patients","volume":"2013","author":"Lelubre","year":"2013","journal-title":"Biomed. Res. Int."},{"issue":"10188","key":"10.1016\/j.ajcnut.2026.101467_bib49","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1016\/S0140-6736(18)32776-4","article-title":"Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial","volume":"393","author":"Schuetz","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib50","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12950-025-00442-0","article-title":"Comparison of the inflammatory biomarkers IL- 6, TNF-\u03b1, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition: a secondary analysis of the randomized clinical trial EFFORT","volume":"22","author":"Wunderle","year":"2025","journal-title":"J. Inflamm. (Lond)."},{"issue":"5","key":"10.1016\/j.ajcnut.2026.101467_bib51","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/rr67","article-title":"Tumor necrosis factor-\u03b1 and muscle wasting: a cellular perspective","volume":"2","author":"Reid","year":"2001","journal-title":"Respir. Res."},{"issue":"3","key":"10.1016\/j.ajcnut.2026.101467_bib52","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1177\/1932296818805074","article-title":"Insulin units and conversion factors: a story of truth, boots, and faster half-truths","volume":"13","author":"Knopp","year":"2019","journal-title":"J. Diabetes Sci. Technol."},{"issue":"4","key":"10.1016\/j.ajcnut.2026.101467_bib53","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1007\/s00726-010-0715-z","article-title":"Proline and hydroxyproline metabolism: implications for animal and human nutrition","volume":"40","author":"Wu","year":"2011","journal-title":"Amino Acids"},{"issue":"7","key":"10.1016\/j.ajcnut.2026.101467_bib54","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/s41556-018-0118-z","article-title":"Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours","volume":"20","author":"Garcia-Bermudez","year":"2018","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.ajcnut.2026.101467_bib55","doi-asserted-by":"crossref","first-page":"605","DOI":"10.3892\/mmr.2021.12242","article-title":"Protective role of taurine against oxidative stress","volume":"24","author":"Baliou","year":"2021","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.ajcnut.2026.101467_bib56","first-page":"96","article-title":"Taurine and skeletal muscle function","volume":"18","author":"Spriet","year":"2015","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care."},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib57","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.clnu.2014.04.007","article-title":"Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group","volume":"33","author":"Deutz","year":"2014","journal-title":"Clin. Nutr."},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib58","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.3390\/cancers13061444","article-title":"Immunonutrition changes inflammatory response in colorectal cancer: results from a pilot randomized clinical trial","volume":"13","author":"Wierdak","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"6","key":"10.1016\/j.ajcnut.2026.101467_bib59","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1002\/jcsm.13638","article-title":"Tocilizumab for advanced non-small-cell lung cancer with concomitant cachexia: an observational study","volume":"15","author":"Du","year":"2024","journal-title":"J Cachexia Sarcopenia Muscle"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916526002765?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916526002765?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T15:40:05Z","timestamp":1792770005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916526002765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S0002916526002765"],"URL":"https:\/\/doi.org\/10.1016\/j.ajcnut.2026.101467","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ajcnut.2026.101467","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of American Society for Nutrition.","name":"copyright","label":"Copyright"}],"article-number":"101467"}}